Dear Editor,Hydroxychloroquine(HCQ)is a drug widely used in the treatment of autoimmune diseases and oncologic disorders,and was even used during a brief period of time for the therapy of COVID-19 disease[1].HCQ retin...Dear Editor,Hydroxychloroquine(HCQ)is a drug widely used in the treatment of autoimmune diseases and oncologic disorders,and was even used during a brief period of time for the therapy of COVID-19 disease[1].HCQ retinopathy has a prevalence ranging from 4.3%to 13.8%.However,for a patient with a normal screening examination the risk of developing HCQ retinopathy is very low[2].The American Academy of Ophthalmology recommended visual field(VF)and optical coherence tomography(OCT)for the screening,whereas the Royal College of Ophthalmologists advised the use of OCT and fundus autofluorescence(FAF)[2-3].展开更多
Safety profile of 0.0015%tafluprost eye drops in China:a post-marketing observational study Xue-Li Chen,Yan-Jing Fu,Bo Qu,Ye-Wei Wang,Xin Tang,Yu-Hong Wang,Guo-Yi Zhou,Ming-Kai Lin,Jing-Yuan Shen,Jin Yao,Su-Yan Li,Mia...Safety profile of 0.0015%tafluprost eye drops in China:a post-marketing observational study Xue-Li Chen,Yan-Jing Fu,Bo Qu,Ye-Wei Wang,Xin Tang,Yu-Hong Wang,Guo-Yi Zhou,Ming-Kai Lin,Jing-Yuan Shen,Jin Yao,Su-Yan Li,Miao-Qin Wu,Hua-Zong Peng,Ming-Ying Lai,Ren-Yi Wu,Yi-Nong Zhang,Yan Li,Xiao-Jun Wu,Ming-Chang Zhang,Su-Ping Guo and Xing-Huai Sun(Int J Ophthalmol 2023;16(1):108-114.DOI:10.18240/ijo.2023.01.16)The authors would like to make the following change to the above article:The name of the second author Yan-Jing Fu should be modified as“Yan-Jiang Fu”.The authors apologize for any inconvenience caused by this error.展开更多
Posterior scleral application of a mitomycin C-soaked sponge during trabeculectomy Kun Hu,Yun-He Song,Feng-Bin Lin,Ying-Zhe Zhang,Ling Jin,Meng-Yin Liang,Robert N.Weinreb,Xiu-Lan Zhang(Int J Ophthalmol 2023;16(7):1071...Posterior scleral application of a mitomycin C-soaked sponge during trabeculectomy Kun Hu,Yun-He Song,Feng-Bin Lin,Ying-Zhe Zhang,Ling Jin,Meng-Yin Liang,Robert N.Weinreb,Xiu-Lan Zhang(Int J Ophthalmol 2023;16(7):1071-1077,doi:10.18240/ijo.2023.07.11)The authors would like to make the following change to the above article:“MMC was administered as a subconjunctival injection 0.02 mg/mL and 0.1 mL”on page 1073 should be changed to“MMC was administered as a subconjunctival injection 0.2 mg/mL and 0.1 mL”.展开更多
Purpose:</span></b><span style="font-family:""><span style="font-family:Verdana;"> Prospective study to evaluate the anti-inflammatory efficacy of isotonic seawater sol...Purpose:</span></b><span style="font-family:""><span style="font-family:Verdana;"> Prospective study to evaluate the anti-inflammatory efficacy of isotonic seawater solution on metalloproteinase 9 (MMP-9) levels in the tears of patients with dry eye disease (DED). </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> A total of 50 patients were included, with the following dry eye criteria in both eyes: InflammaDry</span></span><sup><span style="font-family:Verdana;">?</span></sup><span style="font-family:""><span style="font-family:Verdana;"> test initially positive, ocular surface disease index (OSDI) score ≥ 12 and <33, tear film breakup time (TBUT) ≤ 10 seconds, Shirmer I test result ≤ 10 mm/5 minutes, corneal staining ≥ 1. Additionally, all the patients selected corresponded to a dry eye type 2 - 3 severity degree - mild and moderate - Dry Eye Workshop Study (DEWS) classification. The InflammaDry test is used to measure levels of MMP9 at the beginning and the end of the study. All patients were treated exclusively with isotonic seawater solution 5 times a day for 3 weeks. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> The InflammaDry test was positive in 100% of the patients (n = 50) and in 100% (n = 100) of the eyes before treatment. In 14 (28%) patients the test became negative in both eyes, and in 15 (30%) it was negative in one of the eyes. In 43% (n = 43) of the positive eyes, MMP-9 became undetectable in the tear fluid following treatment with isotonic seawater. This change was statistically significant (p < 0.001). </span><b><span style="font-family:Verdana;">Conclusions</span></b><span style="font-family:Verdana;">: The washes with ophthalmic isotonic seawater solution have a significant impact on inflammation of the ocular surface in dry eye disease, with an ability to make MMP-9 levels negative in 43% of cases.展开更多
Dear Editor,I am Dr.Xian-Ning Liu,from the Institute of Ophthalmology of Xi’an First Hospital in Xi’an,Shaanxi Province,China.I write to present a case report of corneal ulcer caused by Schizophyllum commune(S.commu...Dear Editor,I am Dr.Xian-Ning Liu,from the Institute of Ophthalmology of Xi’an First Hospital in Xi’an,Shaanxi Province,China.I write to present a case report of corneal ulcer caused by Schizophyllum commune(S.commune).Mycotic keratitis is one of the most severe causes of corneal blindness in developing countries,such as China and India[1-2].展开更多
In order to understand the immune responses to lens protein in patients with congenital cataract, the passive hemagglutination assay for humoral immunity and the leukocyte migration test for cellular immunity to lens ...In order to understand the immune responses to lens protein in patients with congenital cataract, the passive hemagglutination assay for humoral immunity and the leukocyte migration test for cellular immunity to lens protein were performed on 43 patients with congenital cataract and 30 healthy persons served as control.The results showed that there was no significant difference in the incidence of humoral immune responses to lens protein between patients with congenital cataract and the controls (P】0.05), but the incidence of cellular immune responses tolensprotein in patients with congenital cataract was higher than that of the controls (P【0.005).The results of this study suggested that during the development of congenital cataract, lens protein leaked into the aqueous humour and entered the systemic circulation, sensitizing lymphocytes and producing cellular mediated immune responses. Further investigation is neceessary to determine whether there is any relationship between the immune responses to lens protein and the formation of congenital cataract.展开更多
9714873 眼外伤的标准化分类法/KuhnF//J Am Acad Ophthalmol.-1995,103(2).-240～243 北医图9714874 上斜眼和后部冲击性骨折:机制和处理/Seiff S R//J Am Acad Ophthal-mol.-1995,103(1).-152～156 北医图9714875 挨打妇女的眼外伤/Be...9714873 眼外伤的标准化分类法/KuhnF//J Am Acad Ophthalmol.-1995,103(2).-240～243 北医图9714874 上斜眼和后部冲击性骨折:机制和处理/Seiff S R//J Am Acad Ophthal-mol.-1995,103(1).-152～156 北医图9714875 挨打妇女的眼外伤/Beck S R//J Am Acad Ophthalmol.-1995,103(1).-148～151展开更多
To the Editor:A 4-month-old girl was brought to the Department of Ophthalmology in the Children’s Hospital,School of Medicine,Zhejiang University,due to"sudden eyeball shaking for a week."The patient was a ...To the Editor:A 4-month-old girl was brought to the Department of Ophthalmology in the Children’s Hospital,School of Medicine,Zhejiang University,due to"sudden eyeball shaking for a week."The patient was a full-term gravida 2 para 2 infant without any incidence of trauma/surgery;further,the family’s medical history did not reveal any risk factors.Ophthalmological examination revealed bilateral horizontal tremor of the eyes,and both eyes showed light-chasing response.The anterior segment examination was normal.展开更多
文摘Dear Editor,Hydroxychloroquine(HCQ)is a drug widely used in the treatment of autoimmune diseases and oncologic disorders,and was even used during a brief period of time for the therapy of COVID-19 disease[1].HCQ retinopathy has a prevalence ranging from 4.3%to 13.8%.However,for a patient with a normal screening examination the risk of developing HCQ retinopathy is very low[2].The American Academy of Ophthalmology recommended visual field(VF)and optical coherence tomography(OCT)for the screening,whereas the Royal College of Ophthalmologists advised the use of OCT and fundus autofluorescence(FAF)[2-3].
文摘Safety profile of 0.0015%tafluprost eye drops in China:a post-marketing observational study Xue-Li Chen,Yan-Jing Fu,Bo Qu,Ye-Wei Wang,Xin Tang,Yu-Hong Wang,Guo-Yi Zhou,Ming-Kai Lin,Jing-Yuan Shen,Jin Yao,Su-Yan Li,Miao-Qin Wu,Hua-Zong Peng,Ming-Ying Lai,Ren-Yi Wu,Yi-Nong Zhang,Yan Li,Xiao-Jun Wu,Ming-Chang Zhang,Su-Ping Guo and Xing-Huai Sun(Int J Ophthalmol 2023;16(1):108-114.DOI:10.18240/ijo.2023.01.16)The authors would like to make the following change to the above article:The name of the second author Yan-Jing Fu should be modified as“Yan-Jiang Fu”.The authors apologize for any inconvenience caused by this error.
文摘Posterior scleral application of a mitomycin C-soaked sponge during trabeculectomy Kun Hu,Yun-He Song,Feng-Bin Lin,Ying-Zhe Zhang,Ling Jin,Meng-Yin Liang,Robert N.Weinreb,Xiu-Lan Zhang(Int J Ophthalmol 2023;16(7):1071-1077,doi:10.18240/ijo.2023.07.11)The authors would like to make the following change to the above article:“MMC was administered as a subconjunctival injection 0.02 mg/mL and 0.1 mL”on page 1073 should be changed to“MMC was administered as a subconjunctival injection 0.2 mg/mL and 0.1 mL”.
文摘Purpose:</span></b><span style="font-family:""><span style="font-family:Verdana;"> Prospective study to evaluate the anti-inflammatory efficacy of isotonic seawater solution on metalloproteinase 9 (MMP-9) levels in the tears of patients with dry eye disease (DED). </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> A total of 50 patients were included, with the following dry eye criteria in both eyes: InflammaDry</span></span><sup><span style="font-family:Verdana;">?</span></sup><span style="font-family:""><span style="font-family:Verdana;"> test initially positive, ocular surface disease index (OSDI) score ≥ 12 and <33, tear film breakup time (TBUT) ≤ 10 seconds, Shirmer I test result ≤ 10 mm/5 minutes, corneal staining ≥ 1. Additionally, all the patients selected corresponded to a dry eye type 2 - 3 severity degree - mild and moderate - Dry Eye Workshop Study (DEWS) classification. The InflammaDry test is used to measure levels of MMP9 at the beginning and the end of the study. All patients were treated exclusively with isotonic seawater solution 5 times a day for 3 weeks. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> The InflammaDry test was positive in 100% of the patients (n = 50) and in 100% (n = 100) of the eyes before treatment. In 14 (28%) patients the test became negative in both eyes, and in 15 (30%) it was negative in one of the eyes. In 43% (n = 43) of the positive eyes, MMP-9 became undetectable in the tear fluid following treatment with isotonic seawater. This change was statistically significant (p < 0.001). </span><b><span style="font-family:Verdana;">Conclusions</span></b><span style="font-family:Verdana;">: The washes with ophthalmic isotonic seawater solution have a significant impact on inflammation of the ocular surface in dry eye disease, with an ability to make MMP-9 levels negative in 43% of cases.
基金Supported by Shaanxi Provincial Key Research and Development Project(No.2018ZDXM-SF-056)Shaanxi Province Social Development and Technology of Research Project(No.2018SF-249)+1 种基金Shaanxi Province Project of Scientific Research Fund for Health(No.2016C004)Xi’an Science and Technology Project No.2017116SF/YX010(5),Xi’an Science and Technology Project No.2017116SF/YX010(6)。
文摘Dear Editor,I am Dr.Xian-Ning Liu,from the Institute of Ophthalmology of Xi’an First Hospital in Xi’an,Shaanxi Province,China.I write to present a case report of corneal ulcer caused by Schizophyllum commune(S.commune).Mycotic keratitis is one of the most severe causes of corneal blindness in developing countries,such as China and India[1-2].
基金Project Supported by National Natural Science Foundation of China.
文摘In order to understand the immune responses to lens protein in patients with congenital cataract, the passive hemagglutination assay for humoral immunity and the leukocyte migration test for cellular immunity to lens protein were performed on 43 patients with congenital cataract and 30 healthy persons served as control.The results showed that there was no significant difference in the incidence of humoral immune responses to lens protein between patients with congenital cataract and the controls (P】0.05), but the incidence of cellular immune responses tolensprotein in patients with congenital cataract was higher than that of the controls (P【0.005).The results of this study suggested that during the development of congenital cataract, lens protein leaked into the aqueous humour and entered the systemic circulation, sensitizing lymphocytes and producing cellular mediated immune responses. Further investigation is neceessary to determine whether there is any relationship between the immune responses to lens protein and the formation of congenital cataract.
文摘9714873 眼外伤的标准化分类法/KuhnF//J Am Acad Ophthalmol.-1995,103(2).-240～243 北医图9714874 上斜眼和后部冲击性骨折:机制和处理/Seiff S R//J Am Acad Ophthal-mol.-1995,103(1).-152～156 北医图9714875 挨打妇女的眼外伤/Beck S R//J Am Acad Ophthalmol.-1995,103(1).-148～151
文摘To the Editor:A 4-month-old girl was brought to the Department of Ophthalmology in the Children’s Hospital,School of Medicine,Zhejiang University,due to"sudden eyeball shaking for a week."The patient was a full-term gravida 2 para 2 infant without any incidence of trauma/surgery;further,the family’s medical history did not reveal any risk factors.Ophthalmological examination revealed bilateral horizontal tremor of the eyes,and both eyes showed light-chasing response.The anterior segment examination was normal.
