Around 450 cases of acute severe hepatitis of unknown origin in children have been reported in 21 countries and region globally since April 2022,which has exceeded the past annual incidences of related regions,and has...Around 450 cases of acute severe hepatitis of unknown origin in children have been reported in 21 countries and region globally since April 2022,which has exceeded the past annual incidences of related regions,and has aroused wide concern.Affected patients were predominantly children under 16years of age,presented with symptoms of acute hepatitis with markedly elevated liver enzymes,and had been ruled out of common viral infections such as hepatitis A,B,C,D,and E.Similar cases have not been reported in China yet.However,considering that the severe acute hepatitis has involved worldwide areas,still with unknown origin,and incidences of severity is relatively high,we formulated this recommendation to standardize diagnosis and treatment of acute severe hepatitis of unknown origin in Peking Union Medical College Hospital,to get fully prepared to the possible public health events.展开更多
目的左冠状动脉起源于肺动脉(anomalous origin of the left coronary artery from the pulmomaryar-tery,ALCAPA)是临床上一种少见的先天性冠状动脉异常性疾病,目前国内报道的资料不多。该研究对其临床特点与治疗进行探讨。方法对10例...目的左冠状动脉起源于肺动脉(anomalous origin of the left coronary artery from the pulmomaryar-tery,ALCAPA)是临床上一种少见的先天性冠状动脉异常性疾病,目前国内报道的资料不多。该研究对其临床特点与治疗进行探讨。方法对10例诊断为左冠状动脉起源于肺动脉患儿的临床表现、心电图特征、心脏超声、心导管资料、手术治疗及转归进行分析。结果患儿都有不同程度的多汗、烦躁、气促、拒食等心绞痛及心功能不全的表现;心电图、彩色超声心动图及心导管检查有较特征性的改变;4例患儿行肺动脉内隧道术,4例行直接左冠状动脉移植术,2例行左冠状动脉重建术。术后8例症状改善,2例死亡。结论掌握ALCAPA的病变特点和相关的诊断线索,辅以彩色超声心动图和心导管检查,可提高ALCAPA的检出率,并早期手术治疗。展开更多
左冠状动脉异常起源于肺动脉(anomalous origin of the left coronary artery from the pulmonary artery,ALCAPA)是由于在胚胎发育的过程中左冠状动脉丛未与主动脉芽连接,而与肺动脉芽异常连接导致的冠状动脉一支或主要分支或两支起...左冠状动脉异常起源于肺动脉(anomalous origin of the left coronary artery from the pulmonary artery,ALCAPA)是由于在胚胎发育的过程中左冠状动脉丛未与主动脉芽连接,而与肺动脉芽异常连接导致的冠状动脉一支或主要分支或两支起源于肺动脉的先天性畸形,发病率为1/30万,占先天性心脏病的0.26%-0.50%。展开更多
文摘Around 450 cases of acute severe hepatitis of unknown origin in children have been reported in 21 countries and region globally since April 2022,which has exceeded the past annual incidences of related regions,and has aroused wide concern.Affected patients were predominantly children under 16years of age,presented with symptoms of acute hepatitis with markedly elevated liver enzymes,and had been ruled out of common viral infections such as hepatitis A,B,C,D,and E.Similar cases have not been reported in China yet.However,considering that the severe acute hepatitis has involved worldwide areas,still with unknown origin,and incidences of severity is relatively high,we formulated this recommendation to standardize diagnosis and treatment of acute severe hepatitis of unknown origin in Peking Union Medical College Hospital,to get fully prepared to the possible public health events.
文摘目的左冠状动脉起源于肺动脉(anomalous origin of the left coronary artery from the pulmomaryar-tery,ALCAPA)是临床上一种少见的先天性冠状动脉异常性疾病,目前国内报道的资料不多。该研究对其临床特点与治疗进行探讨。方法对10例诊断为左冠状动脉起源于肺动脉患儿的临床表现、心电图特征、心脏超声、心导管资料、手术治疗及转归进行分析。结果患儿都有不同程度的多汗、烦躁、气促、拒食等心绞痛及心功能不全的表现;心电图、彩色超声心动图及心导管检查有较特征性的改变;4例患儿行肺动脉内隧道术,4例行直接左冠状动脉移植术,2例行左冠状动脉重建术。术后8例症状改善,2例死亡。结论掌握ALCAPA的病变特点和相关的诊断线索,辅以彩色超声心动图和心导管检查,可提高ALCAPA的检出率,并早期手术治疗。
文摘左冠状动脉异常起源于肺动脉(anomalous origin of the left coronary artery from the pulmonary artery,ALCAPA)是由于在胚胎发育的过程中左冠状动脉丛未与主动脉芽连接,而与肺动脉芽异常连接导致的冠状动脉一支或主要分支或两支起源于肺动脉的先天性畸形,发病率为1/30万,占先天性心脏病的0.26%-0.50%。