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基于改进Conformer的新闻领域端到端语音识别 被引量:2
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作者 张济民 早克热·卡德尔 +2 位作者 艾山·吾买尔 申云飞 汪烈军 《中文信息学报》 CSCD 北大核心 2024年第4期156-164,共9页
目前,开源的中文语音识别数据集大多面向通用领域,缺少面向新闻领域的开源语音识别语料库,因此该文构建了面向新闻领域的中文语音识别数据集CH_NEWS_ASR,并使用ESPNET-0.9.6框架的RNN、Transformer和Conformer等模型对数据集的有效性进... 目前,开源的中文语音识别数据集大多面向通用领域,缺少面向新闻领域的开源语音识别语料库,因此该文构建了面向新闻领域的中文语音识别数据集CH_NEWS_ASR,并使用ESPNET-0.9.6框架的RNN、Transformer和Conformer等模型对数据集的有效性进行了验证,实验表明,该文所构建的语料在最好的模型上CER为4.8%,SER为39.4%。由于新闻联播主持人说话语速相对较快,该文构建的数据集文本平均长度为28个字符,是Aishell_1数据集文本平均长度的2倍;且以往的研究中训练目标函数通常为基于字或词水平,缺乏明确的句子水平关系,因此该文提出了一个句子层级的一致性模块,与Conformer模型结合,直接减少源语音和目标文本的表示差异,在开源的Aishell_1数据集上其CER降低0.4%,SER降低2%;在CH_NEWS_ASR数据集上其CER降低0.9%,SER降低3%,实验结果表明,该方法在不增加模型参数量的前提下能有效提升语音识别的质量。 展开更多
关键词 端到端语音识别 conformER 句子层级一致性
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Conformal invariance and conserved quantities of non-conservative Lagrange systems by point transformations 被引量:3
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作者 刘畅 梅凤翔 郭永新 《Chinese Physics B》 SCIE EI CAS CSCD 2009年第2期395-399,共5页
This paper studies the conformal invariance by infinitesimal point transformations of non-conservative Lagrange systems. It gives the necessary and sufficient conditions of conformal invariance by the action of infini... This paper studies the conformal invariance by infinitesimal point transformations of non-conservative Lagrange systems. It gives the necessary and sufficient conditions of conformal invariance by the action of infinitesimal point transformations being Lie symmetric simultaneously. Then the Noether conserved quantities of conformal invariance are obtained. Finally an illustrative example is given to verify the results. 展开更多
关键词 non-conservative Lagrange systems point transformations conformal invariance conserved quantities
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Non-thermal effects of 0.1 THz radiation on intestinal alkaline phosphatase activity and conformation 被引量:2
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作者 Xin-Xin Zhang Ming-Xia He +4 位作者 Yu Chen Cheng Li Jin-Wu Zhao Peng-Fei Wang Xin Peng 《Chinese Physics B》 SCIE EI CAS CSCD 2019年第12期383-388,共6页
Alkaline phosphatase(ALP) plays an integral role in the metabolism of liver and development of the skeleton in humans. To date, the interactions between different-duration terahertz(THz) radiation and ALP activities, ... Alkaline phosphatase(ALP) plays an integral role in the metabolism of liver and development of the skeleton in humans. To date, the interactions between different-duration terahertz(THz) radiation and ALP activities, as well as the influence mechanism are still unclear. In this study, using the para-nitro-phenyl-phosphate(p NPP) method, we detect changes in ALP activities during 40-minute THz radiation(0.1 THz, 13 m W/cm^2). It is found that the activity of ALP decreases in the first 25 min, and subsequently increases in the later 15 min. Compared with the activity of ALP being heated, the results suggest that short-term terahertz radiation induces a decrease in enzyme activity through the non-thermal mechanism. In order to explore the non-thermal effects of THz radiation on ALP, we focus on the impacts of 0.1 THz radiation for 20 min on the activity of ALP in different concentrations. The results reveal that the activity of ALP decreases significantly after exposure to THz radiation. In addition, it could be deduced from fluorescence, ultraviolet-visible(UV-vis), and THz spectra results that THz radiation has induced changes in ALP structures. Our study unlocks non-thermal interactions between THz radiation and ALP, as well as suggests that THz spectroscopy is a promising technique to distinguish ALP structures. 展开更多
关键词 THz radiation alkaline phosphatase non-thermal effects SPECTROSCOPY conformATIONS
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Non-Noether symmetries of Hamiltonian systems with conformable fractional derivatives 被引量:3
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作者 王琳莉 傅景礼 《Chinese Physics B》 SCIE EI CAS CSCD 2016年第1期647-652,共6页
In this paper, we present the fractional Hamilton's canonical equations and the fractional non-Noether symmetry of Hamilton systems by the conformable fractional derivative. First/y, the exchanging relationship betwe... In this paper, we present the fractional Hamilton's canonical equations and the fractional non-Noether symmetry of Hamilton systems by the conformable fractional derivative. First/y, the exchanging relationship between isochronous variation and fractional derivatives, and the fractional Hamilton principle of the system under this fractional derivative are proposed. Secondly, the fractional Hamilton's canonical equations of Hamilton systems based on the Hamilton principle are established. Thirdly, the fractional non-Noether symmetries, non-Noether theorem and non-Noether conserved quantities for the Hamilton systems with the conformable fractional derivatives are obtained. Finally, an example is given to illustrate the results. 展开更多
关键词 conformable fractional derivative Hamilton's canonical equation non-Noether conserved quantity
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Conformal invariance and conserved quantity of third-order Lagrange equations for non-conserved mechanical systems 被引量:2
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作者 张明江 方建会 +2 位作者 路凯 张克军 李燕 《Chinese Physics B》 SCIE EI CAS CSCD 2009年第11期4650-4656,共7页
This paper studies conformal invariance and conserved quantity of third-order Lagrange equations for non- conserved mechanical systems. Third-order Lagrange equations, the definition and a determining equation of conf... This paper studies conformal invariance and conserved quantity of third-order Lagrange equations for non- conserved mechanical systems. Third-order Lagrange equations, the definition and a determining equation of conformal invariance of the system are presented. The conformal factor expression is deduced from conformal invariance and Lie symmetry. The necessary and sufficient condition that conformal invaxiance of the system would have Lie symmetry under single-parameter infinitesimal transformations is obtained. The corresponding conserved quantity of conformal invariance is derived with the aid of a structure equation. Lastly, an example is given to illustrate the application of the results. 展开更多
关键词 conformal invariance conserved quantity third-order Lagrange equation non-conserved mechanical system
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基于Conformer的端到端语音识别方法 被引量:1
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作者 胡从刚 申艺翔 +1 位作者 孙永奇 赵思聪 《计算机应用研究》 CSCD 北大核心 2024年第7期2018-2024,共7页
针对Conformer编码器的声学输入网络对FBank语音信息提取不足和通道特征信息缺失问题,提出一种RepVGG-SE-Conformer的端到端语音识别方法。首先,利用RepVGG的多分支结构,增强模型的语音信息提取能力,而在模型推理时通过结构重参数化将... 针对Conformer编码器的声学输入网络对FBank语音信息提取不足和通道特征信息缺失问题,提出一种RepVGG-SE-Conformer的端到端语音识别方法。首先,利用RepVGG的多分支结构,增强模型的语音信息提取能力,而在模型推理时通过结构重参数化将多分支融合为单分支,以降低计算复杂度、加快模型推理速度。然后,利用基于压缩和激励网络的通道注意力机制弥补缺失的通道特征信息,以提高语音识别准确率。最后,在公开数据集Aishell-1上的实验结果表明:相较于Conformer,所提出方法的字错误率降低了10.67%,验证了方法的先进性。此外,RepVGG-SE声学输入网络能够有效提高多种Transformer变体的端到端语音识别模型的整体性能,具有很好的泛化能力。 展开更多
关键词 语音识别 conformER RepVGG 压缩和激励网络
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Water shutoff and conformance improvement: an introduction 被引量:7
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作者 Randy Seright Bergit Brattekas 《Petroleum Science》 SCIE CAS CSCD 2021年第2期450-478,共29页
This paper provides an introduction to the topic of water shutoff and conformance improvement. After indicating the volumes of water produced during oilfield operations, a strategy is provided for attacking excess wat... This paper provides an introduction to the topic of water shutoff and conformance improvement. After indicating the volumes of water produced during oilfield operations, a strategy is provided for attacking excess water production problems. Problem types are categorized, typical methods of problem diagnosis are mentioned, and the range of solutions is introduced for each problem type. In the third section of the paper, the concept of disproportionate permeability reduction is introduced—where polymers and gels may reduce permeability to water more than to oil or gas. When and where this property is of value is discussed. The fourth section describes the properties of formed gels as they extrude through fractures and how those properties can be of value when treating conformance problems caused by fractures. Section 5 covers the efficiency with which gels block fractures after gel placement—especially, the impact of fluids injected subsequent to the gel treatment. 展开更多
关键词 Water shutoff conformance improvement Reservoir sweep improvement
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High-strength and self-degradable sodium alginate/polyacrylamide preformed particle gels for conformance control to enhance oil recovery 被引量:6
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作者 Xiao Zhang Jia-Nan Deng +11 位作者 Kai Yang Qian Li Sen-Yao Meng Xiu-Xia Sun Zhao-Zheng Song Yong-Dong Tian Sui-An Zhang Xin-Jia Liu Zhan-Yi Wang Xin-Yu Liu Gui-Wu Lu Zi-Long Liu 《Petroleum Science》 SCIE CAS CSCD 2022年第6期3149-3158,共10页
Excess water production has become an important issue in the oil and gas extraction process.Preformed particle gels(PPGs),show the capability to control the conformance and reduce excess water cut.However,conventional... Excess water production has become an important issue in the oil and gas extraction process.Preformed particle gels(PPGs),show the capability to control the conformance and reduce excess water cut.However,conventional PPGs have poor mechanical properties and their swollen particles are easily damaged by shearing force when passing through the fractures in formations,meanwhile PPGs can be also degraded into various byproducts,leading to permanent damage to the reservoir permeability after temporary plugging.Herein,a novel type of dual cross-linked PPGs(dPPGs)was designed and synthesized using sodium alginate(SA)and acrylamide(AAm),cross-linked with N,N’-methylenebisacrylamide(MBA)and Fe^(3+).Results show that dPPGs have excellent mechanical properties with a storage modulus up to 86,445 Pa,which is almost 20 times higher than other reported PPGs.Meanwhile,dPPGs can be completely degraded into liquid without any solid residues or byproducts and the viscosity of dPPGs degraded liquid was found to be lower than 5 mPa·s.A laboratory coreflooding test showed that the plugging efficiency of dPPGs was up to 99.83%on open fractures.The obtained results demonstrated that dPPGs could be used as economical and environment-friendly temporary plugging agent with high-strength,self-degradation,thermal stability,and salt stability,thus making it applicable to a wide range of conformance control to enhance oil recovery. 展开更多
关键词 conformance control Sodium alginate Dual cross-linked Temporary plugging agent HIGH-STRENGTH Self-degradation
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Conformance control by a microgel in a multi-layered heterogeneous reservoir during CO_(2) enhanced oil recovery process 被引量:2
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作者 Zheyu Liu Jian Zhang +6 位作者 Xianjie Li Chunming Xu Xin Chen Bo Zhang Guang Zhao Han Zhang Yiqiang Li 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2022年第3期324-334,共11页
Injecting CO_(2)into the underground for oil displacement and shortage is an important technique for carbon capture,utilization and storage(CCUS).One of the main problems during the CO_(2)injection is the channeling p... Injecting CO_(2)into the underground for oil displacement and shortage is an important technique for carbon capture,utilization and storage(CCUS).One of the main problems during the CO_(2)injection is the channeling plugging.Finding an effective method for the gas channeling plugging is a critical issue in the CO_(2)EOR process.In this work,an acid-resistance microgel named dispersed particle gel(DPG)was characterized and its stability was tested in the CO_(2)environment.The microgel size selection strategies for the homogeneous and heterogeneous reservoirs were respectively investigated using the single core flooding and three parallel core flooding experiments.Moreover,the comparison of microgel alternate CO_(2)(MAC)injection and water alternate CO_(2)(WAC)injection in the dual core flooding experiments were presented for the investigation of the role of microgel on the conformance control in CO_(2)flooding process.The results have shown that the microgel featured with ANH and CAN groups can keep its morphology after aging 7 days in the CO_(2)environment.Where,the small microgel with unobstructed migration and large microgel with good plugging efficiency for the high permeability zone were respectively featured with the higher recovery factor in homogeneous and heterogeneous conditions,which indicate they are preferred used for the oil displacement and conformance control.Compared to WAC injection,MAC injection had a higher incremental recovery factor of 12.4%.It suggests the acid-resistance microgel would be a good candidate for the conformance control during CO_(2)flooding process. 展开更多
关键词 Carbon dioxide Microgels Enhanced oil recovery conformance control Porous media
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Clinical observation of gemcitabine and concomitant three-dimensional conformal radiotherapy in the treatment of locally advanced non-small cell lung cancer 被引量:4
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作者 Jing Cheng Gang Wu Hongge Wu Jun Xue 《The Chinese-German Journal of Clinical Oncology》 CAS 2008年第6期311-314,共4页
Objective: To evaluate the clinical effect of gemcitabine and concurrent three-dimensional conformal radiation therapy (3D-CRT) for locally advanced non-small cell lung cancer (NSCLC). Methods: From April 2002 t... Objective: To evaluate the clinical effect of gemcitabine and concurrent three-dimensional conformal radiation therapy (3D-CRT) for locally advanced non-small cell lung cancer (NSCLC). Methods: From April 2002 to June 2005, 38 patients with inoperable stage Ⅲ NSCLC were treated with gemcitabine and 3D-CRT simultaneously. Chemotherapy consisted of intravenously gemcitabine 350 mg/m^2 on days 1, 8, 15, 22, 29, 36.3D-CRT was delivered up to a total dose of 60-64 Gy with a 2.0 Gy dose fraction per day, 5 days per week. Results: The overall response rates of primary tumor and mediastinum metastatic node were 86.8% (33/38) and 90.6% (29/32) respectively, and 91.7% (22/24) and 78.6% (11/14) for squamous cell carcinoma and adenocarcinoma respectively. The acute side effects of patients were mostly myelosuppression, nausea, vomiting, radiation-induced esophagitis and pneumonitis (RTOG 1/11), however, all of them were cured. Conclusion: Concurrent application of gemcitabine and 3D-CRT can improve the overall response rate for locally advanced NSCLC without aggravating the side effects. 展开更多
关键词 non-small cell lung cancer three-dimensional conformal radiation therapy CHEMOTHERAPY concurrent chemoradiotherapy GEMCITABINE
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基于层次化Conformer的语音合成
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作者 吴克伟 韩超 +2 位作者 孙永宣 彭梦昊 谢昭 《计算机科学》 CSCD 北大核心 2024年第2期161-171,共11页
语音合成需要将输入语句的文本转换为包含音素、单词和语句的语音信号。现有语音合成方法将语句看作一个整体,难以准确地合成出不同长度的语音信号。通过分析语音信号中蕴含的层次化关系,分别设计基于Conformer的层次化文本编码器和基于... 语音合成需要将输入语句的文本转换为包含音素、单词和语句的语音信号。现有语音合成方法将语句看作一个整体,难以准确地合成出不同长度的语音信号。通过分析语音信号中蕴含的层次化关系,分别设计基于Conformer的层次化文本编码器和基于Conformer的层次化语音编码器,并提出了一种基于层次化文本-语音Conformer的语音合成模型。首先,该模型根据输入文本信号的长度,构建层次化文本编码器,包括音素级、单词级、语句级文本编码器3个层次,不同层次的文本编码器描述不同长度的文本信息;并使用Conformer的注意力机制来学习该长度信号中不同时间特征之间的关系。利用层次化的文本编码器,能够找出语句中不同长度需要强调的信息,有效实现不同长度的文本特征提取,缓解合成的语音信号持续时间长度不确定的问题。其次,层次化语音编码器包括音素级、单词级、语句级语音编码器3个层次。每个层次的语音编码器将文本特征作为Conformer的查询向量,将语音特征作为Conformer的关键字向量和值向量,来提取文本特征和语音特征的匹配关系。利用层次化的语音编码器和文本语音匹配关系,可以缓解不同长度语音信号合成不准确的问题。所提模型的层次化文本-语音编码器可以灵活地嵌入现有的多种解码器中,通过文本和语音之间的互补,提供更为可靠的语音合成结果。在LJSpeech和LibriTTS两个数据集上进行实验验证,实验结果表明,所提方法的梅尔倒谱失真小于现有语音合成方法。 展开更多
关键词 语音合成 文本编码器 语音编码器 层次化模型 conformER
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A review of nuclear magnetic resonance(NMR) technology applied in the characterization of polymer gels for petroleum reservoir conformance control 被引量:1
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作者 Dao-Yi Zhu Zhi-Hua Deng Si-Wei Chen 《Petroleum Science》 SCIE CAS CSCD 2021年第6期1760-1775,共16页
Polymer gel systems have been widely applied to control excessive water and improve oil recovery(IOR)in petroleum reservoirs.They are usually divided into two main types,in-situ cross-linked polymer gels,and pre-forme... Polymer gel systems have been widely applied to control excessive water and improve oil recovery(IOR)in petroleum reservoirs.They are usually divided into two main types,in-situ cross-linked polymer gels,and pre-formed polymer gels.In recent years,nuclear magnetic resonance(NMR) technology has been gradually applied to the research of polymer gel systems due to its unique analysis advantages.This paper is intent to review these works systematically.For in-situ cross-linked polymer gel systems,NMR can be used to characterize the chemical structure changes of the polymer,the cross-linker,and the auxiliary agent in the formulation of the polymer gel systems.Moreover,the gelation time and the gel strength of the in-situ cross-linked polymer gel systems can also be measured by NMR.For pre-formed polymer gels,NMR can be employed to detect the chemical structure of the designed products.Last,the NMR method can evaluate the plugging,water control,and oil improvement performance of the polymer gels in porous media without using dopants.This review can help readers build a more systematic understanding of the application of NMR technology in polymer gel systems for IOR and help re searchers to more deeply study the performance of polymer gel systems. 展开更多
关键词 Nuclear magnetic resonance Polymer gels Gelation time Gel strength conformance control
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基于Conformer的端到端中英文管制语音识别
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作者 孔建国 韩琪聪 +1 位作者 梁海军 李煜琨 《航空计算技术》 2024年第3期1-5,共5页
将语音识别技术应用到空中交通管理系统中可以提高飞行安全并降低管制员的工作负荷,目前已有的管制语音识别技术在中英文识别上效果较差,因此提出了一种基于Conformer-CTC/Attention的中英文管制语音识别框架。该方法使用基于改进的Conf... 将语音识别技术应用到空中交通管理系统中可以提高飞行安全并降低管制员的工作负荷,目前已有的管制语音识别技术在中英文识别上效果较差,因此提出了一种基于Conformer-CTC/Attention的中英文管制语音识别框架。该方法使用基于改进的Conformer共享编码器对输入序列进行语言分类并以参数有效的方式对音频序列的局部和全局相依性进行建模,添加了语种分类模块来判断输入语音序列的语种,还采用了CTC解码器和注意力解码器联合解码的多任务建模方法。最后在建立的民航数据集对所提出的框架进行验证,试验结果表明,Conformer-CTC/Attention(Language-Category)相对于基线模型错误率降低,识别效果达到预期。 展开更多
关键词 空中交通管制 中英文语音识别 conformer-CTC/Attention 多任务学习 端到端
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Development of a Model Driven ACSI Conformance Testing for IEC 61850-Based IED 被引量:1
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作者 Byungtae Jang Alidu Abubakari Namdae Kim 《Smart Grid and Renewable Energy》 2018年第10期215-236,共22页
Globally, traditional power systems are rapidly transforming towards the adoption of smart grid platforms. Substations which are at the center of the electric power transformation from the power plant are changing to ... Globally, traditional power systems are rapidly transforming towards the adoption of smart grid platforms. Substations which are at the center of the electric power transformation from the power plant are changing to IEC 61850 based digital substations. Therefore, within substation, there is a growing demand for the IEC 61850 based Intelligent Electronic Devices (IEDs). The operation of multiple manufacturers of IEDs in a single digital substation network increases the need for IEC 61850 communications specification conformance diagnosis to ensure interoperability for efficient data exchange between IEDs. The IEC 61850-10 presents test items for diagnosing communication specification conformance. There are many test tools available in the market today to test the compliance of the IEC 61850 communications specifications to the IED. In this paper, we propose a model-based diagnostic method for IED communication conformance testing. The proposed model-based software therefore uses the “drag and drop” technique to select the various IEC 61850 communication services (objects) required to design the test case in a user friendly Graphical User Interface (GUI). This makes the service conformance testing more flexible for test engineers and system integrators especially in situations that require test case modifications. Also, the proposed software tool makes it easy to understand the various IEC 61850 services using the friendly GUI. 展开更多
关键词 IEC 61850 Intelligent Electronic Devices (IEDs) conformance Testing Model-Based Tool CLIENT-SERVER Communication Digital SUBSTATION Network
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Importance of conformance control in reinforcing synergy of CO_(2) EOR and sequestration 被引量:2
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作者 Yang Zhao Zhen-Hua Rui +7 位作者 Zheng Zhang Si-Wei Chen Ren-Feng Yang Kai Du Birol Dindoruk Tao Yang Erling H.Stenby Malcolm A.Wilson 《Petroleum Science》 SCIE CAS CSCD 2022年第6期3088-3106,共19页
Injecting CO2into hydrocarbon reservoirs can enhance the recovery of hydrocarbon resources,and simultaneously,CO2can be stored in the rese rvoirs,reducing considerable amount of carbon emissions in the atmosphere.Howe... Injecting CO2into hydrocarbon reservoirs can enhance the recovery of hydrocarbon resources,and simultaneously,CO2can be stored in the rese rvoirs,reducing considerable amount of carbon emissions in the atmosphere.However,injected CO_(2)tends to go through fractures,high-permeability channels and streaks present in reservoirs,resulting in inefficient hydrocarbon recovery coupled with low CO_(2)storage performance.Conformance treatments with CO_(2)-resistant crosslinked polymer gels were performed in this study to mitigate the CO_(2)channeling issue and promote the synergy between enhanced oil recovery(EOR) and subsurface sequestration of CO_(2).Based on a typical low-permeability CO_(2)-flooding reservoir in China,studies were performed to investigate the EOR and CO_(2)storage performance with and without conformance treatment.The effect of permeability contrast between the channels and rese rvoir matrices,treatment size,and plugging strength on the efficiency of oil recovery and CO_(2)storage was systematically investigated.The results indicated that after conformance treatments,the CO_(2)channeling problem was mitigated during CO_(2)flooding and storage.The injected CO_(2)was more effectively utilized to recover the hydrocarbons,and entered wider spectrum of pore spaces.Consequently,more CO_(2)was trapped underground.Pronounced factors on the synergy of EOR and CO_(2)storage were figured out.Compared with the treatment size,the CO_(2)storage efficiency was more sensitive to the plugging strength of the conformance treatment materials.This observation was important for conformance treatment design in CCUS-EOR projects.According to this study,the materials should reduce the channel permeability to make the channel/matrix permeability ratio below 30.The results demonstrate the importance of conformance treatment in maximizing the performance of CCUS-EOR process to achieve both oil recovery improvement and efficient carbon storage.This study provides guidelines for successful field applications of CO_(2)transport control in CO_(2)geo-utilization and storage. 展开更多
关键词 Enhanced oil recovery(EOR) CO_(2)geological sequestration conformance control Gel treatment CCUS Low-permeability reservoir
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Clinical Research on Three-Dimensional Conformal Radiotherapy of Non-Small Cell Lung Cancer 被引量:1
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作者 Baolin Yuan Tao Zhang Jianqi Luo Liang Zhang Suqun Chen Lina Yang Yong Wu Yuying Ma 《Chinese Journal of Clinical Oncology》 CSCD 2008年第4期263-267,共5页
OBJECTIVE To investigate the clinical efficacy and toxic effect of the 3-dimensional conformal radiation therapy (3DCRT) for non- small cell lung cancer (NSCLC). METHODS Fifty-two patients with the Stage-I and IV ... OBJECTIVE To investigate the clinical efficacy and toxic effect of the 3-dimensional conformal radiation therapy (3DCRT) for non- small cell lung cancer (NSCLC). METHODS Fifty-two patients with the Stage-I and IV NSCLC were treated with 3DCRT. Cross analysis of the clinical data was conducted in the comparison between the 52 cases with 3DCRT and the other 50 cases with the conventional radiation therapy (CRT). In the 3DCRT group, only the primary tumor and positive lymph-node draining area were included in the clinical target area, setting 4 to 6 coplanar or non-coplanar irradiation fields, with 2 Gy or 3 Gy/fraction, 1 fraction a day and 5 fractions per week. The total dose ranged from a test dose (DT) of 66 Gy to 72 Gy. In the CRT group, the field area contained the primary tumor plus the homolateral hilum of the lung, the mediastinum superior or hol-mediastinum, and opposed anteroposterior irradiation. When the dosage reached DT 36-40 Gy, an oblique portal administered radiation was conducted in order to avoid injuring the spinal cord. The DT was 1.8-2.0 Gy/fraction, 1 fraction a day, 5 fractions per week, with a total dose of 60 Gy to 70 Gy. RESULTS The therapeutic effect (CR + PR) was 90.4% in the 3DCRT group, and was 72% in the CRT group. There was statistically significant difference between the two groups, P 〈 0.01. There was a clinical symptom improvement attained by 96.5% and 86.4% respectively in the two groups, and there was a statistically significant difference between the groups, P 〈 0.01. The 6-month, 1 and 2-year overall survival rates were 92.3%, 75.0% and 42.3% in the 3DCRT group, and 76%, 60% and 30% in the CRT group, respectively. There was a significant difference in the 6-month overall survival rate between the groups, P 〈 0.05. There was no obvious significant difference in the 1 and 2-year overall survival rates between the two groups, P 〉 0.05. The toxic reaction was 12.5% and 23.7% respectively in the 3DCRT and CRT groups. Acute radioactive esophagitis and leucopenia were markedly lower in the 3DCRT group than in the CRT group. There was a statistically significant difference between the groups, P 〈 0.05. No toxic reaction of Stage-III and over was found in the 3DCRT group during radiation therapy. CONCLUSION The 3DCRT method has a satisfactory shortterm efficacy and improvement of clinical symptoms in treating NSCLC, with a mild toxic reaction and good tolerance in patients. It can be used for enhancing the tumor-control rate and bettering the quality of life. 展开更多
关键词 non-small cell lung cancer RADIOTHERAPY threedimensional conformal radiotherapy conventional radiation therapy.
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Concurrent gemcitabine and cisplatin combined with 3D conformal radiotherapy for stage III non-small cell lung cancer 被引量:1
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作者 Qinghua Ke Guoquan Fu Yaowu Bian Daiwen Jiang Jiyuan Yang 《The Chinese-German Journal of Clinical Oncology》 CAS 2009年第3期156-159,共4页
Objective: To study the toxicities and efficacy of concurrent gemcitabine plus cisplatin combined with three-dimensional conformal radiotherapy for stage Ⅲ non-small cell lung cancer (NSCLC). Methods: Thirty-six ... Objective: To study the toxicities and efficacy of concurrent gemcitabine plus cisplatin combined with three-dimensional conformal radiotherapy for stage Ⅲ non-small cell lung cancer (NSCLC). Methods: Thirty-six patients with pathologically diagnosed NSCLC received radiotherapy and concurrent chemotherapy. There were 22 patients with stage Ilia and 14 patients with IIIb. Radiotherapy was given a total of 60-70 Gy in conventional fractionation. Chemotherapy included gemcitabine (600 mg/m^2) and cisplatin (20 mg/m^2), once per week. Results: Thirty-two patients received a total dose of 60-72 Gy. Two patients received 56 Gy and another two patients received 58 Gy. Thirty-four patients received 4-6 weeks of chemotherapy, while two patients received only 2 weeks of chemotherapy. The overall response rate (CR + PR), complete response rate (CR), partially response rate (PR) were 83.3% (30/36), 11.1% (4/36) and 72.2% (26/36) respectively. The median follow-up duration was 18.4 months. The 1- and 2-year overall survival rates were 77.8% (28/36) and 55.6% (20/36), respectively. Conclusion: Concurrent gemcitabine and cisplatin combined with three-dimensional conformal radiotherapy for stage III non-small cell lung cancer is effective and well tolerated. Lone-term results need further study. 展开更多
关键词 non-small cell lung cancer (NSCLC) three-dimensional conformal radiotherapy (3DCRT) CHEMOTHERAPY GEMCITABINE cispiatin PROGNOSIS
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3D‑Printed Carbon‑Based Conformal Electromagnetic Interference Shielding Module for Integrated Electronics 被引量:4
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作者 Shaohong Shi Yuheng Jiang +5 位作者 Hao Ren Siwen Deng Jianping Sun Fangchao Cheng Jingjing Jing Yinghong Chen 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第5期87-101,共15页
Electromagnetic interference shielding(EMI SE)modules are the core com-ponent of modern electronics.However,the tra-ditional metal-based SE modules always take up indispensable three-dimensional space inside electroni... Electromagnetic interference shielding(EMI SE)modules are the core com-ponent of modern electronics.However,the tra-ditional metal-based SE modules always take up indispensable three-dimensional space inside electronics,posing a major obstacle to the integra-tion of electronics.The innovation of integrating 3D-printed conformal shielding(c-SE)modules with packaging materials onto core electronics offers infinite possibilities to satisfy ideal SE func-tion without occupying additional space.Herein,the 3D printable carbon-based inks with various proportions of graphene and carbon nanotube nanoparticles are well-formulated by manipulating their rheological peculiarity.Accordingly,the free-constructed architectures with arbitrarily-customized structure and multifunctionality are created via 3D printing.In particular,the SE performance of 3D-printed frame is up to 61.4 dB,simultaneously accompanied with an ultralight architecture of 0.076 g cm^(-3) and a superhigh specific shielding of 802.4 dB cm3 g^(-1).Moreover,as a proof-of-concept,the 3D-printed c-SE module is in situ integrated into core electronics,successfully replacing the traditional metal-based module to afford multiple functions for electromagnetic compatibility and thermal dissipa-tion.Thus,this scientific innovation completely makes up the blank for assembling carbon-based c-SE modules and sheds a brilliant light on developing the next generation of high-performance shielding materials with arbitrarily-customized structure for integrated electronics. 展开更多
关键词 3D printing Carbon-based nanoparticles conformal electromagnetic interference shielding Integrated electronics
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Classifying rockburst with confidence:A novel conformal prediction approach 被引量:2
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作者 Bemah Ibrahim Isaac Ahenkorah 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第1期51-64,共14页
The scientific community recognizes the seriousness of rockbursts and the need for effective mitigation measures.The literature reports various successful applications of machine learning(ML)models for rockburst asses... The scientific community recognizes the seriousness of rockbursts and the need for effective mitigation measures.The literature reports various successful applications of machine learning(ML)models for rockburst assessment;however,a significant question remains unanswered:How reliable are these models,and at what confidence level are classifications made?Typically,ML models output single rockburst grade even in the face of intricate and out-of-distribution samples,without any associated confidence value.Given the susceptibility of ML models to errors,it becomes imperative to quantify their uncertainty to prevent consequential failures.To address this issue,we propose a conformal prediction(CP)framework built on traditional ML models(extreme gradient boosting and random forest)to generate valid classifications of rockburst while producing a measure of confidence for its output.The proposed framework guarantees marginal coverage and,in most cases,conditional coverage on the test dataset.The CP was evaluated on a rockburst case in the Sanshandao Gold Mine in China,where it achieved high coverage and efficiency at applicable confidence levels.Significantly,the CP identified several“confident”classifications from the traditional ML model as unreliable,necessitating expert verification for informed decision-making.The proposed framework improves the reliability and accuracy of rockburst assessments,with the potential to bolster user confidence. 展开更多
关键词 ROCKBURST Machine learning Uncertainty quantification conformal prediction
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Monaco计划系统中Conformality函数对宫颈癌容积旋转调强计划的影响
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作者 郗旺 赵媛媛 +2 位作者 王小秋 陈晓南 何瑞龙 《生物医学工程与临床》 CAS 2024年第4期515-520,共6页
目的 探讨Monaco计划系统中Conformality函数的不同参数值对计划质量的影响。方法 选择15例宫颈癌患者,年龄46~74岁,中位年龄51岁。分别采用Conformality函数参数值为0.25、0.50、0.75、1.00,以及不加函数设计容积旋转调强放射治疗(VMAT... 目的 探讨Monaco计划系统中Conformality函数的不同参数值对计划质量的影响。方法 选择15例宫颈癌患者,年龄46~74岁,中位年龄51岁。分别采用Conformality函数参数值为0.25、0.50、0.75、1.00,以及不加函数设计容积旋转调强放射治疗(VMAT)计划,评估靶区及危及器官(OAR)剂量学参数和20 Gy、30 Gy、40 Gy等剂量线的体积和计划执行效率。结果 不同Conformality函数参数值计划的靶区剂量学差异均有统计学意义(P <0.05)。Conformality函数参数值为0.25时,靶区的Dmax、Dmin、Dmean与不加函数的增减幅度分别为2.45%、-0.96%、1.48%,适形度指数(CI)、均匀性指数(HI)增加0.05、0.04。当Conformality函数参数值> 0.50时,CI、HI基本无改变。小肠、结肠、左右股骨头的剂量学差异无统计学意义(P> 0.05)。当Conformality函数参数值为0.25时,直肠的V30、V40[(81.80±7.74)%、(63.44±10.23)%]、膀胱V30、V40[(78.82±5.69)%、(56.40±9.33)%]、正常组织V_(20)、V_(30)、V_(40)的体积[(6 137.64±622.88) cm^(3)、(2 903.55±221.08) cm^(3)、(1 862.93±112.81) cm^(3)]最低。Conformality函数在不同参数之下,膀胱、直肠V_(30)、V_(40)差异均具有统计学意义(P <0.05)。随着Conformality函数参数值增大机器参数值随之减小,机器跳数(MU)、控制点个数(CP)、执行时间(DT)在各Conformality函数参数值之间差异均有统计学意义(P <0.05)。结论 对于宫颈癌在Monaco计划系统中恰当使用Conformality函数设计计划可以提高计划质量,参数值设置在0.25~0.75为宜。综合剂量学参数及计划执行效率,推荐使用0.50。 展开更多
关键词 Monaco计划系统 宫颈癌 conformality函数 剂量学
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