A water-soluble oligo(p-phenylkene vinylene) [4,4′-(1,4-phenylene dithenylene)-bis-(N-methyl pyridinium iodide)] was synthesized by Witting reaction. The oligomer was characterized by NMR, elemental analysis, UV-visi...A water-soluble oligo(p-phenylkene vinylene) [4,4′-(1,4-phenylene dithenylene)-bis-(N-methyl pyridinium iodide)] was synthesized by Witting reaction. The oligomer was characterized by NMR, elemental analysis, UV-visible spectrum, surface photovoltage spectrum and fluorescence spectrum.展开更多
The incorporation of mechanophores,motifs that transform mechanical stimulus into chemical reaction or optical variation,allows creating materials with stressresponsive properties.The most widely used mechanophore gen...The incorporation of mechanophores,motifs that transform mechanical stimulus into chemical reaction or optical variation,allows creating materials with stressresponsive properties.The most widely used mechanophore generally features a weak bond,but its cleavage is typical an irreversible process.Here,we showed that this problem can be solved by folding–unfolding of a molecular tweezer.We systematically studied the mechanochromic properties of polyurethanes with cyano-substituted oligo(p-phenylene)vinylene(COP)tweezer(DPU).As a control experiment,a class of polyurethanes containing only a single COP moiety(MPU)was also prepared.The DPU showed prominent mechanochromic properties,due to the intramolecular folding–unfolding of COP tweezer under mechanical stimulus.The process was efficient,reversible and optical detectable.However,due to the disability to form either intramolecular folding or intermolecular aggregation,the MPU sample was mechanical inert.展开更多
The oligo phenylene vinylene(oligo PV)/SiO 2 composite film was prepared by the sol gel process. The surface photovoltage spectroscopy(SPS) and electric field induced surface photovoltage spectroscopy(EFISPS) had been...The oligo phenylene vinylene(oligo PV)/SiO 2 composite film was prepared by the sol gel process. The surface photovoltage spectroscopy(SPS) and electric field induced surface photovoltage spectroscopy(EFISPS) had been used to investigate the charge transport process in olige PV/SiO 2 heterostructured composite. The results show that the oligo PV / SiO 2 composite film not only can improve the stability of oligo PV, but also have some photoelectric activity.展开更多
Recently,photodynamic therapy(PDT)has attracted wide attention due to its less susceptibility to drug resistance,broad-spectrum biocidal activity and biosafety in normal tissues.However,the traditional photosensitizer...Recently,photodynamic therapy(PDT)has attracted wide attention due to its less susceptibility to drug resistance,broad-spectrum biocidal activity and biosafety in normal tissues.However,the traditional photosensitizers(Ps)face the disadvantage of poor therapeutic efficacy due to the requirement of an aerobic environment to generate ^(1)O_(2) through Type Ⅱ pathway.Herein,we designed and synthesized a novel cationic conjugated oligomer oligo(phenylene vinylene)(OPV)and studied its antibacterial photodynamic activity against both Gram-negative Escherichia coli(E.coli)and Gram-positive bacteria methicillin-resistant Staphylococcus aureus(MRSA).Importantly,the OpV can rapidly produce reactive oxygen species(ROs)through double pathways,Type Ⅰ and Ⅱ mechanism under white light irradiation,and efficiently kill E.coli and MRSA at a nanomolar level.The dual type photosensitizing capability makes OPV promising for enhanced PDT to treat pathogens and tumors in complex environments.展开更多
基金supported by the Major Basic Research Project(Grant No.2002CB613401)the Foundation of Jilin university.
文摘A water-soluble oligo(p-phenylkene vinylene) [4,4′-(1,4-phenylene dithenylene)-bis-(N-methyl pyridinium iodide)] was synthesized by Witting reaction. The oligomer was characterized by NMR, elemental analysis, UV-visible spectrum, surface photovoltage spectrum and fluorescence spectrum.
基金This work was financially supported by the National Natural Science Foundation of China(Grant Nos.52103141 and 51803090)the Natural Science Foundation of Jiangsu Province(Grant Nos.BK20181025 and BK20191022)for financial support.
文摘The incorporation of mechanophores,motifs that transform mechanical stimulus into chemical reaction or optical variation,allows creating materials with stressresponsive properties.The most widely used mechanophore generally features a weak bond,but its cleavage is typical an irreversible process.Here,we showed that this problem can be solved by folding–unfolding of a molecular tweezer.We systematically studied the mechanochromic properties of polyurethanes with cyano-substituted oligo(p-phenylene)vinylene(COP)tweezer(DPU).As a control experiment,a class of polyurethanes containing only a single COP moiety(MPU)was also prepared.The DPU showed prominent mechanochromic properties,due to the intramolecular folding–unfolding of COP tweezer under mechanical stimulus.The process was efficient,reversible and optical detectable.However,due to the disability to form either intramolecular folding or intermolecular aggregation,the MPU sample was mechanical inert.
文摘The oligo phenylene vinylene(oligo PV)/SiO 2 composite film was prepared by the sol gel process. The surface photovoltage spectroscopy(SPS) and electric field induced surface photovoltage spectroscopy(EFISPS) had been used to investigate the charge transport process in olige PV/SiO 2 heterostructured composite. The results show that the oligo PV / SiO 2 composite film not only can improve the stability of oligo PV, but also have some photoelectric activity.
基金financial support from the National Natural Science Foundation of China(Grants 21974084,22274095 and 22101310)Innovation Capability Support Program of Shaanxi(Program no.2021TD-42)Fundamental Research Funds for the Central Universities(No.GK202302004,GK202207013,and GK202101001).
文摘Recently,photodynamic therapy(PDT)has attracted wide attention due to its less susceptibility to drug resistance,broad-spectrum biocidal activity and biosafety in normal tissues.However,the traditional photosensitizers(Ps)face the disadvantage of poor therapeutic efficacy due to the requirement of an aerobic environment to generate ^(1)O_(2) through Type Ⅱ pathway.Herein,we designed and synthesized a novel cationic conjugated oligomer oligo(phenylene vinylene)(OPV)and studied its antibacterial photodynamic activity against both Gram-negative Escherichia coli(E.coli)and Gram-positive bacteria methicillin-resistant Staphylococcus aureus(MRSA).Importantly,the OpV can rapidly produce reactive oxygen species(ROs)through double pathways,Type Ⅰ and Ⅱ mechanism under white light irradiation,and efficiently kill E.coli and MRSA at a nanomolar level.The dual type photosensitizing capability makes OPV promising for enhanced PDT to treat pathogens and tumors in complex environments.
