Current status and trends of nosocomial infection in Zhejiang University affiliated Children's Hospital from 2005 to 2014

Objective To investigate the status and trends of nosocomial infection in children’s hospital to provide references for prevention and control of nosocomial infection.Methods The retrospective study was conducted to analyze the data of nosocomial infection at Zhejiang University affiliated Children’s Hospital from 2005 to 2014.

改良局部枸橼酸抗凝在儿童血液滤过的应用

目的探讨透析泵泵注枸橼酸在儿童局部枸橼酸抗凝(RCA)连续性血液滤过(CHF)中的应用。方法回顾性分析2015年9月至2017年1月重庆医科大学附属儿童医院重症监护室49例行RCA-CHF治疗患儿的临床资料,分为传统组20例行RCA-CHF治疗;改良组29例(以透析泵泵注枸橼酸)在连续性血液透析滤过模式下行RCA-CHF治疗。观察输液泵气泡报警、采血不良、出凝血等不良事件,滤器寿命及枸橼酸抗凝常见并发症等发生情况。结果两组气泡报警、滤器寿命比较,差异有统计学意义(P<0.05);两组治疗前后生化指标比较中,Na^+、iCa^(2+)、TCa^(2+)/iCa^(2+)及HCO_3^-比较,差异均有统计学意义(P<0.05),但治疗前、后改良组与传统组Na^+、iCa^(2+)、TCa^(2+)/iCa^(2+)及HCO_3^-比较,差异均无统计学意义(P>0.05)。结论透析泵代替枸橼酸泵的改良技术可以更安全有效地用于儿童RCA-CHF治疗。