Committed to Safe Production China-Indonesia joint venture HBAP strives to ensure safe, stable operations while fulfilling social responsibility

Recently,PT Huadian Bukit Asam Power (HBAP) was awarded the"Zero Accident Award"by the Ministry of Manpower of the Republic of Indonesia.This national-level award for safe production in Indonesia serves to testify to the enterprise's achievements in safe and stable operations from June 1,2018,to December 31,2023.

基于SPO理论的医院抗菌药物管理体系应用探讨

“抗菌药物使用强度”是三级公立医院绩效考核核心指标之一。基于结构-过程-结果(SPO)理论构建抗菌药物管理体系,通过建章立制明确各方职责,科学制订用药规则,依托信息化高效整合抗菌药物事前、事中、事后管理,某院抗菌药物使用强度从2020年57.8DDDs下降到2022年31.1DDDs。SPO理论有助于抗菌药物全方位闭环管理,但需充分发挥临床药师专业价值和纽带作用。

基于SPO理论多维度药学服务的实践与探讨

医院合理用药管理是三级公立医院绩效考核的重点内容之一。中山大学附属第一医院惠亚医院以三级公立医院绩效考核为指挥棒,基于SPO理论构建了多维度药学服务模式,从结构维度成立管理组织、统一管理制度、细化考核指标以优化合理用药管控体系,从过程维度依托信息化建设、多层次药学服务干预以加强临床合理用药监管,从结果维度动态监测、分析药学指标以加强质量控制考评与持续改进。中山大学附属第一医院惠亚医院通过开展基于SPO理论多维度药学服务实践,实施合理用药管控,促进药物合理使用,优化医疗收支结构,控制药品费用增长,在国家三级公立医院绩效考核工作中发挥积极作用,并为药学服务转型发展提供参考。

基于SPO理论框架的分院区同品质医疗实施路径探索

分院区建设是配置优质医疗资源的重要方式之一,而医疗同质化是分院区管理的核心难题。受制于学科、人员、监管、信息化等的不同质,分院区往往难以提供与主院区相同品质的医疗服务。阐述了某大型委属(管)医院在一院四区建设中基于SPO理论框架实施同品质医疗的路径及举措,以结构、过程、结果3个维度,在重点要素配置、全面全程监管、评估提升改进等的具体实践中探讨不同类型的分院区医疗管理策略,以期为分院区建设提供参考。

基于改进功能共振分析法的SPO风险演化

为充分识别单一飞行员运行(SPO)模式下各子系统要素间的交互关系和耦合作用,梳理风险演化机制,使用改进功能共振分析法(FRAM)构建定量分析模型。采用模糊综合评判法评估系统功能模块的功能可变性;引入结构重要性概念,分析计算系统功能模块的上下游耦合变异性,厘清系统各功能要素间耦合作用影响机制;针对SPO特定场景案例,应用蒙特卡罗模拟法计算功能共振风险指数,分析潜在功能共振情况,并设置有效功能屏障。结果表明:改进的FRAM法可以解释SPO的非线性耦合情况,空中交通管制服务、飞行员认知状态、机长操纵等模块的功能可变性耦合变化指数较大,均超过2.5;进近着陆场景中机组技术培训、重要气象信息、空中交通管制服务、地面信息保障等8个功能容易出现功能共振情况;结合功能共振结果,设置物理、象征、功能、隐形种功能安全屏障措施,并以此得出针对性运行保障建议。

基于SPO理论的健康促进医院建设评价指标体系构建

健康促进医院建设是一项系统性有机整体,以提升全人群健康素养和健康水平为目的,应用健康促进的理论、理念和策略,建立以病患需求和以人民健康为中心的医疗健康服务系统,为员工、患者、社区居民等提供一个良性互动、互相促进的健康组织。目前我国的健康促进医院建设仍处于探索完善阶段,文章以SPO理论为依据,将健康促进医院评价分为结构、过程和结果三个维度,运用层次分析法(AHP)构建包含6个一级指标和21个二级指标的评价指标体系,以期为健康促进医院建设的规范化、高质量发展提供科学、合理、可操作的评价指标体系,也为健康促进医院的管理和质量改进提供指导依据。

基于SPO模型的定点医疗机构医保合规管理路径探析

为有力打击我国定点医疗机构违规使用、骗取医保基金等行为,提高我国定点医疗机构的医保合规管理能力,本文运用SPO模型,提出构建以“结构(structure)—过程(process)—结果(outcome)”为核心的定点医疗机构医保合规管理体系。建议在结构管理上,设立定点医疗机构医保合规的规章制度及组织架构;在精细化管理过程中,完善“事前提醒—事中监管—事后分析”全流程医保合规运行机制;在结果管理上,建立医保监管平台数据及医患双方医保使用满意度调查反馈机制。本文认为构建定点医疗机构医保合规管理机制能推动我国医保基金管理实现被动监管与主动合规的结合,有利于保障我国医保基金的安全稳定。

基于系统论SPO模型构建医院内部质量评价体系的实践体会

目的通过介绍基于系统论SPO模型构建医院内部质量评价体系的实践经验,为医疗机构内部质量评价提供借鉴和参考。方法基于SPO模型,从结构维度、过程维度和结果维度梳理医院内部质量评价管理实践经验。结果2020—2022年医院职能部门管理成效有所提升,医院优先级指标明显改善,患者满意度稳步提高。结论医院内部质量评价作为外部评价的重要补充,有助于医院内部质量管理长效机制的建立,而系统论SPO模型有利于理清医院管理活动实践的思路。基于SPO模型构建医院内部质量评价体系并付诸实施,有利于医院管理效能的提升,值得推广应用。

基于“MOOC+SPOC”的旅游管理专业课教学模式与改进策略研究——以旅游景区经营与管理课程为例

旅游景区经营与管理课程实施混合式教学模式后,课堂出勤质量稳步改善,课堂发言有序增加,作业质量大幅提高,文明素养明显增长。为了取得更优质的教学效果,应综合采取多种策略:健全课程考核体系,激发学生内在动力;丰富平台资源类型,优化线上资源结构;熟练运用平台功能,提高线上教学成效;线下课堂走进景区,落实行知教育理念;优化课程内容结构,培养学生行业认同。

罗氏沼虾Spo11基因克隆、表达及其在卵巢发育中的作用

为研究减数分裂相关基因Spo11(meiotic protein covalently bound to DSB homolog)在罗氏沼虾(Macrobrachium rosenbergii)卵巢发育中的调控作用,采用RACE技术、荧光定量PCR、原位杂交和RNA干扰等方法,对罗氏沼虾Spo11基因(MrSpo11)及其编码氨基酸的分子特征、MrSpo11基因的组织表达、分布和生物学功能进行了研究。结果表明:MrSpo11基因cDNA序列全长为2298 bp,其中,5′端和3′端非编码区分别为457、701 bp,开放阅读框为1140 bp,共编码379个氨基酸残基;MrSpo11基因在罗氏沼虾鳃中的相对表达量最高,在卵巢、肝胰腺和心脏中表达量较高,在脑、眼和肌肉中微量表达;MrSpo11基因在罗氏沼虾卵巢发育Ⅰ期相对表达量最高,在卵巢发育Ⅲ期次之,在Ⅱ期和Ⅳ期表达量最低;MrSpo11基因在卵黄发生前期、中期、晚期卵母细胞的细胞质,以及卵黄发生早期卵母细胞的细胞质和细胞核中均有表达;注射dsRNA后第2、4天,试验组MrSpo11基因的表达量分别比对照组下降45.8%、11.6%,注射dsRNA后第4天,试验组卵巢发育成熟度略低于对照组。研究表明,MrSpo11基因参与了罗氏沼虾卵巢发育过程,本研究结果可为进一步探究罗氏沼虾卵巢发育分子调控机制提供有益参考。

Porous-DeepONet:Learning the Solution Operators of Parametric Reactive Transport Equations in Porous Media

Reactive transport equations in porous media are critical in various scientific and engineering disciplines,but solving these equations can be computationally expensive when exploring different scenarios,such as varying porous structures and initial or boundary conditions.The deep operator network(DeepONet)has emerged as a popular deep learning framework for solving parametric partial differential equations.However,applying the DeepONet to porous media presents significant challenges due to its limited capability to extract representative features from intricate structures.To address this issue,we propose the Porous-DeepONet,a simple yet highly effective extension of the DeepONet framework that leverages convolutional neural networks(CNNs)to learn the solution operators of parametric reactive transport equations in porous media.By incorporating CNNs,we can effectively capture the intricate features of porous media,enabling accurate and efficient learning of the solution operators.We demonstrate the effectiveness of the Porous-DeepONet in accurately and rapidly learning the solution operators of parametric reactive transport equations with various boundary conditions,multiple phases,and multiphysical fields through five examples.This approach offers significant computational savings,potentially reducing the computation time by 50–1000 times compared with the finite-element method.Our work may provide a robust alternative for solving parametric reactive transport equations in porous media,paving the way for exploring complex phenomena in porous media.

基于SPO模型的智慧医院信息化项目风险防控实践

文中介绍了上海交通大学医学院附属上海儿童医学中心在智慧医院信息化项目实施过程中风险防控的实践经验,通过从结构维度科学谋划顶层设计、从过程维度保障有序推进、从结果维度开展模型实施效果评估,构建了医院信息化项目风险管理参考模型.模型应用后,智慧医院信息化项目完成率由2020—2021年的94.0%上升至2022—2023年的99.3%,项目完成率较模型应用前有所提升,差异具有统计学意义(P=0.01).基于SPO模型的风险防控,确保信息化项目按计划有序推进,减少项目风险损失,有效提升患者满意度以及医院服务管理能力,为其他医疗机构实施智慧医院提供借鉴和参考.

Effects of spot size on the operation mode of Ga As photoconductive semiconductor switch employing extrinsic photoconductivity

To guide the illuminating design to improve the on-state performances of gallium arsenide(GaAs)photoconductive semiconductor switch(PCSS),the effect of spot size on the operation mode of GaAsPCSS based on a semi-insulating wafer with a thickness of 1 mm,triggered by a 1064-nm extrinsic laser beam with the rectangular spot,has been investigated experimentally.It is found that the variation of the spot size in length and width can act on the different parts of the output waveform integrating the characteristics of the linear and nonlinear modes,and then significantly boosts the PCSS toward different operation modes.On this basis,a two-channel model containing the active and passive parts is introduced to interpret the relevant influencing mechanisms.Results indicate that the increased spot length can peak the amplitude of static domains in the active part to enhance the development of the nonlinear switching,while the extended spot width can change the distribution of photogenerated carriers on both parts to facilitate the linear switching and weaken the nonlinear switching,which have been proved by comparing the domain evolutions under different spot sizes.

Case Report: Surgical Correction of Transposition of the Great Arteries with Aortopulmonary Window

Introduction:Transposition of the great arteries(TGA)with aortopulmonary window is a rare type of congenital heart disease with limited experience.We reported a neonate aged 25 days receiving the arterial switch operation and assisted with extracorporeal membrane oxygenation.Conclusion:TGA with aortopulmonary window can be safely correctly with the arterial switch operation.

Aero-Hydro-Elastic-Servo Modeling and Dynamic Response Analysis of A Monopile Offshore Wind Turbine Under Different Operating Scenarios

This paper constructs a coupled aero-hydro-elastic-servo simulation framework for a monopile offshore wind turbine(OWT).In this framework,a detailed multi-body dynamics model of the monopile OWT including the gearbox,blades,tower and other components(nacelle,hub,bedplate,etc.)has been explicitly established.The effects of pile−soil interaction,controller and operational conditions on the turbine dynamic responses are studied systematically in time domain and frequency domain.The results show that(1)a comprehensive drivetrain model has the capability to provide a more precise representation of the complex dynamic characteristics exhibited by drivetrain components,which can be used as the basis for further study on the dynamic characteristics of the drivetrain.(2)The pile−soil interaction can influence the wind turbine dynamic responses,particularly under the parked condition.(3)The effect of the pile−soil interaction on tower responses is more significant than that on blade responses.(4)The use of the controller can substantially affect the rotor characteristics,which in turn influences the turbine dynamic responses.(5)The tower and blade displacements under the operational condition are much larger than those under the parked condition.The model and methodology presented in this study demonstrate potential for examining complex dynamic behaviors of the monopile OWTs.To ensure accuracy and precision,it is imperative to construct a detailed model of the wind turbine system,while also taking into account simulation efficiency.

A 63-Year-Old Male with D-Transposition of the Great Arteries Who Had an Early Form of the Arterial Switch Operation

We describe a 63-year-old male who appears to have undergone an early form of the arterial switch operation for D-transposition of the great arteries performed in the mid-1960s.We review the clinical and imaging data that support our conclusion.He had a diagnostic cardiac catheterization which demonstrated severe pulmonary hypertension responsive to epoprostenol and oxygen.Our case may represent one example of the experimental surgical work done prior to Dr.Adibe Jatene’s description of thefirst successful arterial switch performed in 1975.

Evaluation of Driver-Induced Human Errors in Smart Construction Tower Crane Operations Based on DEMATEL-ISM-MICMAC

With the advent of Industry 4.0, smart construction sites have seen significant development in China. However, accidents involving digitized tower cranes continue to be a persistent issue. Among the contributing factors, human unsafe behavior stands out as a primary cause for these incidents. This study aims to assess the human reliability of tower crane operations on smart construction sites. To proactively enhance safety measures, the research employs text mining techniques (TF-IDF-Truncated SVD-Complement NB) to identify patterns of human errors among tower crane operators. Building upon the SHEL model, the study categorizes behavioral factors affecting human reliability in the man-machine interface, leading to the establishment of the Performance Shaping Factors (PSFs) system. Furthermore, the research constructs an error impact indicator system for the intelligent construction site tower crane operator interface. Using the DEMATEL method, it analyzes the significance of various factors influencing human errors in tower crane operations. Additionally, the ISM-MICMAC method is applied to unveil the hierarchical relationships and driving-dependent connections among these influencing factors. The findings indicate that personal state, operating procedures, and physical environment directly impact human errors, while personal capability, technological environment, and one fundamental organizational management factor contribute indirectly. .

Research and Practice of the Blended Teaching Model of BOPPPS Teaching Method Under the Background of Digital Education: Taking Operations Research Course as an Example

The rapid development of digital education provides new opportunities and challenges for teaching model innovation.This study aims to explore the application of the BOPPPS(Bridge-in,Objective,Pre-assessment,Participatory learning,Post-assessment,Summary)teaching method in the development of a blended teaching model for the Operations Research course under the background of digital education.In response to the characteristics of the course and the needs of the student group,the teaching design is reconstructed with a student-centered approach,increasing practical teaching links,improving the assessment and evaluation system,and effectively implementing it in conjunction with digital educational technology.This teaching model has shown significant effectiveness in the context of digital education,providing valuable experience and insights for the innovation of the Operations Research course.

短短芽胞杆菌B011基因组中芽胞形成调控基因spo0E的鉴定与表达分析

短短芽胞杆菌B011是一株具有广谱抗菌活性的植物内生菌,发酵后期形成芽胞。据报道,芽胞形成调控基因Spo0E的编码产物能对Spo0A~P蛋白因子去磷酸化,从而实现芽胞形成的负调控。为了能够进一步验证B011基因组中Spo0E基因的功能和表达情况,为B011菌株的遗传改造提供候选基因,本研究基于B011全基因组序列,通过生物信息学工具预测得到了9个spo0E类似基因,并与其他已公布全基因组序列的101个短芽胞杆菌Brevibacillus菌株进行比较,结果表明短短芽胞杆菌spo0E家族基因在物种分化前就已经存在。转录组测序结果表明,FO446_19435和FO446_04050两个spo0E家族基因在B011中高表达,表达模式表现为先升高,在发酵18 h达到最高,此后下降,这两个基因均存在SQELD基序,推测这两个基因为B011中的两个主效spo0E基因。研究结果可为短短芽胞杆菌B011的进一步开发和利用提供一定的基础。

基于SPO模型的控烟条例实施效果评价指标体系构建及应用研究

目的基于SPO(结构-过程-结果)模型构建《杭州市公共场所控制吸烟条例》实施效果评价指标体系,并以杭州市作为实证研究区域评价其新版《杭州市公共场所控制吸烟条例》的实际执行效果,为其他城市的无烟建设提供理论参考。方法采用德尔菲专家咨询法确定指标体系,通过层次分析法、均数法、连乘累计组合赋权法计算各级指标的权重,并使用所构建的指标体系对杭州市所辖区县的控烟实施效果进行评价。结果共邀请到17位专家和学者全程参与德尔菲专家咨询,2轮专家的积极系数分别为90.00%、94.44%,权威系数Cr分别为0.89、0.91;专家意见的协调系数分别为0.183和0.249;最终确定的指标体系重要性均数均>3.5,CV为0.07~0.21,CR均<0.1,专家意见趋于一致。经过2轮专家咨询,最终构建的指标体系包括3项一级指标、11项二级指标、41项三级指标。根据所构建的指标体系对杭州市11个区县的控烟实施效果进行评价,经百分制换算后二级指标得分最高分为89.66,最低分为26.05,各区县间总得分差距明显,其中,不同区县间管理支持、物力和人力资源、条例的宣传、监督执法、公众参与的得分差异具有统计学意义(P<0.05)。结论本研究所构建的《杭州市公共场所控制吸烟条例》实施效果评价指标体系具有科学性、合理性,适用于评价区域控烟条例的实施效果,能为其他城市无烟政策的实施效果评价提供理论参考。