Teaching of Organic Chemistry of Cultivating Applied Pharmaceutical Talents

In order to effectively cultivate applied pharmaceutical talents,aiming at the current teaching situation of organic chemistry,the basic course of pharmaceutical specialty,including the problems of curriculum setting,experimental teaching,and the integration of classroom and professional knowledge,it is proposed to overcome the problem of curriculum setting by combining"online+offline"in teaching.It should overcome the problems in experimental teaching with the help of virtual simulation platform.By cultivating students organic chemistry thinking and paying attention to the integration of subject and professional knowledge,students recognition of organic chemistry course can be improved,and the quality of training can be improved.

外国留学生高职“Organic Chemistry”全英文教学实践探讨

在高等职业教育国际化趋势下,随着留学生教育的开展,针对化工类专业留学生的“Organic Chemistry”(“有机化学”)课程全英文教学,从师资队伍建设、讲义教材建设、教学内容安排、教学模式探索、学业成绩考核等方面来做探讨,旨在努力提升面向留学生的专业课程教学质量。

David R.Klein的《Organic Chemistry》内容介绍

翻译了David R.Klein教授在2012年编著的《Organic Chemistry》的主要内容,全书27章,这本书仍然依照传统官能团分类编排,但将重点放在机理的介绍上。第六章介绍了化学反应和机制,第十二章介绍了合成的知识。正文之后给出各章所涉及的概念和词汇小结、关键术语,有助于教师的教学总结和学生的自修性复习。正文中间的习题和各章正文之后的三种类型习题进一步考察对知识的掌握。期望能为国内大学有机化学教材内容的编排提供一些参考。

Difference in Number of Electrons in Inner Shells of Charged or Uncharged Elements in Organic and Inorganic Chemistry: Compatibility with the Even-Odd Rule

The recently introduced even-odd rule has been shown to successfully represent chemical structures of ions and molecules. While comparing available drawings in the scientific literature with the list of compounds predicted by the even-odd rule, it became however obvious that existing compounds are fewer than expected. Several predicted compounds involving many covalent bonds have apparently never been experimentally observed. Neutral oxygen for instance is expected to have 6 valence electrons, whereas oxygen can only build a maximum of two bonds, as in water. This specificity is observed for elements in the top-right corner of the periodic table. For compounds to contain only single covalent bonds, and thus follow the even-odd rule, further explanations are necessary. The present paper proposes that those specific elements experience a transfer of electrons from the valence shell into the inner shell, making them unavailable for further bonding. These elements will be described as organic, hereby providing a clear and hopefully unifying definition of the term. In opposition, inorganic elements have a constant inner shell no matter their electrical state or the number of bonds they maintain. More than 70 compounds involving 11 elements of the main group are studied, revealing a progression from fully inorganic elements at the left of the periodic table to fully organic elements. The transition between inorganic or organic elements is made of few elements that take an organic form when negatively charged;they are labelled semi-organic. The article concludes that the fully organic elements of the main group are Oxygen and Fluorine, whereas semi-organic elements are more numerous: C, N, S, Cl, Se, Br and I. Thus, the even-odd rule becomes fully compatible with scientific knowledge of compounds in liquid or gaseous phase.

A Specific Periodic Table for Chemistry of Organic, Semi-Organic and Inorganic Elements: Compatibility with the Even-Odd Rule,the Number of Electrons and the Isoelectronicity Rule

Following the introduction of the new even-odd and isoelectronic rules and definitions affecting the understanding of electronic structure and bonds, the author has thought necessary to summarize understandings in the form of a table. The classical periodic table, a simple tool used by generations of physicists, is here extended to become a useful tool aimed specifically at chemists. In chemistry, position and number of covalent bonds of each atom are needed, as well as the exact location of charges. The table gives the number of possible bonds for each element and reveals how it is affected by charges. Additionally, the specific table indicates for each atom its isoelectronic elements and highlights the distinction between organic and inorganic elements. Discussion is led on the first two rows of the table by successfully comparing its statement with more than 50 well-known liquid and gaseous compounds.

Effects of water chemistry and concentrations of dissolved organic matter on its fluorescence characteristics and molecular conformation

Previous studies showed that water chemistry and concentrations of dissolved organic matter (DOM) could affect its molecular conformation and binding characteristics with hydrophobic organic contaminants (HOCs). However, the conformational change of DOM resultant from water chemistry and concentrations of DOM was not extensively investigated; therefore, the contradictory reports regarding the binding property with HOCs were available in literature. In this study, the effects of ionic strength, pH and DOM concentrations on the fluorescence properties of two humic acids (HA), namely Fluka HA and Amherst HA, were investigated by three-dimensional excitation-emission matrix fluorescence spectroscopy (3DEEM) and steady-state fluorescence polarization (FP) techniques. The results not only corroborated previous observations obtained by other investigators, but revealed some new information about the fluorescence properties and molecular conformation of the humic acids under different water chemistry and DOM concentration conditions, which could shed light on its binding mechanisms and binding properties with HOCs.

Review of general, organic, and biological chemistry, second edition

Overall, General, Organic, and Biological Chemistry is a very useful text to support a twosemester undergraduate course series in chemistry for health sciences students. Its strengths are the use of the P.A.V.E. way to student learning applications. It is very obvious that the author has the background and the preparation of the student taking the course(s) in mind when she was writing the textbook.

Proximity of Problem-Based Learning(ABP)Methodology to Experimental Teaching in Organic Chemistry.IMINE Synthesis

Different imines were prepared.The reaction was carried out using different conditions,with aromatic aldehydes,aniline and with different energy sources.Yield,purity and experimental fusion point were calculated in each case,and they were compared to the ones found in literature.The importance of structural effects of aldehyde reacting with aniline was established as well as reaction conditions.The efficacy of the reaction can not be predicted,since each aldehyde has a different structure and therefore reacts differently.The main objective of this project is academic.A methodology to carry out a structured research(it is one of the levels of problem-based learning(ABP)),was implemented.Students work in pairs using Combinatorial Chemistry,and each pair does a different exercise on the same theoretical objective.Results from every team are discussed in a seminary where conclusions regarding which was the most efficient reaction are reached.

Ionic covalent organic frameworks with tailored anionic redox chemistry and selective ion transport for high-performance Na-ion cathodes

Employing cathode materials with multiple redox couples and electrolytes with efficient cation transport kinetics are two effective approaches to improving the electrochemical performance of batteries.In this work,for the first time,we present a design strategy of simultaneously realizing reversible cationic and anionic redox chemistries as well as selective anion/cation transport in the viologen-based COFs(BAVCOF:X,coordinated anions of X=Cl^(-),Br^(-),I^(-),and ClO_(4)^(-))for high-performance Na-ion cathodes.Besides the cationic redox of viologen segments,the different redox activities of anions effectively tune the total capacities of the COFs.Meanwhile,electrochemical analysis and ab-initial molecular dynamics(AIMD)calculation illustrate that the anion/cation transport kinetics of electrolytes caged in the COFs'channels can be selectively tuned by the coordinated anions.As a result,combining high-potential Br-/Br_(2)redox couple,cationic redox of viologen segments,and enhanced Na+transport kinetics,the BAV-COF:Brdemonstrates stable performance with energy densities of 358.7 and 145.2 Wh kg^(-1)at power densities of 116.5 and 2124.1 W kg^(-1),respectively.This study offers new insight into the fabrication of organic cathodes with anionic redox and the advantages of COFs electrode materials in anion/cation transport selectivity for energy storage applications.

Simulating the Impacts of Marine Organic Emissions on Global Atmospheric Chemistry and Aerosols Using an Online-Coupled Meteorology and Chemistry Model

To realistically simulate the impacts of marine isoprene and primary organic aerosols (POA) on atmospheric chemistry, a unified model framework with online emissions, comprehensive treatment of gas-phase chemistry, and advanced aerosol microphysics is required. In this work, the global-through-urban WRF/Chem model (GU-WRF/Chem) implemented with the online emissions of marine isoprene and size-resolved marine POA is applied to examine such impacts. The net effect of these emissions was increased surface concentrations of isoprene and organic aerosols and decreased surfaced concentrations of hydroxyl radical and ozone over most marine regions. With the inclusion of these emissions, GU-WRF/Chem better predicted the surface concentrations of isoprene and organic aerosols and the aerosol number size distribution when compared to measurements in clean marine conditions.

University Organic Chemistry Education Technological innovation

the paper discusses the advantage and disadvantage of organic chemistry teaching mode of multimedia auxiliary university compared with traditional teaching mode. And combined with the author＇ s teaching practice the paper sums up that the multimedia technology shall be used as the auxiliary method of traditional teaching to optimize classroom teaching, improve the classroom efficiency and reflect the true value of the multimedia auxiliary teaching.

Sodium-Coordinated Polymeric Phthalocyanines as Stable High-Capacity Organic Anodes for Sodium-Ion Batteries

Sodium-ion batteries(SIBs)have attracted considerable interest as an alternative to lithium-ion batteries owing to their similar electrochemical performance and superior long-term cycle stability.Organic materials are regarded as promising anode materials for constructing SIBs with high capacity and good retention.However,utilization of organic materials is rather limited by their low energy density and poor stability at high current densities.To overcome these limitations,we utilized a novel polymeric disodium phthalocyanines(pNaPc)as SIB anodes to provide stable coordination sites for Na ions as well as to enhance the stability at high current density.By varying the linker type during a one-pot cyclization and polymerization process,two pNaPc anodes with O-(O-pNaPc)and S-linkers(S-pNaPc)were prepared,and their structural and electrochemical properties were investigated.The O-pNaPc binds Na ions with a lower binding energy compared with S-pNaPc,which leads to more facile Na-ion coordination/dissociation when engaged as SIB anode.The use of O-pNaPc significantly improves the redox kinetics and cycle stability and allows the fabrication of a full cell against Na_(3)V_(2)(PO_(4))_(2)F_(3)/C cathode,which demonstrates its practical application with high energy density(288 Wh kg^(-1))and high power density(149 W kg^(-1)).

Teaching Effectiveness of Integrating Task-based Approach into Inorganic and Analytical Chemistry Course

From the perspective of students,the effectiveness of task-based approach in In-organic and Analytical Chemistry course were summarized.The strength and weak points of TBA were analyzed,and the specific suggestions for obtaining better effect were put forward.The result showed a satisfactory achievement and unexpected result in showing the effectiveness of this teaching model.Not only could this TBA enhance student's overall knowledge of discipline but also cultivate students' multi-dimensional competence:competence in searching literatures, communication and management,autonomous,co-operative and reflective learning,and competence in analyzing and problem-solving,as well as improving their language expression ability,and skills in using multi-media and internet technology into their academic course learning and research.The implication of this research on the classroom teaching practice will shed light on the future teaching reform of other courses in China.

TO EXPLORE THE MYSTERIES OF LIFE: A TALK ON ORGANIC CHEMISTRY AT THE TURN OF THE CENTURY

After a disciplinary upsurge, organic chemistry is about to embark on an epoch-making transition at the turn of the century. At present when the discipline is once again making its way into life sciences, this article gives a running commmentary on its current state and some developmental trends making a debut in this new research orientation. Finally, several ideas are aired to the community of Chinese chemists, advising them on how to welcome the historic transition.

有机化学实验课教学质量提升的探索与实践

本文介绍了有机化学实验教学过程中存在的一些问题,并从强化学生预习效果、加强教师技能培训、重视集体备课、强化实验过程的教师指导、增加课后的评价反思等方面介绍了我校提高有机化学实验教学质量的探索和实践。

农科特色有机化学课程的教学探索与实践

立足高等农林教育,从教学案例、教学方法、教师团队建设等方面对有机化学课程教学进行了探索和实践。教学实践表明,激发了学生的学习兴趣,拓展了学生的视野,助力学生领略了有机化学研究前沿(尤其是与农科交叉融合应用前沿)魅力,培养了学生的文化素养、职业素养和科学素养,塑造了学生“知农爱农”的情怀,厚植了学生的家国情怀;实现了知识传授、能力培养与价值引领的同向同行和交相辉映,有效解决了公共基础课与专业教育需求不能完全匹配的问题,充分发挥了课程在农科人才培养中的作用。

面向林学专业群的有机化学实验教学内容改革实践与探索

作为高等学校公共基础课,有机化学实验因教学资源不足,普遍存在教学内容千篇一律、与专业特色契合度低等问题,导致学生学习动力不足。本文结合西南林业大学实际,尝试将具有植物资源培养、开发、利用的相关专业组成林学专业群,并针对该专业群,构建了以天然产物提取、分离、纯化、鉴定为主线的有机化学实验教学体系。学生期末考试表现及问卷调查结果表明,新教学体系对提升学生学习兴趣、改善学生培养质量具有显著的推进作用,同时也为在教学体系中融入农林特质提供了思路。

新工科背景下有机化学课程教学实践与探索

在新工科背景下,化学专业必修的基础课程有机化学通过进行前沿介绍、难点讲解、结合专业、融入科研和知识拓展等新形式的教学理念,让学生对有机化学产生浓厚的学习兴趣,锻炼学生的自主学习能力,提高有机化学的教学效果。与此同时,在课堂上结合前景回顾、新课导入、知识讲解、师生互动、问题交流、分组讨论等多种授课新模式,利用多元化的学习方法,配合作业讲评、习题训练、在线解答、组织讨论、定期复习等形式的课后巩固,有效提升了教学效果。

创新创业人才培养视域下中医药院校无机化学双语教学的理念、价值和路径

随着经济全球化和国际交流的加深,培养具备跨文化交流和创新创业能力的中医药人才已成为中医药院校教育改革的核心任务之一。该文以创新创业人才培养视域为切入点,探讨了中医药院校在无机化学课程中引入双语教学的理念、价值和路径,并提出了相关策略和建议,以期为“高品质、国际化、创新型”中药专业人才的培养提供理论和实践参考。