A series of novel 2-（1-substituted-1,11-undecylidene）-5-arylimino-△^3-1,3,4-thiadiazolines （4） were synthesized and their structure was characterized by ^1H NMR, ^13C NMR and elemental analysis. Their solubility ...A series of novel 2-（1-substituted-1,11-undecylidene）-5-arylimino-△^3-1,3,4-thiadiazolines （4） were synthesized and their structure was characterized by ^1H NMR, ^13C NMR and elemental analysis. Their solubility in both polar and non-polar solvents is significantly improved owing to the introduction of ethyl or methylthio group at cyclododecyl ring as compared with parent compounds [1, 2-（1,11-undecylidene）-5-arylimino-△^3-1,3,4-thiadiazolines]. However, their fungicidal activity against Rhizoctonia solani is less than that of parent compounds. X-ray diffraction analysis of a representative compound （4d） showed that the conformation of 12-membered ring is still [3333], in which the ethyl group present at the side-exo position and the thiadiazoline ring at the comer carbon. The thiadiazoline plane is perpendicular to the cyclododecyl one.展开更多
A series of new 1,3,4 thiadiazoline derivatives containing nitroimino were synthesized by cyclization, nitration, alkylation with carboxylic acid and thiosemicarbazide.Their structures were confirmed by IR, 1H NMR and...A series of new 1,3,4 thiadiazoline derivatives containing nitroimino were synthesized by cyclization, nitration, alkylation with carboxylic acid and thiosemicarbazide.Their structures were confirmed by IR, 1H NMR and elemental analysis .The bioassay of all title compounds was carried out.展开更多
基金supports from the National Basic Research Program of China(No. 2003CB 114407)
文摘A series of novel 2-（1-substituted-1,11-undecylidene）-5-arylimino-△^3-1,3,4-thiadiazolines （4） were synthesized and their structure was characterized by ^1H NMR, ^13C NMR and elemental analysis. Their solubility in both polar and non-polar solvents is significantly improved owing to the introduction of ethyl or methylthio group at cyclododecyl ring as compared with parent compounds [1, 2-（1,11-undecylidene）-5-arylimino-△^3-1,3,4-thiadiazolines]. However, their fungicidal activity against Rhizoctonia solani is less than that of parent compounds. X-ray diffraction analysis of a representative compound （4d） showed that the conformation of 12-membered ring is still [3333], in which the ethyl group present at the side-exo position and the thiadiazoline ring at the comer carbon. The thiadiazoline plane is perpendicular to the cyclododecyl one.
文摘A series of new 1,3,4 thiadiazoline derivatives containing nitroimino were synthesized by cyclization, nitration, alkylation with carboxylic acid and thiosemicarbazide.Their structures were confirmed by IR, 1H NMR and elemental analysis .The bioassay of all title compounds was carried out.
