大质量恒星强烈的反馈深刻影响其周围的星际介质,并可能触发下一代恒星形成.S187是位于银河系第2象限的大质量恒星形成区,呈现出“扫集-坍缩”的触发式恒星形成模式.基于“银河画卷”巡天^(12)CO/^(13)CO/C^(18)O(J=1-0,下文J=1-0为简...大质量恒星强烈的反馈深刻影响其周围的星际介质,并可能触发下一代恒星形成.S187是位于银河系第2象限的大质量恒星形成区,呈现出“扫集-坍缩”的触发式恒星形成模式.基于“银河画卷”巡天^(12)CO/^(13)CO/C^(18)O(J=1-0,下文J=1-0为简便起见省略)谱线数据,对S187区域分子云的基本性质开展了研究,探索了该区域大质量恒星对分子云的反馈.利用GaussPy+和聚类算法,在该区域证认了32个分子云,并结合Gaia(Global Astrometric Interferometer for Astrophysics)卫星恒星消光数据测量得到其中8个分子云的距离.S187区域由^(13)CO和C^(18)O示踪的相对致密的气体含量相比于银道面第2象限大部分区域的分子云高出1–2个量级.S187区域分子云中证认了243个^(13)CO团块和98个C^(18)O团块,其中有7个^(13)CO团块和5个C^(18)O团块有形成大质量恒星的潜力.研究结果显示,大质量恒星的反馈对其周围分子云的聚集作用明显,为下一代大质量恒星的形成提供了条件.展开更多
Objective:To investigate the expression of RNF187 in hepatocellular carcinoma(HCC)and its relationship with prognosis.Methods:The mRNA and protein expressions in hepatocellular carcinoma and tumor-adjacent tissues of ...Objective:To investigate the expression of RNF187 in hepatocellular carcinoma(HCC)and its relationship with prognosis.Methods:The mRNA and protein expressions in hepatocellular carcinoma and tumor-adjacent tissues of HCC patients were determined by qRT-PCR and Western blot analysis,and RNF187 expressions in HCC were detected by immunohistochemistry.The relationship of RNF187 expression with clinicopathologic factors and prognosis in HCC patients were analyzed.Results:RNF187 expressed highly in HCC tissues compared with the corresponding adjacent liver tissues both in mRNA and protein level,and significantly higher in HCC tissue from patients with intrahepatic metastases or vascular invasion than those in HCC tissue from patients without intrahepatic metastases and vascular invasion(all P<0.05).The 5-year survival rate of the high expression group was lower than that of the low expression group(P<0.05).Cox regression analysis revealed that high RNF187 expression was independent risk factor for postoperative survival(HR=1.313,95%CI=1.128~1.537,P<0.001).Conclusion:High expression of RNF187 in HCC is closely related to tumor prognosis,which may become a new index to evaluate the clinical diagnosis and prognosis of liver cancer.展开更多
文摘大质量恒星强烈的反馈深刻影响其周围的星际介质,并可能触发下一代恒星形成.S187是位于银河系第2象限的大质量恒星形成区,呈现出“扫集-坍缩”的触发式恒星形成模式.基于“银河画卷”巡天^(12)CO/^(13)CO/C^(18)O(J=1-0,下文J=1-0为简便起见省略)谱线数据,对S187区域分子云的基本性质开展了研究,探索了该区域大质量恒星对分子云的反馈.利用GaussPy+和聚类算法,在该区域证认了32个分子云,并结合Gaia(Global Astrometric Interferometer for Astrophysics)卫星恒星消光数据测量得到其中8个分子云的距离.S187区域由^(13)CO和C^(18)O示踪的相对致密的气体含量相比于银道面第2象限大部分区域的分子云高出1–2个量级.S187区域分子云中证认了243个^(13)CO团块和98个C^(18)O团块,其中有7个^(13)CO团块和5个C^(18)O团块有形成大质量恒星的潜力.研究结果显示,大质量恒星的反馈对其周围分子云的聚集作用明显,为下一代大质量恒星的形成提供了条件.
基金Hainan key research and development plan(No.ZDYF2019120)National Natural Science Foundation of China(No.81660489,81260367,81160310)Natural Science Foundation of Hainan Province(No.819QN356)
文摘Objective:To investigate the expression of RNF187 in hepatocellular carcinoma(HCC)and its relationship with prognosis.Methods:The mRNA and protein expressions in hepatocellular carcinoma and tumor-adjacent tissues of HCC patients were determined by qRT-PCR and Western blot analysis,and RNF187 expressions in HCC were detected by immunohistochemistry.The relationship of RNF187 expression with clinicopathologic factors and prognosis in HCC patients were analyzed.Results:RNF187 expressed highly in HCC tissues compared with the corresponding adjacent liver tissues both in mRNA and protein level,and significantly higher in HCC tissue from patients with intrahepatic metastases or vascular invasion than those in HCC tissue from patients without intrahepatic metastases and vascular invasion(all P<0.05).The 5-year survival rate of the high expression group was lower than that of the low expression group(P<0.05).Cox regression analysis revealed that high RNF187 expression was independent risk factor for postoperative survival(HR=1.313,95%CI=1.128~1.537,P<0.001).Conclusion:High expression of RNF187 in HCC is closely related to tumor prognosis,which may become a new index to evaluate the clinical diagnosis and prognosis of liver cancer.
