Repeated operations for infiltrative low - grade gliomas without intervening therapy.

OBJECT:Progression of infiltrative low-grade gliomas(LGGs)has been reported previously.The limitations ofsuch studies include diverse histological grading systems,intervening therapy,and the lack of histological confir-mation of malignant tumor progression.The aim of this study was to determine tumor progression in adult patientswith an initial diagnosis of infiltrative LGG who subsequently underwent a repeated operation,but no other inter-vening therapy.The authors examined factors that may be associated with tumor progression.

Surgical spacer placement and proton radiotherapy for unresectable hepatocellular carcinoma

Few potentially curative treatment options exist apart from hepatic resection for patients with huge hepatocellular carcinoma (HCC). Proton radiotherapy is a promising new modality which has an inherent antitumor effect against HCC. However, the application of proton radiotherapy for tumors adjacent to the gastrointestinal tract is restricted because the tolerance dose of the intestine is extremely low. A novel two-step treatment was developed with surgical spacer placement and subsequent proton radiotherapy to administer proton radiotherapy with curative intent. This report presents a case of a patient with a huge unresectable HCC treated by this method who achieved disease-free survival of more than 2 years. This new strategy may potentially be an innovative and standard therapy for unresectable HCC in the near future.

Conventional operation and laser therapy in the treatment of varicose veins

Objective:To evaluate the effectiveness of endovenous laser therapy and conventional thera- py on the varicose of great saphenous vein.Methods:Thirty-two patients received endovenous laser thera- py and 32 patients were operated by conventional therapy(high ligation and stripping).The observation results of great saphenous vein(GSV)were recorded by clinical evaluation and duplex ultrasound examina- tion.And the operating time,intraoperative blood loss,time to become moveable,duration of hospitaliza- tion and degree of feeling pain were compared between the two groups.Results:Compared with conven- tional therapy,laser therapy had good curative effect with less complications and no scars and no pains. There were significant differences between the two groups(P<0.01).Conclusion:Laser therapy for varicose of great saphenous vein is better than the conventional therapy.It deserves to be widely used in clinical treatment.

Technical operation specification for pricking-cupping therapy

Pricking-cupping therapy is a Traditional Chinese Medicine(TCM)nursing technology that can adjust the viscera of the human body,make the meridians smooth,and Yin and Yang balanced mainly by means of relieving heat and detoxification,harmonizing Qi and blood,promoting blood circulation and removing blood stasis,dredging meridians and activating collaterals,reducing swelling and pain,purging heat and calming shock,clearing heat,and opening orifices.Pricking-cupping therapy has a long history and wide application.After thousands of years of development,it has made great progress.They are widely used to treat lumbar disc herniation,herpes zoster,acute arthritis,migraine,and other diseases in China.Through the clinical practice and theoretical exploration of physicians of past dynasties,the therapeutic mechanism and application scope of pricking-cupping therapy have been greatly enriched.Modern TCM practitioners have conducted in-depth researches on the operation norms of the therapy on the basis of the ancients,hoping to grasp the essence of the disease more accurately and make the rational use of the operation technology of the therapy.

Comparison of Physical Therapy Follow-Up of Patients with Operated and Non-Operated Lumbar Spinal Stenosis According to the Nottingham Health Profile-Pain Scale

Background: Lumbar spinal stenosis (LSS) continues to be a major problem in societies, causing job loss and lowering quality of life. There are two types of treatment methods, physical therapy and surgery. If patients with LSS avoid treatment, they are likely to experience neurological deterioration in later years. Objective: The study aimed to evaluate the effect of physical therapy applied after decompression surgery or the effect of only applied physical therapy in patients with lumbar spinal stenosis. Materials and Methods: The results of the physical therapy follow-up of patients who had surgery and did not have surgery due to lumbar spinal stenosis between July 2014 and December 2019 were compared with each other. All patients received physical therapy for 6 months. Included were 42 patients who underwent decompression surgery due to LSS; 56 patients were not operated. Clinical outcomes were measured using the Nottingham Health Profile-Pain (NHP-Pain) scale at the initial, first, third and sixth months. The results were compared statistically. Results: The age of the operated patients was 54.69 ± 8.42 (39 - 71), while the non-operated patients were 59.16 ± 14.04 (34 - 83). There was no significant difference in the statistical comparison (p = 0.053). While the body mass index (BMI) of the operated patients was 29.43 ± 4.99 (21 - 40), the BMI of the non-operated patients was 28.84 ± 4.62 (22 - 42). There was no significant difference in the statistical comparison (p = 0.552). The scores of a 6-month physical therapy follow-up of patients were evaluated according to the NHP-pain scale. The values of patients who underwent surgery, initial - 1st month (p < 0.001), 1st month - 3rd month (p = 0.028), 3rd month - 6th month (p = 0.389) follow-up of the intervals were compared statistically. The values of non-operated patients, initial - 1st month (p = 0.008), 1st month -3rd month (p = 0.013), 3rd month - 6th month (p = 0.025) were compared statistically. Patients with and without surgery had significantly different initial pain scores (p < 0.001). Conclusions: The NHP-Pain scores of the patients undergoing physical therapy with the operation were shown to provide more significant improvement than the group receiving only the physical therapy. Patients with LSS should be treated with an operation to obtain the maximum benefit of physical therapy.

脑卒中患者采取数字OT训练系统与作业疗法干预对上肢功能和生活自理能力的影响分析

目的:探讨数字OT训练系统与作业疗法在脑卒中疾病中联合应用,对生活自理能力(ADL)评分和上肢功能的影响。方法:选取2020年5月—2021年5月天津市宝坻区人民医院收治的68例脑卒中患者作为研究对象,按照随机数表法分为对照组和观察组,每组各34例。对照组采取作业疗法,观察组采取作业疗法联合数字OT训练系统疗法。对比两组患者康复效果、训练配合度、ADL评分、肢体运动功能(Fugl-Meyer)评分、神经功能(NIHSS)评分、认知功能(MoCA)评分、健康生活质量(SF-36)评分等指标。结果:观察组患者临床康复效果高于对照组,差异有统计学意义(χ^(2)=5.100,P>0.05)。观察组患者训练配合度明显高于对照组,差异有统计学意义(χ^(2)=4.220,P>0.05)。干预后,观察组患者ADL评分、上肢功能评分高于对照组,差异有统计学意义(t=7.035、3.475,P<0.05)。干预后,观察组患者NIHSS评分低于对照组、MoCA评分高于对照组,差异有统计学意义(t=15.561、2.552,P<0.05)。干预后,观察组患者生活质量评分显著高于对照组,差异有统计学意义(t=8.457、7.053、4.750、3.534、7.755、3.782、7.559、4.507,P<0.05)。结论:脑卒中患者采取数字OT训练系统与作业疗法联合干预的效果明显,可改善其认知、神经功能,经合理训练后其上肢功能恢复明显,提升患者日常ADL、生活质量及训练配合度。

OT语法下多元疑问算子移位的类型学视野

基于优选论的分析,通过STAY、FOCUS-MOVE、MLC和T-LICENSE这4个普遍性制约条件的制定和交互作用,可以对疑问句中多元疑问算子在汉语类、英语类、法语类、保加利亚语类和克罗地亚语类这5种类型语言中的移位现象作出统一的解释,从而将此类疑问句的研究统一起来,克服来自生成语法理论解释中的诸多不足,从而更好地体现普遍语法的精神。

桂枝芍药知母汤治疗膝骨性关节炎关节镜清理术后肿痛临床观察

目的探究桂枝芍药知母汤治疗膝骨性关节炎关节镜清理术后肿痛的临床效果。方法选取南昌市洪都中医院收治的膝骨性关节炎关节镜清理术后肿痛患者69例作为研究对象,按随机数字表法分为对照组(34例)和观察组(35例)。对照组予常规治疗,观察组在对照组基础上予桂枝芍药知母汤治疗,比较两组术前及术后1 d、3 d、7 d、14 d视觉模拟量表(VAS)评分、膝关节肿胀值并评估临床疗效。结果术前,两组VAS评分、膝关节肿胀值比较,差异无统计学意义(P>0.05);术后1 d、3 d、7 d、14 d,观察组VAS评分、膝关节肿胀值均低于对照组(P<0.05)。观察组临床治疗总有效率为97.14%(34/35),高于对照组的82.35%(28/34),差异有统计学意义(P<0.05)。结论对膝骨性关节炎关节镜清理术后肿痛患者实施桂枝芍药知母汤治疗,可有效缓解疼痛、消除肿胀,提高临床效果。

靳三针联合站立数字OT训练对脑卒中偏瘫患者上肢运动功能的影响

目的:观察靳三针疗法结合站立数字OT训练对脑卒中后偏瘫患者上肢运动功能的影响。方法:选择2021年1—6月在广东省第二中医院针灸康复科住院部治疗的卒中后上肢偏瘫患者60例,采用随机数字表法分为对照组和观察组,每组30例。2组均接受常规药物治疗和常规康复训练;对照组在常规治疗基础上采用靳三针治疗,选择患肢对侧颞三针、患肢肩三针、手三针(曲池、外关、合谷)、百会、水沟穴进行针刺,以平补平泻手法施针,以患者得气为度,留针30 min,1次/d,6次/周,持续治疗8周;观察组在对照组的基础上接受站立数字OT训练,20 min/次,1次/d,6次/周,持续治疗8周。在干预前、干预8周后采用Fugl-Meyer运动功能评定表上肢部分(FMA-UE)评定上肢运动功能;采用Wolf上肢运动功能评价量表(WMFT)评定上肢运动完成量;采用改良Barthel指数(MBI)评定日常生活活动能力。结果:与治疗前比较,2组治疗后FMA-UE、WMFT、MBI评分均明显升高,差异均具有统计学意义(P<0.05)。与对照组比较,观察组治疗后FMA-UE、WMFT、MBI评分均明显更高,差异均具有统计学意义(P<0.05)。结论:靳三针联合站立数字OT训练能有效地改善脑卒中偏瘫患者上肢运动功能和日常生活活动能力。

Endodontic management of the maxillary first molars with two root canals: A case report and review of the literature

BACKGROUND The complex anatomy of the maxillary first molars has always been a major challenge for complete root canal treatment in endodontic therapy. Here, we present two cases of maxillary first molars, each with only two root canals, which have been rarely reported. We also perform a literature review of maxillary first molar anatomy.CASE SUMMARY The two patients were referred to the hospital after 1) finding a cavity in their tooth with a color change and, 2) a toothache during mastication, respectively.Both of these cases were diagnosed as apical periodontitis by X-ray imaging and cone beam computed tomography(CBCT). Non-surgical endodontic therapy was performed with the assistance of a dental operating microscope(DOM). CBCT showed rare but accurate images of both patients, each with two root canals and two roots in their maxillary first molars. Both roots were located in the buccal in the palatal direction, and each root had only one clear root canal. In addition,each maxillary first molar in both patients was symmetrical to that on the opposing side with only two separate root canals. Non-surgical endodontic therapy was performed with the assistance of a DOM. Finally, the teeth were restored using composite resin and the patients were satisfied with the results.CONCLUSION Making full use of CBCT and DOM would contribute to helping dentists make correct diagnoses and successfully treat teeth with rare root canal morphologies.

Intensify standardized therapy for esophageal and stomach cancer in tumor hospitals

INTRODUCTIONCancer treatment situation in tumor hospitals inChina has its own unique characteristics which arenot found in other parts of the world. Because ofthe huge population and high incidence rates ofesophageal and stomach cancer[1-5], the number ofcancer patients waiting for admission isinconceivably large.

IT/OT融合的全方位理解和实现途径

将对IT/OT融合的关注限定在生产制造的范围可能过于狭窄。应该将其扩展到供应链以及客户需求和响应的上下游,形成一种涵盖供应链和产品生命周期的实时、同步、优化的闭环生态系统。作为工业通信基础架构的信息技术(IT)/操作技术(OT)融合,当务之急是OT网络需要改变多种现场总线和工业以太网并存的局面,采用基于互联网协议(IP)的以太网标准,为与IT网络的融合创造前提。

操作员培训仿真系统(OTS)在某国外项目常压蒸馏装置中的应用

介绍了国外某项目常压蒸馏装置中,操作员培训仿真系统(OTS)的模型结构和在装置开工前期的应用,以及开工后对装置的优化。OTS系统不仅为操作人员提供了一个近似真实生产的培训环境,提高处理突发事故的应变能力,还高精度地模拟了工艺流程和控制方案,验证并完善开工流程,为开工后流程优化打下良好基础。

Controversies in fluid therapy: Type, dose and toxicity

Fluid therapy is perhaps the most common intervention received by acutely ill hospitalized patients; however, a number of critical questions on the efficacy and safety of the type and dose remain. In this review, recent insights derived from randomized trials in terms of fluid type, dose and toxicity are discussed. We contend that the prescription of fluid therapy is context-specific and that any fluid can be harmful if administered inappropriately. When contrasting ‘‘crystalloid vs colloid'', differences in efficacy are modest but differences in safety are significant. Differences in chloride load and strong ion difference across solutions appear to be clinically important. Phases of fluid therapy in acutely ill patients are recognized, including acute resuscitation, maintaining homeostasis, and recovery phases. Quantitative toxicity(fluid overload) is associated with adverse outcomes and can be mitigated when fluid therapy basedon functional hemodynamic parameters that predict volume responsiveness and minimization of non-essential fluid. Qualitative toxicity(fluid type), in particular for iatrogenic acute kidney injury and metabolic acidosis, remain a concern for synthetic colloids and isotonic saline, respectively. Physiologically balanced crystalloids may be the ‘‘default'' fluid for acutely ill patients and the role for colloids, in particular hydroxyethyl starch, is increasingly unclear. We contend the prescription of fluid therapy is analogous to the prescription of any drug used in critically ill patients.

基于朴实OT模型的形式意义不对称研究概观

形式-意义不对称研究是伴随OT出现而兴起的课题和学术难题。本文主要介绍基于朴实OT模型的形式-意义不对称解决方案及其相关评论,并作适当简评。

Occupational Therapy in Cancer Survivorship—A Toolkit for Stimulating Rapid-Research on the Neglected Domain of “Participation” during COVID-19

COVID-19 has disrupted people’s occupational daily activities with detrimental impact on their daily living performances and quality of life. Occupational therapy contributes toward restoring health by remediating limitation in participation in meaningful occupation with lifestyle redesign interventions. However, the research gap on the area of “participation-limitation” for the field of Occupational Therapy in cancer survivorship during the COVID-19 is largely untapped and unknown. This commentary-review paper discussed the PEO-OT (person-environment-occupation) grid as a conceptual toolkit for stimulating research in the domain of occupational participation—an essential aspect in the field of occupational therapy, for cancer survivors. It applies the expertise finding from a large Delphi study on research priority in the fields and integrating these into evidenced methodology, to provide a structure to guide the novice researchers towards rapid reviews, by selecting evidence-based methods to ensure contextually-relevant enquiry to identify the “occupational-participation issues”—i.e., an emerging social determinant of health, affecting the daily self-management of cancer survivors with or without comorbidities.

手术联合光动力治疗头部脓肿性穿掘性毛囊周围炎的临床疗效观察

目的:观察手术联合光动力治疗头部脓肿性穿掘性毛囊周围炎的临床疗效。方法:回顾性分析2021年1月-2022年6月笔者医院给予手术联合光动力治疗的24例头部脓肿性穿掘性毛囊周围炎患者临床资料。观察所有患者的临床治疗效果、不良反应和复发情况。结果:纳入治疗的患者痊愈13例(54.17%),显效6例(25.00%),有效3例(12.50%),无效2例(8.33%),总有效率91.67%。伤口均甲级愈合,未出现术后感染、皮瓣坏死、溃疡等并发症。随访0.5~2年,复发4例,复发率16.67%。大部分患者术后瘢痕不明显,患者满意度高。结论:手术联合光动力治疗头部脓肿性穿掘性毛囊周围炎疗效良好,可提高患者生活质量,且安全性好,复发率低。

基于OTS系统的酸碱中和系统的建模与仿真

为不断完善火电厂工业废水酸碱中和系统的控制策略,同时为电厂操作人员的岗前培训提供一个操作平台,基于Intouch组态软件以及OTS系统开发了一套酸碱中和系统的仿真软件。该软件是对酸碱中和系统的建模与仿真,最大程度地实现了火电厂酸碱中和系统的各项基本控制功能,动态模拟和参数显示;为电厂酸碱中和系统的优化控制算法提供了实验平台,同时为火电厂技术人员提供良好的培训工具。

IT与OT的融合会出现什么?

在过去的50年中,IT和OT(运营技术)一直保持彼此独立,属于不同的世界。过去十年中发生了很多的并购,但几个大型供应商在各自的IT和OT领域里,位置一直非常巩固。现在这两个世界即将走到一起,融合会发生什么?能否会导致制造业更好的结果?

Combined modality therapy for stage Ⅰ_B cervical cancer

Objective:To evaluate the current approaches for multimodality therapy for stage ⅠB cervical cancer.Methods:The relevant literature has served as a source for identified high or intermediate risks and management of stage ⅠB cervical cancer.Result:The high risks include pelvic lymph node metastasis(PLNM),positive resection margin(PRM),and the involvement of parametrium(IPM).The intermediate risks include deep stromal invasion(DSI),bulky tumor size(BTS),lymphovascular space invasion(LVSI).Adeno-carcinomatous histotype is the new risk feature relevant to poor prognoses.Both radical hysterectomy plus bilateral pelvic lymph node dissection(PLND) and radical radiotherapy have proven to be equally effective.Surgery is more performed for stage ⅠB1 disease;radiotherapy or chemoradiotherapy is preferable for stage ⅠB2 disease.For patients with one high risk or two of intermediate risks,radical hysterectomy plus PLND followed by concurrent chemoradiotherapy can improve overall survival(OS) and disease-free survival(DFS).Conclusion:The management should be individualized for stage ⅠB cervical cancer.The optimized multidisciplinary therapy can benefit patients with the best cure and minimum morbidity and complications.