The distributed hybrid processing optimization problem of non-cooperative targets is an important research direction for future networked air-defense and anti-missile firepower systems. In this paper, the air-defense ...The distributed hybrid processing optimization problem of non-cooperative targets is an important research direction for future networked air-defense and anti-missile firepower systems. In this paper, the air-defense anti-missile targets defense problem is abstracted as a nonconvex constrained combinatorial optimization problem with the optimization objective of maximizing the degree of contribution of the processing scheme to non-cooperative targets, and the constraints mainly consider geographical conditions and anti-missile equipment resources. The grid discretization concept is used to partition the defense area into network nodes, and the overall defense strategy scheme is described as a nonlinear programming problem to solve the minimum defense cost within the maximum defense capability of the defense system network. In the solution of the minimum defense cost problem, the processing scheme, equipment coverage capability, constraints and node cost requirements are characterized, then a nonlinear mathematical model of the non-cooperative target distributed hybrid processing optimization problem is established, and a local optimal solution based on the sequential quadratic programming algorithm is constructed, and the optimal firepower processing scheme is given by using the sequential quadratic programming method containing non-convex quadratic equations and inequality constraints. Finally, the effectiveness of the proposed method is verified by simulation examples.展开更多
Robotic systems are expected to play an increasingly important role in future space activities. The robotic on-orbital service, whose key is the capturing technology, becomes a research hot spot in recent years. This ...Robotic systems are expected to play an increasingly important role in future space activities. The robotic on-orbital service, whose key is the capturing technology, becomes a research hot spot in recent years. This paper studies the dynamics modeling and impedance control of a multi-arm free-flying space robotic system capturing a non-cooperative target. Firstly, a control-oriented dynamics model is essential in control algorithm design and code realization. Unlike a numerical algorithm, an analytical approach is suggested. Using a general and a quasi-coordinate Lagrangian formulation, the kinematics and dynamics equations are derived.Then, an impedance control algorithm is developed which allows coordinated control of the multiple manipulators to capture a target.Through enforcing a reference impedance, end-effectors behave like a mass-damper-spring system fixed in inertial space in reaction to any contact force between the capture hands and the target. Meanwhile, the position and the attitude of the base are maintained stably by using gas jet thrusters to work against the manipulators' reaction. Finally, a simulation by using a space robot with two manipulators and a free-floating non-cooperative target is illustrated to verify the effectiveness of the proposed method.展开更多
A passive compliant non-cooperative target capture mechanism is designed to maintain the non-cooperative target on-orbit. When the relative position between capture mechanism and satellite is confirmed,a pair of four-...A passive compliant non-cooperative target capture mechanism is designed to maintain the non-cooperative target on-orbit. When the relative position between capture mechanism and satellite is confirmed,a pair of four-bar linkages lock the docking ring,which is used for connecting the satellite and the rocket. The mathematical model of capture mechanism and capture space is built by the Denavit-Hartenberg(D-H)method,and the torque of each joint is analyzed by the Lagrange dynamic equation. Besides,the capture condition and the torque of every joint under different capture conditions are analyzed by simulation in MSC. Adams. The results indicate that the mechanism can capture the non-cooperative target satellite in a wide range. During the process of capture,the passive compliant mechanism at the bottom can increase capture space,thereby reducing the difficulty and enhance stability of the capture.展开更多
Robotic grippers have been used in industry as end-effectors but are usually limited to operations in pre-defined workspace.However,few devices can capture irregularly shaped dynamic targets in space,underwater and ot...Robotic grippers have been used in industry as end-effectors but are usually limited to operations in pre-defined workspace.However,few devices can capture irregularly shaped dynamic targets in space,underwater and other unstructured environments.In this paper,a novel continuum arm group mechanism inspired by the morphology and motions of sea anemones is proposed.It is able to dissipate and absorb the kinetic energy of a fast moving target in omni-direction and utilize multiple arms to wrap and lock the target without accurate positioning control.Wire-driven actuation systems are implemented in the individual continuum arms,achieving both bending motion and stiffness regulation.Through finite element method,the influence of different configurations of the continuum arm group on the capture performance is analyzed.A robotic prototype is constructed and tested,showing the presented arm group mechanism has high adaptability to capture targets with different sizes,shapes,and incident angles.展开更多
The high frequency hybrid technique based on an iterative Physical Optics(PC)) and the method of equivalent current (MEC) approach is developed for predicting rangeresolution of the Radar Cross Section (RCS) in the sp...The high frequency hybrid technique based on an iterative Physical Optics(PC)) and the method of equivalent current (MEC) approach is developed for predicting rangeresolution of the Radar Cross Section (RCS) in the spatial domain. We introduce the hybrid highfrequency method to simulate range resolution of the extremely large target in the near zone. Thispaper applies this method to simulate the range resolution of the two 1 m X 1 m plates and the ship.The study improves the speed of simulatingthe range resolution of the extremely large target and isprepared for the application of the extrapolation and interpolation in the spatial domain.展开更多
For localisation of unknown non-cooperative targets in space,the existence of interference points causes inaccuracy of pose estimation while utilizing point cloud registration.To address this issue,this paper proposes...For localisation of unknown non-cooperative targets in space,the existence of interference points causes inaccuracy of pose estimation while utilizing point cloud registration.To address this issue,this paper proposes a new iterative closest point(ICP)algorithm combined with distributed weights to intensify the dependability and robustness of the non-cooperative target localisation.As interference points in space have not yet been extensively studied,we classify them into two broad categories,far interference points and near interference points.For the former,the statistical outlier elimination algorithm is employed.For the latter,the Gaussian distributed weights,simultaneously valuing with the variation of the Euclidean distance from each point to the centroid,are commingled to the traditional ICP algorithm.In each iteration,the weight matrix W in connection with the overall localisation is obtained,and the singular value decomposition is adopted to accomplish high-precision estimation of the target pose.Finally,the experiments are implemented by shooting the satellite model and setting the position of interference points.The outcomes suggest that the proposed algorithm can effectively suppress interference points and enhance the accuracy of non-cooperative target pose estimation.When the interference point number reaches about 700,the average error of angle is superior to 0.88°.展开更多
With the Regional Ocean Modeling System(ROMS),this paper investigates the sensitive areas in targeted observation for predicting the Kuroshio large meander(LM)path using the conditional nonlinear optimal perturbation ...With the Regional Ocean Modeling System(ROMS),this paper investigates the sensitive areas in targeted observation for predicting the Kuroshio large meander(LM)path using the conditional nonlinear optimal perturbation approach.To identify the sensitive areas,the optimal initial errors(OIEs)featuring the largest nonlinear evolution in the LM prediction are first calculated;the resulting OIEs are localized mainly in the upper 2500 m over the LM upstream region,and their spatial structure has certain similarities with that of the optimal triggering perturbation.Based on this spatial structure,the sensitive areas are successfully identified,located southeast of Kyushu in the region(29°–32°N,131°–134°E).A series of sensitivity experiments indicate that both the positions and the spatial structure of initial errors have important effects on the LM prediction,verifying the validity of the sensitive areas.Then,the effect of targeted observation in the sensitive areas is evaluated through observing system simulation experiments.When targeted observation is implemented in the identified sensitive areas,the prediction errors are effectively reduced,and the prediction skill of the LM event is improved significantly.This provides scientific guidance for ocean observations related to enhancing the prediction skill of the LM event.展开更多
For high precision calibration of camera with large field-of-view,massive calibration points will be needed if traditional methods are selected,which makes the calibration complex and time-consuming.In order to solve ...For high precision calibration of camera with large field-of-view,massive calibration points will be needed if traditional methods are selected,which makes the calibration complex and time-consuming.In order to solve this problem,a calibration method based on flexible planar target is proposed.In this method,distortion factor is firstly acquired by the invariance of cross ratio,and existing feature points are adjusted with the distortion factor.Then,a large number of points that will be used for the calibration are constructed with the adjusted feature points.Simultaneously,Tsai method is modified so as to reduce the complexity of calibration,which makes the process linear.The simulation and real experiments show that the method proposed in this paper is simple,linear,accurate and robust,and the precision of this method is close to that of Tsai method using abundant points.The method can satisfy the requirement of high precision calibration for camera with large field-of-view.展开更多
The existing research results show that a fixed single station must conduct three consecutive frequency shift measurements and obtain the target’s moving speed by constructing two frequency difference equations. This...The existing research results show that a fixed single station must conduct three consecutive frequency shift measurements and obtain the target’s moving speed by constructing two frequency difference equations. This article proposes a new method that requires only two consecutive measurements. While using the azimuth measurement to obtain the angular difference between two radial distances, it also conducts two consecutive Doppler frequency shift measurements at the same target azimuth. On the basis of this measurement, a frequency difference equation is first constructed and solved jointly with the Doppler frequency shift equation. By eliminating the velocity variable and using the measured angular difference to obtain the target’s lead angle, the target’s velocity can be solved by using the Doppler frequency shift equation again. The new method avoids the condition that the target must move equidistantly, which not only provides an achievable method for engineering applications but also lays a good foundation for further exploring the use of steady-state signals to achieve passive positioning.展开更多
Inertial characteristics of non-cooperative targets are crucial for space capture and sub-sequent on-orbit servicing.Previous methods for identifying inertial parameters involve proximity operations,which are associat...Inertial characteristics of non-cooperative targets are crucial for space capture and sub-sequent on-orbit servicing.Previous methods for identifying inertial parameters involve proximity operations,which are associated with the risk of collision with non-cooperative targets.This paper introduces a long-range,contactless method for identifying the inertial parameters of a non-cooperative target during the pre-capture phase.Specifically,electrostatic interaction is used as an external excitation to alter the target's motion.A force estimation algorithm that uses measure-ments from visual and potential sensors is proposed to estimate the electrostatic interaction and eliminate the need for force sensors.Furthermore,a recursive estimation-identification framework is presented to concurrently estimate the coupled motion state,weak electrostatic interaction,and inertial parameters of the target.The simulation results show that the proposed method extends the identification distance to 170 times that of the previous method while maintaining high identifica-tion precision forall parameters.展开更多
This paper investigates an analytical optimal pose tracking control problem for chaser spacecraft during the close-range proximity operations with a non-cooperative space target subject to attitude tumbling and unknow...This paper investigates an analytical optimal pose tracking control problem for chaser spacecraft during the close-range proximity operations with a non-cooperative space target subject to attitude tumbling and unknown orbital maneuvering.Firstly,the relative translational motion between the orbital target and the chaser spacecraft is described in the Line-of-Sight(LOS)coordinate frame along with attitude quaternion dynamics.Then,based on the coupled 6-Degree of Freedom(DOF)pose dynamic model,an analytical optimal control action consisting of constrained optimal control value,application time and its duration are proposed via exploring the iterative sequential action control algorithm.Meanwhile,the global closed-loop asymptotic stability of the proposed predictive control action is presented and discussed.Compared with traditional proximity control schemes,the highlighting advantages are that the application time and duration of the devised controller is applied discretely in light of the influence of the instantaneous pose configuration on the pose tracking performance with less energy consumptions rather than at each sample time.Finally,three groups of illustrative examples are organized to validate the effectiveness of the proposed analytical optimal pose tracking control scheme.展开更多
Objectives To evaluate the very long-term safety and effectiveness of drug-eluting stents (DES) compared to bare-metal stents (BMS) for patients with large coronary vessels. Methods From April 2004 to October 2006...Objectives To evaluate the very long-term safety and effectiveness of drug-eluting stents (DES) compared to bare-metal stents (BMS) for patients with large coronary vessels. Methods From April 2004 to October 2006, 2407 consecutive patients undergoing de novo lesion percutaneous coronary intervention with reference vessel diameter greater than or equal to 3.5 mm at Fu Wai Hospital in Beijing, China, were prospectively enrolled into this study. We obtained 9-year clinical outcomes including death, myocardial infarction (MI), thrombosis, target lesion revascularization (TLR), target vessel revascularization (TVR), and major adverse cardiac events (MACE, the composite of death, MI, and TVR). We performed Cox's proportional-hazards models to assess relative risks of all the outcome measures after propensity match. Results After propensity scoring, 514 DES-treated patients were matched to 514 BMS-treated patients. The patients treated with BMS were associated with higher risk ofTLR (HR: 2.55, 95%CI: 1.520-4.277, P = 0.0004) and TVR (HR: 1.889, 95%CI: 1.185-3.011, P = 0.0075), but the rates of death/MI and MACE were not statistically different. All Academic Research Consortium definition stent thrombosis at 9-year were comparable in the two groups. Conclusions During long-term follow-up through nine years, use of DES in patients with large coronary arteries was still associated with significant reductions in the risks of TLR and TVR.展开更多
BACKGROUND Diffuse large B-cell lymphoma(DLBCL)is a common non-Hodgkin lymphoma.The development of immunotherapy greatly improves the patient prognosis but there are some exceptions.Thus,screening for better biomarker...BACKGROUND Diffuse large B-cell lymphoma(DLBCL)is a common non-Hodgkin lymphoma.The development of immunotherapy greatly improves the patient prognosis but there are some exceptions.Thus,screening for better biomarkers for prognostic evaluation could contribute to the treatment of DLBCL patients.AIM To screen the novel mediators involved in the development of DLBCL.METHODS The GSE60 dataset was applied to identify the differentially expressed genes(DEGs)in DLBCL,and the principal components analysis plot was used to determine the quality of the included samples.The protein-protein interactions were analyzed by the STRING tool.The key hub genes were entered into to the GEPIA database to determine their expressions in DLBCL.Furthermore,these hub gene alterations were analyzed in cBioportal.The UALCAN portal was employed to analyze the expression of the hub genes in different stages of DLBCL.The Estimation of Stromal and Immune cells in Malignant Tumor tissues using Expression data Score was conducted to evaluate the correlation between the gene expression and tumor purity.The gene-gene correlation analysis was conducted in the GEPIA.The stromal score analysis was conducted in TIMER to confirm the correlation between the gene expression and infiltrated stromal cells.The correlation between the indicated genes and infiltration level of cancerassociated fibroblasts(CAFs)was also completed in TIMER with two methods,MCP-Counter and Tumor immune dysfunction and exclusion.The correlation between fibronectin(FN1)protein level and secreted protein acidic and cysteinerich(SPARC)messenger ribonucleic acid expression was confirmed in the cBioportal.RESULTS The top 20 DEGs in DLBCL were identified,and the principal components analysis plot confirmed the quality of the significant DEGs.The pairwise correlation coefficient analysis among all samples showed that these DEGs have a certain co-expression pattern.The DEGs were subjected to STRING to identify the hub genes,alpha-2-macroglobulin(A2M),cathepsin B(CTSB),FN1,matrix metallopeptidase 9(MMP9),and SPARC.The five hub genes were confirmed to be overexpressed in DLBCL.The cBioportal portal detected these five hub genes that had gene alteration,including messenger ribonucleic acid high amplification and missense mutation,and the gene alteration percentages of A2M,FN1,CTSB,MMP9,and SPARC were 5%,8%,5%,2.7%,and 5%,respectively.Furthermore,the five hub genes had a potential positive correlation with tumor stage.The correlation analysis between the five genes and tumor purity confirmed that the five genes were overexpressed in DLBCL and had a positive correlation with the development of DLBCL.More interestingly,the five genes had a significant correlation with the stromal infiltration scores.The correlation analysis between the fives genes and CAFs also showed a significant value,among which the top two genes,FN1 and SPARC,had a remarkable co-expression pattern.CONCLUSION The top DEGs were identified,and the five hub genes were overexpressed in DLBCL.Furthermore,the gene alterations were confirmed and the positive correlation with tumor purity revealed the overexpression of the five genes and close association with the development of DLBCL.More interestingly,the five genes were positively correlated with stromal infiltration,especially in CAFs.The top two genes,FN1 and SPARC,showed a co-expression pattern,which indicates their potential as novel therapeutic targets for DLBCL.展开更多
随着深度学习在国内目标检测的不断应用,常规的大、中目标检测已经取得惊人的进步,但由于卷积网络本身的局限性,针对小目标检测依然会出现漏检、误检的问题,以数据集Visdrone2019和数据集FloW-Img为例,对YOLOv7模型进行研究,在网络结构...随着深度学习在国内目标检测的不断应用,常规的大、中目标检测已经取得惊人的进步,但由于卷积网络本身的局限性,针对小目标检测依然会出现漏检、误检的问题,以数据集Visdrone2019和数据集FloW-Img为例,对YOLOv7模型进行研究,在网络结构上对骨干网的ELAN模块进行改进,将Focal NeXt block加入到ELAN模块的长短梯度路径中融合来强化输出小目标的特征质量和提高输出特征包含的上下文信息含量,在头部网络引入RepLKDeXt模块,该模块不仅可以取代SPPCSPC模块来简化模型整体结构还可以利用多通道、大卷积核和Cat操作来优化ELAN-H结构,最后引入SIOU损失函数取代CIOU函数以此提高该模型的鲁棒性。结果表明改进后的YOLOv7模型参数量减少计算复杂性降低并在小目标密度高的Visdrone 2019数据集上的检测性能近似不变,在小目标稀疏的FloW-Img数据集上涨幅9.05个百分点,进一步简化了模型并增加了模型的适用范围。展开更多
基金supported by the National Natural Science Foundation of China (61903025)the Fundamental Research Funds for the Cent ral Universities (FRF-IDRY-20-013)。
文摘The distributed hybrid processing optimization problem of non-cooperative targets is an important research direction for future networked air-defense and anti-missile firepower systems. In this paper, the air-defense anti-missile targets defense problem is abstracted as a nonconvex constrained combinatorial optimization problem with the optimization objective of maximizing the degree of contribution of the processing scheme to non-cooperative targets, and the constraints mainly consider geographical conditions and anti-missile equipment resources. The grid discretization concept is used to partition the defense area into network nodes, and the overall defense strategy scheme is described as a nonlinear programming problem to solve the minimum defense cost within the maximum defense capability of the defense system network. In the solution of the minimum defense cost problem, the processing scheme, equipment coverage capability, constraints and node cost requirements are characterized, then a nonlinear mathematical model of the non-cooperative target distributed hybrid processing optimization problem is established, and a local optimal solution based on the sequential quadratic programming algorithm is constructed, and the optimal firepower processing scheme is given by using the sequential quadratic programming method containing non-convex quadratic equations and inequality constraints. Finally, the effectiveness of the proposed method is verified by simulation examples.
基金supported by the National Natural Science Foundation of China (61673009)。
文摘Robotic systems are expected to play an increasingly important role in future space activities. The robotic on-orbital service, whose key is the capturing technology, becomes a research hot spot in recent years. This paper studies the dynamics modeling and impedance control of a multi-arm free-flying space robotic system capturing a non-cooperative target. Firstly, a control-oriented dynamics model is essential in control algorithm design and code realization. Unlike a numerical algorithm, an analytical approach is suggested. Using a general and a quasi-coordinate Lagrangian formulation, the kinematics and dynamics equations are derived.Then, an impedance control algorithm is developed which allows coordinated control of the multiple manipulators to capture a target.Through enforcing a reference impedance, end-effectors behave like a mass-damper-spring system fixed in inertial space in reaction to any contact force between the capture hands and the target. Meanwhile, the position and the attitude of the base are maintained stably by using gas jet thrusters to work against the manipulators' reaction. Finally, a simulation by using a space robot with two manipulators and a free-floating non-cooperative target is illustrated to verify the effectiveness of the proposed method.
基金supported by the National Natural Science Foundation of China(No.51675264)
文摘A passive compliant non-cooperative target capture mechanism is designed to maintain the non-cooperative target on-orbit. When the relative position between capture mechanism and satellite is confirmed,a pair of four-bar linkages lock the docking ring,which is used for connecting the satellite and the rocket. The mathematical model of capture mechanism and capture space is built by the Denavit-Hartenberg(D-H)method,and the torque of each joint is analyzed by the Lagrange dynamic equation. Besides,the capture condition and the torque of every joint under different capture conditions are analyzed by simulation in MSC. Adams. The results indicate that the mechanism can capture the non-cooperative target satellite in a wide range. During the process of capture,the passive compliant mechanism at the bottom can increase capture space,thereby reducing the difficulty and enhance stability of the capture.
基金Supported by National Key R&D Program of China(Grant Nos.2019YFB1309800,2018YFB1304600)National Natural Science Foundation of China(Grant No.51875393)State Key Laboratory of Robotics Foundation-China(Grant No.2019-O04).
文摘Robotic grippers have been used in industry as end-effectors but are usually limited to operations in pre-defined workspace.However,few devices can capture irregularly shaped dynamic targets in space,underwater and other unstructured environments.In this paper,a novel continuum arm group mechanism inspired by the morphology and motions of sea anemones is proposed.It is able to dissipate and absorb the kinetic energy of a fast moving target in omni-direction and utilize multiple arms to wrap and lock the target without accurate positioning control.Wire-driven actuation systems are implemented in the individual continuum arms,achieving both bending motion and stiffness regulation.Through finite element method,the influence of different configurations of the continuum arm group on the capture performance is analyzed.A robotic prototype is constructed and tested,showing the presented arm group mechanism has high adaptability to capture targets with different sizes,shapes,and incident angles.
基金Supported by the National Natural Science Foundation of China(60301007)
文摘The high frequency hybrid technique based on an iterative Physical Optics(PC)) and the method of equivalent current (MEC) approach is developed for predicting rangeresolution of the Radar Cross Section (RCS) in the spatial domain. We introduce the hybrid highfrequency method to simulate range resolution of the extremely large target in the near zone. Thispaper applies this method to simulate the range resolution of the two 1 m X 1 m plates and the ship.The study improves the speed of simulatingthe range resolution of the extremely large target and isprepared for the application of the extrapolation and interpolation in the spatial domain.
基金supported by the National Natural Science Foundation of China(51875535)the Natural Science Foundation for Young Scientists of Shanxi Province(201901D211242201701D221017)。
文摘For localisation of unknown non-cooperative targets in space,the existence of interference points causes inaccuracy of pose estimation while utilizing point cloud registration.To address this issue,this paper proposes a new iterative closest point(ICP)algorithm combined with distributed weights to intensify the dependability and robustness of the non-cooperative target localisation.As interference points in space have not yet been extensively studied,we classify them into two broad categories,far interference points and near interference points.For the former,the statistical outlier elimination algorithm is employed.For the latter,the Gaussian distributed weights,simultaneously valuing with the variation of the Euclidean distance from each point to the centroid,are commingled to the traditional ICP algorithm.In each iteration,the weight matrix W in connection with the overall localisation is obtained,and the singular value decomposition is adopted to accomplish high-precision estimation of the target pose.Finally,the experiments are implemented by shooting the satellite model and setting the position of interference points.The outcomes suggest that the proposed algorithm can effectively suppress interference points and enhance the accuracy of non-cooperative target pose estimation.When the interference point number reaches about 700,the average error of angle is superior to 0.88°.
基金The National Natural Science Foundation of China under contract Nos 41906003 and 41906022the Strategic Priority Research Program of Chinese Academy of Sciences under contract No.XDA20060502+1 种基金the Fundamental Research Funds for the Central Universities under contract No.B200201011the Basic Research Projects of Key Scientific Research Projects Plan in Henan Higher Education Institutions under contract No.20zx003.
文摘With the Regional Ocean Modeling System(ROMS),this paper investigates the sensitive areas in targeted observation for predicting the Kuroshio large meander(LM)path using the conditional nonlinear optimal perturbation approach.To identify the sensitive areas,the optimal initial errors(OIEs)featuring the largest nonlinear evolution in the LM prediction are first calculated;the resulting OIEs are localized mainly in the upper 2500 m over the LM upstream region,and their spatial structure has certain similarities with that of the optimal triggering perturbation.Based on this spatial structure,the sensitive areas are successfully identified,located southeast of Kyushu in the region(29°–32°N,131°–134°E).A series of sensitivity experiments indicate that both the positions and the spatial structure of initial errors have important effects on the LM prediction,verifying the validity of the sensitive areas.Then,the effect of targeted observation in the sensitive areas is evaluated through observing system simulation experiments.When targeted observation is implemented in the identified sensitive areas,the prediction errors are effectively reduced,and the prediction skill of the LM event is improved significantly.This provides scientific guidance for ocean observations related to enhancing the prediction skill of the LM event.
基金Sponsored by the Fundamental Research Funds for the Central Universities(Grant No.HIT.NSRIF.2014019)
文摘For high precision calibration of camera with large field-of-view,massive calibration points will be needed if traditional methods are selected,which makes the calibration complex and time-consuming.In order to solve this problem,a calibration method based on flexible planar target is proposed.In this method,distortion factor is firstly acquired by the invariance of cross ratio,and existing feature points are adjusted with the distortion factor.Then,a large number of points that will be used for the calibration are constructed with the adjusted feature points.Simultaneously,Tsai method is modified so as to reduce the complexity of calibration,which makes the process linear.The simulation and real experiments show that the method proposed in this paper is simple,linear,accurate and robust,and the precision of this method is close to that of Tsai method using abundant points.The method can satisfy the requirement of high precision calibration for camera with large field-of-view.
文摘The existing research results show that a fixed single station must conduct three consecutive frequency shift measurements and obtain the target’s moving speed by constructing two frequency difference equations. This article proposes a new method that requires only two consecutive measurements. While using the azimuth measurement to obtain the angular difference between two radial distances, it also conducts two consecutive Doppler frequency shift measurements at the same target azimuth. On the basis of this measurement, a frequency difference equation is first constructed and solved jointly with the Doppler frequency shift equation. By eliminating the velocity variable and using the measured angular difference to obtain the target’s lead angle, the target’s velocity can be solved by using the Doppler frequency shift equation again. The new method avoids the condition that the target must move equidistantly, which not only provides an achievable method for engineering applications but also lays a good foundation for further exploring the use of steady-state signals to achieve passive positioning.
基金supported by the National Natural Science Foundation of China (No.6200326).
文摘Inertial characteristics of non-cooperative targets are crucial for space capture and sub-sequent on-orbit servicing.Previous methods for identifying inertial parameters involve proximity operations,which are associated with the risk of collision with non-cooperative targets.This paper introduces a long-range,contactless method for identifying the inertial parameters of a non-cooperative target during the pre-capture phase.Specifically,electrostatic interaction is used as an external excitation to alter the target's motion.A force estimation algorithm that uses measure-ments from visual and potential sensors is proposed to estimate the electrostatic interaction and eliminate the need for force sensors.Furthermore,a recursive estimation-identification framework is presented to concurrently estimate the coupled motion state,weak electrostatic interaction,and inertial parameters of the target.The simulation results show that the proposed method extends the identification distance to 170 times that of the previous method while maintaining high identifica-tion precision forall parameters.
基金This study was co-supported by the National Natural Science Foundation of China(Nos.62003371,62373379,62103446,61273351,62073343)the Outstanding Youth Fund of Hunan Provincial Natural Science,China(No.2022JJ20081)the Innovation Driven Project of Central South University,China(No.2023CXQD066).
文摘This paper investigates an analytical optimal pose tracking control problem for chaser spacecraft during the close-range proximity operations with a non-cooperative space target subject to attitude tumbling and unknown orbital maneuvering.Firstly,the relative translational motion between the orbital target and the chaser spacecraft is described in the Line-of-Sight(LOS)coordinate frame along with attitude quaternion dynamics.Then,based on the coupled 6-Degree of Freedom(DOF)pose dynamic model,an analytical optimal control action consisting of constrained optimal control value,application time and its duration are proposed via exploring the iterative sequential action control algorithm.Meanwhile,the global closed-loop asymptotic stability of the proposed predictive control action is presented and discussed.Compared with traditional proximity control schemes,the highlighting advantages are that the application time and duration of the devised controller is applied discretely in light of the influence of the instantaneous pose configuration on the pose tracking performance with less energy consumptions rather than at each sample time.Finally,three groups of illustrative examples are organized to validate the effectiveness of the proposed analytical optimal pose tracking control scheme.
文摘Objectives To evaluate the very long-term safety and effectiveness of drug-eluting stents (DES) compared to bare-metal stents (BMS) for patients with large coronary vessels. Methods From April 2004 to October 2006, 2407 consecutive patients undergoing de novo lesion percutaneous coronary intervention with reference vessel diameter greater than or equal to 3.5 mm at Fu Wai Hospital in Beijing, China, were prospectively enrolled into this study. We obtained 9-year clinical outcomes including death, myocardial infarction (MI), thrombosis, target lesion revascularization (TLR), target vessel revascularization (TVR), and major adverse cardiac events (MACE, the composite of death, MI, and TVR). We performed Cox's proportional-hazards models to assess relative risks of all the outcome measures after propensity match. Results After propensity scoring, 514 DES-treated patients were matched to 514 BMS-treated patients. The patients treated with BMS were associated with higher risk ofTLR (HR: 2.55, 95%CI: 1.520-4.277, P = 0.0004) and TVR (HR: 1.889, 95%CI: 1.185-3.011, P = 0.0075), but the rates of death/MI and MACE were not statistically different. All Academic Research Consortium definition stent thrombosis at 9-year were comparable in the two groups. Conclusions During long-term follow-up through nine years, use of DES in patients with large coronary arteries was still associated with significant reductions in the risks of TLR and TVR.
基金Supported by the Natural Science Foundation of Chongqing,No.cstc2019jcyj-msxmX0793.
文摘BACKGROUND Diffuse large B-cell lymphoma(DLBCL)is a common non-Hodgkin lymphoma.The development of immunotherapy greatly improves the patient prognosis but there are some exceptions.Thus,screening for better biomarkers for prognostic evaluation could contribute to the treatment of DLBCL patients.AIM To screen the novel mediators involved in the development of DLBCL.METHODS The GSE60 dataset was applied to identify the differentially expressed genes(DEGs)in DLBCL,and the principal components analysis plot was used to determine the quality of the included samples.The protein-protein interactions were analyzed by the STRING tool.The key hub genes were entered into to the GEPIA database to determine their expressions in DLBCL.Furthermore,these hub gene alterations were analyzed in cBioportal.The UALCAN portal was employed to analyze the expression of the hub genes in different stages of DLBCL.The Estimation of Stromal and Immune cells in Malignant Tumor tissues using Expression data Score was conducted to evaluate the correlation between the gene expression and tumor purity.The gene-gene correlation analysis was conducted in the GEPIA.The stromal score analysis was conducted in TIMER to confirm the correlation between the gene expression and infiltrated stromal cells.The correlation between the indicated genes and infiltration level of cancerassociated fibroblasts(CAFs)was also completed in TIMER with two methods,MCP-Counter and Tumor immune dysfunction and exclusion.The correlation between fibronectin(FN1)protein level and secreted protein acidic and cysteinerich(SPARC)messenger ribonucleic acid expression was confirmed in the cBioportal.RESULTS The top 20 DEGs in DLBCL were identified,and the principal components analysis plot confirmed the quality of the significant DEGs.The pairwise correlation coefficient analysis among all samples showed that these DEGs have a certain co-expression pattern.The DEGs were subjected to STRING to identify the hub genes,alpha-2-macroglobulin(A2M),cathepsin B(CTSB),FN1,matrix metallopeptidase 9(MMP9),and SPARC.The five hub genes were confirmed to be overexpressed in DLBCL.The cBioportal portal detected these five hub genes that had gene alteration,including messenger ribonucleic acid high amplification and missense mutation,and the gene alteration percentages of A2M,FN1,CTSB,MMP9,and SPARC were 5%,8%,5%,2.7%,and 5%,respectively.Furthermore,the five hub genes had a potential positive correlation with tumor stage.The correlation analysis between the five genes and tumor purity confirmed that the five genes were overexpressed in DLBCL and had a positive correlation with the development of DLBCL.More interestingly,the five genes had a significant correlation with the stromal infiltration scores.The correlation analysis between the fives genes and CAFs also showed a significant value,among which the top two genes,FN1 and SPARC,had a remarkable co-expression pattern.CONCLUSION The top DEGs were identified,and the five hub genes were overexpressed in DLBCL.Furthermore,the gene alterations were confirmed and the positive correlation with tumor purity revealed the overexpression of the five genes and close association with the development of DLBCL.More interestingly,the five genes were positively correlated with stromal infiltration,especially in CAFs.The top two genes,FN1 and SPARC,showed a co-expression pattern,which indicates their potential as novel therapeutic targets for DLBCL.
文摘随着深度学习在国内目标检测的不断应用,常规的大、中目标检测已经取得惊人的进步,但由于卷积网络本身的局限性,针对小目标检测依然会出现漏检、误检的问题,以数据集Visdrone2019和数据集FloW-Img为例,对YOLOv7模型进行研究,在网络结构上对骨干网的ELAN模块进行改进,将Focal NeXt block加入到ELAN模块的长短梯度路径中融合来强化输出小目标的特征质量和提高输出特征包含的上下文信息含量,在头部网络引入RepLKDeXt模块,该模块不仅可以取代SPPCSPC模块来简化模型整体结构还可以利用多通道、大卷积核和Cat操作来优化ELAN-H结构,最后引入SIOU损失函数取代CIOU函数以此提高该模型的鲁棒性。结果表明改进后的YOLOv7模型参数量减少计算复杂性降低并在小目标密度高的Visdrone 2019数据集上的检测性能近似不变,在小目标稀疏的FloW-Img数据集上涨幅9.05个百分点,进一步简化了模型并增加了模型的适用范围。