<strong>Background:</strong> There are various health problems in rotating shift workers. There have been few studies on the associations of male climacteric symptoms with duration of working and lifestyle...<strong>Background:</strong> There are various health problems in rotating shift workers. There have been few studies on the associations of male climacteric symptoms with duration of working and lifestyle. <strong>Objective: </strong>The aim of this study was to determine the differences in male climacteric symptoms depending on the number of working years and to determine whether lifestyle habits differ depending on the number of working years in rotating shift workers. <strong>Methods:</strong> We collected participant’s data from the manufacturing companies in Japan during the period from March to May in 2017. We conducted a self-administered questionnaire survey in 1561 male rotating night shift workers. Male climacteric symptoms were evaluated by using the Aging Males’ Symptoms (AMS) rating scale. We analyzed 636 rotating shift workers aged over 40 years old whose all AMS data was collected. <strong>Results:</strong> A significant difference in psychological AMS score was found between men who had worked for 10 - 19 years (9.4 ± 3.9) and men who had worked for more than 40 years (7.6 ± 3.0) (p = 0.011). Sexual functional AMS score significantly differed depending on the number of working years (less than 10 years: 8.1 ± 3.9, 10 - 19 years: 9.8 ± 4.1, 20 - 29 years: 7.9 ± 3.3, 30 - 39 years: 9.3 ± 3.5, more than 40 years: 9.3 ± 3.5) (p < 0.001). The proportion of workers with a balanced meal intake was significantly lower in men who had worked for less than 10 years and the proportions of such workers were significantly higher in men who had worked for 10 - 19 years and for more than 40 years. The proportions of men who did not drink alcohol were high in men who had worked for less than 10 years and 20 - 29 years and low in men who had worked more than 30 years. <strong>Conclusion: </strong>Psychological AMS score and sexual functional AMS score are significantly different among the 5 groups according to the number of working years on rotating shift. In addition, well-balanced diet on day shift and reduction of alcohol drinking is a related-factor for long-term rotating night shift workers.展开更多
BACKGROUND: Sleep deprivation resulting from night shifts, is a major cause of burnout among physicians. Exogenous melatonin may improve sleep quality in night-shift workers. The study aims to compare the effectivenes...BACKGROUND: Sleep deprivation resulting from night shifts, is a major cause of burnout among physicians. Exogenous melatonin may improve sleep quality in night-shift workers. The study aims to compare the effectiveness of melatonin versus placebo on sleep effi ciency in emergency medicine(EM) residents. METHODS: A randomized, double-blind, replicated crossover trial was performed on EM residents. This study consisted of 4 phases within a month with intervention periods of 2 nights and washouts of 6 days. In our study, EM residents had nine-hour shifts on 6 consecutive days, 2 mornings, 2 evenings and 2 nights and then 2 days off. At the end of shifts' cycle, 24 EM residents were given 3 mg melatonin or placebo(12 in each arm of the study) for 2 consecutive nights after the second night shift with crossover to the other arm after a six-day off drug. This crossover intervention was repeated for two more another time. Finally, we created 48 cases and comparisons in each arm. Different items related to sleep quality were assessed and compared both within the same group and between the two groups. RESULTS: In the melatonin group, daytime sleepiness(calculated by Karolinska Sleep Scale) had a signifi cant reduction after taking the second dose of drug(P=0.003) but the same result was not observed when comparing the 2 groups. Mood status(calculated by Profile of Mood States) showed no remarkable difference between the 2 groups. CONCLUSION: Melatonin might have a limited benefi t on sleep quality in EM residents working night shifts.展开更多
Introduction: The exposure to shift works, and especially to night shift, goes against the circadian rythmicity of the social man, which brings about a multitude of disruptive effects on health. In a hospital environm...Introduction: The exposure to shift works, and especially to night shift, goes against the circadian rythmicity of the social man, which brings about a multitude of disruptive effects on health. In a hospital environment, such night shift is necessary so as to ensure the continuity of care. Sleep and vigilance disorders related to this work mode are frequent and often pose adaptation problems. The objective of this study is to detect the harmful effects of night shift on sleep, vigilance and the quality of life of nurses in Farhat Hached Teaching Hospital in Sousse. Material and Methods: It is a cross-sectional study carried out among two groups of nurses: one group performing a fixed night work and the other one working permanently during the day at Farhat Hached Teaching Hospital in Sousse. Data collection is mainly based on validated questionnaires evaluating sleep quality (Pittsburg sleep quality index), daytime sleepiness (Epworth sleepiness scale), sleep typology (Horne and Ostberg questionnaire), and the quality of life (SF-12). An objective evaluation of vigilance was realized by the study of reaction time and error rates to different tasks of “Super lab” software. Results: 50 night and 50 day nurses have been colligated. Both groups were age- and gender-matched. Sleep quality mean index was significantly higher among night nurses in comparison with day nurses (10.2 ± 5.9 versus 6.76 ± 5.16). After multivariate analysis, sleep quality was significantly correlated to age, department, schedule and the choice of schedule. Night shift was not related to daytime sleepiness. The objective analysis of vigilance showed that the reaction time to different tasks exploring the attentional mechanisms, as well as errors rate, were significantly more important among the night group. The mental score of the quality of life was significantly higher among day nurses. However, such difference was not significant with regard to physical score. Conclusion: The findings of our study highlight not only the alteration of the health and the well being of paramedical staff secondary to night shift, but also a possible threat to safety care lavished by these teams, which involves the necessity to undertake preventive measures on an individual and collective scale.展开更多
Prolonged night shift is associated with high burnout rate, but the physiological effects of a 16 h shift remain undetermined. Here we evaluated fatigue and stress via salivary assays to determine the correlation betw...Prolonged night shift is associated with high burnout rate, but the physiological effects of a 16 h shift remain undetermined. Here we evaluated fatigue and stress via salivary assays to determine the correlation between stress and fatigue and prolonged night shifts. Twenty-five nurses (9 men, 16 women;16 h night shift (n = 13), 8 h day shift (n = 12)) from Juntendo University Koshigaya Hospital were evaluated for four consecutive workdays separated by off days. Salivary samples were collected upon waking and before sleep on non-working days, before and after the day and night shifts, and before and after the break during the nocturnal schedule, and analyzed for levels of cortisol, chromogranin A, α-amylase activity and secretory immunoglobulin A (sIgA). On non-working days, cortisol levels showed similar kinetic pattern in both nurses. On working days, day-time nurses’ cortisol levels showed normal circadian pattern throughout the shift. Night nurses’ cortisol levels at the beginning of the shift were comparable to that of the normal morning elevation. α-Amylase activity in the night shift nurses was higher than day shift nurses through each period. No significant differences in chromogranin A and sIgA levels were detected between day and night shift workers. A 16 h night shift may cause marked circadian misalignment in cortisol levels.展开更多
Breast cancer is a serious public health concern in South Africa and globally. It is estimated that one in seven South Africans will develop cancer in their lifetime. According to a case-controlled study, 80% of cance...Breast cancer is a serious public health concern in South Africa and globally. It is estimated that one in seven South Africans will develop cancer in their lifetime. According to a case-controlled study, 80% of cancer cases are thought to be due to external, non-inherited factors, which could potentially have been prevented. The objectives of the current case-control study were: 1) to determine the relationship between night shift work and the development of breast cancer;2) to explore the relationship between night shift work and other types of cancer;3) to explore any difference between night shift work and breast cancer, and night shift work and other types of cancer. A total of 106 research participants were selected using non-probability, convenience sampling methods and interviewed using a structured questionnaire. Seventy-two (68%) of the women who were interviewed were black, while 32% (n = 35) were white. Of the 106 research participants, 82% (n = 87) had a history of being employed, while 18% (n = 19) had never been employed. Analysed data showed that 29% (n = 31) of the women had a history of working night shift. Of the 31 research participants who reported having worked night shift, 90% (n = 28) had actually done rotating shift work, rather than regular night shift work. The odds ratio of working night shift was found to be 1.24 (OR = 1.24, p = 0.615) higher in breast cancer research participants compared to research participants diagnosed with other types of cancer—odds ratio of 0.80 (p = 0.610). For rotational work, the OR was 1.445, indicating a higher risk than for shift work. It is recommended that the relationship between working night shift and breast cancer risk be explored further through cross-sectional and cohort studies.展开更多
Objective:To examine the association between sleep characteristics and night shift work and the risk of polycystic ovary syndrome(PCOS)in Chinese women and to investigate their relationship with infertility in PCOS.Me...Objective:To examine the association between sleep characteristics and night shift work and the risk of polycystic ovary syndrome(PCOS)in Chinese women and to investigate their relationship with infertility in PCOS.Methods:From March 21,2021 to April 31,2021,3927 Chinese women with or without PCOS were recruited online.All participants completed WeChat-based electronic questionnaires.Sleep characteristics were measured using the Pittsburgh sleep quality index.Results:A total of 2871 women were included in the final analysis.Sleep duration(odds ratio[OR],0.857;95%confidence interval[CI],0.763-0.963),sleep midpoint(OR,1.142;95%CI,1.049-1.244),sleep disturbance(OR,1.320;95%CI,0.957-1.146),daytime dysfunction(OR,1.136;95%CI,1.030-1.253),and night shift work(OR,1.628;95%CI,1.264-2.097)were associated with a higher risk of PCOS.After adjusting for confounders,including age,body mass index,smoking status,and coffee and tea drinking status,sleep disturbance(OR,1.314;95%CI,1.111-1.555),daytime dysfunction(OR,1.143;95%CI,1.034-1.264),and night shift work(OR,1.800;95%CI,1.388-2.333)remained associated.In addition,sleep disturbance(OR,1.887;95%CI,1.400-2.542)and subjective sleep quality(OR,1.299;95%CI,1.037-1.627)were associated with infertility in women with PCOS,and sleep disturbance(OR,1.750;95%CI,1.281-2.390)remained significant after adjusting for confounders.Conclusions:Sleep disturbance,daytime dysfunction,and night shift work are significantly associated with PCOS.Screening for sleep disturbances and providing appropriate treatment could be potential strategies for managing PCOS and its long-term complications.展开更多
目的：比较轮值夜班的护士与非轮值夜班的护士排尿日记的差异。方法：选择2014年1月至6月期间一直在北京大学人民医院住院病房工作的女性护士共58名,入选的护士年龄为20～43岁,其中28名护士在这半年内轮值夜班,作为夜班组,平均年龄为（2...目的：比较轮值夜班的护士与非轮值夜班的护士排尿日记的差异。方法：选择2014年1月至6月期间一直在北京大学人民医院住院病房工作的女性护士共58名,入选的护士年龄为20～43岁,其中28名护士在这半年内轮值夜班,作为夜班组,平均年龄为（26.75±4.11）岁,另外30名护士在这半年内无需轮值夜班,作为白班组,平均年龄为（27.80±5.60）岁。在这半年的最后1周记录其排尿日记,并要求在记录期间保证每日摄水量控制在1 500～2 000 m L。比较两组护士正常睡眠时的夜尿情况,并比较相应的8 h时间段内排尿情况的差异。结果：值夜班的护士与值白班的护士相比,正常睡眠时夜间排尿量[125 m L（0～660 m L）vs.0 m L（0～340 m L）]及夜间排尿次数[0.5次（0～2.4次）vs.0次（0～2次）]明显增加（P〈0.05）,而且在连续1周的记录中,夜班护士在值完夜班后的2天内夜间排尿量比值夜班前明显增加（P〈0.01）。夜班组护士与白班组护士相比,在下午的8 h时间段（2 pm—10 pm）内,排尿量[（542.35±204.66）m L vs.（675.62±256.09）m L]和排尿次数[（2.24±0.69）次vs.（2.91±0.73）次]明显减少（P〈0.05）。在夜间的8 h时间段（10 pm—6 am）内,夜班组护士与白班组护士相比,排尿量[（309.74±162.74）m L vs.（199.38±153.98）m L,P=0.01]和排尿次数[（1.31±0.52）次vs.（0.82±0.55）次,P〈0.01）]均明显增加。结论：轮值夜班明显影响护士的排尿,增加夜尿量及夜尿次数。展开更多
文摘<strong>Background:</strong> There are various health problems in rotating shift workers. There have been few studies on the associations of male climacteric symptoms with duration of working and lifestyle. <strong>Objective: </strong>The aim of this study was to determine the differences in male climacteric symptoms depending on the number of working years and to determine whether lifestyle habits differ depending on the number of working years in rotating shift workers. <strong>Methods:</strong> We collected participant’s data from the manufacturing companies in Japan during the period from March to May in 2017. We conducted a self-administered questionnaire survey in 1561 male rotating night shift workers. Male climacteric symptoms were evaluated by using the Aging Males’ Symptoms (AMS) rating scale. We analyzed 636 rotating shift workers aged over 40 years old whose all AMS data was collected. <strong>Results:</strong> A significant difference in psychological AMS score was found between men who had worked for 10 - 19 years (9.4 ± 3.9) and men who had worked for more than 40 years (7.6 ± 3.0) (p = 0.011). Sexual functional AMS score significantly differed depending on the number of working years (less than 10 years: 8.1 ± 3.9, 10 - 19 years: 9.8 ± 4.1, 20 - 29 years: 7.9 ± 3.3, 30 - 39 years: 9.3 ± 3.5, more than 40 years: 9.3 ± 3.5) (p < 0.001). The proportion of workers with a balanced meal intake was significantly lower in men who had worked for less than 10 years and the proportions of such workers were significantly higher in men who had worked for 10 - 19 years and for more than 40 years. The proportions of men who did not drink alcohol were high in men who had worked for less than 10 years and 20 - 29 years and low in men who had worked more than 30 years. <strong>Conclusion: </strong>Psychological AMS score and sexual functional AMS score are significantly different among the 5 groups according to the number of working years on rotating shift. In addition, well-balanced diet on day shift and reduction of alcohol drinking is a related-factor for long-term rotating night shift workers.
文摘BACKGROUND: Sleep deprivation resulting from night shifts, is a major cause of burnout among physicians. Exogenous melatonin may improve sleep quality in night-shift workers. The study aims to compare the effectiveness of melatonin versus placebo on sleep effi ciency in emergency medicine(EM) residents. METHODS: A randomized, double-blind, replicated crossover trial was performed on EM residents. This study consisted of 4 phases within a month with intervention periods of 2 nights and washouts of 6 days. In our study, EM residents had nine-hour shifts on 6 consecutive days, 2 mornings, 2 evenings and 2 nights and then 2 days off. At the end of shifts' cycle, 24 EM residents were given 3 mg melatonin or placebo(12 in each arm of the study) for 2 consecutive nights after the second night shift with crossover to the other arm after a six-day off drug. This crossover intervention was repeated for two more another time. Finally, we created 48 cases and comparisons in each arm. Different items related to sleep quality were assessed and compared both within the same group and between the two groups. RESULTS: In the melatonin group, daytime sleepiness(calculated by Karolinska Sleep Scale) had a signifi cant reduction after taking the second dose of drug(P=0.003) but the same result was not observed when comparing the 2 groups. Mood status(calculated by Profile of Mood States) showed no remarkable difference between the 2 groups. CONCLUSION: Melatonin might have a limited benefi t on sleep quality in EM residents working night shifts.
文摘Introduction: The exposure to shift works, and especially to night shift, goes against the circadian rythmicity of the social man, which brings about a multitude of disruptive effects on health. In a hospital environment, such night shift is necessary so as to ensure the continuity of care. Sleep and vigilance disorders related to this work mode are frequent and often pose adaptation problems. The objective of this study is to detect the harmful effects of night shift on sleep, vigilance and the quality of life of nurses in Farhat Hached Teaching Hospital in Sousse. Material and Methods: It is a cross-sectional study carried out among two groups of nurses: one group performing a fixed night work and the other one working permanently during the day at Farhat Hached Teaching Hospital in Sousse. Data collection is mainly based on validated questionnaires evaluating sleep quality (Pittsburg sleep quality index), daytime sleepiness (Epworth sleepiness scale), sleep typology (Horne and Ostberg questionnaire), and the quality of life (SF-12). An objective evaluation of vigilance was realized by the study of reaction time and error rates to different tasks of “Super lab” software. Results: 50 night and 50 day nurses have been colligated. Both groups were age- and gender-matched. Sleep quality mean index was significantly higher among night nurses in comparison with day nurses (10.2 ± 5.9 versus 6.76 ± 5.16). After multivariate analysis, sleep quality was significantly correlated to age, department, schedule and the choice of schedule. Night shift was not related to daytime sleepiness. The objective analysis of vigilance showed that the reaction time to different tasks exploring the attentional mechanisms, as well as errors rate, were significantly more important among the night group. The mental score of the quality of life was significantly higher among day nurses. However, such difference was not significant with regard to physical score. Conclusion: The findings of our study highlight not only the alteration of the health and the well being of paramedical staff secondary to night shift, but also a possible threat to safety care lavished by these teams, which involves the necessity to undertake preventive measures on an individual and collective scale.
文摘Prolonged night shift is associated with high burnout rate, but the physiological effects of a 16 h shift remain undetermined. Here we evaluated fatigue and stress via salivary assays to determine the correlation between stress and fatigue and prolonged night shifts. Twenty-five nurses (9 men, 16 women;16 h night shift (n = 13), 8 h day shift (n = 12)) from Juntendo University Koshigaya Hospital were evaluated for four consecutive workdays separated by off days. Salivary samples were collected upon waking and before sleep on non-working days, before and after the day and night shifts, and before and after the break during the nocturnal schedule, and analyzed for levels of cortisol, chromogranin A, α-amylase activity and secretory immunoglobulin A (sIgA). On non-working days, cortisol levels showed similar kinetic pattern in both nurses. On working days, day-time nurses’ cortisol levels showed normal circadian pattern throughout the shift. Night nurses’ cortisol levels at the beginning of the shift were comparable to that of the normal morning elevation. α-Amylase activity in the night shift nurses was higher than day shift nurses through each period. No significant differences in chromogranin A and sIgA levels were detected between day and night shift workers. A 16 h night shift may cause marked circadian misalignment in cortisol levels.
文摘Breast cancer is a serious public health concern in South Africa and globally. It is estimated that one in seven South Africans will develop cancer in their lifetime. According to a case-controlled study, 80% of cancer cases are thought to be due to external, non-inherited factors, which could potentially have been prevented. The objectives of the current case-control study were: 1) to determine the relationship between night shift work and the development of breast cancer;2) to explore the relationship between night shift work and other types of cancer;3) to explore any difference between night shift work and breast cancer, and night shift work and other types of cancer. A total of 106 research participants were selected using non-probability, convenience sampling methods and interviewed using a structured questionnaire. Seventy-two (68%) of the women who were interviewed were black, while 32% (n = 35) were white. Of the 106 research participants, 82% (n = 87) had a history of being employed, while 18% (n = 19) had never been employed. Analysed data showed that 29% (n = 31) of the women had a history of working night shift. Of the 31 research participants who reported having worked night shift, 90% (n = 28) had actually done rotating shift work, rather than regular night shift work. The odds ratio of working night shift was found to be 1.24 (OR = 1.24, p = 0.615) higher in breast cancer research participants compared to research participants diagnosed with other types of cancer—odds ratio of 0.80 (p = 0.610). For rotational work, the OR was 1.445, indicating a higher risk than for shift work. It is recommended that the relationship between working night shift and breast cancer risk be explored further through cross-sectional and cohort studies.
文摘Objective:To examine the association between sleep characteristics and night shift work and the risk of polycystic ovary syndrome(PCOS)in Chinese women and to investigate their relationship with infertility in PCOS.Methods:From March 21,2021 to April 31,2021,3927 Chinese women with or without PCOS were recruited online.All participants completed WeChat-based electronic questionnaires.Sleep characteristics were measured using the Pittsburgh sleep quality index.Results:A total of 2871 women were included in the final analysis.Sleep duration(odds ratio[OR],0.857;95%confidence interval[CI],0.763-0.963),sleep midpoint(OR,1.142;95%CI,1.049-1.244),sleep disturbance(OR,1.320;95%CI,0.957-1.146),daytime dysfunction(OR,1.136;95%CI,1.030-1.253),and night shift work(OR,1.628;95%CI,1.264-2.097)were associated with a higher risk of PCOS.After adjusting for confounders,including age,body mass index,smoking status,and coffee and tea drinking status,sleep disturbance(OR,1.314;95%CI,1.111-1.555),daytime dysfunction(OR,1.143;95%CI,1.034-1.264),and night shift work(OR,1.800;95%CI,1.388-2.333)remained associated.In addition,sleep disturbance(OR,1.887;95%CI,1.400-2.542)and subjective sleep quality(OR,1.299;95%CI,1.037-1.627)were associated with infertility in women with PCOS,and sleep disturbance(OR,1.750;95%CI,1.281-2.390)remained significant after adjusting for confounders.Conclusions:Sleep disturbance,daytime dysfunction,and night shift work are significantly associated with PCOS.Screening for sleep disturbances and providing appropriate treatment could be potential strategies for managing PCOS and its long-term complications.
文摘目的：比较轮值夜班的护士与非轮值夜班的护士排尿日记的差异。方法：选择2014年1月至6月期间一直在北京大学人民医院住院病房工作的女性护士共58名,入选的护士年龄为20～43岁,其中28名护士在这半年内轮值夜班,作为夜班组,平均年龄为（26.75±4.11）岁,另外30名护士在这半年内无需轮值夜班,作为白班组,平均年龄为（27.80±5.60）岁。在这半年的最后1周记录其排尿日记,并要求在记录期间保证每日摄水量控制在1 500～2 000 m L。比较两组护士正常睡眠时的夜尿情况,并比较相应的8 h时间段内排尿情况的差异。结果：值夜班的护士与值白班的护士相比,正常睡眠时夜间排尿量[125 m L（0～660 m L）vs.0 m L（0～340 m L）]及夜间排尿次数[0.5次（0～2.4次）vs.0次（0～2次）]明显增加（P〈0.05）,而且在连续1周的记录中,夜班护士在值完夜班后的2天内夜间排尿量比值夜班前明显增加（P〈0.01）。夜班组护士与白班组护士相比,在下午的8 h时间段（2 pm—10 pm）内,排尿量[（542.35±204.66）m L vs.（675.62±256.09）m L]和排尿次数[（2.24±0.69）次vs.（2.91±0.73）次]明显减少（P〈0.05）。在夜间的8 h时间段（10 pm—6 am）内,夜班组护士与白班组护士相比,排尿量[（309.74±162.74）m L vs.（199.38±153.98）m L,P=0.01]和排尿次数[（1.31±0.52）次vs.（0.82±0.55）次,P〈0.01）]均明显增加。结论：轮值夜班明显影响护士的排尿,增加夜尿量及夜尿次数。
