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Effectiveness and postoperative rehabilitation of one-stage combined anterior-posterior surgery for severe thoracolumbar fractures with spinal cord injury 被引量:1
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作者 Bo Zhang Jin-Chao Wang +2 位作者 Yu-Zhen Jiang Qing-Peng Song Yan An 《World Journal of Clinical Cases》 SCIE 2022年第18期6001-6008,共8页
BACKGROUND Thoracolumbar fractures are generally combined with spinal cord injury to varying degrees,which may cause deterioration of the patients’condition and increase the difficulty of clinical treatment.At presen... BACKGROUND Thoracolumbar fractures are generally combined with spinal cord injury to varying degrees,which may cause deterioration of the patients’condition and increase the difficulty of clinical treatment.At present,anterior or combined anterior-posterior surgery is preferred for severe thoracolumbar fractures.AIM To investigate the effectiveness and postoperative rehabilitation of one-stage combined anterior-posterior surgery for severe thoracolumbar fractures with spinal cord injury.METHODS One-hundred-and-twenty patients who received surgery for severe thoracolumbar fractures with spinal cord injury at our hospital from February 2018 to February 2020 were randomly enrolled.They were randomly divided into group 1(one-stage combined anterior-posterior surgery,n=60)and group 2(onestage anterior-approach surgery,n=60).Treatment efficacy was compared between the two groups.RESULTS Blood loss was greater and the operation time was longer in group 1 than in group 2,and the differences were statistically significant(P<0.05).Incision length,intraoperative X-rays,and length of hospital stay were not significantly different between the two groups(P>0.05).Preoperative function of the affected vertebrae was not significantly different between the two groups(P>0.05).In each group,the patients showed significant improvement after surgery.The anterior vertebral height ratio and the posterior vertebral height ratio in group 1 after surgery were significantly higher than those in group 2.The Cobb angle after surgery was significantly lower in group 1 than in group 2(P<0.05).The canal-occupying ratio of the affected vertebrae was not significantly different between the two groups(P>0.05).Before surgery,there was no significant difference in the quality of life scores between the two groups(P>0.05).The above indicators were significantly improved after surgery compared with before surgery in each group.In addition,these indicators were markedly better in group 1 than in group 2 after surgery(P<0.05 for each).CONCLUSION One-stage combined anterior-posterior surgery effectively improves the function of the affected vertebrae and the life quality of patients with severe thoracolumbar fractures and spinal cord injury.This surgical approach is worthy of popularization in clinical use. 展开更多
关键词 thoracolumbar fracture spinal cord injury Combined anterior-posterior surgery Postoperative rehabilitation Quality of life
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Efficacy of Spinal Pia Mater Incision and Laminoplasty Combined with Internal Fixation for Old Spinal Cord Injury 被引量:4
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作者 Gen-long Jiao Zhi-zhong Li +2 位作者 Ming Tan Yong-qin Pan Zhi-gang Zhou 《Chinese Medical Sciences Journal》 CAS CSCD 2012年第3期134-140,共7页
Objective To evaluate the clinical efficacy of incising spinal pia mater to relieve pressure and unilateral open-door laminoplasty with internal screw fixation for treatment of the dated spinal cord injury. Methods Fr... Objective To evaluate the clinical efficacy of incising spinal pia mater to relieve pressure and unilateral open-door laminoplasty with internal screw fixation for treatment of the dated spinal cord injury. Methods From March, 2009 to July, 2010, 16 cases with chronic cervical cord injury underwent spinal dura mater incision and unilateral open-door laminoplasty with internal screw fixation. Nerve functions of preand postoperation were evaluated by Frankel classification and the Japanese Orthopaedic Association (JOA) scale. The improvement rate of JOA score at the indicated time was recorded. Results Postoperative Frankel classification rating of 16 patients improved obviously. JOA scores at the 1st month, 3rd month, 6th month, and 12th month after surgery were 7.9±2.3, 8.5±1.6, 8.9±2.1, and 12.4±2.5, respectively, and significantly increased compared with that prior to surgery (5.5±0.6). At the end of follow-up period, JOA score was significantly higher than that of pre-treatment (P<0.05). The recovery was relatively rapid during the first 3 months following the surgery, then entered a platform period. Conclusion It is effective for patients with dated spinal cord injury to undergo spinal decompression and laminoplasty. 展开更多
关键词 spinal pia mater DECOMPRESSION LAMINOPLASTY old spinal cord injury
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Radiographic measurement of morphological abnormalities in thoracolumbar burst fractures: relationship with spinal cord lesion
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作者 戴力扬 《Journal of Medical Colleges of PLA(China)》 CAS 2000年第3期214-216,共3页
Objective:To investigate the relationship between morphological abnormalities and spinal cord deficit in thoracolumbar burst fractures. Methods: Seventy-eight patients with thoracolumbar burst fractures were retrospec... Objective:To investigate the relationship between morphological abnormalities and spinal cord deficit in thoracolumbar burst fractures. Methods: Seventy-eight patients with thoracolumbar burst fractures were retrospectively reviewed to calculate the stenotic ratio of spinal canal based on the midsagittal diameters and the hyphosis angle according to Cobb. The ASIA scoring of motor function of lower extremities was recorded . Results: The differences (P > 0.05) of the stenotic ratio of spinal canal and the kyphosis angle were not significant between patients without neurological deficit, with incomplete and complete lesions. No significant correlation(P > 0.05) between the stenotic ratio of spinal canal and the kyphosis angle, and ASIA scoring was noted. Conclusion:The severity of spinal cord injuries in thoracolumbar burst fractures is not predicted according to the percentage of canal stenosis or the degree of kyphesis induced by thoracolumbar burst fractures. 展开更多
关键词 spinal fractures thoracic VERTEBRAE LUMBAR VERTEBRAE spinal CANAL spinal cord injuries
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An expert consensus on the evaluation and treatment of acute thoracolumbar spine and spinal cord injury in China 被引量:6
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作者 Zhicheng Zhang Fang Li Tiansheng Sun 《Neural Regeneration Research》 SCIE CAS CSCD 2013年第33期3077-3086,共10页
This is an expert consensus on the evaluation and treatment of thoracolumbar spinal injury, estab- lished from February 2009 to July 2010. The expert consensus consists mainly of six parts with a total of 54 recommend... This is an expert consensus on the evaluation and treatment of thoracolumbar spinal injury, estab- lished from February 2009 to July 2010. The expert consensus consists mainly of six parts with a total of 54 recommendations including the overview (one item); pre-hospital care (one item); evaluation and diagnosis (13 items); treatment (23 items); prevention and treatment of major com- plications (12 items); and rehabilitation (four items). This is the first time that Chinese experts have published a consensus on spine and spinal cord injury. The expert consensus was established based on Delphi methods, literature analysis, and clinical experiences. Each recommendation is supported by and was interpreted using multi-level evidences. The level of agreement with the rec- ommendation among the panel members was assessed as either low, moderate, or strong. Each panel member was asked to indicate his or her level of agreement on a 5-point scale, with "1" cor- respondJng to neutrality and "5" representJng maxJmum agreement. Scores were aggregated across the panel members and an arithmetic mean was calculated. This mean score was then translated into low, moderate, or strong. After all of the votes were collected and calculated, the results showed no low-level recommendations, 10 moderate-level recommendations, and 44 strong-level recom- mendations. An expert consensus was reached and was recognized by Chinese spine surgeons. Wide-scale adoption of these recommendations is urgent in the management of acute thora- columbar spine and spinal cord injury in a broader attempt to create a standard evaluation and treatment strategy for acute thoracolumbar spine and spinal cord injury in China. 展开更多
关键词 neural regeneration spinal cord injury expert consensus thoracolumbar spine and spinal cord injury guidelines evidence-based medicine neurological function diagnosis treatment rehabilitation grant-supported paper NEUROREGENERATION
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Establishment and validation of standardized animal models of spinal cord injury by normal external force-caused fracture dislocation 被引量:6
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作者 Weibing Shuang Qiang Liu +1 位作者 Shoubin Jiao Yang Yang 《Neural Regeneration Research》 SCIE CAS CSCD 2011年第35期2732-2738,共7页
The duplication of animal models plays a key role in spinal cord injury research; however, there has been limited study into normal, external force-derived fracture dislocation. This study adopted experimental devices... The duplication of animal models plays a key role in spinal cord injury research; however, there has been limited study into normal, external force-derived fracture dislocation. This study adopted experimental devices, designed in-house, to construct standardized ventral and dorsal spinal cord injury animal models of 6 g and 17 g falling from a height of 2, 4, and 10 cm, and 15, 30 or 50 g transversal compression on the spinal cord. The results showed that gradual increases in the degree of histopathological injury led to decreased Tarlov and Basso, Beattie and Bresnahan scores for the behavioral test, and increased Ashworth scores for the hind limb. Furthermore, there was a gradual decline in the slope test in the rats with dorsal spinal cord injury that correlated to increases in the falling substance weight or falling height. Similar alterations were observed in the ventral spinal cord injured rats, proportional to the increase in compression weight. Our experimental findings indicate that the standardized experimental rat models of dorsal and ventral spinal cord injury are stable, reliable and reproducible. 展开更多
关键词 spinal cord injury spinal cord compression animal models external force fracture dislocation behavior HISTOPATHOLOGY
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Application of a paraplegic gait orthosis in thoracolumbar spinal cord injury 被引量:2
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作者 Lang Shuai Guo-hua Yu +4 位作者 Zhen Feng Wan-song Wang Wei-ming Sun Lu Zhou Yin Yan 《Neural Regeneration Research》 SCIE CAS CSCD 2016年第12期1997-2003,共7页
Paraplegic gait orthosis has been shown to help paraplegic patients stand and walk, although this method cannot be individualized for patients with different spinal cord injuries and functional recovery of the lower e... Paraplegic gait orthosis has been shown to help paraplegic patients stand and walk, although this method cannot be individualized for patients with different spinal cord injuries and functional recovery of the lower extremities. There is, however, a great need to develop individualized paraplegic orthosis to improve overall quality of life for paraplegic patients. In the present study, 36 spinal cord(below T4) injury patients were equally and randomly divided into control and observation groups. The control group received systematic rehabilitation training, including maintenance of joint range of motion, residual muscle strength training, standing training, balance training, and functional electrical stimulation. The observation group received an individualized paraplegic locomotion brace and functional training according to the various spinal cord injury levels and muscle strength based on comprehensive systematic rehabilitation training. After 3 months of rehabilitation training, the observation group achieved therapeutic locomotion in 8 cases, family-based locomotion in 7 cases, and community-based locomotion in 3 cases. However, locomotion was not achieved in any of the control group patients. These findings suggest that individualized paraplegic braces significantly improve activity of daily living and locomotion in patients with thoracolumbar spinal cord injury. 展开更多
关键词 nerve regeneration spinal cord injury paraplegia brace thoracolumbar spine locomotion ability activity of daily living reciprocating gait orthosis hip-knee ankle foot orthosis knee-ankle foot orthosis ankle foot orthosis neural regeneration
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Management of acute spinal cord injury:A summary of the evidence pertaining to the acute management,operative and non-operative management 被引量:5
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作者 Darren Sandean 《World Journal of Orthopedics》 2020年第12期573-583,共11页
Acute traumatic spinal cord injury is often a lifechanging and devastating event with considerable mortality and morbidity.Over half a million people suffer from traumatic spinal cord injury annually with the majority... Acute traumatic spinal cord injury is often a lifechanging and devastating event with considerable mortality and morbidity.Over half a million people suffer from traumatic spinal cord injury annually with the majority resulting from road traffic accidents or falls.The Individual,societal and economic costs are enormous.Initial recognition and treatment of acute traumatic spinal cord injury are crucial to limit secondary injury to the spinal cord and to provide patients with the best chance of some functional recovery.This article is an overview of the management of the acute traumatic spinal cord injury patient presenting to the emergency department.We review the initial assessment,criteria for imaging and clearing the spine,and evaluate the literature to determine the optimum timing of surgery and the role of non-surgical treatment in patients presenting with acute spinal cord injury. 展开更多
关键词 Traumatic spinal cord injury Acute management spinal fracture Vertebral fracture spinal cord transection Traumatic myelopathy
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Thoracolumbar spine fracture complicated by simple conus medullaris injury
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作者 余斌 《Journal of Medical Colleges of PLA(China)》 CAS 1997年第4期283-285,共3页
Between 1990 and 1996, 15 patients with thoracolumbar spine fracture complicated by simple conusmedullaris injury were admitted. All patients were Injured by falling from height (mean, o meters). Clinical symp-toms in... Between 1990 and 1996, 15 patients with thoracolumbar spine fracture complicated by simple conusmedullaris injury were admitted. All patients were Injured by falling from height (mean, o meters). Clinical symp-toms indicated hypoesthesia or anesthesia of S3-5 sensory region,dysporia and urinary dysfunction. but normal sensation and motion of the bilateral lower extremities. Waston-Jones classified the spinal cord and nerve root injury following thoracolumbar spine fracture into three types. According to our observations, it should be classfied into five types: 1) concussion of the conus medullaris; 2) simple incomplete injury of the conus medullaris; 3) simplecomplete injury of the conus medullaris; 4) spinal cord transection and partial nerve root injury; 5) spinal cordtransection and entire nerve root injury. 展开更多
关键词 thoracolumbar SPINE fracture spinal cord injury clinical diagnosis
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Thoracic Spinal Cord Stab Injury: A Case Report and Literature Review
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作者 Aurélien Ndoumbe Marc Leroy Guifo +1 位作者 Mathieu Motah Samuel Takongmo 《Open Journal of Modern Neurosurgery》 2015年第4期113-117,共5页
Thoracic spinal cord stab injuries are rare lesions. A 17-year-old boy was stabbed on his back by his classmate when he bent forward to pick up his cloth from the ground. On admission, he presented with: complete para... Thoracic spinal cord stab injuries are rare lesions. A 17-year-old boy was stabbed on his back by his classmate when he bent forward to pick up his cloth from the ground. On admission, he presented with: complete paraplegia with muscle strength of zero on all muscle groups, complete anesthesia from dermatome 10 and below, acute urinary retention, and a four-centimeter wound on the thoracolumbar region from which cerebrospinal fluid mixed with blood was oozing out. A high-dose methylprednisolone protocol was started (30 mg/kg in one hour and then 5.4 mg/kg over 23 hours) an indwelling urinary catheter placed and sterile dressing of the wound done. Antibiotics and analgesics were also administered. The computed tomography scanning revealed a spinal cord transection at T10-T11 level with incarceration of the broken knife blade. An emergency thoracic laminectomy was performed. Removal of the broken knife blade revealed complete spinal cord transection with a compressive hematoma within the spinal cord which was removed by smooth suction. The spinal dura was sutured and the wound closed in many layers. On day 14 after surgery, sensitivity was recovered with 3 on 5 muscle strength in both lower limbs except for both feet where motor function remained null. Urinary retention and fecal incontinence persisted. The patient was discharged from our service for a rehabilitation center. At 32-month follow-up, neurological examination was unchanged although patient noticed a slight improvement of sphincter disturbances. 展开更多
关键词 spinal cord injury THORACIC Spine STAB Wound KNIFE Seventeen-Year-old BOY
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Pressure ulcers and acute risk factors in individuals with traumatic spinal fractures with or without spinal cord injuries:A prospective analysis of the National Spinal Column/Cord Injury Registry of Iran(NSCIR-IR)data 被引量:1
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作者 Farzin Farahbakhsh Hossein Rezaei Aliabadi +5 位作者 Vali Baigi Zahra Ghodsi Mohammad Dashtkoohi Ahmad Pour-Rashid James SHarrop Vafa Rahimi-Movaghar 《Chinese Journal of Traumatology》 CAS CSCD 2023年第4期193-198,共6页
Purpose:To identify risk factors for developing pressure ulcers(PUs)in the acute care period of traumatic spinal fracture patients with or without spinal cord injuries(SCIs).Methods:Data were collected prospectively i... Purpose:To identify risk factors for developing pressure ulcers(PUs)in the acute care period of traumatic spinal fracture patients with or without spinal cord injuries(SCIs).Methods:Data were collected prospectively in participating the National Spinal column/Cord Injury Registry of Iran(NSCIR-IR)from individuals with traumatic spinal fractures with or without SCIs,in-clusive of the hospital stay from admission to discharge.Trained nursing staff examined the patients for the presence of PUs every 8 h during their hospital stay.The presence and grade of PUs were assessed according to the European Pressure Ulcer Advisory Panel classification.In addition to PU,following data were also extracted from the NSCIR-IR datasets during the period of 2015-2021:age,sex,Glasgow coma scale score at admission,having SCIs,marital status,surgery for a spinal fracture,American Spinal Injury Association impairment scale(AIS),urinary incontinence,level of education,admitted center,length of stay in the intensive care unit(ICU),hypertension,respiratory diseases,consumption of ciga-rettes,diabetes mellitus and length of stay in the hospital.Logistic regression models were used to es-timate the unadjusted and adjusted odds ratio(OR)with 95%confidence intervals(CI).Results:Altogether 2785 participants with traumatic spinal fractures were included.Among them,87(3.1%)developed PU during their hospital stay and 392(14.1%)had SCIs.In the SCI population,63(16.1%)developed PU during hospital stay.Univariate logistic regression for the whole sample showed that marital status,having SCIs,urinary incontinence,level of education,treating center,number of days in the ICU,age,and Glasgow coma scale score were significant predictors for PUs.However,further analysis by multiple logistic regression only revealed the significant risk factors to be the treating center,marital status,having SCIs,and the number of days in the ICU.For the subgroup of individuals with SCIs,marital status,AIS,urinary incontinence,level of education,the treating center,the number of days in the ICU and the number of days in the hospital were significant predictors for PUs by univariate analysis.After adjustment in the multivariate model,the treating center,marital status(singles vs.marrieds,OR=3.06,95%CI:1.55-6.03,p=0.001),and number of days in the ICU(OR=1.06,95%Cl:1.04-1.09,p<0.001)maintained significance.Conclusions:These data confirm that individuals with traumatic spinal fractures and SCIs,especially single young patients who suffer from urinary incontinence,grades A-D by AIS,prolonged ICU stay,and more extended hospitalization are at increased risk for PUs;as a result strategies to minimize PU development need further refinement. 展开更多
关键词 spinal fractures spinal cord injuries Pressureulcer NSCIR-IR
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Spinal cord injury in the setting of traumatic thoracolumbar fracture is not reliably associated with increased risk of associated intra-abdominal injury following blunt trauma:An analysis of a National Trauma Registry database 被引量:12
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作者 Veacheslav Zilbermints Yehuda Hershkovitz +6 位作者 Kobi Peleg Joseph J.Dubose Adi Givon David Aranovich Mickey Dudkiewicz Israeli Trauma Group Boris Kessel 《Chinese Journal of Traumatology》 CAS CSCD 2021年第3期132-135,共4页
Purpose:There is a common opinion that spinal fractures usually reflect the substantial impact of injuries and therefore may be used as a marker of significant associated injuries,specifically for intra-abdominal inju... Purpose:There is a common opinion that spinal fractures usually reflect the substantial impact of injuries and therefore may be used as a marker of significant associated injuries,specifically for intra-abdominal injury(IAI).The impact of concomitant spinal cord injury(SCI)with the risk of associated IAI has not been well clarified.The aim of this study was to evaluate the incidence and severity of IAIs in patients suffering from spinal fractures with or without SCI.Methods:A retrospective cohort study using the Israeli National Trauma Registry was conducted.Patients with thoracic,lumbar and thoracolumbar fractures resulting from blunt mechanisms of injury from January 1,1997 to December 31,2018 were examined,comparing the incidence,severity and mortality of IAIs in patients with or without SCI.The collected variables included age,gender,mechanism of injury,incidence and severity of the concomitant IAIs and pelvic fractures,abbreviated injury scale,injury severity score,and mortality.Statistical analysis was performed using GraphPad InStat?Version 3.10,with Chi-square test for independence and two sided Fisher’s exact probability test.Results:Review of the Israeli National Trauma Database revealed a total of 16,878 patients with spinal fractures.Combined thoracic and lumbar fractures were observed in 1272 patients(7.5%),isolated thoracic fractures in 4967 patients(29.4%)and isolated lumbar fractures in 10,639 patients(63.0%).The incidence of concomitant SCI was found in 4.95%(63/1272),7.65%(380/4967)and 2.50%(266/10639)of these patients,respectively.The overall mortality was 2.5%,proving higher among isolated thoracic fracture patient than among isolated lumbar fracture counterparts(11.3%vs.4.6%,p<0.001).Isolated thoracic fractures with SCI were significantly more likely to die than non-SCI counterparts(8.2%vs.3.1%,p<0.001).There were no differences in the incidence of IAIs between patients with or without SCI following thoracolumbar fractures overall or in isolated thoracic fractures;although isolated lumbar fractures patients with SCI were more likely to have renal(3.4%vs.1.6%,p=0.02)or bowel injuries(2.3%vs.1.0%,p=0.04)than the non-SCI counterparts.Conclusion:SCI in the setting of thoracolumbar fracture does not appear to be a marker for associated IAI.However,in a subset of isolated lumbar fractures,SCI patient is associated with increased risks for renal and bowel injury. 展开更多
关键词 spinal fractures Blunt trauma Abdominal injuries spinal cord injury
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脊柱骨折合并脊髓损伤患者血清IL-17、DKK-1水平及其预后价值
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作者 郝强 孙丹丹 《国际检验医学杂志》 CAS 2024年第22期2800-2804,共5页
目的观察脊柱骨折合并脊髓损伤患者血清白细胞介素-17(IL-17)、分泌型蛋白Dickkopf-l(DKK-1)水平的变化,并探讨二者对患者预后不良的预测价值。方法选取2018年10月至2022年8月在该院就诊的133例接受椎管减压术治疗的脊柱骨折合并脊髓损... 目的观察脊柱骨折合并脊髓损伤患者血清白细胞介素-17(IL-17)、分泌型蛋白Dickkopf-l(DKK-1)水平的变化,并探讨二者对患者预后不良的预测价值。方法选取2018年10月至2022年8月在该院就诊的133例接受椎管减压术治疗的脊柱骨折合并脊髓损伤患者作为研究组,根据美国脊柱损伤协会(ASIA)神经功能等级,将其分为预后良好组(80例)和预后不良组(53例)。另选取同期在本院接受椎管减压术治疗的128例单纯脊柱骨折患者作为对照组,收集脊柱骨折合并脊髓损伤患者的临床资料。采用酶联免疫吸附试验(ELISA)检测所有患者血清IL-17、DKK-1水平。多因素Logistic回归分析患者预后影响因素。受试者工作特征(ROC)曲线分析IL-17、DKK-1水平对患者预后不良的诊断价值。结果研究组血清IL-17[(23.18±4.85)pg/mL vs.(12.97±3.91)pg/mL]、DKK-1水平[(2.48±0.41)ng/mL vs.(1.37±0.26)ng/mL]均高于对照组,差异有统计学意义(P<0.001)。预后不良组患者血清IL-17[(26.61±4.85)pg/mL vs.(20.91±3.81)pg/mL]、DKK-1水平[(2.83±0.48)ng/mL vs.(2.25±0.39)ng/mL]均显著高于预后良好组,差异有统计学意义(P<0.001)。IL-17、DKK-1为影响患者预后的独立危险因素(P<0.05)。血清IL-17、DKK-1及二者联合诊断患者预后不良的曲线下面积(AUC)分别为0.822(95%CI:0.746~0.883)、0.796(95%CI:0.718~0.861)和0.910(95%CI:0.848~0.953),联合诊断效能高于单独检测效能(Z联合诊断-IL-17=2.034,P=0.042;Z联合诊断-DKK-1=2.422,P=0.015)。结论脊柱骨折合并脊髓损伤患者血清IL-17、DKK-1水平升高,且二者水平对患者预后有一定诊断价值。 展开更多
关键词 脊柱骨折合并脊髓损伤 白细胞介素-17 分泌型蛋白Dickkopf-l 预后
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机器人辅助手术治疗脊柱骨折伴脊髓神经损伤的研究进展 被引量:2
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作者 吴博宇 范志海 《机器人外科学杂志(中英文)》 2024年第2期194-198,共5页
脊柱骨折作为骨科常见创伤之一,多由直接或间接外力引起,主要累及脊柱和周围软组织。脊柱骨折后正常生理结构改变,常导致脊髓神经受损、受压,且由于椎管内含脆弱神经,解剖结构复杂,对于手术精准性要求较高。机器人手术系统拥有自由度较... 脊柱骨折作为骨科常见创伤之一,多由直接或间接外力引起,主要累及脊柱和周围软组织。脊柱骨折后正常生理结构改变,常导致脊髓神经受损、受压,且由于椎管内含脆弱神经,解剖结构复杂,对于手术精准性要求较高。机器人手术系统拥有自由度较高的机械臂,术者可利用计算机实时导航跟踪、动态监测进针的精度与安全性,并能提高穿刺及置钉成功率,避免二次骨质破坏,减轻术者工作负荷。同时,机器人辅助治疗和康复方式在临床治疗中的应用,可为患者提供持续性神经治疗和康复,增加患者肌肉活动性,改善神经损伤情况,有利于患者肢体功能康复。本研究主要分析机器人辅助手术在脊柱骨折伴脊髓神经损伤中的应用,旨在为脊柱骨折伴脊髓神经损伤治疗提供指导。 展开更多
关键词 脊柱骨折 脊髓损伤 机器人辅助手术
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低强度脉冲超声在骨骼肌肉及运动神经系统中的生物学效应研究进展
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作者 李满平 陈绍丰 +4 位作者 程亚军 白玉树 李明 魏显招 周潇逸 《海军军医大学学报》 CAS CSCD 北大核心 2024年第8期1030-1035,共6页
低强度脉冲超声(LIPUS)是一种成本低、非侵袭性且安全性高的治疗方式,主要应用于骨骼肌肉系统疾病的治疗,尤其是骨折与骨不连的治疗。本文综述了LIPUS在多种骨骼肌肉及运动神经系统疾病中的治疗作用,并分析其可能的内在机制和潜在靶点,... 低强度脉冲超声(LIPUS)是一种成本低、非侵袭性且安全性高的治疗方式,主要应用于骨骼肌肉系统疾病的治疗,尤其是骨折与骨不连的治疗。本文综述了LIPUS在多种骨骼肌肉及运动神经系统疾病中的治疗作用,并分析其可能的内在机制和潜在靶点,发现除了骨折与骨不连之外,LIPUS在治疗骨质疏松、肌肉损伤及运动神经系统疾病中同样具有临床应用前景。 展开更多
关键词 低强度脉冲超声 骨折 骨不连 骨质疏松 肌肉损伤 脊髓损伤 运动神经元病
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胸腰椎骨折合并脊髓损伤术后感染因素及风险预测模型构建
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作者 于超 刘建生 +4 位作者 张磊 孟小娜 魏巍 杨艳 姚立军 《临床和实验医学杂志》 2024年第10期1048-1052,共5页
目的分析影响胸腰椎骨折合并脊髓损伤术后感染的因素,据此构建风险预测模型。方法采用回顾性分析进行研究,研究对象选自2022年1月至2022年12月在唐山市第二医院行手术治疗的148例胸腰椎骨折合并脊髓损伤患者。将其按照术后住院期间是否... 目的分析影响胸腰椎骨折合并脊髓损伤术后感染的因素,据此构建风险预测模型。方法采用回顾性分析进行研究,研究对象选自2022年1月至2022年12月在唐山市第二医院行手术治疗的148例胸腰椎骨折合并脊髓损伤患者。将其按照术后住院期间是否感染分为感染组(n=67)和非感染组(n=81)。收集患者的临床、手术及实验室资料,采用Logistic回归分析胸腰椎骨折合并脊髓损伤术后感染的影响因素,据此构建风险预测模型,以受试者工作特征(ROC)曲线分析风险模型对于胸腰段脊柱骨折合并脊髓损伤患者术后感染的预测价值。结果单因素结果显示,感染组和非感染组患者年龄[(67.23±5.26)岁vs.(60.21±4.25)岁]、糖尿病占比(62.69%vs.35.80%)、合并慢性阻塞性肺疾病(COPD)占比(73.13%vs.40.74%)、美国脊髓损伤协会损伤量表(ASIA)分级A级人数占比(47.76%vs.14.81%)、ASIA分级D级人数占比(5.97%vs.38.27%)、留置导尿占比(53.73%vs.27.16%)、间歇导尿占比(46.27%vs.73.84%)、血清C反应蛋白(CRP)[(57.85±9.72)mg/L vs.(44.84±10.22)mg/L]、降钙素原[(0.37±0.08)μg/L vs.(0.23±0.07)μg/L]比较,差异均有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,糖尿病、合并COPD、留置导尿、高龄、血清CRP、降钙素原水平升高是胸腰椎骨折合并脊髓损伤术后感染的独立危险因素(P<0.05),其中ASIA分级高为胸腰椎骨折合并脊髓损伤术后感染的保护因素(P<0.05)。胸腰椎骨折合并脊髓损伤术后感染的风险预测模型ROC曲线下面积为0.982(95%CI:0.956~1.000),敏感度为95.522%、特异度为97.531%。结论胸腰椎骨折合并脊髓损伤术后感染与糖尿病、合并COPD、留置导尿、高龄、血清CRP、降钙素原水平升高等多种因素相关,其中ASIA分级高为其保护因素,同时据此风险因素构建的风险预测模型具有较好的预测效能。 展开更多
关键词 胸腰椎骨折 脊髓损伤 术后感染 危险因素 预测模型
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儿童无骨折脱位型脊髓损伤特异性脑白质纤维束改变-基于白质骨架的弥散定量分析
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作者 郑卫敏 王玲 +3 位作者 杨贝宁 李坤成 卢洁 陈楠 《医学影像学杂志》 2024年第8期1-6,共6页
目的 探讨儿童无骨折脱位型脊髓损伤(SCIWOFD)患者脑白质纤维束的特异性改变。方法 选取25例儿童SCIWOFD患者(SCIWOFD组)及27例年龄、性别相匹配的正常发育儿童(对照组)的弥散张量成像(DTI)数据,利用基于白质纤维骨架的空间统计学方法(T... 目的 探讨儿童无骨折脱位型脊髓损伤(SCIWOFD)患者脑白质纤维束的特异性改变。方法 选取25例儿童SCIWOFD患者(SCIWOFD组)及27例年龄、性别相匹配的正常发育儿童(对照组)的弥散张量成像(DTI)数据,利用基于白质纤维骨架的空间统计学方法(TBSS)分析两组之间脑白质纤维束的差异,并进一步量化分析儿童SCIWOFD患者脑白质纤维束改变与临床指标之间的相关性,最后采用受试者工作特征曲线(ROC)分析,计算利用TBSS进行儿童SCIWOFD诊断的敏感性和特异性。结果 与HCs相比,儿童SCIWOFD患者右侧上纵束、左侧胼胝体压部和右侧内囊后肢的各向异性分数(FA)显著增加,平均扩散率(MD)、纵向弥散率(RD)显著减低,未发现DTI相关指标与感觉运动评分、患者年龄、病程之间的显著相关性。在使用右侧上纵束的FA值作为两组样本的分类指标时,其曲线下面积(AUC)达到了0.903。结论 儿童SCIWOFD患者存在显著的脑白质纤维束改变,同时TBSS作为儿童SCIWOFD筛查工具具有一定的潜力,并为未来的康复治疗提供了新视角。 展开更多
关键词 儿童无骨折脱位型脊髓损伤 基于白质纤维骨架的空间统计方法 脑白质纤维束 受试者工作特征曲线分析 磁共振成像
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无骨折脱位型颈脊髓损伤的病理机制与治疗进展 被引量:2
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作者 段韩磊(综述) 强京灵(审校) 《中国临床神经外科杂志》 2024年第1期49-53,共5页
无骨折脱位型颈脊髓损伤(CSCIWFD)是一种特殊类型的脊髓损伤,在临床中并不少见。病人虽然具有颈脊髓损伤的临床症状,但X线、CT检查却没有骨折脱位等影像学表现,很容易被临床医生误诊,从而影响后续诊疗。本文就CSCIWFD的损伤机制、临床... 无骨折脱位型颈脊髓损伤(CSCIWFD)是一种特殊类型的脊髓损伤,在临床中并不少见。病人虽然具有颈脊髓损伤的临床症状,但X线、CT检查却没有骨折脱位等影像学表现,很容易被临床医生误诊,从而影响后续诊疗。本文就CSCIWFD的损伤机制、临床表现、病理生理特点、分型及目前治疗进展进行综述,为临床提供参考,以使CSCIWFD病人可以得到早期准确的诊断,降低漏诊率,早期得到有效的治疗,改善病人的预后。 展开更多
关键词 脊髓损伤 无骨折脱位型颈脊髓损伤 发病机制 治疗进展
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不稳定支撑面核心稳定性训练对胸腰段脊柱骨折伴不完全性脊髓损伤患者的康复疗效
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作者 梁俊豪 陈罗西 +2 位作者 刘付龙 刘思源 赖华兵 《中国医药》 2024年第10期1520-1525,共6页
目的探讨不稳定支撑面核心稳定性训练(CST)对胸腰段脊柱骨折伴不完全性脊髓损伤(ISCI)患者的康复疗效。方法选取2019年1月至2022年12月于四川省骨科医院行康复治疗的96例胸腰段脊柱骨折伴ISCI患者,应用随机数字表法分为A组和B组,各48例... 目的探讨不稳定支撑面核心稳定性训练(CST)对胸腰段脊柱骨折伴不完全性脊髓损伤(ISCI)患者的康复疗效。方法选取2019年1月至2022年12月于四川省骨科医院行康复治疗的96例胸腰段脊柱骨折伴ISCI患者,应用随机数字表法分为A组和B组,各48例。2组均接受坐位及卧位的CST,A组在不稳定支撑面(训练球)上训练,B组在稳定支撑面(训练床)上训练,均连续训练8周。分别于训练前和训练后10周,评估美国脊柱损伤协会脊髓损伤分级(ASIA)改善效果;分别于训练前和训练后2、4、6、8、10周,采用脊髓功能独立性评分(SCIM)、功能独立性测定评分(FIM)和脊髓损伤步行指数Ⅱ量表(WISCIⅡ)评分评估2组脊髓功能恢复情况;评估2组立位姿势控制能力和静态平衡能力,复查X线片检查伤椎矢状位Cobb′s角。结果训练后10周,A组B、C、D级分别为8、23、17例,B组分别为11、30、7例,A组ASIA分级改善效果均优于B组(P<0.05)。训练后4、6、8、10周,A组SCIM、FIM和WISCIⅡ评分均高于B组(均P<0.05);A组静态睁眼轨迹长度、静态闭眼轨迹长度、单位时间轨迹长度、动态稳定轨迹长度和动态达目的时间均长于B组(均P<0.05);A组各时间点Cobb′s角均明显小于B组(均P<0.05)。结论不稳定支撑面CST可显著改善胸腰椎脊柱骨折伴ISCI患者脊髓残损修复和步行功能,可在无视觉反馈帮助下有效促进患者立位姿势控制能力。 展开更多
关键词 不稳定支撑面 核心稳定性训练 胸腰段脊柱骨折 不完全性脊髓损伤 康复疗效
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医护一体手术室综合管理预防脊柱骨折伴脊髓损伤患者术中压力性损伤的效果分析
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作者 靳丽娟 汪红英 《河北医药》 CAS 2024年第17期2638-2642,共5页
目的分析医护一体手术室综合管理预防脊柱骨折伴脊髓损伤患者术中压力性损伤的效果。方法选择2019年12月至2022年7月接受手术的脊柱骨折伴脊髓损伤患者116例,按随机数表法分为对照组(58例,接受围术期常规管理)和研究组(58例,开展围术期... 目的分析医护一体手术室综合管理预防脊柱骨折伴脊髓损伤患者术中压力性损伤的效果。方法选择2019年12月至2022年7月接受手术的脊柱骨折伴脊髓损伤患者116例,按随机数表法分为对照组(58例,接受围术期常规管理)和研究组(58例,开展围术期常规管理+医护一体手术室综合管理)。统计2组术后压力性损伤发生率、发生程度、发生部位与损伤面积,观察患者管理前、管理后心理弹性、创伤后成长、功能独立性、脊髓功能、感觉与运动水平的变化,记录2组围术期并发症。结果研究组压力性损伤发生率为3.45%低于对照组的15.52%(P<0.05);研究组压力性损伤发生程度轻于对照组(P<0.05);2组压力性损伤发生部位、并发症发生率差异无统计学意义(P>0.05);研究组术后当天、术后3 d的压力性损伤面积低于对照组(P<0.05);研究组管理后心理弹性量表(CD-RISC)、创伤后成长自评量表(PTGI)、功能独立性评定量表(FIM)评分均高于对照组(P<0.05);研究组脊髓独立性评定量表中文版(SCIMⅢ)、国际脊髓损伤神经评分标准(ASIA)中的ASIA感觉功能评分(SS)、ASIA运动功能评分(MS)评分均高于对照组(P<0.05)。结论脊柱骨折伴脊髓损伤患者接受医护一体手术室综合管理可有效预防或减少术中压力性损伤发生,提高心理弹性与创伤后成长水平,改善功能独立性、脊髓功能。 展开更多
关键词 脊柱骨折 脊髓损伤 医护一体手术室综合管理 压力性损伤
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信息-动机-行为技巧模式下集束化干预方案在脊柱骨折合并脊髓损伤患者中的应用效果
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作者 荣原 梁云云 +1 位作者 项蕾蕾 殷颖 《中国医药导报》 CAS 2024年第17期132-135,共4页
目的 探究信息-动机-行为技巧(IMB)模式下集束化干预方案在脊柱骨折合并脊髓损伤患者中的应用效果。方法 选取2020年5月至2023年5月江苏省淮安市第一人民医院118例脊柱骨折合并脊髓损伤患者作为研究对象,按信封抽签法分为常规组和IMB组,... 目的 探究信息-动机-行为技巧(IMB)模式下集束化干预方案在脊柱骨折合并脊髓损伤患者中的应用效果。方法 选取2020年5月至2023年5月江苏省淮安市第一人民医院118例脊柱骨折合并脊髓损伤患者作为研究对象,按信封抽签法分为常规组和IMB组,各59例。常规组实施常规护理干预,IMB组在常规护理的基础上实施IMB模式下集束化干预。比较两组干预前和干预1个月后的干预效果、生活质量、心理弹性、创伤后成长及并发症情况。结果 干预前,两组干预效果、生活质量、心理弹性、创伤后成长比较,差异无统计学意义(P>0.05);干预后,两组触觉评分、运动评分、椎体相对高度高于干预前,且IMB组高于常规组,差异有统计学意义(P<0.05);两组Cobb’s角均小于干预前,且IMB组小于常规组,差异有统计学意义(P<0.05);两组生活质量评分高于干预前,且IMB组高于常规组,差异有统计学意义(P<0.05);两组心理弹性量表各项评分均高于干预前,且IMB组高于常规组,差异有统计学意义(P<0.05);两组创伤后成长量表各项评分均高于干预前,且IMB组高于常规组,差异有统计学意义(P<0.05);IMB组并发症总发生率低于常规组,差异有统计学意义(P<0.05)。结论 IMB模式下集束化干预方案在脊柱骨折合并脊髓损伤患者中的应用效果较为显著。 展开更多
关键词 信息-动机-行为技巧模式 集束化护理 脊柱骨折合并脊髓损伤 干预效果
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