Management of the Pointe-Noire Forest requires high-performance tools for simulating tree and stand growth and assessing the sustainability of plantations. Modelling the dynamics of even-aged and mono-species stands i...Management of the Pointe-Noire Forest requires high-performance tools for simulating tree and stand growth and assessing the sustainability of plantations. Modelling the dynamics of even-aged and mono-species stands is a very active research topic. The approaches adopted by researchers vary according to the objectives and species considered: dendrometrical, Eco physiological or architectural. Thanks to the particular nature of these plantations and the trial set-up, it will be possible to explore the various aspects of production, clearly separating the part linked to genetics (three clones tested) from the part linked to the environment (via fertilisation) and the part associated with competition between trees (via planting densities and thinning regimes). This study will make a major contribution to the applicability of the self-thinning line and the RDI (Reineke Density Index) (Reineke, 1933) to fast-growing plantations. This research work will contribute to two points: 1) product diversification, which is a way of coping with international variations in timber markets, and 2) understanding how ecosystems function in exceptionally poor conditions, which will then enable the environmental impacts of the various recommended silvicultural itineraries to be assessed. The results obtained show that competition between trees in a stand of eucalyptus at very high density (10,000 stems/ha) and in two environments of very contrasting fertility is different depending on the clone. The decision on the date of the first thinning with a view to silviculture for timber and energy wood, which aims to ensure sustained and sustainable production of eucalyptus wood in these soils, should be taken between 12 and 14 months. The competition band is strong between 14 and 17 months, when the RDI = 0.8 is double that observed at 12 months.展开更多
Introduction: Breast cancer is the leading cancer and the leading cause of cancer death in women worldwide. The objective of our study was to describe the epidemiological, clinical and therapeutic aspects of breast ca...Introduction: Breast cancer is the leading cancer and the leading cause of cancer death in women worldwide. The objective of our study was to describe the epidemiological, clinical and therapeutic aspects of breast cancer at the General Hospital of Loandjili in Pointe Noire. Patients and Methods: This was a descriptive and cross-sectional study that took place in the Cancer Department of the General Hospital of Loandjili in Pointe Noire during the period from January 1st, 2012 to December 31st, 2016 for duration of 5 years. 54 records of patients over 18 years of age with histological evidence were collected. The variables studied were: age, level of education, time to presentation, telltale sign, stage of extension, histological type, and histological grade. Chi-square test was used to compare variables and groups. Results: At the end of this study, we collected 54 files of breast cancer patients from 150 patients hospitalized in the Cancer Department. The frequency of breast cancer was 36%. The average age was 50 ± 13.6 years;the extremes were 27 years and 79 years. The most represented age group was from 37 to 40 years old with a percentage of 28%. The patient’s level of study was primary in the majority of cases (57%). The most represented histological type was invasive ductal carcinoma, (100%). The majority of patients arrived at advanced stages 44.4% and metastatic stages 26%. Patients were treated in most of cases by chemotherapy (82%), surgery (42%) and radiotherapy (10%). There was a correlation between time of presentation and stage of extension. Conclusion: Breast cancer is the first cancer of the woman in Pointe Noire. Patients arrive at advanced stages;the most common histological type is invasive ductal carcinoma. The presentation time is correlated with the extension stage. These results suggest the establishment of a cancer control program in developing countries.展开更多
The synthesis of geological and petroleum research undertaken in the coastal Sedimentary Basin of the Pointe-Noire region enabled the establishment of a lithostratigraphic scale. It has been observed that the order in...The synthesis of geological and petroleum research undertaken in the coastal Sedimentary Basin of the Pointe-Noire region enabled the establishment of a lithostratigraphic scale. It has been observed that the order in which the series observed in outcrop and those encountered by deep wells succeed each other has allowed a value to be given to this relative scale. The study area corresponds to a longitudinal tectonic accident, fault or flexure. It belongs to the Cretaceous and Tertiary coastal sedimentary basin covered by the Plio-Pleistocene age formations (series of circuses), formed of highly permeable sands comprising multiple resistant horizons that store large bodies of water whose reserves are considered very important. Hydrographic network is composed of four main basins with a mediocre size. The quality of this groundwater is considered to be satisfactory for household consumption, but the sustainable management of these reserves requires constant checks on their quality as well as on the level of the reserves. All these resources put the agglomeration of Pointe-Noire close to large exploitable water reserves that meet the need for drinking water, even if, on the whole, the agglomeration is still experiencing many difficulties in terms of its drinking water supply.展开更多
Prevalence of hepatitis B in Pointe-Noire is 23%. The objective of this study was to evaluate the level of therapeutic management of patients with hepatitis B in Pointe-Noire. Methods: A retrospective, cross-sectional...Prevalence of hepatitis B in Pointe-Noire is 23%. The objective of this study was to evaluate the level of therapeutic management of patients with hepatitis B in Pointe-Noire. Methods: A retrospective, cross-sectional, descriptive and analytical study. Results: 302 patients included: 217 (72%) men and 85 (28%) women of median age 40 years. The viral load was measured in 140 (46%) patients and in 162 (54%), the viral load was not measured. Their distribution according to the viremia was as follows: 0 - 1 log = 1 (0.7%) patients;1.5 to 2 log = 23 (16%) patients;2.5 to 3 log = 49 (35%) patients;>3log = 55 (39%) patients. Of the 302 patients included, 36 (11%) patients were treated with antivirals and 253 (83%) patients were not. Conclusion: The number of patients treated for chronic viral hepatitis B was low. Our results show interest for improved preventive and curative management of hepatitis B in Congo in order to reduce the existing high prevalence.展开更多
The study is interested in chemical quality of water of the one of the five aquifers, unconfined water AQ1, (other free groundwaters AQ2, AQ3, AQ4 and AQ5 being captive) in the area of Pointe-Noire. A series of physic...The study is interested in chemical quality of water of the one of the five aquifers, unconfined water AQ1, (other free groundwaters AQ2, AQ3, AQ4 and AQ5 being captive) in the area of Pointe-Noire. A series of physicochemical analysis was carried out on the samples of water of the zone. The results of these analyses were treated starting from a chemical-hydro method which uses the diagrams of Piper, Stabler, Schoeller Berkaloff, Stiff, Wilcox and the statistical methods classic. These chemical-hydro results made it possible to highlight the prevalence of sodic and potassic facies chlorinated in groundwaters of the unconfined water of the area of Pointe-Noire. In this area, the groundwaters of the unconfined water gather in three principal-hydro facies: sodic and potassic chlorinated waters are the most important (66.7%) in the studied water;calcic and magnesian bicarbonated water (16.65%) and bicarbonated sodic and potassic ones (16.65%). This study reveals that the groundwaters of the area of Pointe-Noire undergo an intrusion saltworks. As a whole, these groundwaters require in certain cases, a specific treatment before consumption.展开更多
Rooting ability in Vitis vinifera L. is the phenomena studied. The evolution of the total lipids contents and fatty acids amount of cuttings during the rooting were determined. Total lipid extraction was carried out b...Rooting ability in Vitis vinifera L. is the phenomena studied. The evolution of the total lipids contents and fatty acids amount of cuttings during the rooting were determined. Total lipid extraction was carried out by an extraction solvent consisting of a mixture of chloroform and methanol. Methylation of fatty acids was carried out by the boron trifluoride methanol complex. Their analysis is performed by gas chromatography. We have obtained a content of merithallus lipids equivalent with then in bibliography. In other hand 3 fatty acids were obtained: eicosapentaenoic acid, oleic acid and docosanoic acid. Among the studied of rooting abilities, we observed decreased levels of total lipids and in the essential fatty acids: eicosapentaenoic acid C20:5 n-3 and oleic acid C18:1 n-9. Minor fatty acids cuttings experimental have a variable evolution. Lipids and certain fatty acids may be markers of rooting in the vine.展开更多
Introduction: Breast cancer is the leading cancer and the leading cause of cancer death in women worldwide. About 5% to 10% of breast cancer patients present with metastases. While the 5-year survival of patients with...Introduction: Breast cancer is the leading cancer and the leading cause of cancer death in women worldwide. About 5% to 10% of breast cancer patients present with metastases. While the 5-year survival of patients with local breast cancer varies around 98.8%, this survival rate drops to around 26.3% for metastatic patients. The objective of this study was to determine the survival of patients with metastatic breast cancer in resource-limited settings. Patients and Methods: This was a cross-sectional descriptive study that took place in the Cancer Department of the General Hospital of Loandjili in Pointe Noire during the period from January 1, 2013 to December 31, 2018, for duration of 6 years. 30 records of patients over 18 years of age and with histological evidence who received at least 3 courses of chemotherapy were collected. The variables studied were: age, level of education, socio-economic level, menopausal status, history, WHO status, menopausal status, tumor size, histological type, tumor location, the type of treatment and survival. Survival was calculated by Kaplan Meier method. Fisher’s exact test was used to search for correlation between variables. Results: The average age was 52.62 ± 10.96 years old. The extremes were 33 years and 75 years old. The most represented level of education was the primary level in 67% of cases. The majority of patients had low socioeconomic status in 50% of cases. The patients were menopausal in 57% of cases. The antecedents of cancer were present in 13% of cases. 50% of patients had a WHO status performance at 2. The tumor size was greater than 2 cm in 77% of cases. The most represented histological type was invasive ductal carcinoma in 93% of cases. The most represented histological grade was Scharff grade III Richardson bloom in 80% of cases. The most represented metastatic localization was pulmonary in 33% of cases. The metastatic localizations were unique in 47% of cases and multiple in 53% of cases. Anthracycline-based chemotherapy was more used in 53% of cases. Bivariate analysis revealed a correlation between tumor size and number of metastases, p 0.05. Patients treated with anthracyclines were greater than that of patients treated with taxanes in combination was 26.48 months, p > 0.05. Conclusion: Metastatic breast cancer remains an incurable disease, its survival remains low despite diagnostic and therapeutic advances that remain difficult to access for our resource-poor developing countries. Patients are treated with conventional chemotherapy (anthracyclines and taxanes). The most common metastases are respectively pulmonary, hepatic and cerebral in our context.展开更多
As numerical modeling is an effective tool for managing groundwater resources and predicting future responses, in this study, the author has intended to assess groundwater flow through Modflow 6 and Model Muse into Po...As numerical modeling is an effective tool for managing groundwater resources and predicting future responses, in this study, the author has intended to assess groundwater flow through Modflow 6 and Model Muse into Pointe-Noire coastal aquifers. The results showed that the fourth scenario has the biggest effect on the drawdown and seawater intrusion extent. Different parameters including evapotranspiration, recharge, model boundary, etc. were adjusted to run the model. The fourth scenario with the highest pumping rate value caused a slight increase of head values over the values simulated.展开更多
INTRODUCTION: The objective of our study was to determine the epidemiological clinical and histological aspects of gynecological and breast cancers in Pointe-Noire. PATIENTS AND METHODS: This was a retrospective descr...INTRODUCTION: The objective of our study was to determine the epidemiological clinical and histological aspects of gynecological and breast cancers in Pointe-Noire. PATIENTS AND METHODS: This was a retrospective descriptive study that took place in the cancerology and internal medicine department during the period from January 1, 2012 to December 31, 2021, i.e. a period of 10 years. Women with histological diagnosis of gynecological and breast cancers were included in our study. The variables studied were: frequency, age, alcohol and tobacco consumption, histological type, stage of extension, location of cancer. Bivariate analysis was done between age and location of the tumour. The statistical test used was the KHI2 test. The results were statistically significant for a value of p RESULTS: We collected 400 files from women with cancer. Among the 400 files, 265 were represented by gynecological and breast cancers, that is a frequency of 65.43%. Among the 265 cases of gynecological and breast cancer identified during this study period, breast cancer represented the first rank with 52% frequency. Cervical cancer accounted for 41% followed by ovarian cancer (5%) and endometrial (2%). Cancer of vulva was represented by a single case. The average age of patients with gynecological and breast cancers during our study was 52 ± 12 years. The average age of patients with cancer of the breast, cervix, ovarian, endometrial was respectively 49 ± 11.97 years, 54.73 ± 12.91 years old, 50 ± 14 years, 67 ± 14.24 years, the age of the vulva cancer patient was 51 years old. The histological type of breast cancer was represented by infiltrating ductal adenocarcinoma in 91% of cases, invasive lobular carcinoma in 7% and sarcoma in 2%. Cervical cancers were represented by squamous cell carcinomas in 95% of cases and adenocarcinomas in 5% of cases. Vulva cancer was represented by squamous cell carcinoma, ovarian cancer was represented by epithelial tumors (adenocarcinoma) in 100% of cases. Endometrial cancers were represented by endometrial adenocarcinoma. All cancers were diagnosed at advanced stages (locoregional and metastatic stage). Patients over the age of 50 had more gynecological and breast cancers;but this result was not significant. CONCLUSION: Gynecological and breast cancers are frequent and constitute the first cancer of Congolese women in Pointe-Noire. Breast cancer is the first cancer followed by cancer of the cervix and ovaries. The histological types are those of the literature. Patients with gynecological and breast cancers consult at very advanced stages.展开更多
Current antiretroviral therapy has reduced morbidity and mortality of HIV patients. However, their induced hepatotoxicity constitutes a risk. In this issue, we report a clinical case of fulminant hepatitis, observed i...Current antiretroviral therapy has reduced morbidity and mortality of HIV patients. However, their induced hepatotoxicity constitutes a risk. In this issue, we report a clinical case of fulminant hepatitis, observed in the HIV unit of the hepatogastroenterology department of the General hospital of Loandjili in Pointe-Noire. The patient is a 36-year-old female HIV treated with triple-dug combination antiretroviral therapies (ART) including one antiprotease (ritonavir) and two non-nucleoside reverse transcriptase inhibitors (nevirapine and efavirenz). He developed fulminant hepatitis five years after treatment initiation. He succumbed to the side effects. Although antiretroviral combination therapies are the standard of care for HIV infection, increased vigilance is warranted to early identify this side effect and adjust treatment in order to prevent fatal consequences.展开更多
In the novel What I Saw and How I Lied (2008), Judy Blundell presents readers a world of noir where so many lies are around the innocent protagonist, 15-year-old girl Evie. It is a challenge for Evie to probe into t...In the novel What I Saw and How I Lied (2008), Judy Blundell presents readers a world of noir where so many lies are around the innocent protagonist, 15-year-old girl Evie. It is a challenge for Evie to probe into the heart of the deceptions and make ethical choices between good and evil. After experiencing the path from error to truth, from confusion to clarity, and unconsciousness to consciousness, Evie comes to realize the corruption and evils of the society and in an epiphany, obtains a self-knowledge which leads to her initiation. Through analyzing the ethical predicament and ethical choices of the protagonist Evie as well as the negative living environment around her, the present paper aims to interrogate the moral issues of truth, lie, justice, greed, fidelity, and betrayal so as to give readers a better understanding of the theme of initiation in the novel.展开更多
In order to highlight the contribution of Literature to the study of Domestic Violence,this essay will reflect on the relevance of some Anglo-American literary works,integrated in the Domestic Gothic or Domestic Noir,...In order to highlight the contribution of Literature to the study of Domestic Violence,this essay will reflect on the relevance of some Anglo-American literary works,integrated in the Domestic Gothic or Domestic Noir,a subgenre of the psychological thriller,distinguished by the peculiarity of representing a woman in danger as its main character.The family can be the most commonly considered luminous space of harmony,affection and quiet domesticity,but everything can turn upside down whenever this stereotype is reversed drastically.The so-called domestic noir,a new genre popularized in 2013,deals with these dualities,demonstrating that gothic fiction has always been interested in family conflicts and domestic violence in its most varied forms,turning them into sources of terror so relevant to our time.展开更多
文摘Management of the Pointe-Noire Forest requires high-performance tools for simulating tree and stand growth and assessing the sustainability of plantations. Modelling the dynamics of even-aged and mono-species stands is a very active research topic. The approaches adopted by researchers vary according to the objectives and species considered: dendrometrical, Eco physiological or architectural. Thanks to the particular nature of these plantations and the trial set-up, it will be possible to explore the various aspects of production, clearly separating the part linked to genetics (three clones tested) from the part linked to the environment (via fertilisation) and the part associated with competition between trees (via planting densities and thinning regimes). This study will make a major contribution to the applicability of the self-thinning line and the RDI (Reineke Density Index) (Reineke, 1933) to fast-growing plantations. This research work will contribute to two points: 1) product diversification, which is a way of coping with international variations in timber markets, and 2) understanding how ecosystems function in exceptionally poor conditions, which will then enable the environmental impacts of the various recommended silvicultural itineraries to be assessed. The results obtained show that competition between trees in a stand of eucalyptus at very high density (10,000 stems/ha) and in two environments of very contrasting fertility is different depending on the clone. The decision on the date of the first thinning with a view to silviculture for timber and energy wood, which aims to ensure sustained and sustainable production of eucalyptus wood in these soils, should be taken between 12 and 14 months. The competition band is strong between 14 and 17 months, when the RDI = 0.8 is double that observed at 12 months.
文摘Introduction: Breast cancer is the leading cancer and the leading cause of cancer death in women worldwide. The objective of our study was to describe the epidemiological, clinical and therapeutic aspects of breast cancer at the General Hospital of Loandjili in Pointe Noire. Patients and Methods: This was a descriptive and cross-sectional study that took place in the Cancer Department of the General Hospital of Loandjili in Pointe Noire during the period from January 1st, 2012 to December 31st, 2016 for duration of 5 years. 54 records of patients over 18 years of age with histological evidence were collected. The variables studied were: age, level of education, time to presentation, telltale sign, stage of extension, histological type, and histological grade. Chi-square test was used to compare variables and groups. Results: At the end of this study, we collected 54 files of breast cancer patients from 150 patients hospitalized in the Cancer Department. The frequency of breast cancer was 36%. The average age was 50 ± 13.6 years;the extremes were 27 years and 79 years. The most represented age group was from 37 to 40 years old with a percentage of 28%. The patient’s level of study was primary in the majority of cases (57%). The most represented histological type was invasive ductal carcinoma, (100%). The majority of patients arrived at advanced stages 44.4% and metastatic stages 26%. Patients were treated in most of cases by chemotherapy (82%), surgery (42%) and radiotherapy (10%). There was a correlation between time of presentation and stage of extension. Conclusion: Breast cancer is the first cancer of the woman in Pointe Noire. Patients arrive at advanced stages;the most common histological type is invasive ductal carcinoma. The presentation time is correlated with the extension stage. These results suggest the establishment of a cancer control program in developing countries.
文摘The synthesis of geological and petroleum research undertaken in the coastal Sedimentary Basin of the Pointe-Noire region enabled the establishment of a lithostratigraphic scale. It has been observed that the order in which the series observed in outcrop and those encountered by deep wells succeed each other has allowed a value to be given to this relative scale. The study area corresponds to a longitudinal tectonic accident, fault or flexure. It belongs to the Cretaceous and Tertiary coastal sedimentary basin covered by the Plio-Pleistocene age formations (series of circuses), formed of highly permeable sands comprising multiple resistant horizons that store large bodies of water whose reserves are considered very important. Hydrographic network is composed of four main basins with a mediocre size. The quality of this groundwater is considered to be satisfactory for household consumption, but the sustainable management of these reserves requires constant checks on their quality as well as on the level of the reserves. All these resources put the agglomeration of Pointe-Noire close to large exploitable water reserves that meet the need for drinking water, even if, on the whole, the agglomeration is still experiencing many difficulties in terms of its drinking water supply.
文摘Prevalence of hepatitis B in Pointe-Noire is 23%. The objective of this study was to evaluate the level of therapeutic management of patients with hepatitis B in Pointe-Noire. Methods: A retrospective, cross-sectional, descriptive and analytical study. Results: 302 patients included: 217 (72%) men and 85 (28%) women of median age 40 years. The viral load was measured in 140 (46%) patients and in 162 (54%), the viral load was not measured. Their distribution according to the viremia was as follows: 0 - 1 log = 1 (0.7%) patients;1.5 to 2 log = 23 (16%) patients;2.5 to 3 log = 49 (35%) patients;>3log = 55 (39%) patients. Of the 302 patients included, 36 (11%) patients were treated with antivirals and 253 (83%) patients were not. Conclusion: The number of patients treated for chronic viral hepatitis B was low. Our results show interest for improved preventive and curative management of hepatitis B in Congo in order to reduce the existing high prevalence.
文摘The study is interested in chemical quality of water of the one of the five aquifers, unconfined water AQ1, (other free groundwaters AQ2, AQ3, AQ4 and AQ5 being captive) in the area of Pointe-Noire. A series of physicochemical analysis was carried out on the samples of water of the zone. The results of these analyses were treated starting from a chemical-hydro method which uses the diagrams of Piper, Stabler, Schoeller Berkaloff, Stiff, Wilcox and the statistical methods classic. These chemical-hydro results made it possible to highlight the prevalence of sodic and potassic facies chlorinated in groundwaters of the unconfined water of the area of Pointe-Noire. In this area, the groundwaters of the unconfined water gather in three principal-hydro facies: sodic and potassic chlorinated waters are the most important (66.7%) in the studied water;calcic and magnesian bicarbonated water (16.65%) and bicarbonated sodic and potassic ones (16.65%). This study reveals that the groundwaters of the area of Pointe-Noire undergo an intrusion saltworks. As a whole, these groundwaters require in certain cases, a specific treatment before consumption.
文摘Rooting ability in Vitis vinifera L. is the phenomena studied. The evolution of the total lipids contents and fatty acids amount of cuttings during the rooting were determined. Total lipid extraction was carried out by an extraction solvent consisting of a mixture of chloroform and methanol. Methylation of fatty acids was carried out by the boron trifluoride methanol complex. Their analysis is performed by gas chromatography. We have obtained a content of merithallus lipids equivalent with then in bibliography. In other hand 3 fatty acids were obtained: eicosapentaenoic acid, oleic acid and docosanoic acid. Among the studied of rooting abilities, we observed decreased levels of total lipids and in the essential fatty acids: eicosapentaenoic acid C20:5 n-3 and oleic acid C18:1 n-9. Minor fatty acids cuttings experimental have a variable evolution. Lipids and certain fatty acids may be markers of rooting in the vine.
文摘Introduction: Breast cancer is the leading cancer and the leading cause of cancer death in women worldwide. About 5% to 10% of breast cancer patients present with metastases. While the 5-year survival of patients with local breast cancer varies around 98.8%, this survival rate drops to around 26.3% for metastatic patients. The objective of this study was to determine the survival of patients with metastatic breast cancer in resource-limited settings. Patients and Methods: This was a cross-sectional descriptive study that took place in the Cancer Department of the General Hospital of Loandjili in Pointe Noire during the period from January 1, 2013 to December 31, 2018, for duration of 6 years. 30 records of patients over 18 years of age and with histological evidence who received at least 3 courses of chemotherapy were collected. The variables studied were: age, level of education, socio-economic level, menopausal status, history, WHO status, menopausal status, tumor size, histological type, tumor location, the type of treatment and survival. Survival was calculated by Kaplan Meier method. Fisher’s exact test was used to search for correlation between variables. Results: The average age was 52.62 ± 10.96 years old. The extremes were 33 years and 75 years old. The most represented level of education was the primary level in 67% of cases. The majority of patients had low socioeconomic status in 50% of cases. The patients were menopausal in 57% of cases. The antecedents of cancer were present in 13% of cases. 50% of patients had a WHO status performance at 2. The tumor size was greater than 2 cm in 77% of cases. The most represented histological type was invasive ductal carcinoma in 93% of cases. The most represented histological grade was Scharff grade III Richardson bloom in 80% of cases. The most represented metastatic localization was pulmonary in 33% of cases. The metastatic localizations were unique in 47% of cases and multiple in 53% of cases. Anthracycline-based chemotherapy was more used in 53% of cases. Bivariate analysis revealed a correlation between tumor size and number of metastases, p 0.05. Patients treated with anthracyclines were greater than that of patients treated with taxanes in combination was 26.48 months, p > 0.05. Conclusion: Metastatic breast cancer remains an incurable disease, its survival remains low despite diagnostic and therapeutic advances that remain difficult to access for our resource-poor developing countries. Patients are treated with conventional chemotherapy (anthracyclines and taxanes). The most common metastases are respectively pulmonary, hepatic and cerebral in our context.
文摘As numerical modeling is an effective tool for managing groundwater resources and predicting future responses, in this study, the author has intended to assess groundwater flow through Modflow 6 and Model Muse into Pointe-Noire coastal aquifers. The results showed that the fourth scenario has the biggest effect on the drawdown and seawater intrusion extent. Different parameters including evapotranspiration, recharge, model boundary, etc. were adjusted to run the model. The fourth scenario with the highest pumping rate value caused a slight increase of head values over the values simulated.
文摘INTRODUCTION: The objective of our study was to determine the epidemiological clinical and histological aspects of gynecological and breast cancers in Pointe-Noire. PATIENTS AND METHODS: This was a retrospective descriptive study that took place in the cancerology and internal medicine department during the period from January 1, 2012 to December 31, 2021, i.e. a period of 10 years. Women with histological diagnosis of gynecological and breast cancers were included in our study. The variables studied were: frequency, age, alcohol and tobacco consumption, histological type, stage of extension, location of cancer. Bivariate analysis was done between age and location of the tumour. The statistical test used was the KHI2 test. The results were statistically significant for a value of p RESULTS: We collected 400 files from women with cancer. Among the 400 files, 265 were represented by gynecological and breast cancers, that is a frequency of 65.43%. Among the 265 cases of gynecological and breast cancer identified during this study period, breast cancer represented the first rank with 52% frequency. Cervical cancer accounted for 41% followed by ovarian cancer (5%) and endometrial (2%). Cancer of vulva was represented by a single case. The average age of patients with gynecological and breast cancers during our study was 52 ± 12 years. The average age of patients with cancer of the breast, cervix, ovarian, endometrial was respectively 49 ± 11.97 years, 54.73 ± 12.91 years old, 50 ± 14 years, 67 ± 14.24 years, the age of the vulva cancer patient was 51 years old. The histological type of breast cancer was represented by infiltrating ductal adenocarcinoma in 91% of cases, invasive lobular carcinoma in 7% and sarcoma in 2%. Cervical cancers were represented by squamous cell carcinomas in 95% of cases and adenocarcinomas in 5% of cases. Vulva cancer was represented by squamous cell carcinoma, ovarian cancer was represented by epithelial tumors (adenocarcinoma) in 100% of cases. Endometrial cancers were represented by endometrial adenocarcinoma. All cancers were diagnosed at advanced stages (locoregional and metastatic stage). Patients over the age of 50 had more gynecological and breast cancers;but this result was not significant. CONCLUSION: Gynecological and breast cancers are frequent and constitute the first cancer of Congolese women in Pointe-Noire. Breast cancer is the first cancer followed by cancer of the cervix and ovaries. The histological types are those of the literature. Patients with gynecological and breast cancers consult at very advanced stages.
文摘Current antiretroviral therapy has reduced morbidity and mortality of HIV patients. However, their induced hepatotoxicity constitutes a risk. In this issue, we report a clinical case of fulminant hepatitis, observed in the HIV unit of the hepatogastroenterology department of the General hospital of Loandjili in Pointe-Noire. The patient is a 36-year-old female HIV treated with triple-dug combination antiretroviral therapies (ART) including one antiprotease (ritonavir) and two non-nucleoside reverse transcriptase inhibitors (nevirapine and efavirenz). He developed fulminant hepatitis five years after treatment initiation. He succumbed to the side effects. Although antiretroviral combination therapies are the standard of care for HIV infection, increased vigilance is warranted to early identify this side effect and adjust treatment in order to prevent fatal consequences.
文摘In the novel What I Saw and How I Lied (2008), Judy Blundell presents readers a world of noir where so many lies are around the innocent protagonist, 15-year-old girl Evie. It is a challenge for Evie to probe into the heart of the deceptions and make ethical choices between good and evil. After experiencing the path from error to truth, from confusion to clarity, and unconsciousness to consciousness, Evie comes to realize the corruption and evils of the society and in an epiphany, obtains a self-knowledge which leads to her initiation. Through analyzing the ethical predicament and ethical choices of the protagonist Evie as well as the negative living environment around her, the present paper aims to interrogate the moral issues of truth, lie, justice, greed, fidelity, and betrayal so as to give readers a better understanding of the theme of initiation in the novel.
文摘In order to highlight the contribution of Literature to the study of Domestic Violence,this essay will reflect on the relevance of some Anglo-American literary works,integrated in the Domestic Gothic or Domestic Noir,a subgenre of the psychological thriller,distinguished by the peculiarity of representing a woman in danger as its main character.The family can be the most commonly considered luminous space of harmony,affection and quiet domesticity,but everything can turn upside down whenever this stereotype is reversed drastically.The so-called domestic noir,a new genre popularized in 2013,deals with these dualities,demonstrating that gothic fiction has always been interested in family conflicts and domestic violence in its most varied forms,turning them into sources of terror so relevant to our time.