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Preoperative Serum Albumin Levels and Postoperative Acute Kidney Injury in Off-Pump Coronary Artery Bypass Surgery: A Single-Center Study in Bangladesh
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作者 Ahmad Pear Salahuddin Md. Abir Tazim Chowdhury +6 位作者 Munama Magdum Dewan Iftakher Reza Chowdhury Nittya Nanda Pal Md. Nahedul Morshed Md. Zafar-Al-Nimari Latifa Nasrin Farooque Ahmed 《World Journal of Cardiovascular Surgery》 2024年第8期131-144,共14页
Background: Serum albumin, a vital plasma protein, helps maintain intravascular colloidal osmotic pressure, cardiac output, and renal function. Low preoperative serum albumin is linked to poor outcomes, including acut... Background: Serum albumin, a vital plasma protein, helps maintain intravascular colloidal osmotic pressure, cardiac output, and renal function. Low preoperative serum albumin is linked to poor outcomes, including acute kidney injury (AKI), after off-pump coronary artery bypass (OPCAB) surgery. This study aimed to assess the relationship between preoperative serum albumin levels and early postoperative renal injury. Methods: This prospective comparative cross-sectional study was conducted from August 2019 to February 2021 at the National Heart Foundation Hospital & Research Institute, Bangladesh. It included 160 adult patients with normal preoperative renal function undergoing OPCAB. Patients were divided into two groups: Group A (serum albumin ≥ 4.0 gm/dl) and Group B (serum albumin Results: Preoperative serum albumin was significantly different between groups (Group A: 4.21 ± 0.05 gm/dl, Group B: 3.69 ± 0.04 gm/dl, p = 0.028). Group B had a higher incidence of hypertension (71.25% vs. 51.25%, p st and 3rd postoperative days were higher in Group B (p th day. Postoperative AKI occurred in 18.75% of Group A and 36.25% of Group B. Multivariate regression indicated that low preoperative serum albumin is an independent risk factor for postoperative AKI (p = 0.012, OR = 1.815, CI: 0.675 - 1.162). Conclusion: Preoperative serum albumin level is a valuable predictor of postoperative renal function. Ensuring high normal serum albumin levels before surgery can help minimize the risk of postoperative AKI. 展开更多
关键词 Serum Albumin Acute Kidney Injury (AKI) off-pump coronary artery bypass Surgery BANGLADESH
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Off-Pump Coronary Artery Bypass Grafting in Patients with Left Ventricular Dysfunction: Short-Term Results from a Single Center in Bangladesh
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作者 Muhit Abdullah Md. Abir Tazim Chowdhury +9 位作者 Satyajit Sharma Rehana Akther Munama Magdum Munjerin Refat Synthee Md. Zafar-Al-Nimari Saikat Das Gupta Saleh Ahmed Samir Kumar Biswas M. Quamrul Islam Talukder Farooque Ahmed 《World Journal of Cardiovascular Surgery》 2024年第9期145-156,共12页
Background: Off-pump coronary artery bypass grafting (OPCAB) is considered a safer alternative to on-pump surgery, especially in patients with left ventricular dysfunction (LVD). Objectives: This study assessed short-... Background: Off-pump coronary artery bypass grafting (OPCAB) is considered a safer alternative to on-pump surgery, especially in patients with left ventricular dysfunction (LVD). Objectives: This study assessed short-term outcomes and functional improvements in LVD patients post-OPCAB. Methods: The study included 200 coronary artery disease patients who underwent isolated off-pump coronary artery bypass grafting (OPCAB) at the National Heart Foundation Hospital and Research Institute between January 2019 and June 2020. Patients were categorized into Group 1, with a left ventricular ejection fraction (LVEF) of 30% - 39%, and Group 2, with an LVEF of 40% or higher. Echocardiographic assessments of left ventricular dimensions and ejection fraction were performed preoperatively, at discharge, and one month postoperatively. Results: In Group 1, preoperative left ventricular internal dimensions during diastole (LVIDd) and systole (LVIDs) were 53.48 ± 4.40 mm and 44.23 ± 3.93 mm, respectively, with a left ventricular ejection fraction (LVEF) of 35.28% ± 2.26%. At discharge, these values improved to 51.58 ± 4.04 mm (LVIDd), 41.23 ± 5.30 mm (LVIDs), and 39.25% ± 3.75% (LVEF). One month postoperatively, further improvements were observed: 46.29 ± 3.76 mm (LVIDd), 37.45 ± 3.68 mm (LVIDs), and 43.22% ± 4.67% (LVEF). Group 2 showed similar positive outcomes, with preoperative values of 47.09 ± 5.06 mm (LVIDd), 35.11 ± 5.25 mm (LVIDs), and 50.13% ± 7.25% (LVEF), improving to 42.37 ± 4.18 mm (LVIDd), 31.05 ± 4.19 mm (LVIDs), and 55.33% ± 7.05% (LVEF) at one month postoperatively. Both groups demonstrated significant improvements in left ventricular function and NYHA class, with most patients moving from class III/IV to I/II. Complications were minimal, and no mortality was observed. Conclusion: OPCAB is safe and effective for patients with LVEF 30% - 39% and LVEF ≥ 40%, providing significant short-term functional improvements without increased risk. 展开更多
关键词 off-pump coronary artery bypass Grafting Left Ventricular Dysfunction (LVD) Short-Term Outcomes
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Off-pump coronary artery bypass grafting using a bilateral internal mammary artery Y graft 被引量:10
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作者 Cheng-Xiong Gu Jun-Feng Yang +2 位作者 Hong-Chao Zhang Hua Wei Ling-Ke Li 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2012年第3期247-251,共5页
Objective To evaluate the outcome of off-pump coronary artery bypass grafting (OPCABG) using a bilateral internal mammary artery (BIMA) Y configuration graft to achieve total arterial myocardial revascularization.... Objective To evaluate the outcome of off-pump coronary artery bypass grafting (OPCABG) using a bilateral internal mammary artery (BIMA) Y configuration graft to achieve total arterial myocardial revascularization. Methods From October 2002 to December 2008, 208 patients (196 males and 12 females) underwent OPCABG using a BIMA Y configuration graft. The average age of the patients was 56.5 ± 11.3 years, with an age range of 33-78 years. A total of 167 (80.2%) cases had triple-vessel disease. Left main stem disease was found in 33 (15.9%) cases, and double-vessel disease was found in 8 (3.9%) cases. The semi-skeletonization technique was used to harvest the two internal mammary arteries (IMAs), and then the free right internal mammary artery was connected end-to-side to the left internal mammary artery (LIMA) in situ to complete the Y configuration graft. Off-pump and sequential anastomosis methods were used to perform coronary artery bypass surgery in all patients. Graft patency was assessed intm-operatively with the HT311 transit time flowmeter. Results A total of 728 distal anastomoses were performed in 208 patients, with the average being 3.5± 1.3 per person. No one died or experienced recurrent angina within 30 days after the operation. Conclusions OPCABG using the BIMA Y graft was safe and effective to achieve total arterial revascularization. This method avoids surgical operation on the ascending aorta and other incisions. 展开更多
关键词 Bilateral internal mammary arteries coronary artery bypass grafting Internal mammary artery off-pump
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Off-pump coronary artery bypass grafting versus on-pump coronary artery bypass grafting: which is better in patients with chronic obstructive pulmonary disease? 被引量:9
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作者 朱亚彬 许建屏 +3 位作者 刘志勇 杨丹宁 李旭东 李鸿雁 《Journal of Zhejiang University Science》 CSCD 2004年第8期1005-1008,共4页
To evaluate the clinic outcome of off-pump coronary bypass grafting (OPCABG) of patients with coronary heart disease and chronic obstructive pulmonary disease, we collected and analyzed 1998-2002 data on 28 patients w... To evaluate the clinic outcome of off-pump coronary bypass grafting (OPCABG) of patients with coronary heart disease and chronic obstructive pulmonary disease, we collected and analyzed 1998-2002 data on 28 patients with these two diseases who had received off-pump coronary bypass operation in our hospital, and compared with data on those who also had the same two diseases but received on-pump coronary artery bypass at same time. There were no operation-related death;one died of respiratory failure 14 days after operation while staying in hospital; there were more respiratory complications in the conventional coronary artery bypass grafting group (CCABG) than in the OPCABG group; and the PaO2/FiO2 in the CCABG group was higher than that in the OPCABG group during operation because of CPB, but lower than that in the OPCABG group 6-12 hours after operation. OPCABG seemed more suitable than CCABG for coronary artery disease patients with chronic obstructive pulmonary disease due to less damage to their oxygen-exchange capability and the fewer respiratory complications. 展开更多
关键词 Chronic obstructive pulmonary disease coronary artery heart disease off-pump bypass On-pump bypass Respiratory function
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Clopidogrel improves aspirin response after off-pump coronary artery bypass surgery 被引量:5
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作者 Xuezhong Wang Xiaoxuan Gong +5 位作者 Tiantian Zhu Qiu Zhang Yangyang Zhang Xiaowei Wang Zhijian Yang Chunjian Lia 《The Journal of Biomedical Research》 CAS 2014年第2期108-113,共6页
We sought to assess the incidence of aspirin resistance after off-pump coronary artery bypass (OPCAB) surgery, and investigate whether clopidogrel can improve aspirin response and be safely applied early after OPCAB... We sought to assess the incidence of aspirin resistance after off-pump coronary artery bypass (OPCAB) surgery, and investigate whether clopidogrel can improve aspirin response and be safely applied early after OPCAB surgery. Sixty patients who underwent standard OPCAB surgery were randomized into two groups. One group (30 patients) received mono-antiplatelet treatment (MAPT) with aspirin 100 mg daily and the other group received dual anfiplatelet treatment (DAPT) with aspirin 100 mg daily plus clopidogrel 75 mg daily. Platelet aggregations in response to arachi- donic acid (PLAA) and adenosine diphosphate (ADP) (PLADP) were measured preoperatively and on days 1 to 6, 8 and 10 after the antiplatelet agents were administered. A PLAA level above 20% was defined as aspirin resistance. Postoperative bleeding and other perioperative variables were also recorded. There were no significant differences between the two groups in baseline characteristics, average number of distal anastomosis, operation time, postoperative bleeding, ventilation time and postoperative hospital stay. However, the incidence of aspirin resistance was significantly lower in the DAPT group than that in the MAPT group on the first and second day after antiplatelet agents were given (62.1% vs, 32.1%, 34.5% vs. 10.7%, respectively, both P 〈 0.05). There was no significant difference in postoperative complication between the two groups. DAPT with aspirin and clopidogrel can be safely applied to OPCAB patients early after the procedure. Moreover, clopidogrel reduces the incidence of OPCAB-related aspirin resistance. 展开更多
关键词 ASPIRIN CLOPIDOGREL aspirin resistance off-pump coronary artery bypass (OPCAB)
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Off-pump coronary artery bypass grafting versus optimal medical therapy alone:effectiveness of incomplete revascularization in high risk patients 被引量:4
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作者 Filippo Prestipino Cristiano Spadaccio +5 位作者 Antonio Nenna Fraser WH Sutherland Gwyn W Beattie Mario Lusini Francesco Nappi Massimo Chello 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2016年第1期23-30,共8页
BackgroundGeriatric patients with multivessel coronary artery disease (CAD) are a challenging group to treat; these cases elicit dis-cussion within heart teams regarding the actual benefit of undertaking major surge... BackgroundGeriatric patients with multivessel coronary artery disease (CAD) are a challenging group to treat; these cases elicit dis-cussion within heart teams regarding the actual benefit of undertaking major surgery on these patients and often lead to abandon the surgical option. Percutaneous procedures represent an important option, but coronary anatomy may be unfavorable. Off-pump coronary artery bypass (OPCAB) provides good quality graft on left anterior descending (LAD) without exposing the patient to cardiopulmonary bypass, and might be the ideal choice in patients with multiple comorbidities, not eligible to percutaneous or on-pump procedures. The objective of this study was to compare survival during a mid-term follow-up in high-risk patients with no percutaneous alternative, either treated with OPCAB or discharged in medical therapy.MethodsWe retrospectively evaluated from June 2008 to June 2013, 83 high-risk patients with multivessel CAD were included: 42 were treated with incomplete off-pump revascularization using left internal mammary artery (LIMA) on LAD; 41 were discharged in optimal medical therapy (OMT), having refused surgery. Follow-up ended in March 2015, with a telephonic interview. Primary endpoint was survival from all-cause mortality; secondary endpoints were survival from cardiac-related mortality and freedom from non-fatal major adverse cardiac events (MACEs).ResultsDuring follow up, 11 deaths in OPCAB group and 27 deaths in OMT group occurred. Death was due to cardiac factors in 6 and 15 patients, respectively. MACEs were observed in 6 patients in OPCAB group and in 4 patients in OMT group. With regards to survival from all-cause mortality, patients who underwent OPCAB survived more than those dis-charged in OMT (Log Rank &lt; 0.001), and OMT group carries a propensity score-adjusted hazard ratio of 3.862 (P &lt; 0.001). With regards to survival from cardiac-related events, patients who underwent OPCAB survived more than those discharged in OMT (Log Rank = 0.002), and OMT group carries a propensity score-adjusted hazard ratio of 3.663 (P = 0.010). There is no statistically significant difference concerning freedom from MACEs (Log Rank = 0.273).ConclusionsFor high-risk patients with multivessel CAD, not eligible to on-pump complete revascularization surgery or percutaneous procedures, incomplete revascularization with OPCAB LIMA-on-LAD offers benefits in survival when compared to OMT alone. 展开更多
关键词 coronary artery disease Myocardial revascularization off-pump coronary artery bypass Survival analysis
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Off-pump coronary artery bypass grafting: Misperceptions and misconceptions 被引量:4
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作者 Shahzad G Raja Umberto Benedetto 《World Journal of Methodology》 2014年第1期6-10,共5页
Coronary artery bypass grafting(CABG) continues to be one of the most commonly performed cardiac surgical procedures worldwide. Conventional CABG performed on cardiopulmonary bypass termed on-pump CABG is regarded as ... Coronary artery bypass grafting(CABG) continues to be one of the most commonly performed cardiac surgical procedures worldwide. Conventional CABG performed on cardiopulmonary bypass termed on-pump CABG is regarded as the gold standard. However, on-pump CABG results in several physiologic derangements including but not limited to thrombocytopenia, activation of complement factors, immune suppression, and inflammatory responses leading to organ dysfunction.Furthermore, manipulating an atherosclerotic ascending aorta during cannulation and cross-clamping can predispose to embolization and stroke risk. Recognition of these detrimental effects of on-pump CABG resulted in resurgence of off-pump CABG nearly two decades ago.Off-pump CABG since its resurgence has been a subject of intensive scrutiny and speculation. Despite numerous retrospective nonrandomized studies, prospective randomized trials, and meta-analyses validating the safety and efficacy of off-pump CABG, opponents of the technique have persistently demanded abandonment of off-pump CABG. Several misconceptions and misperceptions are used as an excuse for such demands. This review article examines published scientific evidence to evaluate these misperceptions and misconceptions about off-pump CABG. 展开更多
关键词 coronary artery bypass GRAFTING Cardiopulmonary bypass off-pump coronary artery bypass GRAFTING Surgical myocardial revascularization coronary artery surgery
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Off-pump versus on-pump coronary artery bypass surgery for the treatment of left main with triple coronary artery disease 被引量:3
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作者 Zhibing Qiu Xin Chen Ming Xu Kaihu Shi Yinshuo Jiang Liqiong Xiao 《Journal of Nanjing Medical University》 2008年第3期159-163,共5页
Objective:To obtain early results of off-pump coronarE~ artery bypass grafting(OPCAB) in patients with significant left main coronary artery(LMCA) and triple vessels stenosis by comparing with those of a similar ... Objective:To obtain early results of off-pump coronarE~ artery bypass grafting(OPCAB) in patients with significant left main coronary artery(LMCA) and triple vessels stenosis by comparing with those of a similar group undergoing conventional coronary artery bypass surgery(CCAB). Methods:Data for patients with significant LMCA and triple vessels stenosis who underwent CCAB or OPCAB were collected retrospectively between January 1999 and May 2006. Non-randomized, retrospective data analysis included demo- graphic and preoperative risk factors, operative details, clinical outcome and early follow-up. Results: The number of distal anastomo- sis and grafts varied from 3 to 6. The average number per patient was similar in the two groups (OPCAB group:3.76 ± 0.98, CCAB group:3.81 ± 1.02). Thirty-day mortality occurred to one patient in the OPCAB group whereas two early deaths were observed in the CCAB group but did not reach statistical significance (P 〉 0.05). The frequency of atrial fibrillation (AF), IABP usage, mediastinitis, re-operation for bleeding (or tamponade) were similar in the two groups (P 〉 0.05). Postoperative inotropic requirements, peak CKMB, ventilation time, blood loss, FFP, RBC transfusion need and the length of ICU-stay were all significantly lower in the OPCAB group compared with CCAB group(P 〈 0.05).Conclusion: Significant LMCA and triple-vessel stenosis can safely and effectively undergo myocardial revascularization using OPCAB surgery. LMCA should no longer be seen as a contraindication to perform OPCAB grafting. 展开更多
关键词 left main coronary artery triple-vessel stenosis off-pump coronary artery bypass grafting
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Incidence of Atrial Fibrillation after Off-pump versus On-pump Coronary Artery Bypass Grafting:A Meta-analysis of Randomized Clinical Trials and Propensity Score Matching Trials 被引量:1
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作者 吴创炎 王思桦 +1 位作者 尚玉强 夏家红 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2017年第6期956-964,共9页
The association between atrial fibrillation(AF) after coronary artery bypass grafting(CABG) and the surgical techniques selected has been extensively reported. However, no consistent results were obtained. In the ... The association between atrial fibrillation(AF) after coronary artery bypass grafting(CABG) and the surgical techniques selected has been extensively reported. However, no consistent results were obtained. In the present study, a meta-analysis was conducted by searching the electronic databases Pub Med, Embase, Web of Science, and Cochrane to identify the association of post-CABG AF with on-pump(conventional CABG, c CABG) or off-pump CABG(OPCABG). Outcomes from randomized clinical trials(RCTs) and propensity score matching(PSM) trials were pooled by using the fixed-effect or the random-effect modeling method, and verified by the quality-effect modeling method. There were 35 studies with 36 independent reports that met the inclusion criteria and were eventually included in our meta-analysis. The total odds ratio(OR) of the incidence of post-CABG AF between OPCABG and c CABG was 0.80(95% CI 0.71–0.91). The 25 randomized clinical trials(RCTs) had an OR of 0.69(95% CI 0.56–0.86), while the OR of the 11 PSM trials was 0.88(95% CI 0.77–1.00). Twenty-six studies involving the patients at a mean age no more than 65 years showed an OR of 0.76(95% CI 0.64–0.90), whereas 10 studies with patients greater than 65 years old showed an OR of 0.90(95% CI 0.78–1.05). The results of this meta-analysis suggest that OPCAB surgery may reduce the incidence of post-CABG AF when compared to c CABG and that younger patients may benefit more from OPCAB and have a lower incidence of post-CABG AF. 展开更多
关键词 off-pump coronary artery bypass coronary artery bypass surgery atrial fibrillation
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Role of Intra-Aortic Balloon Pump in Off-Pump Coronary Artery Bypass —A Vettath Modification 被引量:1
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作者 Murali P. Vettath Kannan A. Vellachamy +2 位作者 Nitin Gangadharan Sanooj Ottuparakuzhiyil Jayaprakash Moothencherie 《World Journal of Cardiovascular Diseases》 2016年第6期188-195,共8页
Objective: Hemodynamic deterioration during positioning of the heart has been the most critical complication of off-pump coronary artery bypass surgery. Pre-operative use of intra-aortic balloon pump has been shown to... Objective: Hemodynamic deterioration during positioning of the heart has been the most critical complication of off-pump coronary artery bypass surgery. Pre-operative use of intra-aortic balloon pump has been shown to prevent this complication in high risk patients. The role of balloon pump in high risk patients has been questioned by our group. We modified the role of balloon pump in our patients, thus avoiding the conversion to cardiopulmonary bypass. Methods: 4063 off-pump coronary bypass surgeries were performed by a single surgeon in our center, over thirteen years. 130 intra-aortic balloons used between July 2002 and December 2015 were removed from the the-ater, once the distal anastomosis was performed. We studied this group of patients for—time and need for insertion, duration of balloon used, local insertion problems and survival. Results: Initially, we inserted intra-aortic balloons in high risk patients. We observed that, patients with low ejection fraction and patients with critical left main coronary artery disease were not the ones who actually needed balloon pump support. It was the patients who had ongoing ischemia, with preserved left ventricular function, and ST depression intra-operatively, who needed balloon pump support to perform complete anatomical revascularization. Conclusions: Intra-aortic balloon pump has helped us to position the heart without hemodynamic instability, thereby avoiding conversion to cardio-pulmonary bypass. This enabled us to perform off-pump surgery in virtually all areas of the heart, thus maintaining perfect hemodynamics. 展开更多
关键词 off-pump coronary artery bypass (OPCAB) Surgery Intra-Aortic Balloon Pump (IABP)
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Tei index evaluates left ventricular function changes after on-pump and off-pump coronary artery bypass surgery
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作者 王茵 赵宝珍 +3 位作者 王尔松 徐志云 梅举 熊文峰 《Journal of Medical Colleges of PLA(China)》 CAS 2006年第2期125-128,共4页
Objective: To compare function recovery of left ventricle after off-pump and on-pump coronary artery bypass (OPCAB and ONCAB) using Tel index. Methods: Twenty-four patients with coronary artery disease were enroll... Objective: To compare function recovery of left ventricle after off-pump and on-pump coronary artery bypass (OPCAB and ONCAB) using Tel index. Methods: Twenty-four patients with coronary artery disease were enrolled, twelve of which received OPCAB and the others underwent ONCAB. Left ventricular ejection fraction (LVEF), E/A ratio at mitral orifice and Tel index were measured using transthoracic echocardiography before surgery and 3-7 days, 1 month, 3 months and 6 months after surgery. Results:Tel index of both groups decreased 3-7 days after surgery, with OPCAB group's lower than ONCAB group's. The difference between pre-and post-OPCAB was significant (P〈0.01), but not for ONCAB group (P〈0.05). Tel index of ONCAB decreased more significant than that of OPCAB 1 month after surgery, there was statistical difference between 3-7 days and 1 month after surgery in ONCAB (P〈0.01). Afterwards, Tel index of the 2 groups decreased steadily with no significant difference between them at other time points. LVEF and E/A ratio decreased at first, then increased gradually, with no statistical differences between the 2 groups at all time points. Conclusion: The recovery of left ventricular function after OPCAB is earlier than ONCAB. Tel index is more sensitive than LVEF and E/A ratio in detecting cardiac function recoveries and can be considered as an accurate and simple method to evaluate left ventricular systolic and diastolic function. 展开更多
关键词 Tei index coronary artery bypass off-pump left ventricular function
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Nutritional supplement drink reduces inflammation and postoperative depression in patients after off-pump coronary artery bypass surgery
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作者 Satoshi Matsushita Akie Shimada +4 位作者 Taira Yamamoto Kazuo Minematsu Hirotaka Inaba Kenji Kuwaki Atsushi Amano 《World Journal of Cardiology》 2021年第8期348-360,共13页
BACKGROUND Coronary artery bypass grafting is a surgical treatment for ischemic heart disease.Although development in surgical technique and improvement of perioperative management reduced the postoperative complicati... BACKGROUND Coronary artery bypass grafting is a surgical treatment for ischemic heart disease.Although development in surgical technique and improvement of perioperative management reduced the postoperative complications,some patients still delayed in progress of postoperative rehabilitation.In this study,we aimed to investigate the effect of daily intake of an herbal medicine-containing drink for rehabilitation after surgery in patients with ischemic heart disease.AIM To investigate the effect of taking an herbal medicine-containing,commercially available drink for postoperative rehabilitation in those patients.METHODS Patients who underwent isolated off-pump coronary artery bypass(OPCAB)surgery were divided into two groups depend on the timing of the admission to the hospital:the Yunker(YKR)group,that consumed one bottle of a caffeine-free nutritional supplement drink on a daily basis and the control group(CTL)that underwent regular rehabilitation.RESULTS A total of 229 patients(CTL=130,YKR=99)were enrolled.No significant differences were observed in the baseline characteristics between the two groups.The YKR group had a significantly increased number of daily steps postoperatively(P<0.05)and had significantly lower postoperative serum tumor necrosis factor-alpha levels(P<0.01),while no significant differences were observed in the levels of other inflammatory or stress-related cytokines(interleukin-6,adiponectin,superoxide dismutase,and urine 8-hydroxy-2′-deoxyguanosine)between the two groups.Also,the YKR group showed a significant improvement in the Hospital Anxiety and Depression Score(P<0.05).Moreover,there were no differences in postoperative complications and the duration of postoperative hospital stay between the two groups.CONCLUSION Our results demonstrated that the daily intake of an herbal medicine-containing drink after OPCAB surgery may have beneficial effects on cardiac rehabilitation by reducing inflammation markers and depression. 展开更多
关键词 Herbal medicine INFLAMMATION Cardiac rehabilitation Moderate-to-vigorous intensity physical activity off-pump coronary artery bypass
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Comparative study of graft flow between on-pump and off-pump coronary bypass surgery for patients with multivessel coronary artery disease
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作者 Xin Chen Ming Xu Zhibing Qiu Yinshuo Jiang Liming Wang Liqiong Xiao 《Journal of Nanjing Medical University》 2006年第6期351-354,共4页
Objective: To Comparatively study grafts flow between on-pump and off-pump coronary bypass surgery for patients with triple coronary artery disease. Methods : The grafts flow was studied in 100 patients of OPCAB and... Objective: To Comparatively study grafts flow between on-pump and off-pump coronary bypass surgery for patients with triple coronary artery disease. Methods : The grafts flow was studied in 100 patients of OPCAB and compared with 100 cases of CCABG by means of Medi-Stim Butterfly Flowmeter measurement intraoperatively. Results: The mean number of the distal anastomosis was 3.78+ 1.11 in CCABG group, and 3.83 + 0.93 in OPCAB group. The index of completeness of revascularization in CCABG group was 1.01 + 0.08, and 1.10+ 0.09 in OPCAB group. The flow of grafts was satisfied in all patients. The PI values were all under 5. There was no significant difference in the mean graft flow and PI value between two groups. Conclusion: OPCAB can provide the same grafts flow and similar completeness of revascularization when compared with CCABG which indicates the similar anastomosis quality of grafts in OPCAB and CCABG groups. 展开更多
关键词 off-pump coronary artery bypass grafting flow of grafts REVASCULARIZATION
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Association of Atrial Fibrillation and Amino-terminal Pro-brain Natriuretic Peptide Concentrations in Patients After Off-Pump Coronary Artery Bypass Grafting
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作者 李君权 张庆华 +1 位作者 田伟忱 刘宏宇 《South China Journal of Cardiology》 CAS 2008年第2期61-65,共5页
Objectives To investigate the possible role of amino-terminal pro-brain natriuretic peptide (NT-proBNP) in the occurrence of atrial fibrillation (AF) after coronary artery bypass grafting (CABG). Methods This st... Objectives To investigate the possible role of amino-terminal pro-brain natriuretic peptide (NT-proBNP) in the occurrence of atrial fibrillation (AF) after coronary artery bypass grafting (CABG). Methods This study group included 70 consecutive patients scheduled for elective off-pump CABG. The patients with ejection fraction (EF) less than 0. 30, history of AF, use of class Ⅰ or Ⅲ antiarrhythmic drug, implanted pacemaker, postoperative myocardial infarction or chest reopening for pericardial tamponade were excluded. Preoperative and postoperative serum NT-proBNP levels were measured by radioimmunoassay technique. Results Postoperative AF occurred in 15 patients (21.4%); these patients had significantly higher median NT-proBNP levels when compared with those without AF after the operation ( P 〈 0. 01 ). Using multivariate logistic regression analyses, an increase in NT-proBNP level after CABG was found to be independently associated with AF ( OR = 3.78, 95% IC = 1.81 - 4. 89, P 〈 0. 01 ). Increased age, diabetes mellitus, preoperative use of β-blocker, proximal right coronary artery involvement, and longer operation time were al- so associated with AF. Conclusions These results indicated that AF was associated with higher NT-proBNP concentrations after off pump CABG; the increase in NT-proBNP after CABG may play an important role in the occurrence of AF after the operation. The further studies are needed to define the reason that lead to higher NT-proBNP concentrations among the patients who present AF after off pump CABG. 展开更多
关键词 off-pump coronary artery bypass grafting atrial fibrillation amino-terminal pro-brain natriuretic peptide
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The perioperative effects of metabolic syndrome on the off-pump coronary artery bypass
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作者 毛斌 《外科研究与新技术》 2011年第3期179-180,共2页
Objective Metabolic syndrome (MS),a disorder involving multiple metabolic abnormalities such obesity,hypertension,diabetes or abnormal glucose tolerance anddyslipidemia,has been observed in many patients receiving cor... Objective Metabolic syndrome (MS),a disorder involving multiple metabolic abnormalities such obesity,hypertension,diabetes or abnormal glucose tolerance anddyslipidemia,has been observed in many patients receiving coronary artery bypass procedures. In this study we try to examine the perioperative effects of metabolic syndrome on the off-pump coronary artery 展开更多
关键词 OPCABG IABP The perioperative effects of metabolic syndrome on the off-pump coronary artery bypass ECMO
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Stroke following off-pump coronary artery bypass in patients with prior stroke
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作者 曹莉 《外科研究与新技术》 2011年第3期180-180,共1页
Objective To analyze the risk factors and clinical features of stroke following off-pump coronary artery bypass grafting in patients with prior stroke. Methods From January 2006 to July 2009,the clinical information o... Objective To analyze the risk factors and clinical features of stroke following off-pump coronary artery bypass grafting in patients with prior stroke. Methods From January 2006 to July 2009,the clinical information of 437 patients undergoing OPCABG in Anzhen Hospital 展开更多
关键词 OPCABG Stroke following off-pump coronary artery bypass in patients with prior stroke THAN
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The prediction of early mortality in off-pump coronary artery bypass surgery:SinoSCORE versus EuroSCORE
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作者 中国心血管外科注册登记研究协作组 《外科研究与新技术》 2011年第3期182-182,共1页
Objective To compare the validation of the Sino System for Coronary Operative Risk Evaluation (SinoSCORE) with the European system for cardiac operative risk evaluation (EuroSCORE) in patients undergoing off-pump coro... Objective To compare the validation of the Sino System for Coronary Operative Risk Evaluation (SinoSCORE) with the European system for cardiac operative risk evaluation (EuroSCORE) in patients undergoing off-pump coronary artery bypass (OPCAB) surgery in China. Methods Data of patients who underwent OPCAB between 2004 and 2005 in 展开更多
关键词 OPCAB The prediction of early mortality in off-pump coronary artery bypass surgery
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Comparison of long-term graft patency of on-pump versus off-pump coronary artery bypass grafting
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作者 吴强 《外科研究与新技术》 2011年第3期172-172,共1页
Objective Off-pump coronary artery bypass grafting (OPCAB) is used more widely in recent years in China. However,there is an argument on benefits and risks of off-pump surgery. Many studies shown that OPCAB had more b... Objective Off-pump coronary artery bypass grafting (OPCAB) is used more widely in recent years in China. However,there is an argument on benefits and risks of off-pump surgery. Many studies shown that OPCAB had more benefits in short-term outcomes than conventional coronary artery bypass grafting (CCABG) . 展开更多
关键词 OPCAB Comparison of long-term graft patency of on-pump versus off-pump coronary artery bypass grafting
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Coronary artery bypass grafting with concomitant resection for carcinoma of lung 被引量:4
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作者 Yangyang Zhang,Yanhu Wu ,Biao Yuan,Xiang Liu,Sheng Zhao,Zhi Li,Yu Xia Department of Cardiothoracic Surgery,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,Jiangsu Province,China 《The Journal of Biomedical Research》 CAS 2010年第1期77-80,共4页
A 69-year-old woman with angina had a lesion in the left lower lobe on chest film. Angiography revealed coronary artery disease in three vessels. Combined off pump coronary artery bypass grafting (CABG) and left low... A 69-year-old woman with angina had a lesion in the left lower lobe on chest film. Angiography revealed coronary artery disease in three vessels. Combined off pump coronary artery bypass grafting (CABG) and left lower lobectomy were performed through median sternotomy. This approach avoids complications due to staged operations and cardiopulmonary bypass (CPB). This report shows that simultaneous off pump CABG and pulmonary operations can be performed safely in patients with coronary artery disease (CAD) associated with lung cancer. 展开更多
关键词 lung cancer coronary artery disease luo- resection off-pump coronary artery bypass grafting
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Preoperative P-wave duration as a predictor of atrial fibrillation after coronary artery bypass grafting: A prospective cohort study with meta-analysis 被引量:1
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作者 Fangqin Wu Ying Wu +2 位作者 Wenyan Tao Haibo Zhao Dongyan Shen 《International Journal of Nursing Sciences》 2018年第2期151-156,共6页
Objectives:Reported prediction rules for postoperative atrial fibrillation(AF)have suffered from inconsistent results and controversy surrounding the predictive value of a preoperative P-wave duration(PreOPWD).This st... Objectives:Reported prediction rules for postoperative atrial fibrillation(AF)have suffered from inconsistent results and controversy surrounding the predictive value of a preoperative P-wave duration(PreOPWD).This study examined PreOPWD as a predictor for AF after coronary artery bypass grafting(CABG).Methods:Two-hundred-and-ninety-nine patients with sinus rhythm before off-pump CABG were recruited into the study.Patients'demographic and clinical data were evaluated prospectively.Patients were continuously monitored for the first seven postoperative days.Multiple logistic regressionwas used to determine significant predictors of AF.Findings were then combined with similar studies and a metaanalysis was performed.Results:Postoperative AF was observed in 33.1%of 299 patients.Patients with AF were older,had a prolonged PreOPWD,higher incidences of hypertension,aortic regurgitation,and mitral regurgitation.A cut-off point of PreOPWD105ms achieved a specificity of 74%,and a sensitivity of 65%for predictive of AF.Multivariate analysis showed that PreOPWD105ms(odds ratio[OR]4.63,95%confidence intervals[CI]2.66 to 8.03,P<0.001),age60 years(OR 2.72,95%CI 1.51 to 4.90,P<0.01)and hypertension(OR 2.10,95%CI 1.08 to 4.07,P<0.05)independently predicted postoperative AF.A meta-analysis of this data combined with those of ten other studies showed that PreOPWD was greater in patients with POAF,with a weighted mean difference of 3.95 ms(95%CI 1.97 to 5.92,P<0.001).Conclusion:This study confirmed,among other predictive characteristics,that PreOPWD is a powerful independent predictor of POAF. 展开更多
关键词 Atrial fibrillation coronary artery bypass off-pump Cohort studies META-ANALYSIS
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