Calix[4]-crown-5-sulfonyl cyclothiourea derivatives 6 and 7 were synthesized from calix[4]-crown-5-monosulfonylethylenediamine derivatives 4 and 5 and carbon disulfide through nucleophilic addition and subsequent cycl...Calix[4]-crown-5-sulfonyl cyclothiourea derivatives 6 and 7 were synthesized from calix[4]-crown-5-monosulfonylethylenediamine derivatives 4 and 5 and carbon disulfide through nucleophilic addition and subsequent cyclization of intramolecule at room temperature in aqueous solution. The advantages of the novel protocol are the mild reaction condition, free organic solvent, simple final treatment, easy isolation of products and excellent yields.展开更多
基金Financial support from the National Natural Science Foundation of China(No.20802049) and Program for New Century Excellent Talents in University of Tianjin City
文摘Calix[4]-crown-5-sulfonyl cyclothiourea derivatives 6 and 7 were synthesized from calix[4]-crown-5-monosulfonylethylenediamine derivatives 4 and 5 and carbon disulfide through nucleophilic addition and subsequent cyclization of intramolecule at room temperature in aqueous solution. The advantages of the novel protocol are the mild reaction condition, free organic solvent, simple final treatment, easy isolation of products and excellent yields.
