Corneal ulcers,especially of fungal origin,are a relatively common clinical entity within the spectrum of keratitis in tropical countries.The persistence of a non-healing epithelial defect is a known complication of t...Corneal ulcers,especially of fungal origin,are a relatively common clinical entity within the spectrum of keratitis in tropical countries.The persistence of a non-healing epithelial defect is a known complication of these ulcers.Despite advances in medical therapy,the management of this condition is still challenging.CACICOL20^(®)is a new ophthalmic matrix therapy that has been proved efficient as a corneal healing agent.To the best of our knowledge there have been reports of the limited use of matrix therapy in ocular healing,specifically in fungal keratitis.We report 2 cases of the efficacy of it as an adjuvant to topical amphotericin B in treating non-healing epithelial defects secondary to fungal corneal ulcers.展开更多
基金Supported by Universiti Sains Malaysia Study Grant(Grant No.304/PPSP/6139048).
文摘Corneal ulcers,especially of fungal origin,are a relatively common clinical entity within the spectrum of keratitis in tropical countries.The persistence of a non-healing epithelial defect is a known complication of these ulcers.Despite advances in medical therapy,the management of this condition is still challenging.CACICOL20^(®)is a new ophthalmic matrix therapy that has been proved efficient as a corneal healing agent.To the best of our knowledge there have been reports of the limited use of matrix therapy in ocular healing,specifically in fungal keratitis.We report 2 cases of the efficacy of it as an adjuvant to topical amphotericin B in treating non-healing epithelial defects secondary to fungal corneal ulcers.
