The year 2014 was a tipping point for the Barack Obama Administration--that was the year when it strove to forge a legacy of the Obarna era but came up against challenges arising from major changes that were taking pl...The year 2014 was a tipping point for the Barack Obama Administration--that was the year when it strove to forge a legacy of the Obarna era but came up against challenges arising from major changes that were taking place internationally and domestically. The Administration was then focused on maintaining a fragile balance between creating this legacy and responding to these challenges. Obama stuck to his fundamental principles when dealing with overseas affairs, but he also came up with new responses. The dynamic balance struck between these two formed the basis of the global strategy of the late-term Obama Administration. The Administration's focus at this time highlights the dilemma it faced in forging a legacy. Further, the foreign policy of Obama and Trump are actually not so different; they both supported some degree of isolationism with a focus on domestic issues.展开更多
Obama's election draws the world's attention because of his skin color,so is his inaugural address.The paper analyzes his inaugural address according to the parameter of the three metafunctions from the perspe...Obama's election draws the world's attention because of his skin color,so is his inaugural address.The paper analyzes his inaugural address according to the parameter of the three metafunctions from the perspective of systemic functional grammar:ideational,interpersonal and textual.Accordingly,transitivity system,Mood and modality,and thematic progression in the address are respectively examined.展开更多
Based on three aesthetic criteria of logos, pathos and ethos in classic rhetoric theory, this article analyzes the modes of persuasion applied in Barack Obama's first inaugural speech. It has been found out that t...Based on three aesthetic criteria of logos, pathos and ethos in classic rhetoric theory, this article analyzes the modes of persuasion applied in Barack Obama's first inaugural speech. It has been found out that the perfect combination of these three appeals endows the speech with the rhetoric charm, passion and art of language which efficiently helps Obama to guarantee the political success in election.展开更多
The exact solution of fractional diffusion model with a location-independent source term used in the study of the concentration of fission product in spherical uranium dioxide (U02) particle is built. The adsorption...The exact solution of fractional diffusion model with a location-independent source term used in the study of the concentration of fission product in spherical uranium dioxide (U02) particle is built. The adsorption effect of the fission product on the surface of the U02 particle and the delayed decay effect are also considered. The solution is given in terms of Mittag-Leffler function with finite Hankel integral transformation and Laplace transformation. At last, the reduced forms of the solution under some special physical conditions, which is used in nuclear engineering, are obtained and corresponding remarks are given to provide significant exact results to the concentration analysis of nuclear fission products in nuclear reactor.展开更多
Alzheimer's disease(AD)redefined:For the past century,AD has been defined as a disease of progressive cognitive decline paired with a burden of amyloid-β(Aβ)plaques and pathologic tau tangles in the hippocampu...Alzheimer's disease(AD)redefined:For the past century,AD has been defined as a disease of progressive cognitive decline paired with a burden of amyloid-β(Aβ)plaques and pathologic tau tangles in the hippocampus and forebrain.However,a recent Framework paper jointly sponsored by the National Institute on Aging and the Alzheimer's Association(Jack et al.,2018)proposes new classification guidelines for AD,which,if adopted,will have profoundconsequences for the future management of AD.展开更多
This paper aims to explain the restraint exerted by the deep structure of culture,such as history,religion,social convention and family,in understanding and appreciating foreign verbal humor,especially foreign statesm...This paper aims to explain the restraint exerted by the deep structure of culture,such as history,religion,social convention and family,in understanding and appreciating foreign verbal humor,especially foreign statesman's verbal humor;whereby the significance of the deep structure of culture is revealed.In this paper,Herbert Paul Grice's Conversational Implicature Theory,i.e.the violation of cooperative principle,is taken as the theoretic base;the deep structure of culture is the analytical background and some of Obama's remarks and speeches given informal occasions are taken as analyzed examples,from which the essential role of the deep structure of culture is emphasized and focused in cross-cultural communication.展开更多
We have previously found that long-term effects of exposure to radiofrequency electromagnetic fields in 5xFAD mice with severe late-stage Alzheimer’s disease reduced both amyloid-βdeposition and glial activation,inc...We have previously found that long-term effects of exposure to radiofrequency electromagnetic fields in 5xFAD mice with severe late-stage Alzheimer’s disease reduced both amyloid-βdeposition and glial activation,including microglia.To examine whether this therapeutic effect is due to the regulation of activated microglia,we analyzed mic roglial gene expression profiles and the existence of microglia in the brain in this study.5xFAD mice at the age of 1.5 months were assigned to sham-and radiofrequency electromagnetic fields-exposed groups and then animals were exposed to 1950 MHz radiofrequency electromagnetic fields at a specific absorption rate of 5 W/kg for 2 hours/day and 5 days/week for 6 months.We conducted behavioral tests including the object recognition and Y-maze tests and molecular and histopathological analysis of amyloid precursor protein/a myloid-beta metabolism in brain tissue.We confirmed that radiofrequency electromagnetic field exposure for 6 months ameliorated cognitive impairment and amyloid-βdeposition.The expression levels of Iba1(pan-microglial marker)and colony-stimulating factor 1 receptor(CSF1R;regulates microglial prolife ration)in the hippocampus in 5xFAD mice treated with radiofrequency electromagnetic fields were significantly reduced compared with those of the sham-exposed group.Subsequently,we analyzed the expression levels of genes related to mic rogliosis and microglial function in the radiofrequency electromagnetic fields-exposed group compared to those of a CSF1R inhibitor(PLX3397)-treated group.Both radiofrequency electromagnetic fields and PLX3397 suppressed the levels of genes related to microgliosis(Csf1r,CD68,and Ccl6)and pro-inflammatory cytokine interleukin-1β.N otably,the expression levels of genes related to mic roglial function,including Trem2,Fcgr1α,Ctss,and Spi1,were decreased after long-term radiofrequency electromagnetic field exposure,which was also observed in response to microglial suppression by PLX3397.These results showed that radiofrequency electromagnetic fields ameliorated amyloid-βpathology and cognitive impairment by suppressing amyloid-βdeposition-induced microgliosis and their key regulator,CSF1R.展开更多
Translation of address terms is a very significant part in the translation of literary works.Yet the agreement on how to do their translation has not been settled.This thesis will make a detailed comparison of the tra...Translation of address terms is a very significant part in the translation of literary works.Yet the agreement on how to do their translation has not been settled.This thesis will make a detailed comparison of the translation of address terms in the extracted examples from Hongloumeng from the perspective of relevance theory(RT).It is believed that address terms are closely context-and culture-bounded,so there is no settled results for the translation of a particular address term.But the there are general rules to direct their translation from the perspective of RT by focusing on the context and the writer’s intention.展开更多
F_(10.7)指数是太阳活动的重要指标,准确预测F_(10.7)指数有助于预防和缓解太阳活动对无线电通信、导航和卫星通信等领域的影响.基于F_(10.7)射电流量的特性,在双向长短时记忆网络(Bidirectional Long Short-Term Memory Network,BiLSTM...F_(10.7)指数是太阳活动的重要指标,准确预测F_(10.7)指数有助于预防和缓解太阳活动对无线电通信、导航和卫星通信等领域的影响.基于F_(10.7)射电流量的特性,在双向长短时记忆网络(Bidirectional Long Short-Term Memory Network,BiLSTM)基础上融入注意力机制(Attention),提出了一种基于BiLSTM-Attention的F_(10.7)预报模型.在加拿大DRAO数据集上其平均绝对误差(MAE)为5.38,平均绝对百分比误差(MAPE)控制在5%以内,相关系数(R)高达0.987,与其他RNN模型相比拥有优越的预测性能.针对中国廊坊L&S望远镜观测的F_(10.7)数据集,提出了一种转换平均校准(Conversion Average Calibration,CAC)方法进行数据预处理,处理后的数据与DRAO数据集具有较高的相关性.基于该数据集对比分析了RNN系列模型的预报效果,实验结果表明,BiLSTM-Attention和BiLSTM两种模型在预测F_(10.7)指数方面具有较好的优势,表现出较好的预测性能和稳定性.展开更多
According to Reiss’s Text Type theory,a key part of the functionalist approach in translation studies,the source text can be assigned to a text type and to a genre.In making this assignment,the translator can decide ...According to Reiss’s Text Type theory,a key part of the functionalist approach in translation studies,the source text can be assigned to a text type and to a genre.In making this assignment,the translator can decide on the hierarchy of postulates which has to be observed during target-text production(Mona,2005).This essay intends to conduct a linguistic and stylistic analysis of the Chinese translation of Obama’s speech to explore the general approach of the translator(if there is one),by comparing the respective results of the two analyses from the perspective of Katharina Reiss’s Text Type theory.In doing so,critical judgments will accordingly be made as to whether such an approach is justifiable or not.展开更多
Background and Aims: On November 24, 2009, Huu S. TIEU and Golden Sunrise Pharmaceutical, Inc. (Golden Sunrise) applied for the Technology and Innovation to be reviewed and evaluated by the U.S. Food and Drug Administ...Background and Aims: On November 24, 2009, Huu S. TIEU and Golden Sunrise Pharmaceutical, Inc. (Golden Sunrise) applied for the Technology and Innovation to be reviewed and evaluated by the U.S. Food and Drug Administration (FDA). In the review and evaluation, it was requested by Golden Sunrise designated the new indications for this application under Serious or Life-threatening conditions or diseases. Discussions followed with the FDA, Huu S. TIEU, and Golden Sunrise for FDA approval on new products and new indications on existing new Medical Technology and Innovation. It was agreed in Year-2015 that the FDA would take the request for new indications to the United States Congress to establish into FDA regulation and law. At that time the following was the FDA Guidance—“Emergency Use of a Test Article” is exempt from prior Institutional Review Board or Advisory Committee evaluation and approval, provided that such emergency use is reported to the Institutional Review Board within five working days after use. Expedited Institutional Review Board or Advisory Committee approval is not permitted in emergency use. There has been no funding to the authors for the writing or publication of this article. Methods: It was requested by Huu S. TIEU and Golden Sunrise in documents given to the FDA to have Serious or Life-threatening conditions or diseases indication be recognized by law. On August 08, 2015, the FDA responding to this request took the documentation produced by Golden Sunrise to the United States Congress on behalf of Golden Sunrise and Huu S. TIEU. This article encompasses the FDA regulatory method as well as the discussion and results of the establishment of the FDA and the 21<sup>st</sup> Century Cures Act. Results: On December 13, 2016, H.R.34—114<sup>th</sup> United States Congress (2015-2016) 21<sup>st</sup> Century CURES Act was signed into law by President Barack H. Obama which included the Serious or Life-threatening indication to be written into the CURES Act. In summary, the 21<sup>st</sup> Century Cures Act is a landmark piece of legislation that enjoyed broad bipartisan support in United States Congress. The main goals of the Act are impactful and should transform future cancer, neurologic, and precision medicine or drug research as well as aid individuals with mental health is intended to facilitate the prompt approval of new agents and devices, clinicians should be aware of the types of data behind an approval and take this into consideration when developing illnesses and opioid dependence. However, some of the wording within the CURES Act regarding the drug and device approval process may bring pause to health care providers including pharmacists. Although this wording and implementing care plans and counseling patients. The 21<sup>st</sup> Century Cures Act was incorporated into laws and regulations by the FDA under § 3072 of the Act grants the Commissioner of Food and Drugs the authority to appoint and set the annual rate of pay for outstanding and qualified candidates to scientific, technical, or professional positions that support the development, review, and regulation of medical products.展开更多
This paper attempts to conduct a comparative study on Obama’s two speeches—his second inaugural address and his commencement speech in The Ohio State University in 2013 based on Halliday’s theory of Interpersonal F...This paper attempts to conduct a comparative study on Obama’s two speeches—his second inaugural address and his commencement speech in The Ohio State University in 2013 based on Halliday’s theory of Interpersonal Function.The author finds that mood,modality and personal pronouns are the major language means used to realize the interpersonal function;in his two speeches,Obama makes different choices of those resources,and different choices indicate different attitudes and intentions.展开更多
The paper applies a one-to-one correspondence which exists between individual Schr?dinger perturbation terms and the diagrams obtained on a circular scale of time to whole sets of the Schr?dinger terms belonging to a ...The paper applies a one-to-one correspondence which exists between individual Schr?dinger perturbation terms and the diagrams obtained on a circular scale of time to whole sets of the Schr?dinger terms belonging to a definite perturbation order. In effect the diagram properties allowed us to derive the recurrence formulae giving the number of higher perturbative terms from the number of lower order terms. This recurrence formalism is based on a complementary property that any perturbation order N can be composed of two positive integer components Na , Nb combined into N in all possible ways. Another result concerns the degeneracy of the perturbative terms. This degeneracy is shown to be only twofold and the terms having it are easily detectable on the basis of a circular scale. An analysis of this type demonstrates that the degeneracy of the perturbative terms does not exist for very low perturbative orders. But when the perturbative order exceeds five, the number of degenerate terms predominates heavily over that of nondegenerate terms.展开更多
文摘The year 2014 was a tipping point for the Barack Obama Administration--that was the year when it strove to forge a legacy of the Obarna era but came up against challenges arising from major changes that were taking place internationally and domestically. The Administration was then focused on maintaining a fragile balance between creating this legacy and responding to these challenges. Obama stuck to his fundamental principles when dealing with overseas affairs, but he also came up with new responses. The dynamic balance struck between these two formed the basis of the global strategy of the late-term Obama Administration. The Administration's focus at this time highlights the dilemma it faced in forging a legacy. Further, the foreign policy of Obama and Trump are actually not so different; they both supported some degree of isolationism with a focus on domestic issues.
文摘Obama's election draws the world's attention because of his skin color,so is his inaugural address.The paper analyzes his inaugural address according to the parameter of the three metafunctions from the perspective of systemic functional grammar:ideational,interpersonal and textual.Accordingly,transitivity system,Mood and modality,and thematic progression in the address are respectively examined.
文摘Based on three aesthetic criteria of logos, pathos and ethos in classic rhetoric theory, this article analyzes the modes of persuasion applied in Barack Obama's first inaugural speech. It has been found out that the perfect combination of these three appeals endows the speech with the rhetoric charm, passion and art of language which efficiently helps Obama to guarantee the political success in election.
基金Supported by the National S&T Major Project under Grant No.ZX06901
文摘The exact solution of fractional diffusion model with a location-independent source term used in the study of the concentration of fission product in spherical uranium dioxide (U02) particle is built. The adsorption effect of the fission product on the surface of the U02 particle and the delayed decay effect are also considered. The solution is given in terms of Mittag-Leffler function with finite Hankel integral transformation and Laplace transformation. At last, the reduced forms of the solution under some special physical conditions, which is used in nuclear engineering, are obtained and corresponding remarks are given to provide significant exact results to the concentration analysis of nuclear fission products in nuclear reactor.
文摘Alzheimer's disease(AD)redefined:For the past century,AD has been defined as a disease of progressive cognitive decline paired with a burden of amyloid-β(Aβ)plaques and pathologic tau tangles in the hippocampus and forebrain.However,a recent Framework paper jointly sponsored by the National Institute on Aging and the Alzheimer's Association(Jack et al.,2018)proposes new classification guidelines for AD,which,if adopted,will have profoundconsequences for the future management of AD.
文摘This paper aims to explain the restraint exerted by the deep structure of culture,such as history,religion,social convention and family,in understanding and appreciating foreign verbal humor,especially foreign statesman's verbal humor;whereby the significance of the deep structure of culture is revealed.In this paper,Herbert Paul Grice's Conversational Implicature Theory,i.e.the violation of cooperative principle,is taken as the theoretic base;the deep structure of culture is the analytical background and some of Obama's remarks and speeches given informal occasions are taken as analyzed examples,from which the essential role of the deep structure of culture is emphasized and focused in cross-cultural communication.
基金Institute of Information&Communications Technology Planning&Evaluation(IITP)grant funded by Korea government(MSIT),Nos.2017-0-00961 and 2019-0-00102(to HDC)。
文摘We have previously found that long-term effects of exposure to radiofrequency electromagnetic fields in 5xFAD mice with severe late-stage Alzheimer’s disease reduced both amyloid-βdeposition and glial activation,including microglia.To examine whether this therapeutic effect is due to the regulation of activated microglia,we analyzed mic roglial gene expression profiles and the existence of microglia in the brain in this study.5xFAD mice at the age of 1.5 months were assigned to sham-and radiofrequency electromagnetic fields-exposed groups and then animals were exposed to 1950 MHz radiofrequency electromagnetic fields at a specific absorption rate of 5 W/kg for 2 hours/day and 5 days/week for 6 months.We conducted behavioral tests including the object recognition and Y-maze tests and molecular and histopathological analysis of amyloid precursor protein/a myloid-beta metabolism in brain tissue.We confirmed that radiofrequency electromagnetic field exposure for 6 months ameliorated cognitive impairment and amyloid-βdeposition.The expression levels of Iba1(pan-microglial marker)and colony-stimulating factor 1 receptor(CSF1R;regulates microglial prolife ration)in the hippocampus in 5xFAD mice treated with radiofrequency electromagnetic fields were significantly reduced compared with those of the sham-exposed group.Subsequently,we analyzed the expression levels of genes related to mic rogliosis and microglial function in the radiofrequency electromagnetic fields-exposed group compared to those of a CSF1R inhibitor(PLX3397)-treated group.Both radiofrequency electromagnetic fields and PLX3397 suppressed the levels of genes related to microgliosis(Csf1r,CD68,and Ccl6)and pro-inflammatory cytokine interleukin-1β.N otably,the expression levels of genes related to mic roglial function,including Trem2,Fcgr1α,Ctss,and Spi1,were decreased after long-term radiofrequency electromagnetic field exposure,which was also observed in response to microglial suppression by PLX3397.These results showed that radiofrequency electromagnetic fields ameliorated amyloid-βpathology and cognitive impairment by suppressing amyloid-βdeposition-induced microgliosis and their key regulator,CSF1R.
文摘Translation of address terms is a very significant part in the translation of literary works.Yet the agreement on how to do their translation has not been settled.This thesis will make a detailed comparison of the translation of address terms in the extracted examples from Hongloumeng from the perspective of relevance theory(RT).It is believed that address terms are closely context-and culture-bounded,so there is no settled results for the translation of a particular address term.But the there are general rules to direct their translation from the perspective of RT by focusing on the context and the writer’s intention.
文摘F_(10.7)指数是太阳活动的重要指标,准确预测F_(10.7)指数有助于预防和缓解太阳活动对无线电通信、导航和卫星通信等领域的影响.基于F_(10.7)射电流量的特性,在双向长短时记忆网络(Bidirectional Long Short-Term Memory Network,BiLSTM)基础上融入注意力机制(Attention),提出了一种基于BiLSTM-Attention的F_(10.7)预报模型.在加拿大DRAO数据集上其平均绝对误差(MAE)为5.38,平均绝对百分比误差(MAPE)控制在5%以内,相关系数(R)高达0.987,与其他RNN模型相比拥有优越的预测性能.针对中国廊坊L&S望远镜观测的F_(10.7)数据集,提出了一种转换平均校准(Conversion Average Calibration,CAC)方法进行数据预处理,处理后的数据与DRAO数据集具有较高的相关性.基于该数据集对比分析了RNN系列模型的预报效果,实验结果表明,BiLSTM-Attention和BiLSTM两种模型在预测F_(10.7)指数方面具有较好的优势,表现出较好的预测性能和稳定性.
文摘According to Reiss’s Text Type theory,a key part of the functionalist approach in translation studies,the source text can be assigned to a text type and to a genre.In making this assignment,the translator can decide on the hierarchy of postulates which has to be observed during target-text production(Mona,2005).This essay intends to conduct a linguistic and stylistic analysis of the Chinese translation of Obama’s speech to explore the general approach of the translator(if there is one),by comparing the respective results of the two analyses from the perspective of Katharina Reiss’s Text Type theory.In doing so,critical judgments will accordingly be made as to whether such an approach is justifiable or not.
文摘Background and Aims: On November 24, 2009, Huu S. TIEU and Golden Sunrise Pharmaceutical, Inc. (Golden Sunrise) applied for the Technology and Innovation to be reviewed and evaluated by the U.S. Food and Drug Administration (FDA). In the review and evaluation, it was requested by Golden Sunrise designated the new indications for this application under Serious or Life-threatening conditions or diseases. Discussions followed with the FDA, Huu S. TIEU, and Golden Sunrise for FDA approval on new products and new indications on existing new Medical Technology and Innovation. It was agreed in Year-2015 that the FDA would take the request for new indications to the United States Congress to establish into FDA regulation and law. At that time the following was the FDA Guidance—“Emergency Use of a Test Article” is exempt from prior Institutional Review Board or Advisory Committee evaluation and approval, provided that such emergency use is reported to the Institutional Review Board within five working days after use. Expedited Institutional Review Board or Advisory Committee approval is not permitted in emergency use. There has been no funding to the authors for the writing or publication of this article. Methods: It was requested by Huu S. TIEU and Golden Sunrise in documents given to the FDA to have Serious or Life-threatening conditions or diseases indication be recognized by law. On August 08, 2015, the FDA responding to this request took the documentation produced by Golden Sunrise to the United States Congress on behalf of Golden Sunrise and Huu S. TIEU. This article encompasses the FDA regulatory method as well as the discussion and results of the establishment of the FDA and the 21<sup>st</sup> Century Cures Act. Results: On December 13, 2016, H.R.34—114<sup>th</sup> United States Congress (2015-2016) 21<sup>st</sup> Century CURES Act was signed into law by President Barack H. Obama which included the Serious or Life-threatening indication to be written into the CURES Act. In summary, the 21<sup>st</sup> Century Cures Act is a landmark piece of legislation that enjoyed broad bipartisan support in United States Congress. The main goals of the Act are impactful and should transform future cancer, neurologic, and precision medicine or drug research as well as aid individuals with mental health is intended to facilitate the prompt approval of new agents and devices, clinicians should be aware of the types of data behind an approval and take this into consideration when developing illnesses and opioid dependence. However, some of the wording within the CURES Act regarding the drug and device approval process may bring pause to health care providers including pharmacists. Although this wording and implementing care plans and counseling patients. The 21<sup>st</sup> Century Cures Act was incorporated into laws and regulations by the FDA under § 3072 of the Act grants the Commissioner of Food and Drugs the authority to appoint and set the annual rate of pay for outstanding and qualified candidates to scientific, technical, or professional positions that support the development, review, and regulation of medical products.
文摘This paper attempts to conduct a comparative study on Obama’s two speeches—his second inaugural address and his commencement speech in The Ohio State University in 2013 based on Halliday’s theory of Interpersonal Function.The author finds that mood,modality and personal pronouns are the major language means used to realize the interpersonal function;in his two speeches,Obama makes different choices of those resources,and different choices indicate different attitudes and intentions.
文摘The paper applies a one-to-one correspondence which exists between individual Schr?dinger perturbation terms and the diagrams obtained on a circular scale of time to whole sets of the Schr?dinger terms belonging to a definite perturbation order. In effect the diagram properties allowed us to derive the recurrence formulae giving the number of higher perturbative terms from the number of lower order terms. This recurrence formalism is based on a complementary property that any perturbation order N can be composed of two positive integer components Na , Nb combined into N in all possible ways. Another result concerns the degeneracy of the perturbative terms. This degeneracy is shown to be only twofold and the terms having it are easily detectable on the basis of a circular scale. An analysis of this type demonstrates that the degeneracy of the perturbative terms does not exist for very low perturbative orders. But when the perturbative order exceeds five, the number of degenerate terms predominates heavily over that of nondegenerate terms.