Social dysfunction is a risk factor for several neuropsychiatric illnesses.Previous studies have shown that the lateral septum(LS)-related pathway plays a critical role in mediating social behaviors.Howeve r,the role ...Social dysfunction is a risk factor for several neuropsychiatric illnesses.Previous studies have shown that the lateral septum(LS)-related pathway plays a critical role in mediating social behaviors.Howeve r,the role of the connections between the LS and its downstream brain regions in social behavio rs remains unclea r.In this study,we conducted a three-chamber test using electrophysiological and chemogenetic approaches in mice to determine how LS projections to ventral CA1(vCA1)influence sociability.Our res ults showed that gamma-aminobutyric acid(GABA)-e rgic neuro ns were activated following social experience,and that social behavio rs were enhanced by chemogenetic modulation of these neurons.Moreover,LS GABAergic neurons extended their functional neural connections via vCA1 glutamatergic pyramidal neurons,and regulating LSGABA→vCA1Gluneural projections affected social behaviors,which were impeded by suppressing LSprojecting vCA1 neuronal activity or inhibiting GABAAreceptors in vCA1.These findings support the hypothesis that LS inputs to the vCA1 can control social prefe rences and social novelty behaviors.These findings provide new insights rega rding the neural circuits that regulate sociability.展开更多
Satellite communications is not only a key technical for students who major in information subject must know well, but also a satellite cultural background course at the information age. Based on the current situation...Satellite communications is not only a key technical for students who major in information subject must know well, but also a satellite cultural background course at the information age. Based on the current situation and characteristics of Universities of 211 Project, such as teaching objectives, course settings, and too much categories of professional courses but class hour reduced. From the point of view of teaching contents and methods, the reform contents and the characteristic requirements of the satellite communications course are presented, especially, the proposed reform to satellite communications materials and experimental content can meet the needs of the new times.展开更多
With the advancement of the construction of emerging engineering education,the reform of practical teaching has become an important task of higher engineering education.This article takes the course“Linux Operating S...With the advancement of the construction of emerging engineering education,the reform of practical teaching has become an important task of higher engineering education.This article takes the course“Linux Operating System Fundamentals”as an example to explore practical teaching reform in the context of emerging engineering education.By analyzing the current situation and problems in course practical teaching,we proposed practical teaching reforms such as online experiments,practical content updates,project-based engineering practices,and diversified evaluation models,and designed corresponding implementation plans.Practice has proved that this reform can improve students’learning interest and engineering practical skills,and cultivate outstanding engineers with innovative spirit and practical skills.展开更多
基金supported by the National Natural Science Foundation of China,No.82171521(to CL)the Special Funds ofTaishan Scholars Project of Shandong Province,No.tsqn202211368(to CL)+2 种基金the Natural Science Foundation of Shandong Province,Nos.ZR2022YQ65(to CL),ZR2021MH073(to CL),ZR2019PH109(to WW)the Projects of Medical and Health Technology Development Program in Shandong Province,China,Nos.202003090720(to DZ),202003070728(to JL),2019 WS329(to DW)the Scientific Research Foundation of Binzhou Medical University,No.BY2018KJ21(to DW)。
文摘Social dysfunction is a risk factor for several neuropsychiatric illnesses.Previous studies have shown that the lateral septum(LS)-related pathway plays a critical role in mediating social behaviors.Howeve r,the role of the connections between the LS and its downstream brain regions in social behavio rs remains unclea r.In this study,we conducted a three-chamber test using electrophysiological and chemogenetic approaches in mice to determine how LS projections to ventral CA1(vCA1)influence sociability.Our res ults showed that gamma-aminobutyric acid(GABA)-e rgic neuro ns were activated following social experience,and that social behavio rs were enhanced by chemogenetic modulation of these neurons.Moreover,LS GABAergic neurons extended their functional neural connections via vCA1 glutamatergic pyramidal neurons,and regulating LSGABA→vCA1Gluneural projections affected social behaviors,which were impeded by suppressing LSprojecting vCA1 neuronal activity or inhibiting GABAAreceptors in vCA1.These findings support the hypothesis that LS inputs to the vCA1 can control social prefe rences and social novelty behaviors.These findings provide new insights rega rding the neural circuits that regulate sociability.
文摘Satellite communications is not only a key technical for students who major in information subject must know well, but also a satellite cultural background course at the information age. Based on the current situation and characteristics of Universities of 211 Project, such as teaching objectives, course settings, and too much categories of professional courses but class hour reduced. From the point of view of teaching contents and methods, the reform contents and the characteristic requirements of the satellite communications course are presented, especially, the proposed reform to satellite communications materials and experimental content can meet the needs of the new times.
基金2023 China University of Geosciences(Beijing)Undergraduate Education Quality Improvement Plan Construction Project,including“Linux Operating System”Practical Teaching Reform(Project number:JG202215)“University Computer”Online Experiment Construction(Project number:JG202216)+1 种基金CUGB-Zhonggong Computer Science and Technology Off-Campus Practical Teaching Base(Project number:SSJJD202201)Ministry of Education Fund Project:Research and Development of Computer Vision Practical Courses Based on Deep Learning(Project number:2022BC003)。
文摘With the advancement of the construction of emerging engineering education,the reform of practical teaching has become an important task of higher engineering education.This article takes the course“Linux Operating System Fundamentals”as an example to explore practical teaching reform in the context of emerging engineering education.By analyzing the current situation and problems in course practical teaching,we proposed practical teaching reforms such as online experiments,practical content updates,project-based engineering practices,and diversified evaluation models,and designed corresponding implementation plans.Practice has proved that this reform can improve students’learning interest and engineering practical skills,and cultivate outstanding engineers with innovative spirit and practical skills.
