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The Effect of a High-Frequency-Hearing-Threshold Weighted Value on the Diagnosis of Occupational-Noise-Induced Deafness 被引量:1
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作者 Laijun Xue Yanhong Zhang Aichu Yang 《Journal of Biosciences and Medicines》 2018年第12期88-99,共12页
Objective: In order to provide a theoretical basis for the revision of the current diagnostic criteria for occupational noise-induced deafness (ONID), we evaluated the degree of ONID by analyzing different high-freque... Objective: In order to provide a theoretical basis for the revision of the current diagnostic criteria for occupational noise-induced deafness (ONID), we evaluated the degree of ONID by analyzing different high-frequency-hearing- threshold-weighted values (HFTWVs). Methods: A retrospective study was conducted to evaluate the diagnosis of patients with ONID from January 2016 to January 2017 in Guangdong province, China. Based on 3 hearing tests (each interval between the tests was greater than 3 days), the minimum threshold value of each frequency was obtained using the 2007 edition’s diagnostic criteria for ONID. The speech frequency and the HFTWVs were analyzed based on age, noise exposure, and diagnostic classi-fication using SPSS21.0. Results: 168 patients in total were involved in this study, 154 males and 14 females, and the average age was 41.18 ± 6.07. The diagnosis rate was increased by the weighted value of the high frequencies and was more than the mean value of the pure speech frequency (MVPSF). The diagnosis rate for the weighted 4 kHz frequency level increased by 13.69% (χ2 = 9.880, P = 0.002), the weighted 6 kHz level increased by 15.47% (χ2 = 9.985, P = 0.002), and the weighted 4 kHz + 6 kHz level increased by 15.47% (χ2 = 9.985, P = 0.002). The differences were all statistically significant. The diagnostic rate of the different thresholds showed no obvious difference between the genders. The age groups were divided into less than or equal to 40 years old (group A) and 40 - 50 years old (group B). There were several groups with a high frequency: high frequency weighted 4 kHz ( group A χ2 = 3.380, P = 0.050;group B χ2 = 4.054, P = 0.032), high frequency weighted 6 kHz (group A χ2 = 6.362, P = 0.012;group B χ2 = 4.054, P = 0.032), weighted 4 kHz + 6 kHz (group A χ2 = 6.362 P = 0.012;B χ2 = 4.054, P = 0.032) than those of MVPSF in the same group on ONID diagnosis rate. The differences between the groups were statistically significant. There was no significant difference between the age groups (χ2 = 2.265, P = 0.944). The better ear’s (the smaller hearing threshold weighted value) MVPSF and the weighted values for the different high frequencies were examined in light of the number of working years;the group that was exposed to noise for more than 10 years had significantly higher values than those of the average thresholds of each frequency band in the groups with 3 - 5 years of exposure (F = 2.271, P = 0.001) and 6 - 10 years of exposure (F = 1.563, P = 0.046). The differences were statistically significant. The different HFTWVs were higher than those of the MVPSF values, and the high frequency weighted 4 kHz + 6 kHz level showed the greatest difference, with an average increase of 2.83 dB. The diagnostic rate that included the weighted high frequency values was higher for the mild, moderate, and severe cases than those patients who were only screened with the pure frequency tests. The results of the comparisons of the diagnosis rates for mild ONID were as follows: the weighted 3 kHz high frequency level (χ2 = 3.117, P = 0.077) had no significant difference, but the weighted 4 kHz level (χ2 = 10.835, P = 0.001), 6 kHz level (χ2 = 9.985, P = 0.002), 3 kHz + 4 kHz level (χ2 = 6.315, P = 0.012), 3 kHz + 6 kHz level (χ2 = 6.315, P = 0.012), 4 kHz + 6 kHz level (χ2 = 9.985, P = 0.002), and 3 kHz + 4 kHz + 6 kHz level (χ2 = 7.667, P = 0.002) were significantly higher than the diagnosis rate of the mean value of the PSF. There was no significant difference between the 2 groups for the moderate and severe grades (P > 0.05). Conclusion: Different HFTWVs increase the diagnostic rate of ONID. The weighted 4 kHz, 6 kHz, and 4 kHz + 6 kHz high frequency values greatly affected the diagnostic results, and the weighted 4 kHz + 6 kHz high frequency hearing threshold value has the maximum the effect on the ONID diagnosis results. 展开更多
关键词 Noise OCCUPATIONAL Noise deafness noise-induced HEARING Loss High Fre-quency HEARING THRESHOLD WEIGHTED Value Diagnostic Rate
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基于静息态功能磁共振成像的噪声聋全脑因果功能连接分析
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作者 王爱杰 黄冉冉 +3 位作者 王春业 巴新茹 包相华 张国伟 《中华劳动卫生职业病杂志》 CAS CSCD 北大核心 2024年第9期689-694,共6页
目的采用度中心度(DC)及格兰杰因果分析(GCA)综合研究噪声聋(NID)患者听觉中枢及非听觉中枢定向连接的改变,探索噪声聋后的脑功能重塑模式。方法于2023年10月,选择2014至2022年经烟台市烟台山医院职业病科确诊为NID的患者58例为病例组(... 目的采用度中心度(DC)及格兰杰因果分析(GCA)综合研究噪声聋(NID)患者听觉中枢及非听觉中枢定向连接的改变,探索噪声聋后的脑功能重塑模式。方法于2023年10月,选择2014至2022年经烟台市烟台山医院职业病科确诊为NID的患者58例为病例组(NID组),选取性别、年龄、受教育程度相匹配的健康志愿者42例为对照组(HC组),行静息态脑功能磁共振成像(Rs-fMRI)并进行DC分析,根据结果选取组间DC值有统计学差异的脑区、双侧Heschl区为感兴趣区(ROI),进行基于体素的全脑GCA及相关分析。结果与HC组比较,NID组左侧枕上回(SOG.L)DC值减低,左背侧额上回(SFGdor.L)到SOG.L的连接增高,左中央旁小叶(PCL.L)到SOG.L的连接减低;左眶部额中回(ORBmid.L)、右后扣带回(PCG.R)、双侧楔叶(CUN.L/R)到左侧颞横回(HES.L)连接增高,SFGdor.L到HES.L连接减低,HES.L到左楔前叶(PCUN.L)连接减低;左眶部额上回(ORBsup.L)、PCG.R到右侧颞横回(HES.R)连接增高,HES.R到CUN.L连接减低(P voxel level<0.01,P cluster level<0.05)。NID组PCL.L到SOG.L连接值与较好耳语频听阈加权值呈负相关(P<0.05)。结论NID患者听视觉、执行控制及体感运动、默认网络等多个脑区定向连接活动异常,提示听觉损失可造成听觉中枢及非听觉中枢之间发生复杂的脑功能网络神经重塑改变。 展开更多
关键词 耳聋 噪声聋 磁共振成像 大脑 度中心度 格兰杰因果分析 因果连接
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