Research Objective and Overview It is necessary to find effective Chinese materia medica （CMM） for the treatment of refractory hematopathy as commonly used prednisone, androgen and immune suppression agents of tende...Research Objective and Overview It is necessary to find effective Chinese materia medica （CMM） for the treatment of refractory hematopathy as commonly used prednisone, androgen and immune suppression agents of tendemonstrate poor efficacy and serious side effects.展开更多
Objective：To study the relationship between 500 kinds of commonly used Chinese herbal medicine and the classification of their efficacies in Chinese Materia Medica in relation to the common diseases listed in Interna...Objective：To study the relationship between 500 kinds of commonly used Chinese herbal medicine and the classification of their efficacies in Chinese Materia Medica in relation to the common diseases listed in Internal Medicine.Methods：Database retrieval frequency of the quantitative statistical method was adopted.First,the 8 980 kinds of Chinese herbal medicine recorded in Chinese Materia Medica were used as the original search objects,and 4 493 kinds which were cited in more than five articles were picked out and then rechecked for further title citations.Second,as judged based on the Criterion,the numbers of articles which included the medicines in the line of standards were examined.As a result,500 species of Chinese herbal medicine were singled out based on their retrieval frequency and were then used for compilation of the classification statistics according to their efficacy and the common diseases in Internal Medicine.Results：From the classification of Chinese medicines,herbs with wide efficiency and a meek nature had higher frequencies, but those which were not appropriate as decoctions had relatively lower frequencies.However,according to the average frequency,the Chinese herbal medicine for nourishing qi and tonifying blood,at 36 346 times and 34 544 times,respectively,were the most commonly used.Analyzed from the frequency of application of the Chinese medicine in the treatment of common diseases,most of the top 10 kinds of Chinese herbal medicine with the highest frequencies generally coincided with the 500 selected medicines.In addition,the Chinese medicines with clear pharmacological efficiency were easily isolated and purified to be made into injections, although other forms are more commonly used.Conclusion：The results of the research objectively reflected the current applications of Chinese herbal medicine,and could be used as references in teaching,research,clinical applications,and in compiling and increasing the drugs in textbooks and Pharmacopoeia.展开更多
目的:观察中医手法复位联合中药内服外敷治疗闭合性四肢骨折的临床疗效。方法:选取2020年7月至2021年7月高邮市卸甲中心卫生院治疗的闭合性四肢骨折患者92例,按照随机数字表法分成常规组和试验组,各46例。常规组给予中医手法复位治疗,...目的:观察中医手法复位联合中药内服外敷治疗闭合性四肢骨折的临床疗效。方法:选取2020年7月至2021年7月高邮市卸甲中心卫生院治疗的闭合性四肢骨折患者92例,按照随机数字表法分成常规组和试验组,各46例。常规组给予中医手法复位治疗,试验组给予中医手法复位联合中药内服外敷治疗。观察两组患者治疗前后中医症状体征评分、血沉、红细胞压积、全血比黏度、血浆比黏度、骨形态发生蛋白-2(bone morphogenetic protein-2,BMP-2)、骨γ-羧基谷氨酸蛋白(boneγ-bone gla protein,BGP)、Ⅰ型前胶原羧基端肽(carboxyterminal propeptide of type I procollagen,PICP)变化情况,并统计两组患者骨折愈合时间、不良反应发生率及临床疗效。结果:试验组治疗后中医症状体征评低于常规组,差异有统计学意义(P<0.05);试验组治疗后血沉、红细胞压积、全血比黏度、血浆比黏度均低于常规组,差异有统计学意义(P<0.05);试验组治疗后BMP-2、BGP、PICP水平均高于常规组,差异有统计学意义(P<0.05);试验组治疗后骨折愈合时间、不良反应发生率低于常规组,差异有统计学意义(P<0.05);试验组有效率为95.65%,常规组有效率为84.78%,试验组有效率高于常规组,差异有统计学意义(P<0.05)。结论:中医手法复位联合中药内服外敷治疗闭合性四肢骨折,能缓解患者疼痛肿胀,加速新骨形成,促进骨折早日愈合。展开更多
基金Supported by Australia-China Links Program sponsored by IDP Education Australia (NoⅡ-8)the National Natural Science Foundation of China (No 30070933)+1 种基金the Natural Science Foundation of Zhejiang Province as the key project (No DZ007)State Administration of TCM of China (No 972025)
文摘Research Objective and Overview It is necessary to find effective Chinese materia medica （CMM） for the treatment of refractory hematopathy as commonly used prednisone, androgen and immune suppression agents of tendemonstrate poor efficacy and serious side effects.
基金Supported by Natural Science Foundation of Henan Province (No.0611041900)
文摘Objective：To study the relationship between 500 kinds of commonly used Chinese herbal medicine and the classification of their efficacies in Chinese Materia Medica in relation to the common diseases listed in Internal Medicine.Methods：Database retrieval frequency of the quantitative statistical method was adopted.First,the 8 980 kinds of Chinese herbal medicine recorded in Chinese Materia Medica were used as the original search objects,and 4 493 kinds which were cited in more than five articles were picked out and then rechecked for further title citations.Second,as judged based on the Criterion,the numbers of articles which included the medicines in the line of standards were examined.As a result,500 species of Chinese herbal medicine were singled out based on their retrieval frequency and were then used for compilation of the classification statistics according to their efficacy and the common diseases in Internal Medicine.Results：From the classification of Chinese medicines,herbs with wide efficiency and a meek nature had higher frequencies, but those which were not appropriate as decoctions had relatively lower frequencies.However,according to the average frequency,the Chinese herbal medicine for nourishing qi and tonifying blood,at 36 346 times and 34 544 times,respectively,were the most commonly used.Analyzed from the frequency of application of the Chinese medicine in the treatment of common diseases,most of the top 10 kinds of Chinese herbal medicine with the highest frequencies generally coincided with the 500 selected medicines.In addition,the Chinese medicines with clear pharmacological efficiency were easily isolated and purified to be made into injections, although other forms are more commonly used.Conclusion：The results of the research objectively reflected the current applications of Chinese herbal medicine,and could be used as references in teaching,research,clinical applications,and in compiling and increasing the drugs in textbooks and Pharmacopoeia.
文摘目的:观察中医手法复位联合中药内服外敷治疗闭合性四肢骨折的临床疗效。方法:选取2020年7月至2021年7月高邮市卸甲中心卫生院治疗的闭合性四肢骨折患者92例,按照随机数字表法分成常规组和试验组,各46例。常规组给予中医手法复位治疗,试验组给予中医手法复位联合中药内服外敷治疗。观察两组患者治疗前后中医症状体征评分、血沉、红细胞压积、全血比黏度、血浆比黏度、骨形态发生蛋白-2(bone morphogenetic protein-2,BMP-2)、骨γ-羧基谷氨酸蛋白(boneγ-bone gla protein,BGP)、Ⅰ型前胶原羧基端肽(carboxyterminal propeptide of type I procollagen,PICP)变化情况,并统计两组患者骨折愈合时间、不良反应发生率及临床疗效。结果:试验组治疗后中医症状体征评低于常规组,差异有统计学意义(P<0.05);试验组治疗后血沉、红细胞压积、全血比黏度、血浆比黏度均低于常规组,差异有统计学意义(P<0.05);试验组治疗后BMP-2、BGP、PICP水平均高于常规组,差异有统计学意义(P<0.05);试验组治疗后骨折愈合时间、不良反应发生率低于常规组,差异有统计学意义(P<0.05);试验组有效率为95.65%,常规组有效率为84.78%,试验组有效率高于常规组,差异有统计学意义(P<0.05)。结论:中医手法复位联合中药内服外敷治疗闭合性四肢骨折,能缓解患者疼痛肿胀,加速新骨形成,促进骨折早日愈合。
