In the experiment, the brown rice whose moisture content was 12.5% was used as raw material. The brown rice was grouped, then moisturized differently and milled. While milling, the energy consumption, the rate of brok...In the experiment, the brown rice whose moisture content was 12.5% was used as raw material. The brown rice was grouped, then moisturized differently and milled. While milling, the energy consumption, the rate of broken rice and the crack rate were tested. It is confirmed that the stress crack owing to the moisture added to the brown rice can be avoided when the moisture amount added once is limited to no more than 1.5%. It is also proved that the energy consumption can be reduced, the yielding rate of rice can be increased and that the quality of rice can be improved.展开更多
针对基于You Only Look Once v2算法的目标检测存在精度低及稳健性差的问题,提出一种车辆目标实时检测的You Only Look Once v2优化算法;该算法以You Only Look Once v2算法为基础,通过增加网络深度,增强特征提取能力,同时,通过添加残...针对基于You Only Look Once v2算法的目标检测存在精度低及稳健性差的问题,提出一种车辆目标实时检测的You Only Look Once v2优化算法;该算法以You Only Look Once v2算法为基础,通过增加网络深度,增强特征提取能力,同时,通过添加残差模块,解决网络深度增加带来的梯度消失或弥散问题;该方法将网络结构中低层特征与高层特征进行融合,提升对小目标车辆的检测精度。结果表明,通过在KITTI数据集上进行测试,优化后的算法在检测速度不变的情况下,提高了车辆目标检测精度,平均精度达到0.94,同时提升了小目标检测的准确性。展开更多
New once daily mesalamine formulations may improve adherence to medication usage.Response to Asacol and other forms of 5-aminosalicyclic acid(5-ASA)is better correlated with tissue concentrations and best predicted by...New once daily mesalamine formulations may improve adherence to medication usage.Response to Asacol and other forms of 5-aminosalicyclic acid(5-ASA)is better correlated with tissue concentrations and best predicted by concentrations of the drug within the lumen of the colon.Our group used computer simulation to predict colonic 5-ASA levels after Asacol administration.In our study,the model simulated Asacol distribution in the healthy colon,and during quiescent and active ulcerative colitis.An Asacol dosage of 800 mg,threetimes a day,was compared to 2400 mg given once a day.Under ideal conditions,the predicted maximum drug in the total colon and individual colonic segments over 100 d differed by less than 3%between single and multiple doses.Despite changes in motility and defection rates,the predicted maximum and average 5-ASA concentrations in the total colon and individual colonic segments differed by less than 10%between dosing regimens.Asymmetric distribution of 5-ASA in the colon was influenced by frequency of bowel movements and colonic transit rate.In active colitis,sigmoid 5-ASA concentration becomes negligible.Our model supports once daily administration of Asacol as standard treatment for ulcerative colitis.展开更多
The antifreeze critical strength and the pre-curing time of low-temperature concrete were studied by means of guaranteed rate of compressive strength and antifreeze performance for the structural safety requirement of...The antifreeze critical strength and the pre-curing time of low-temperature concrete were studied by means of guaranteed rate of compressive strength and antifreeze performance for the structural safety requirement of concrete engineering,suffering once freeze damage under air environment.It is shown that the antifreeze critical strength is 3.7-4.4MPa,pre-curing time is 18-32 h by guaranteed rate of compressive strength,and the antifreeze critical strength is 3.7-4.4MPa,pre-curing time is 18-32 h by guaranteed rate of antifreeze performance.It can be found that the method of guaranteed rate of compressive strength is sensitive to the defect which generated by freeze damage in the concrete interior.The method is fit to evaluate the antifreeze critical strength of low-temperature concrete.展开更多
Once more to the lake is a representative work of the American Writer, Elwyn Brooks White, and has been acclaimed by people in the world. The paper offers a three-layered contrasting analysis of the essay. By detailed...Once more to the lake is a representative work of the American Writer, Elwyn Brooks White, and has been acclaimed by people in the world. The paper offers a three-layered contrasting analysis of the essay. By detailed analysis of the contrasts running through the whole essay, the author finds that those contrasts are symbol of White's internal struggle and reflection for life.On the foundation of the three-layered contrasts, the paper presents the theme analysis and clarifies the content of the essay.展开更多
This paper provides a new sorting algorithm called 'Only-Once-Sorting' algorithm a mathemati cal formula,this algorithm can put elements in the positions they should be stored only once,then compacts them.The ...This paper provides a new sorting algorithm called 'Only-Once-Sorting' algorithm a mathemati cal formula,this algorithm can put elements in the positions they should be stored only once,then compacts them.The algorithm completes sorting a sequence of n elements in a calculation time of O(n ).展开更多
In this paper both processes of landslide and subsidence are considered to be limited systems. Each of these systems in nature might be regarded as an organism. Generally their lifespan must develop with common ecolog...In this paper both processes of landslide and subsidence are considered to be limited systems. Each of these systems in nature might be regarded as an organism. Generally their lifespan must develop with common ecological characteristics, including several evolutional stages, such as initiation, growth, maturation, decline and death. Among these stages, maturation is emphasized so as to find the occurring or thriving date of both systems. An once-through cycle of both landslide and subsidence is established and is accurately predicted by a developed, mathematic model of the Poisson cycle. The Weibull distribution is cited for a landslide example. Both fundamentals are discussed. Stage predictions of landslide and subsidence are performed for several examples. Back analysis of landslides that have already happened are studied with the same model. And when compared with results from the biological mathematic model and with practical results, it is found that they correspond. Stage prediction of subsidences is also researched by the principle of the Poisson cycle.展开更多
Non-adherence to immunosuppressive therapy is associated with reduced graft survival. Fifteen long-term follow up kidney transplant patients with stable post-transplant clinical courses were enrolled in the study. All...Non-adherence to immunosuppressive therapy is associated with reduced graft survival. Fifteen long-term follow up kidney transplant patients with stable post-transplant clinical courses were enrolled in the study. All patients were prescribed to tacrolimus prolonged release, mycophenolate mofetil (MMF) and corticosteroid at the time of enrolment. Twice-daily administration of MMF was then converted to a single daily dose. As a result, all immunosuppressive agents were administered simultaneously at one time in the morning. The daily total doses of the three immunosuppressants were identical during the study period. No acute rejection or adverse event was observed during the study period. Blood urea nitrogen and estimated glomerular filtration rate did not change significantly after conversion to once-daily administration. The blood tacrolimus trough level and the Mycophenolic acid (MPA) trough level also did not change significantly after conversion to once-daily administration. Interestingly, the meanmedian MPA trough level remained >3 μg/ml even after conversion to once-daily administration. A sufficient plasma MPA level was maintained after conversion to once-daily administration, and no acute rejection was observed during the study period. To our knowledge, this study is the first to report that the plasma MPA concentration can be maintained after once-daily administration of MMF in long-term kidney transplant patients. Once-daily administration of immunosuppressive agents may improve long-term graft survival because of better treatment adherence due to the reduced dosing frequency. The safety or efficacy of conversion to once-daily administration of MMF should be evaluated in a future randomized controlled large-scale clinical study.展开更多
Osteonecrosis of the jaw (ONJ) is an adverse effect of nitrogen-containing bisphosphonates. Advancing age, intravenous administration of zoledronic acid (ZOL), history of dento-alveolar surgery, and concomitant system...Osteonecrosis of the jaw (ONJ) is an adverse effect of nitrogen-containing bisphosphonates. Advancing age, intravenous administration of zoledronic acid (ZOL), history of dento-alveolar surgery, and concomitant systemic diseases such as diabetes are known as risk factors for developing ONJ. However, despite numerous studies, the exact pathophysiology remains unclear and management strategies are largely anecdotal. Once-yearly intravenously administered 5 mg ZOL was approved by the US Food and Drug Administration in 2007 for the treatment of osteoporosis and its efficacy with 3 year-regimen had been recently proven in preventing new clinical fracture. Although occurrences of ONJ have been reported to be rare with this drug administration, available data is very limited and long-term outcomes are lacking. We present a case of ONJ identified in an osteopenic patient with an intermittent but long standing sore mouth related to exposed mandibular bone. Once-yearly infusion of zoledronic acid used in the treatment of osteopenia may contribute to the spontaneous development of ONJ, especially in those presenting with multiple comorbidity factors. This report suggests the importance of health care professionals keeping abreast of new developments in this area and providing appropriate information to their patients.展开更多
目标检测是计算机视觉领域的研究热点和基础任务,其中基于锚点(Anchor)的目标检测已在众多领域得到广泛应用。当前锚点选取方法主要面临两个问题:基于特定数据集的先验取值尺寸固定、面对不同场景泛化能力弱。计算锚框的无监督K-means算...目标检测是计算机视觉领域的研究热点和基础任务,其中基于锚点(Anchor)的目标检测已在众多领域得到广泛应用。当前锚点选取方法主要面临两个问题:基于特定数据集的先验取值尺寸固定、面对不同场景泛化能力弱。计算锚框的无监督K-means算法,受初始值影响较大,对目标尺寸较单一的数据集聚类产生的锚点差异较小,无法充分体现网络多尺度输出的特点。针对上述问题,本文提出一种基于多尺度的目标检测锚点构造方法(multi-scale-anchor,MSA),将聚类产生的锚点根据数据集本身的特性进行尺度的缩放和拉伸,优化的锚点即保留原数据集的特点也体现了模型多尺度的优势。另外,本方法应用在训练的预处理阶段,不增加模型推理时间。最后,选取单阶段主流算法YOLO(You Only Look Once),在多个不同场景的红外或工业场景数据集上进行丰富的实验。结果表明,多尺度锚点优化方法MSA能显著提高小样本场景的检测精度。展开更多
针对无人机航拍图像目标检测中视野变化大、时空信息复杂等问题,文中基于YOLOv5(You Only Look Once Version5)架构,提出基于图像低维特征融合的航拍小目标检测模型.引入CA(Coordinate Attention),改进MobileNetV3的反转残差块,增加图...针对无人机航拍图像目标检测中视野变化大、时空信息复杂等问题,文中基于YOLOv5(You Only Look Once Version5)架构,提出基于图像低维特征融合的航拍小目标检测模型.引入CA(Coordinate Attention),改进MobileNetV3的反转残差块,增加图像空间维度信息的同时降低模型参数量.改进YOLOv5特征金字塔网络结构,融合浅层网络中的特征图,增加模型对图像低维有效信息的表达能力,进而提升小目标检测精度.同时为了降低航拍图像中复杂背景带来的干扰,引入无参平均注意力模块,同时关注图像的空间注意力与通道注意力;引入VariFocal Loss,降低负样本在训练过程中的权重占比.在VisDrone数据集上的实验验证文中模型的有效性,该模型在有效提升检测精度的同时明显降低复杂度.展开更多
针对现有混凝土构件裂缝人工检测操作不仅费时、费力,而且易出现错检、误检、漏检,以及部分位置难以开展检测的问题,提出一种基于深度学习YOLOX(You Only Look Once)算法的混凝土构件裂缝智能化检测方法;首先采集、整理包含各类混凝土...针对现有混凝土构件裂缝人工检测操作不仅费时、费力,而且易出现错检、误检、漏检,以及部分位置难以开展检测的问题,提出一种基于深度学习YOLOX(You Only Look Once)算法的混凝土构件裂缝智能化检测方法;首先采集、整理包含各类混凝土构件的典型裂缝图像,并通过图像数据增强建立Pascal VOC数据集,然后基于Facebook公司开发的深度学习框架Pytorch,利用数据集训练YOLOX算法,并进行裂缝识别和验证;将训练完成后YOLOX算法移植至搭载安卓系统的手机端,进行现场实时检测操作。结果表明:在迭代次数为700时,混凝土构件裂缝识别精度可达88.84%,能有效筛分混凝土构件表面裂缝,并排除其他干扰项,证明了所提出的方法对裂缝具有较高的识别精度和广泛的适用性;经试验测试,移植至手机端的YOLOX算法能在提升便携性的同时保证高效、准确的检测效果,具有良好的应用前景。展开更多
为解决交通道路小目标检测难度大、精度低,容易出现错检漏检的问题,提出一种基于YOLO v5(you only look once v5)算法的多尺度特征融合目标检测改进算法。首先,增加小目标检测头用于适应小目标尺寸,缓解漏检情况。然后,引入可变形卷积网...为解决交通道路小目标检测难度大、精度低,容易出现错检漏检的问题,提出一种基于YOLO v5(you only look once v5)算法的多尺度特征融合目标检测改进算法。首先,增加小目标检测头用于适应小目标尺寸,缓解漏检情况。然后,引入可变形卷积网络v2(deformable convolutional networks V2,DCN V2)提高模型对运动中小目标的学习能力;同时,增加上下文增强模块,提升对远距离小目标的识别能力。最后,在替换损失函数、提高边界框定位精度的同时,使用空间金字塔池化和上下文空间金字塔卷积分组模块,提高网络的感受野和特征表达能力。实验结果表明,所提算法在KITTI数据集小目标类别上平均识别精度达到了95.2%,相较于原始YOLO v5,算法总体平均识别精度提升了2.7%,对小目标的检测效果更佳,平均识别精度提升了3.1%,证明所提算法在道路小目标检测方面的有效性。展开更多
基金Tenth Eive-Year Plan of the Committee of the Scientific Tech. of Heilongjiang Province (GB02B4040-1)Heilongjiang Education Bureau (10511012)
文摘In the experiment, the brown rice whose moisture content was 12.5% was used as raw material. The brown rice was grouped, then moisturized differently and milled. While milling, the energy consumption, the rate of broken rice and the crack rate were tested. It is confirmed that the stress crack owing to the moisture added to the brown rice can be avoided when the moisture amount added once is limited to no more than 1.5%. It is also proved that the energy consumption can be reduced, the yielding rate of rice can be increased and that the quality of rice can be improved.
文摘针对基于You Only Look Once v2算法的目标检测存在精度低及稳健性差的问题,提出一种车辆目标实时检测的You Only Look Once v2优化算法;该算法以You Only Look Once v2算法为基础,通过增加网络深度,增强特征提取能力,同时,通过添加残差模块,解决网络深度增加带来的梯度消失或弥散问题;该方法将网络结构中低层特征与高层特征进行融合,提升对小目标车辆的检测精度。结果表明,通过在KITTI数据集上进行测试,优化后的算法在检测速度不变的情况下,提高了车辆目标检测精度,平均精度达到0.94,同时提升了小目标检测的准确性。
文摘New once daily mesalamine formulations may improve adherence to medication usage.Response to Asacol and other forms of 5-aminosalicyclic acid(5-ASA)is better correlated with tissue concentrations and best predicted by concentrations of the drug within the lumen of the colon.Our group used computer simulation to predict colonic 5-ASA levels after Asacol administration.In our study,the model simulated Asacol distribution in the healthy colon,and during quiescent and active ulcerative colitis.An Asacol dosage of 800 mg,threetimes a day,was compared to 2400 mg given once a day.Under ideal conditions,the predicted maximum drug in the total colon and individual colonic segments over 100 d differed by less than 3%between single and multiple doses.Despite changes in motility and defection rates,the predicted maximum and average 5-ASA concentrations in the total colon and individual colonic segments differed by less than 10%between dosing regimens.Asymmetric distribution of 5-ASA in the colon was influenced by frequency of bowel movements and colonic transit rate.In active colitis,sigmoid 5-ASA concentration becomes negligible.Our model supports once daily administration of Asacol as standard treatment for ulcerative colitis.
基金Funded by the National Key Technology R&D Program of China for the 11th Five-Year Plan(2006BAJ04A04)the Natural Science Foundation Project of Liaoning Province(20082008)the Nationd Natural Science Foundation of China(51072122)
文摘The antifreeze critical strength and the pre-curing time of low-temperature concrete were studied by means of guaranteed rate of compressive strength and antifreeze performance for the structural safety requirement of concrete engineering,suffering once freeze damage under air environment.It is shown that the antifreeze critical strength is 3.7-4.4MPa,pre-curing time is 18-32 h by guaranteed rate of compressive strength,and the antifreeze critical strength is 3.7-4.4MPa,pre-curing time is 18-32 h by guaranteed rate of antifreeze performance.It can be found that the method of guaranteed rate of compressive strength is sensitive to the defect which generated by freeze damage in the concrete interior.The method is fit to evaluate the antifreeze critical strength of low-temperature concrete.
文摘Once more to the lake is a representative work of the American Writer, Elwyn Brooks White, and has been acclaimed by people in the world. The paper offers a three-layered contrasting analysis of the essay. By detailed analysis of the contrasts running through the whole essay, the author finds that those contrasts are symbol of White's internal struggle and reflection for life.On the foundation of the three-layered contrasts, the paper presents the theme analysis and clarifies the content of the essay.
文摘This paper provides a new sorting algorithm called 'Only-Once-Sorting' algorithm a mathemati cal formula,this algorithm can put elements in the positions they should be stored only once,then compacts them.The algorithm completes sorting a sequence of n elements in a calculation time of O(n ).
基金The paper is one part of a project supported by National Education Committee Funds for Doctoral Faculty
文摘In this paper both processes of landslide and subsidence are considered to be limited systems. Each of these systems in nature might be regarded as an organism. Generally their lifespan must develop with common ecological characteristics, including several evolutional stages, such as initiation, growth, maturation, decline and death. Among these stages, maturation is emphasized so as to find the occurring or thriving date of both systems. An once-through cycle of both landslide and subsidence is established and is accurately predicted by a developed, mathematic model of the Poisson cycle. The Weibull distribution is cited for a landslide example. Both fundamentals are discussed. Stage predictions of landslide and subsidence are performed for several examples. Back analysis of landslides that have already happened are studied with the same model. And when compared with results from the biological mathematic model and with practical results, it is found that they correspond. Stage prediction of subsidences is also researched by the principle of the Poisson cycle.
文摘Non-adherence to immunosuppressive therapy is associated with reduced graft survival. Fifteen long-term follow up kidney transplant patients with stable post-transplant clinical courses were enrolled in the study. All patients were prescribed to tacrolimus prolonged release, mycophenolate mofetil (MMF) and corticosteroid at the time of enrolment. Twice-daily administration of MMF was then converted to a single daily dose. As a result, all immunosuppressive agents were administered simultaneously at one time in the morning. The daily total doses of the three immunosuppressants were identical during the study period. No acute rejection or adverse event was observed during the study period. Blood urea nitrogen and estimated glomerular filtration rate did not change significantly after conversion to once-daily administration. The blood tacrolimus trough level and the Mycophenolic acid (MPA) trough level also did not change significantly after conversion to once-daily administration. Interestingly, the meanmedian MPA trough level remained >3 μg/ml even after conversion to once-daily administration. A sufficient plasma MPA level was maintained after conversion to once-daily administration, and no acute rejection was observed during the study period. To our knowledge, this study is the first to report that the plasma MPA concentration can be maintained after once-daily administration of MMF in long-term kidney transplant patients. Once-daily administration of immunosuppressive agents may improve long-term graft survival because of better treatment adherence due to the reduced dosing frequency. The safety or efficacy of conversion to once-daily administration of MMF should be evaluated in a future randomized controlled large-scale clinical study.
文摘Osteonecrosis of the jaw (ONJ) is an adverse effect of nitrogen-containing bisphosphonates. Advancing age, intravenous administration of zoledronic acid (ZOL), history of dento-alveolar surgery, and concomitant systemic diseases such as diabetes are known as risk factors for developing ONJ. However, despite numerous studies, the exact pathophysiology remains unclear and management strategies are largely anecdotal. Once-yearly intravenously administered 5 mg ZOL was approved by the US Food and Drug Administration in 2007 for the treatment of osteoporosis and its efficacy with 3 year-regimen had been recently proven in preventing new clinical fracture. Although occurrences of ONJ have been reported to be rare with this drug administration, available data is very limited and long-term outcomes are lacking. We present a case of ONJ identified in an osteopenic patient with an intermittent but long standing sore mouth related to exposed mandibular bone. Once-yearly infusion of zoledronic acid used in the treatment of osteopenia may contribute to the spontaneous development of ONJ, especially in those presenting with multiple comorbidity factors. This report suggests the importance of health care professionals keeping abreast of new developments in this area and providing appropriate information to their patients.
文摘目标检测是计算机视觉领域的研究热点和基础任务,其中基于锚点(Anchor)的目标检测已在众多领域得到广泛应用。当前锚点选取方法主要面临两个问题:基于特定数据集的先验取值尺寸固定、面对不同场景泛化能力弱。计算锚框的无监督K-means算法,受初始值影响较大,对目标尺寸较单一的数据集聚类产生的锚点差异较小,无法充分体现网络多尺度输出的特点。针对上述问题,本文提出一种基于多尺度的目标检测锚点构造方法(multi-scale-anchor,MSA),将聚类产生的锚点根据数据集本身的特性进行尺度的缩放和拉伸,优化的锚点即保留原数据集的特点也体现了模型多尺度的优势。另外,本方法应用在训练的预处理阶段,不增加模型推理时间。最后,选取单阶段主流算法YOLO(You Only Look Once),在多个不同场景的红外或工业场景数据集上进行丰富的实验。结果表明,多尺度锚点优化方法MSA能显著提高小样本场景的检测精度。
文摘针对无人机航拍图像目标检测中视野变化大、时空信息复杂等问题,文中基于YOLOv5(You Only Look Once Version5)架构,提出基于图像低维特征融合的航拍小目标检测模型.引入CA(Coordinate Attention),改进MobileNetV3的反转残差块,增加图像空间维度信息的同时降低模型参数量.改进YOLOv5特征金字塔网络结构,融合浅层网络中的特征图,增加模型对图像低维有效信息的表达能力,进而提升小目标检测精度.同时为了降低航拍图像中复杂背景带来的干扰,引入无参平均注意力模块,同时关注图像的空间注意力与通道注意力;引入VariFocal Loss,降低负样本在训练过程中的权重占比.在VisDrone数据集上的实验验证文中模型的有效性,该模型在有效提升检测精度的同时明显降低复杂度.
文摘针对现有混凝土构件裂缝人工检测操作不仅费时、费力,而且易出现错检、误检、漏检,以及部分位置难以开展检测的问题,提出一种基于深度学习YOLOX(You Only Look Once)算法的混凝土构件裂缝智能化检测方法;首先采集、整理包含各类混凝土构件的典型裂缝图像,并通过图像数据增强建立Pascal VOC数据集,然后基于Facebook公司开发的深度学习框架Pytorch,利用数据集训练YOLOX算法,并进行裂缝识别和验证;将训练完成后YOLOX算法移植至搭载安卓系统的手机端,进行现场实时检测操作。结果表明:在迭代次数为700时,混凝土构件裂缝识别精度可达88.84%,能有效筛分混凝土构件表面裂缝,并排除其他干扰项,证明了所提出的方法对裂缝具有较高的识别精度和广泛的适用性;经试验测试,移植至手机端的YOLOX算法能在提升便携性的同时保证高效、准确的检测效果,具有良好的应用前景。