AIM: To quantitatively evaluate the impact of smoking on tooth loss.METHODS: We performed a Pub Med search to identify published articles that investigated the risk of tooth loss by smoking, from which RRs and their v...AIM: To quantitatively evaluate the impact of smoking on tooth loss.METHODS: We performed a Pub Med search to identify published articles that investigated the risk of tooth loss by smoking, from which RRs and their variance with characteristics of each study were extracted. The random-effects models were used to derive a pooled effect across studies. Potential sources of heterogeneity on the characteristics of the study and their influence on the pooled effect size were investigated using metaregression models. RESULTS: We identified 24 studies containing a total of 95973 participants for analysis. The pooled RR of ever-smokers compared with never- smokers was 1.73(95%CI: 1.60-1.86, P < 0.001). In meta-regression analysis, only the mean age of participants alone was identified as a statistically significant source of heterogeneity. The effect of smoking on tooth loss was stronger when the mean age of study participants was higher, indicating possible enhancement of tooth loss due to aging by smoking. RR was significantly lower in former smokers(1.49, 95%CI: 1.32-1.69, P < 0.001) than in current smokers(2.10, 95%CI: 1.87-2.35, P < 0.001), indicating the substantial benefit of smoking cessation for reducing the risk of tooth loss.CONCLUSION: Smoking is an independent risk factor for tooth loss regardless of many other confounders. Smoking cessation may attenuate this effect.展开更多
目的探讨癌症长期生存者生命质量与牙齿缺失及口腔卫生状况之间的关系。方法2013年4—7月在上海市采用整群抽样法对5623名癌症长期生存者进行问卷调查,调查内容包括社会人口学情况、肿瘤的诊断和治疗情况、口腔健康状况(牙齿缺失数、刷...目的探讨癌症长期生存者生命质量与牙齿缺失及口腔卫生状况之间的关系。方法2013年4—7月在上海市采用整群抽样法对5623名癌症长期生存者进行问卷调查,调查内容包括社会人口学情况、肿瘤的诊断和治疗情况、口腔健康状况(牙齿缺失数、刷牙频次、牙齿检查)等,采用癌症治疗功能评价系统量表体系中的共性模块(Functional Assessment of Cancer Therapy-General,FACT-G)评估癌症生存者的生命质量。采用多重线性回归模型评估FACT-G各维度生命质量得分在不同牙齿缺失数、刷牙频次、牙齿检查上的均数差(mean difference,MD)和95%可信区间(95%CI)。结果17.5%的癌症长期生存者牙齿缺失超过10颗,57.05%的癌症长期生存者能坚持每天至少刷牙2次,仅7.7%的癌症长期生存者坚持至少每年进行1次牙齿检查。FACT-G各维度得分和量表总分随着牙齿缺失数量的增加而减少(P_(trend)均<0.05)。刷牙≥2次/天的癌症长期生存者FACT-G量表总分均高于刷牙≤1次/天的癌症长期生存者。每年至少进行1次牙齿检查的癌症长期生存者的社会状况、功能状况维度得分和FACT-G量表总分均高于不能每年进行牙齿检查的癌症长期生存者。结论牙齿缺失数、刷牙频次和牙齿检查与上海市癌症长期生存者的整体生命质量存在关联,良好的口腔健康状况和科学的口腔健康行为可能有助于改善癌症生存者的生命质量。展开更多
基金Supported by Grant-in-Aid for the Third Term Comprehensive 10-year Strategy for Cancer Control,No.H20-3rd-002Grant-in-Aid for Cancer Research,Grant No.13-21-13-1 from the Japanese Ministry of Health,Labor and Welfare
文摘AIM: To quantitatively evaluate the impact of smoking on tooth loss.METHODS: We performed a Pub Med search to identify published articles that investigated the risk of tooth loss by smoking, from which RRs and their variance with characteristics of each study were extracted. The random-effects models were used to derive a pooled effect across studies. Potential sources of heterogeneity on the characteristics of the study and their influence on the pooled effect size were investigated using metaregression models. RESULTS: We identified 24 studies containing a total of 95973 participants for analysis. The pooled RR of ever-smokers compared with never- smokers was 1.73(95%CI: 1.60-1.86, P < 0.001). In meta-regression analysis, only the mean age of participants alone was identified as a statistically significant source of heterogeneity. The effect of smoking on tooth loss was stronger when the mean age of study participants was higher, indicating possible enhancement of tooth loss due to aging by smoking. RR was significantly lower in former smokers(1.49, 95%CI: 1.32-1.69, P < 0.001) than in current smokers(2.10, 95%CI: 1.87-2.35, P < 0.001), indicating the substantial benefit of smoking cessation for reducing the risk of tooth loss.CONCLUSION: Smoking is an independent risk factor for tooth loss regardless of many other confounders. Smoking cessation may attenuate this effect.
文摘目的探讨癌症长期生存者生命质量与牙齿缺失及口腔卫生状况之间的关系。方法2013年4—7月在上海市采用整群抽样法对5623名癌症长期生存者进行问卷调查,调查内容包括社会人口学情况、肿瘤的诊断和治疗情况、口腔健康状况(牙齿缺失数、刷牙频次、牙齿检查)等,采用癌症治疗功能评价系统量表体系中的共性模块(Functional Assessment of Cancer Therapy-General,FACT-G)评估癌症生存者的生命质量。采用多重线性回归模型评估FACT-G各维度生命质量得分在不同牙齿缺失数、刷牙频次、牙齿检查上的均数差(mean difference,MD)和95%可信区间(95%CI)。结果17.5%的癌症长期生存者牙齿缺失超过10颗,57.05%的癌症长期生存者能坚持每天至少刷牙2次,仅7.7%的癌症长期生存者坚持至少每年进行1次牙齿检查。FACT-G各维度得分和量表总分随着牙齿缺失数量的增加而减少(P_(trend)均<0.05)。刷牙≥2次/天的癌症长期生存者FACT-G量表总分均高于刷牙≤1次/天的癌症长期生存者。每年至少进行1次牙齿检查的癌症长期生存者的社会状况、功能状况维度得分和FACT-G量表总分均高于不能每年进行牙齿检查的癌症长期生存者。结论牙齿缺失数、刷牙频次和牙齿检查与上海市癌症长期生存者的整体生命质量存在关联,良好的口腔健康状况和科学的口腔健康行为可能有助于改善癌症生存者的生命质量。