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Extracorporeal shock wave therapy in treating ischial non-union following Bernese periacetabular osteotomy:A case report
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作者 Jun Yan Jun-Yu Zhu +6 位作者 Fei-Fei Zhao Jian Xiao Hao Li Ming-Xin Wang Jing Guo Liang Cui Geng-Yan Xing 《World Journal of Orthopedics》 2024年第10期991-996,共6页
BACKGROUND Extracorporeal shock wave therapy(ESWT)is increasingly being recognized as an advantageous alternative for treating non-union due to its efficacy and minimal associated complications.Non-union following Ber... BACKGROUND Extracorporeal shock wave therapy(ESWT)is increasingly being recognized as an advantageous alternative for treating non-union due to its efficacy and minimal associated complications.Non-union following Bernese periacetabular osteotomy(PAO)is particularly challenging,with a reported 55%delayed union and 8%non-union.Herein,we highlight a unique case of ischial non-union post-PAO treated successfully with a structured ESWT regimen.CASE SUMMARY A 50-year-old patient,diagnosed with left ischial non-union following the PAO,underwent six cycles of ESWT treatment across ten months.Each cycle,spaced four weeks apart,consisted of five consecutive ESWT sessions without anesthesia.Regular X-ray follow-ups showed progressive disappearance of the fracture line and fracture union.The patient ultimately achieved a satisfactory asymptomatic recovery and bone union.CONCLUSION The results from this case suggest that this ESWT regimen can be a promising non-invasive treatment strategy for non-union following PAO. 展开更多
关键词 Ischial non-union Extracorporeal shock wave therapy non-union Bernese periacetabular osteotomy Case report
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Early Treatment Outcome of Humeral Shaft Fracture Non-Union in Adults: Comparative Study of Plating versus Interlocking Nailing
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作者 Abdullallahi Bello Galadima Lukman Olalekan Ajiboye +1 位作者 Muhammad Nuhu Salihu Isha Nurudeen 《Health》 2024年第4期371-381,共11页
Background: Fractures of humeral shaft in adults are common injuries. Humeral shafts non-union either from late presentation after initial treatment by traditional bone setters or failed non-operative orthodox care is... Background: Fractures of humeral shaft in adults are common injuries. Humeral shafts non-union either from late presentation after initial treatment by traditional bone setters or failed non-operative orthodox care is a major problem in this part of the world. This non-union is a major treatment challenge with increased cost of care and morbidity in this part of the world. Humeral shaft non-union can be treated with locked intra-medullary nailing (LIMN) or dynamic compression plating (DCP). Study on comparison of these methods of fixation in this part of the world is scarce in literature search, hence the reason for this study. Objective: The objectives of this study are: (1) to compare early clinical outcome following fixation of humeral shaft fracture nonunion with DCP versus LIMN;(2) to compare the time of radiologic fracture union of DCP with LIMN;(3) to compare complications following fixation of humeral shaft fracture nonunion with DCP versus LIMN. Patients and Methods: This was a randomized control study done for 2 years in which fifty adult patients with humeral shaft non-union were recruited. The patients were grouped into 2 (P = DCP & N = LIMN). Forty five of the patients completed the follow up periods of the study and then analyzed. The P group had ORIF with DCP while the N group had ORIF with LIMN. Both groups had grafting with cancellous bones. Each patient was followed up for a period of 6 months at the time which radiographic union is expected. Any patient without clinical and/or radiographic evidence of union after six months of surgery was diagnosed as having recurrent non-union. The data generated was analyzed using SPSS Version 23. The results were presented in charts and tables. The paired t-test was used while considering p value Result: Forty five patients completed follow up. There was a male preponderance (4:1), right humerus predominated (3:2). Motor vehicular accidents were the commonest cause of the fractures (62%). Most non-union fractures occurred at the level of the middle 3<sup>rd</sup> of the humeral shaft (60%). Failed TBS treatment was the commonest indication for the osteosynthesis (71%). More patients had plating (53%) compared to 47% who had LIMN. Most patients (93.4%) had union between 3 to 6 months irrespective of fixation type with no significant statistical difference between the union rate of DCP and LIMN (p value 0.06) with similar functional outcome and complication rates irrespective of the type of fixation. Conclusion: This study showed that the success rates in term of fracture union, outcome functional grades and complication rates were not directly dependent on the types of the fixation: plating or locked intra-medullary nailing. 展开更多
关键词 Humeral Shaft non-union Dynamic Compression Plating Locked Intra-Medullary Nailing Early Treatment Outcome Early Outcome
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Systematic review of dynamization vs exchange nailing for delayed/non-union femoral fractures 被引量:7
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作者 Jacob E Vaughn Ronit V Shah +3 位作者 Tarek Samman Jacob Stirton Jiayong Liu Nabil A Ebraheim 《World Journal of Orthopedics》 2018年第7期92-99,共8页
AIM To analyze the literature on efficacy of dynamamization vs exchange nailing in treatment of delayed and nonunion femur fractures.METHODS Ultimately, 31 peer-reviewed articles with 644 exchanged nailing patients an... AIM To analyze the literature on efficacy of dynamamization vs exchange nailing in treatment of delayed and nonunion femur fractures.METHODS Ultimately, 31 peer-reviewed articles with 644 exchanged nailing patients and 131 dynamization patients were identified and analyzed. The following key words were inputted in different combinations in order to search the field of publications in its entirety: "nonunion", "delayed union", "ununited", "femur fracture", "femoral fracture", "exchange nailing", "dynaiz(s)ation", "secondary nailing", "dynamic", "static", and "nail revision". The initial search yielded over 150 results, and was refined based on the inclusion criteria: Only studies reporting on humans, non-unions and delayed unions, and the usage of exchange nailing and/or dynamization as a secondary treatment after failed IM nailing. The resulting 66 articles were obtained through online journal access. The results were filtered further based on the exclusion criteria: No articles that failed to report overall union rates, differentiate between success rates of their reported techniques, or articles that analyzed less than 5 patients. RESULTS Exchange nailing lead to fracture union in 84.785% of patients compared to the 66.412% of dynamization with statistically comparable durations until union(5.193 ± 2.310 mo and 4.769 ± 1.986 mo respectively). Dynamically locking exchange nails resulted in an average union time of 5.208 ± 2.475 mo compared to 5.149 ± 2.366 mo(P = 0.8682) in statically locked exchange nails. The overall union rate of the two procedures, statically and dynamically locked exchange nailing yielded union rates of 84.259% and 82.381% respectively. Therefore, there was no significant difference between the different locking methods of exchange nailing for union rate or time to union at a significance value of P < 0.05. The analysis showed exchange nailing to be the more successful choice in the treatment of femoral non-unions in respect to its higher success rate(491/567 EN, 24/57 dynam, P < 0.0001). However, there was no significant difference between the success rates of the two procedures for delayed union fractures(25/27 EN, 45/55 dynam, P = 0.3299). Nevertheless, dynamization was more efficient in the treatment of delayed unions(at rates comparable to exchange nailing) than in the treatment of non-unions.CONCLUSION In conclusion, after examination of factors, dynamization is recommended treatment of delayed femur fractures, while exchange nailing is the treatment of choice for non-unions. 展开更多
关键词 non-union DELAYED union DYNAMIZATION FEMORAL fracture EXCHANGE NAILING
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Two-stage surgical treatment for septic non-union of the forearm 被引量:3
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作者 Fabrizio Perna Federico Pilla +4 位作者 Matteo Nanni Lisa Berti Giada Lullini Francesco Traina Cesare Faldini 《World Journal of Orthopedics》 2017年第6期471-477,共7页
AIM To investigate the effectiveness of a two-stage surgical procedure for the treatment of septic forearm non-union.METHODS Septic non-unions are rare complications of forearm fractures. When they occur, they modify ... AIM To investigate the effectiveness of a two-stage surgical procedure for the treatment of septic forearm non-union.METHODS Septic non-unions are rare complications of forearm fractures. When they occur, they modify the relationship between forearm bones leading to a severe functional impairment. Treatment is challenging and surgery and antibiotic therapy are required to achieve infection resolution. It is even harder to obtain non-union healing with good functional results. The aim of this study is to present a two stages surgical treatment for septic forearm non-union with revision and temporary stabilization of the non-union until infection has cleared and subsequently perform a new synthesis with plate, opposite bone graft strut and intercalary graft. We retrospectively reviewed 18 patients with a mean age at the time of primary injury of 34.5 years(19-57 years) and a mean follow-up of 6 years(2-10 years). All patients presented an atrophic nonunion with a mean length of the bone defect of 1.8 cm(1.2-4 cm). Complications and clinical results after surgical treatment were recorded. RESULTS Mean time to resolution of the infectious process was 8.2 wk(range 4-20 wk) after the first surgery and specific antibiotic therapy. All the non-union healed with an average time of 5 mo(range 2-10 mo) after the second step surgery. Cultures on intraoperative samples werepositive in all cases. No major intraoperative complications occurred. Two patients developed minor complications and one needed a second surgical debridement for infection resolution. At the last follow-up functional results were excellent in 5(27.8%) patients, satisfactory in 10(55.5%) and unsatisfactory in 3(16.7%) patients. No activities of daily living(ADLs) limitations were reported by 12(66.6%) patients, slight by 3(16.6%) and severe limitation by 3(16.6%) patients. Mean visual analog scale at the last follow-up was 1(0-3).CONCLUSION The two-step technique has proven to be effective to achieve resolution of the infectious process and union with good functional results and low rate of complications. 展开更多
关键词 FOREARM FRACTURES non-union Delayed UNION Infection Open fracture External fixation Bone GRAFT
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Bone Transport in Tibial Gap Non-Union—A Series of 25 Cases 被引量:1
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作者 Manish Kiran Rabi Jee 《Open Journal of Orthopedics》 2012年第4期144-149,共6页
Gap non-union of the tibia is frequently associated with deformity, infection and shortening. Ilizarov’s method of bone transport was used in the management of twenty-five cases of gap non-union of the tibia. The mea... Gap non-union of the tibia is frequently associated with deformity, infection and shortening. Ilizarov’s method of bone transport was used in the management of twenty-five cases of gap non-union of the tibia. The mean bone gap was 6.53 cm (range 4 to 12 cm). Union was achieved in all cases within a mean period of 11.12 months. The mean time taken for union, per centimeter of bone gap was found to be 1.7 months/cm. Pin tract infection was the commonest complication, seen in 9 cases (36%). The other complications encountered were neuropraxia (n = 3) deviation of the transported bone segment (n = 7), buckling of skin at the advancing side of bone (n = 4), traumatic corticotomy (n = 3), incomplete corticotomy (n = 1), equinus deformity (n = 4), knee stiffness (n = 4) and curling of toes (n = 4). The bone healing results were excellent in 92% of cases and good in 8% of cases. The functional results were excellent in 84% of cases, good in 12% and fair in 4% of cases. Thus bone transport by Ilizarov’s method manages the bone loss and the associated conditions with good bone healing and functional results. 展开更多
关键词 TIBIAL GAP non-union BONE TRANSPORT Ilizarov’s Method
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Long Bone Non-Unions and Malunions: Risk Factors and Treatment Outcomes in Calabar, Southern Nigeria 被引量:1
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作者 Ikpeme A. Ikpeme Nkese E. Mkpanam +2 位作者 Innocent E. Abang Ngim E. Ngim Anthony M. Udosen 《Open Journal of Orthopedics》 2013年第6期253-257,共5页
Background: Diaphyseal non-unions and malunions constitute significant morbidities in fracture care. Fracture treatment modalities seek to restore anatomic orientation and functional rehabilitation as soon as possible... Background: Diaphyseal non-unions and malunions constitute significant morbidities in fracture care. Fracture treatment modalities seek to restore anatomic orientation and functional rehabilitation as soon as possible after a fracture incident. Malunions and non unions present a treatment challenge with the need for prolonged hospitalization, multiple surgical interventions and economic burden. In the developing world, traditional bonesetting practices are popular and these often result in a host of preventable complications. The added socioeconomic costs of treating these complications present a considerable strain on the resources of these already fragile economies and households. Aim: To document the risk factors, treatment options and outcomes for diaphyseal non-unions and malunions in our environment. Patients and Methods: Fifty-two consecutive patients comprising 37 non-unions and 15 malunions who presented in the orthopaedic unit of a tertiary hospital in Southern Nigeria were evaluated. Information sought included biodata, location of pathology, type of incident fracture, local risk factors including traditional bonesetting;treatment options and final outcomes. Information obtained was analyzed using SPSS version 20 (IBM, New York). Results are presented in simple frequency tables. Results: There were 34 males and 18 females (M:F = 1.9:1) with a mean age of 38.76 ± 14.55 years. There were 37 non-unions and 15 malunions. The femur was the commonest site of pathology in 21 (40.4%) cases, and among the non-unions, the atrophic variety was the commonest type (n = 26;70.3%). The mean fracture-to-surgery interval was 11.35 ± 7.95 months and traditional bonesetting was the commonest risk factor (n = 36;69.2%). Plate and screw Osteosynthesis with bonegraft augmentation was the commonest treatment modality and the overall union rate was 94%. Conclusion: Traditional bonesetting plays a major role in the health seeking behaviour of many African societies. The complications are varied and add to the overall socioeconomic burden of fracture care in these developing economies. Identification of traditional bonesetting practices as an important risk factor should translate into a focus on these practices in preventive public health decisions in fracture care. Continuing public health education backed by political will and can potentially drive a paradigm shift in health seeking attitudes in the developing word. 展开更多
关键词 non-union Malunions Traditional Bonesetting Resource-Poor ECONOMY
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Evaluation of bone remodeling in regard to the age of scaphoid non-unions
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作者 Susanne Rein Uwe Hanisch +3 位作者 Hans-Eberhard Schaller Hans Zwipp Stefan Rammelt Stefan Weindel 《World Journal of Orthopedics》 2016年第7期418-425,共8页
AIM: To analyse bone remodeling in regard to the age of scaphoid non-unions(SNU) with immunohistochemistry.METHODS: Thirty-six patients with symptomatic SNU underwent surgery with resection of the pseudarthrosis. The ... AIM: To analyse bone remodeling in regard to the age of scaphoid non-unions(SNU) with immunohistochemistry.METHODS: Thirty-six patients with symptomatic SNU underwent surgery with resection of the pseudarthrosis. The resected material was evaluated histologically after staining with hematoxylin-eosin(HE), tartrate resistant acid phosphatase(TRAP), CD 68, osteocalcin(OC) and osteopontin(OP). Histological examination was performed in a blinded fashion.RESULTS: The number of multinuclear osteoclasts in the TRAP-staining correlated with the age of the SNU and was significantly higher in younger SNU(P = 0.034; r = 0.75). A higher number of OP-immunoreactive osteoblasts significantly correlated with a higher number of OC-immunoreactive osteoblasts(P = 0.001; r = 0.55). Furthermore, a greater number of OP-immunoreactive osteoblasts correlated significantly with a higher number of OP-immunoreactive multinuclear osteoclasts(P = 0.008; r = 0.43). SNU older than 6 mo showed a signifi-cant decrease of the number of fibroblasts(P = 0.04). Smoking and the age of the patients had no influence on bone remodeling in SNU.CONCLUSION: Multinuclear osteoclasts showed a significant decrease in relation to the age of SNU. However, most of the immunhistochemical findings of bone remodeling do not correlate with the age of the SNU. This indicates a permanent imbalance of bone formation and resorption as indicated by a concurrent increase in both osteoblast and osteoclast numbers. A clear histological differentiation into phases of bone remodeling in SNU is not possible. 展开更多
关键词 Bone remodeling HISTOLOGY Immunohistological staining Scaphoid non-union SCAPHOID Wrist joint
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Accordion Manoeuvre with Ilizarov Frame over Nail <i>in Situ</i>in a Case of Infected Non-Union of Femur: Discussion on Strategies: A Case Report
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作者 Ranjit Kr. Baruah 《Open Journal of Orthopedics》 2014年第7期183-188,共6页
Quiescent Type of H. Rosen & Stage 2 of C.L. Romano et al. for Infected Non Union of Femur after K-nailing (Küntscher nailing) require no debridement & removal of nail and therefore can be treated by a si... Quiescent Type of H. Rosen & Stage 2 of C.L. Romano et al. for Infected Non Union of Femur after K-nailing (Küntscher nailing) require no debridement & removal of nail and therefore can be treated by a single stage procedure. There are a few reports of treating aseptic non-union of femur by compression alone or compression distraction over nail by Ilizarov Technique. However, no case of Infected Non-Union femur being treated by Accordion Manoeuvre with Ilizarov over nail in situ (i.e. without exchange nailing) has been reported so far. Here, we are reporting a case of Infected Non-Union following K-nailing for a fracture shaft of femur in a 15-year-old female, who was treated by this technique as a single stage procedure. An Ilizarov frame was mounted on the femur with nail in situ followed by Accordion Manoeuvre. The fracture was healed in 5.6 months with two cycles of Accordion Manoeuvre followed by rhythmic compression. There was no recurrence of infection. 展开更多
关键词 INFECTED non-union FEMUR ACCORDION Manoeuvre by ILIZAROV over NAIL in Situ
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Teriparatide anabolic therapy as potential treatment of type Ⅱ dens non-union fractures
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作者 Enrico Pola Virginia Pambianco +3 位作者 Debora Colangelo Virginia M Formica Giovanni Autore Luigi A Nasto 《World Journal of Orthopedics》 2017年第1期82-86,共5页
Odontoid fractures account for 5% to 15% of all cervical spine injuries and 1% to 2% of all spine fractures. Type Ⅱ fractures are the most common fracture pattern in elderly patients. Treatment(rigid and non-rigid im... Odontoid fractures account for 5% to 15% of all cervical spine injuries and 1% to 2% of all spine fractures. Type Ⅱ fractures are the most common fracture pattern in elderly patients. Treatment(rigid and non-rigid immobilization, anterior screw fixation of the odontoid and posterior C1-C2 fusion) remains controversial and represents a unique challenge for the treating surgeon. The aims of treatment in the elderly is to quickly restore pre-injury function while decreasing morbidity and mortality associated with inactivity, immobilization with rigid collar and prolonged hospitalization. Conservative treatment of type Ⅱ odontoid fractures is associated with relatively high rates of non-union and in a few cases delayed instability. Options for treatment of symptomatic non-unions include surgical fixation or prolonged rigid immobilization. In this report we present the case of a 73-year-old woman with post-traumatic odontoid nonunion successfully treated with Teriparatide systemic anabolic therapy. Complete fusion and resolution of the symptoms was achieved 12 wk after the onset of the treatment. Several animal and clinical studies have confirmed the potential role of Teriparatide in enhancing fracture healing. Our case suggests that Teriparatide may have a role in improving fusion rates of C2 fractures in elderly patients. 展开更多
关键词 Type odontoid fractures non-union Anabolic therapy TERIPARATIDE Fracture healing
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Implementation of the Masquelet Technique in Complicated Septic Non-union of the Ulna A Case Report
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作者 Christos K. Kyriakopoulos Ioannis K. Trintafyllopoulos +1 位作者 Thomas A. Kostakos Athanasios T. Kostakos 《Journal of Pharmacy and Pharmacology》 2016年第7期293-297,共5页
Abstract: Long bone septic non-union by MRSA (methicillin-resistant Staphylococcus aureus) is always a challenge for the orthopaedic society. Traditional treatment options include distraction osteogenesis methods a... Abstract: Long bone septic non-union by MRSA (methicillin-resistant Staphylococcus aureus) is always a challenge for the orthopaedic society. Traditional treatment options include distraction osteogenesis methods and vascularised bone grafting. These techniques require a high level of expertise and are frequently involved with a variety of side effects or complications. We present a rare case of ulnar fracture complicated by MRSA infection that led to septic non-union. We treated the septic non union with the technique of induced membrane formation (Masquelet technique). A 33 year old male presented to the outpatient clinic, 2 months after internal fixation of a Gustillo I fracture of the left forearm. There was pus discharge from the operative wound and specimen culture was positive for MRSA. Initially the patient received conservative treatment with antibiotics for a period of one month. However, the patient returned with the same clinical presentation. The patient was then treated with hardware removal of the ulna and debridement of the septic non-union. The formed 5 cm bone defect was filled with cement spacer and the ulnar bone was fixed with external fixation. Eight weeks later, the spacer was removed and the bone gap was filled with autologous cancellous bone graft from iliac crest. Five months after grafting, the patient was reviewed. No clinical or functional problems were noted and osseous consolidation of the ulnar bone was confirmed in plain x-rays. The Masquelet technique is a promising alternative treatment for the management of infected long bone non-unions of the upper extremity. 展开更多
关键词 Septic non-union bone defect masquelet technique.
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Non-steroidal anti-inflammatory drugs in postoperative hand fracture management:Do they positively or negatively impact recovery?
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作者 Andrew Gorgy Jacqueline Dalfen +1 位作者 Natasha Barone Johnny Ionut Efanov 《World Journal of Clinical Cases》 SCIE 2024年第21期4856-4858,共3页
This editorial explores the impact of non-steroidal anti-inflammatory drugs(NSAIDs)on postoperative recovery in hand fracture patients,amidst shifting pain management strategies away from opioids due to their adverse ... This editorial explores the impact of non-steroidal anti-inflammatory drugs(NSAIDs)on postoperative recovery in hand fracture patients,amidst shifting pain management strategies away from opioids due to their adverse effects.With hand fractures being significantly common and postoperative pain management crucial for recovery,the potential of NSAIDs offers a non-addictive pain control alternative.However,the controversy over NSAIDs'effects on bone healing—stemming from their Cyclooxygenase-2 inhibition and associated risks of fracture non-union or delayed union—necessitates further investigation.Despite a comprehensive literature search,the study finds a lack of specific research on NSAIDs in postoperative hand fracture management,highlighting an urgent need for future studies to balance their benefits against possible risks. 展开更多
关键词 Hand fracture Post operative management Non-steroidal anti-inflammatory drugs non-union Bone healing Cyclooxygenase-2 inhibitors Opioid alternatives
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Mesenchymal Stromal Cells and Their Uses in Bio-Regenerative Therapies for Bone and Cartilage: A Review
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作者 Nathan Smernoff 《Open Journal of Regenerative Medicine》 2024年第1期1-19,共19页
Mesenchymal stromal cells (MSCs) are a top candidate for new clinical treatments in the repair of bone and cartilage. In several clinical trials, they have shown reliable, effective, and safe management of inflammatio... Mesenchymal stromal cells (MSCs) are a top candidate for new clinical treatments in the repair of bone and cartilage. In several clinical trials, they have shown reliable, effective, and safe management of inflammation, pain, and the regenerative capabilities of resident tissues. MSCs are likely derived from pericytes. They modulate the environment they are placed in by secreting immunomodulatory and signaling molecules to reduce inflammation and direct resident cells to create new tissues. They are easily isolated from several different adult tissues, and inexpensive to grow in a lab. However, a mistake made in the initial classification of MSCs as stem cells has created deeply engrained misconceptions that are still evident today. MSCs are not stem cells, despite a large fraction of research and therapies using the name “mesenchymal stem cells”. This mistake creates false narratives attributing the observed positive outcomes of MSC treatments to stem cell characteristics, which has led to distrust in MSC research. Despite inconsistencies in their classification, MSCs demonstrate consistent positive effects in numerous animal studies and human clinical trials for non-unions and osteoarthritis. With an aging population, regenerative techniques are very promising for novel therapies. To produce trusted and safe new treatments using MSCs, it is essential for the International Society for Cellular Therapies to re-establish common ground in the identity, mechanism of action, and isolation techniques of these cells. 展开更多
关键词 Mesenchymal Stromal Cells OSTEOARTHRITIS non-unions
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自适应特征融合与cosIoU-NMS的目标检测算法 被引量:1
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作者 马素刚 李宁博 +2 位作者 彭冠升 杨小宝 侯志强 《计算机辅助设计与图形学学报》 EI CSCD 北大核心 2024年第1期112-121,共10页
针对经典的有锚框检测算法RetinaNet、无锚框检测算法FCOS等目标检测算法中存在漏检以及重复检测的问题,提出一种自适应特征融合与cosIoU-NMS的目标检测算法.首先采用自适应特征融合模块对多尺度特征中相邻3层特征加权融合,获取丰富的... 针对经典的有锚框检测算法RetinaNet、无锚框检测算法FCOS等目标检测算法中存在漏检以及重复检测的问题,提出一种自适应特征融合与cosIoU-NMS的目标检测算法.首先采用自适应特征融合模块对多尺度特征中相邻3层特征加权融合,获取丰富的上下文信息和空间信息;然后采用cosIoU计算检测框之间的余弦相似度与重叠面积,使目标定位更准确;最后使用cosIoU-NMS代替Greedy-NMS抑制置信度分数较高的冗余框,保留更准确的检测结果.以RetinaNet和FCOS为基准,在PASCAL VOC数据集上的实验结果表明,所提算法的检测精度达到81.3%和82.3%,分别提升2.8个百分点和1.2个百分点;在MSCOCO数据集上检测精度达到36.8%和38.0%,分别提升1.0个百分点和0.7个百分点;该算法能够增强特征表征能力,筛除多余的检测框,有效地提高检测性能. 展开更多
关键词 深度学习 目标检测 多尺度特征融合 交并比 非极大值抑制 余弦相似度
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非托管紧密型医联体构建实践及启示 被引量:1
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作者 王建炜 范阳东 +5 位作者 谭三智 欧阳明 伍军华 吴明珠 彭敏 曹杰 《广州医药》 2024年第5期572-576,共5页
医联体是分级诊疗制度建设的重要抓手,对“健康中国”战略目标的实现具有重要作用。在当前医疗改革背景下,探究医联体建设模式具有重要意义。文章介绍了广州市属A医院和区属B医院探索的非托管紧密型医联体实践举措、成效、创新与不足,... 医联体是分级诊疗制度建设的重要抓手,对“健康中国”战略目标的实现具有重要作用。在当前医疗改革背景下,探究医联体建设模式具有重要意义。文章介绍了广州市属A医院和区属B医院探索的非托管紧密型医联体实践举措、成效、创新与不足,总结了该模式对我国医联体建设的启示:一是政府层面要做好顶层设计,给与政策支持;二是网顶医院要下沉优质资源,因地制宜帮扶;三是成员单位要主动参与建设,抓住发展机遇。 展开更多
关键词 非托管 紧密型 医联体 实践 启示
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带锁髓内钉内固定术与加压钢板内固定术对四肢创伤性骨折后骨不连患者的治疗效果比较
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作者 黄林 黄高峰 +1 位作者 谢钦赐 王金应 《中国现代药物应用》 2024年第17期50-53,共4页
目的 对比四肢创伤性骨折后骨不连采用带锁髓内钉内固定术、加压钢板内固定术进行治疗的效果。方法 选择66例四肢创伤性骨折后骨不连患者,采用随机数字表法分为对照组与观察组,每组33例。对照组患者行加压钢板内固定术治疗,观察组患者... 目的 对比四肢创伤性骨折后骨不连采用带锁髓内钉内固定术、加压钢板内固定术进行治疗的效果。方法 选择66例四肢创伤性骨折后骨不连患者,采用随机数字表法分为对照组与观察组,每组33例。对照组患者行加压钢板内固定术治疗,观察组患者行带锁髓内钉内固定术治疗。比较两组手术疗效、手术指标、术后恢复指标、术后并发症发生情况、运动功能、生活能力和膝关节功能。结果 观察组患者手术优良率90.91%(30/33)高于对照组的63.64%(21/33)(P<0.05)。观察组患者手术用时(131.50±15.50)min、切口长度(15.30±2.50)cm、术后住院时间(10.50±1.50)d、患肢恢复时间(22.05±2.20)周短于对照组的(164.50±16.05)min、(18.30±3.30)cm、(15.50±1.50)d、(35.50±2.50)周,术中出血量(365.50±22.50)ml少于对照组的(453.50±30.60)ml(P<0.05)。观察组患者术后并发症发生率6.06%低于对照组的24.24%(P<0.05)。治疗后,两组患者运动功能、生活能力、膝关节功能评分均高于治疗前,且观察组高于对照组(P<0.05)。结论 带锁髓内钉内固定术治疗四肢创伤性骨折后骨不连具有较高的安全性与有效性,手术损伤小、恢复快,能促进患者运动功能、生活能力、膝关节功能恢复。 展开更多
关键词 带锁髓内钉 加压钢板 内固定术 四肢创伤性骨折 骨不连 手术指标 运动功能 生活能力
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富血小板血浆局部注射治疗手部创面不愈合的临床疗效观察
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作者 金宇晗 《农垦医学》 2024年第2期116-120,共5页
目的:观察手部创面不愈合治疗中富血小板血浆局部注射的临床疗效。方法:回顾性选取2020年2月-2022年2月本院手部创面不愈合患者100例,依据手术彻底清创术后处理方法分为富血小板血浆局部注射治疗组(富血小板血浆组)、常规换药处理组两组... 目的:观察手部创面不愈合治疗中富血小板血浆局部注射的临床疗效。方法:回顾性选取2020年2月-2022年2月本院手部创面不愈合患者100例,依据手术彻底清创术后处理方法分为富血小板血浆局部注射治疗组(富血小板血浆组)、常规换药处理组两组,各50例。统计分析两组疼痛程度、创面愈合情况、瘢痕增生情况、日常自理情况、生活质量、创面生长因子浓度、创面愈合率、创面感染率、临床疗效、换药次数、创面愈合时间、住院时间、住院费用、不良反应发生情况、外观满意度。结果:富血小板血浆组患者的VAS评分、BWAT评分、VSS评分均低于常规换药处理组(P<0.05),ADL评分、SF-36评分、创面VEGF、EGF、TGF-β、PDGF、IGF浓度均高于常规换药处理组(P<0.05),创面愈合率高于常规换药处理组(P<0.05),创面感染率低于常规换药处理组(P<0.05),总有效率高于常规换药处理组(P<0.05),换药次数少于常规换药处理组(P<0.05),创面愈合时间、住院时间均短于常规换药处理组(P<0.05),住院费用低于常规换药处理组(P<0.05),不良反应发生率低于常规换药处理组(P<0.05),外观满意度高于常规换药处理组(P<0.05)。结论:手部创面不愈合治疗中富血小板血浆局部注射的临床疗效较常规换药显著。 展开更多
关键词 手部创面不愈合 常规换药 富血小板血浆 局部注射 创面愈合 不良反应
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新时代福建工会联系引导社会组织服务职工的路径研究
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作者 林美铃 《天津市工会管理干部学院学报》 2024年第2期54-59,共6页
2021年新修改的《工会法》,将工会组织和工会工作的覆盖面进一步扩展到社会组织,这对新时代工会联系引导社会组织服务职工群众工作提出了新的要求。为进一步贯彻落实党中央、福建省委关于加强和改进党的群团工作要求,满足工会工作法治... 2021年新修改的《工会法》,将工会组织和工会工作的覆盖面进一步扩展到社会组织,这对新时代工会联系引导社会组织服务职工群众工作提出了新的要求。为进一步贯彻落实党中央、福建省委关于加强和改进党的群团工作要求,满足工会工作法治化现实需要,在调研的基础上,积极探索社会组织建会入会方式方法,着力破解社会组织中工会组织覆盖不够全面、作用发挥不够充分等问题,以期推动各级工会加强联系引导社会组织的工作力度,在促进社会组织有序参与社会治理、提供社会服务、承担社会责任、提升职工生活品质等方面充分发挥工会的重要作用,进一步维护劳动关系和谐与社会稳定。 展开更多
关键词 工会 联系引导 社会组织 服务职工
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肾连蛋白局部注射治疗大鼠股骨萎缩性骨不连的实验研究
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作者 申林 吴锦生 +5 位作者 战杰 孙鹏 王思夏 马俊伟 邢长泰 刘岳 《实用手外科杂志》 2023年第4期541-543,548,共4页
目的 通过对大鼠股骨干萎缩性骨不连模型区域局部注射肾连蛋白研究其对骨不连的治疗作用。方法 SD大鼠45只随机分为三组:对照组,骨不连模型组和肾连蛋白组,每组15只。术后3周和6周行X线检查,并做放射线检查评分。于术后6周,应用Micro-C... 目的 通过对大鼠股骨干萎缩性骨不连模型区域局部注射肾连蛋白研究其对骨不连的治疗作用。方法 SD大鼠45只随机分为三组:对照组,骨不连模型组和肾连蛋白组,每组15只。术后3周和6周行X线检查,并做放射线检查评分。于术后6周,应用Micro-CT扫描各组大鼠股骨,计算骨体积(Bone volume, BV)、组织体积(Tissue volume, TV)、骨体积分数(BV/TV)。术后6周处死大鼠,取各组大鼠骨折端骨组织进行免疫组织化学,检测CD31、BMP-2、Runx2、OCN和FGFR表达。结果 对照组15只大鼠均发生了股骨骨性愈合。骨不连模型组15只大鼠均成功建立了不愈合模型。肾连蛋白组12只大鼠股骨愈合,3只大鼠股骨出现骨不连。结论 局部应用肾连蛋白可以有效地逆转萎缩性骨不连发生的过程。 展开更多
关键词 肾连蛋白 萎缩性骨不连 成骨细胞 FGFR通路
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从媒体视角管窥我党对《苏德互不侵犯条约》的态度
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作者 贺文乐 《晋中学院学报》 2023年第2期24-28,共5页
20世纪30年代末,国际局势复杂多变。世界各大国基于自身利益的考虑,“战与和”成为争论的焦点。1939年8月《苏德互不侵犯条约》签订后,中国共产党表示支持苏联的此种外交政策。一方面,主流媒体广泛宣传条约的重大意义,另一方面高层领导... 20世纪30年代末,国际局势复杂多变。世界各大国基于自身利益的考虑,“战与和”成为争论的焦点。1939年8月《苏德互不侵犯条约》签订后,中国共产党表示支持苏联的此种外交政策。一方面,主流媒体广泛宣传条约的重大意义,另一方面高层领导发表言论对其表示了一定程度的认同。中国共产党的态度基于多种因素的考虑,其中既有共产国际的影响,又有对苏联援华的乐观估计。此种态度体现了中国共产党对共产国际和苏联信任度的提升,同时在增强中国共产党国际与国内地位方面产生了重要影响,并加快了中国新民主主义革命的历史进程。 展开更多
关键词 媒体视角 中国共产党 《苏德互不侵犯条约》
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基于中心点距离关联的三维多目标跟踪算法 被引量:1
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作者 董艳秋 万旺根 +1 位作者 王旭智 孙学涛 《工业控制计算机》 2023年第12期12-14,共3页
三维多目标跟踪技术在自动驾驶中发挥着重要的作用,许多基于检测的三维多目标跟踪方法被提出。数据关联是多目标跟踪中的关键步骤,基于中心点的检测网络在三维多目标检测上的有效性得到了广泛验证。因此,充分利用检测框与跟踪框之间的... 三维多目标跟踪技术在自动驾驶中发挥着重要的作用,许多基于检测的三维多目标跟踪方法被提出。数据关联是多目标跟踪中的关键步骤,基于中心点的检测网络在三维多目标检测上的有效性得到了广泛验证。因此,充分利用检测框与跟踪框之间的中心点距离信息,在三维多目标跟踪网络中,提出了基于中心点距离交并比(DIoU)的检测预处理以及数据关联优化算法。在公开数据集nuScenes上的实验结果表明,该网络与其他方法相比,在自行车、汽车以及行人等类别的平均跟踪精度上有明显提升,在ID切换次数上有较好的抑制效果。 展开更多
关键词 三维多目标跟踪 数据关联 交并比 非极大值抑制
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