BACKGROUND The evidence on preferences for oral-vs blood-based human immunodeficiency virus self-testing(HIVST)has been heterogenous and inconclusive.In addition,most evaluations have relied on hypothetical or stated ...BACKGROUND The evidence on preferences for oral-vs blood-based human immunodeficiency virus self-testing(HIVST)has been heterogenous and inconclusive.In addition,most evaluations have relied on hypothetical or stated use cases using discreet choice experiments rather than actual preferences among experienced users,which are more objective and critical for the understanding of product uptake.Direct head-to-head comparison of consumer preferences for oral-versus bloodbased HIVST is lacking.AIM To examine the existing literature on preferences for oral-vs blood-based HIVST,determine the factors that impact these preferences,and assess the potential implications for HIVST programs.METHODS Databases such as PubMed,Medline,Google Scholar,and Web of Science were searched for articles published between January 2011 to October 2022.Articles must address preferences for oral-vs blood-based HIVST.The study used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist to ensure the quality of the study.RESULTS The initial search revealed 2424 records,of which 8 studies were finally included in the scoping review.Pooled preference for blood-based HIVST was 48.8%(9%-78.6%),whereas pooled preference for oral HIVST was 59.8%(34.2%-91%)across all studies.However,for male-specific studies,the preference for blood-based HIVST(58%-65.6%)was higher than that for oral(34.2%-41%).The four studies that reported a higher preference for blood-based HIVST were in men.Participants considered blood-based HIVST to be more accurate and rapid,while those with a higher preference for oral HIVST did so because these were considered non-invasive and easy to use.CONCLUSION Consistently in the literature,men preferred blood-based HIVST over oral HIVST due to higher risk perception and desire for a test that provides higher accuracy coupled with rapidity,autonomy,privacy,and confidentiality,whereas those with a higher preference for oral HIVST did so because these were considered non-invasive and easy to use.Misinformation and distrust need to be addressed through promotional messaging to maximize the diversity of this new biomedical technology.展开更多
目的探索上海市男男同性性行为人群(men who have sex with men, MSM)对人类免疫缺陷病毒(human immunodeficiency virus, HIV)抗体唾液快速检测试剂自检(口腔自检)方式检测HIV的使用情况和影响因素。方法 2019年1月—2020年12月,社区组...目的探索上海市男男同性性行为人群(men who have sex with men, MSM)对人类免疫缺陷病毒(human immunodeficiency virus, HIV)抗体唾液快速检测试剂自检(口腔自检)方式检测HIV的使用情况和影响因素。方法 2019年1月—2020年12月,社区组织"上海心生"和上海市静安区疾病预防控制中心自愿咨询检测(voluntary counseling testing, VCT)门诊,共同招募MSM为研究对象。采用自行设计的调查问卷,在知情同意前提下,以问卷星网站在线调查的方式开展调查,收集其人口学特征、性行为特征、对口腔自检的认知和使用情况等信息。结果共2 589名MSM纳入研究,使用过口腔自检1 427例(55.12%)。多因素logistic回归分析显示,既往使用口腔自检情况在年龄<50岁(OR=1.87,95%CI:1.18~2.96),最近6个月男性性伴数≥2个(OR=1.33,95%CI:1.12~1.58),最近1年在检测点做过HIV检测(OR=1.92,95%CI:1.53~2.41),朋友/性伴中有人使用口腔自检(OR=8.49, 95%CI:5.78~12.48)或者不清楚朋友/性伴中是否使用过口腔自检(OR=1.54, 95%CI:1.04~2.48)差异有统计学意义(P<0.05)。口腔自检试剂价格从60元下降到40元、20元时弹性系数分别为2.42、1.47。结论上海市MSM口腔自检使用率相对较低,年龄、对高危因素的感知程度以及朋友/性伴推荐是影响HIV口腔自检使用的重要因素。降低试剂价格可能促进口腔自检的使用。展开更多
文摘BACKGROUND The evidence on preferences for oral-vs blood-based human immunodeficiency virus self-testing(HIVST)has been heterogenous and inconclusive.In addition,most evaluations have relied on hypothetical or stated use cases using discreet choice experiments rather than actual preferences among experienced users,which are more objective and critical for the understanding of product uptake.Direct head-to-head comparison of consumer preferences for oral-versus bloodbased HIVST is lacking.AIM To examine the existing literature on preferences for oral-vs blood-based HIVST,determine the factors that impact these preferences,and assess the potential implications for HIVST programs.METHODS Databases such as PubMed,Medline,Google Scholar,and Web of Science were searched for articles published between January 2011 to October 2022.Articles must address preferences for oral-vs blood-based HIVST.The study used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist to ensure the quality of the study.RESULTS The initial search revealed 2424 records,of which 8 studies were finally included in the scoping review.Pooled preference for blood-based HIVST was 48.8%(9%-78.6%),whereas pooled preference for oral HIVST was 59.8%(34.2%-91%)across all studies.However,for male-specific studies,the preference for blood-based HIVST(58%-65.6%)was higher than that for oral(34.2%-41%).The four studies that reported a higher preference for blood-based HIVST were in men.Participants considered blood-based HIVST to be more accurate and rapid,while those with a higher preference for oral HIVST did so because these were considered non-invasive and easy to use.CONCLUSION Consistently in the literature,men preferred blood-based HIVST over oral HIVST due to higher risk perception and desire for a test that provides higher accuracy coupled with rapidity,autonomy,privacy,and confidentiality,whereas those with a higher preference for oral HIVST did so because these were considered non-invasive and easy to use.Misinformation and distrust need to be addressed through promotional messaging to maximize the diversity of this new biomedical technology.
文摘目的探索上海市男男同性性行为人群(men who have sex with men, MSM)对人类免疫缺陷病毒(human immunodeficiency virus, HIV)抗体唾液快速检测试剂自检(口腔自检)方式检测HIV的使用情况和影响因素。方法 2019年1月—2020年12月,社区组织"上海心生"和上海市静安区疾病预防控制中心自愿咨询检测(voluntary counseling testing, VCT)门诊,共同招募MSM为研究对象。采用自行设计的调查问卷,在知情同意前提下,以问卷星网站在线调查的方式开展调查,收集其人口学特征、性行为特征、对口腔自检的认知和使用情况等信息。结果共2 589名MSM纳入研究,使用过口腔自检1 427例(55.12%)。多因素logistic回归分析显示,既往使用口腔自检情况在年龄<50岁(OR=1.87,95%CI:1.18~2.96),最近6个月男性性伴数≥2个(OR=1.33,95%CI:1.12~1.58),最近1年在检测点做过HIV检测(OR=1.92,95%CI:1.53~2.41),朋友/性伴中有人使用口腔自检(OR=8.49, 95%CI:5.78~12.48)或者不清楚朋友/性伴中是否使用过口腔自检(OR=1.54, 95%CI:1.04~2.48)差异有统计学意义(P<0.05)。口腔自检试剂价格从60元下降到40元、20元时弹性系数分别为2.42、1.47。结论上海市MSM口腔自检使用率相对较低,年龄、对高危因素的感知程度以及朋友/性伴推荐是影响HIV口腔自检使用的重要因素。降低试剂价格可能促进口腔自检的使用。
