This article deals with the introduction and explanation of the two nuéeardentes of “Mue’el Valley” and “Shirvandareh Valley” which are one type of the pyroclastic flows of Sabalan volcano. One of the featur...This article deals with the introduction and explanation of the two nuéeardentes of “Mue’el Valley” and “Shirvandareh Valley” which are one type of the pyroclastic flows of Sabalan volcano. One of the features of nuéeardente in these two valleys is the presence of large blocks in upstream of valley and the abundance of ash in downstream which it has happened in one stage in Mue’el and in several stages in Shirvandareh Valley. Considering the antiquity of the great Sabalan volcano and numerous changes that have happened during these long years in the region, determining the temperature of nuéeardente was impossible. But what could be mentioned as a sign of high temperature because of nuéeardente is the presence of rust ground mass on piece levels which indicate hot water steam (500°C to 600°C). Also puzzle breakings like those in these rocks should be the result of severe explosion blast and very fast movements of nuéeardente that has broken these rocks instantly. These nuéeardentes are peléan type and they are more or less synchronous, and the main reason could be the huge explosion which happened because of the second caldra’s subsidence. By comparing deposits of the two nuéeardentes of Mue’el Valley and Shirvandareh Valley, it is observed that the extent, thickness, and size of blocks are higher in Shirvandareh than those in Mue’el Valley. Also considering higher levels of pieces’ adherence and hardness of deposits, it can be concluded that the temperature of this complex was higher than that of Mue’el Valley, and in general the power of Shirvandareh’s nuéeardente is more than the Mue’el Valley’s.展开更多
目的探讨人前列腺癌细胞系DU145细胞中肝X受体(liver X receptor,LXR)特异性激动剂GW3965对核受体结合蛋白1(nuclear receptor binding protein 1,NRBP1)的表达调控作用。方法采用MTT法检测不同浓度GW3965(浓度分别为0.5、5、10μmol/L...目的探讨人前列腺癌细胞系DU145细胞中肝X受体(liver X receptor,LXR)特异性激动剂GW3965对核受体结合蛋白1(nuclear receptor binding protein 1,NRBP1)的表达调控作用。方法采用MTT法检测不同浓度GW3965(浓度分别为0.5、5、10μmol/L)作用24 h后对DU145细胞增殖的影响。在人前列腺癌DU145细胞中用LXR的特异性激动剂GW3965处理24 h后,经逆转录-聚合酶链反应(RT-PCR)检测LXR特异性靶基因三磷腺苷结合A1(ATP-bindingcassette A1,ABCA1)转录水平的表达情况;随后在转录水平和翻译水平检测NRBP1的表达。结果 LXR特异性激动剂GW3965各实验组对细胞的活性和增殖无影响(P>0.05)。GW3965作用于DU145细胞后,ABCA1转录水平呈剂量依赖性升高,表明LXR在DU145细胞中具有功能活性。LXR经过活化后在转录和翻译水平对NRBP1的抑制作用呈剂量依赖性降低。结论 LXR在DU145细胞中可抑制NRBP1的表达。展开更多
文摘This article deals with the introduction and explanation of the two nuéeardentes of “Mue’el Valley” and “Shirvandareh Valley” which are one type of the pyroclastic flows of Sabalan volcano. One of the features of nuéeardente in these two valleys is the presence of large blocks in upstream of valley and the abundance of ash in downstream which it has happened in one stage in Mue’el and in several stages in Shirvandareh Valley. Considering the antiquity of the great Sabalan volcano and numerous changes that have happened during these long years in the region, determining the temperature of nuéeardente was impossible. But what could be mentioned as a sign of high temperature because of nuéeardente is the presence of rust ground mass on piece levels which indicate hot water steam (500°C to 600°C). Also puzzle breakings like those in these rocks should be the result of severe explosion blast and very fast movements of nuéeardente that has broken these rocks instantly. These nuéeardentes are peléan type and they are more or less synchronous, and the main reason could be the huge explosion which happened because of the second caldra’s subsidence. By comparing deposits of the two nuéeardentes of Mue’el Valley and Shirvandareh Valley, it is observed that the extent, thickness, and size of blocks are higher in Shirvandareh than those in Mue’el Valley. Also considering higher levels of pieces’ adherence and hardness of deposits, it can be concluded that the temperature of this complex was higher than that of Mue’el Valley, and in general the power of Shirvandareh’s nuéeardente is more than the Mue’el Valley’s.
