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Root Resorption of Central Incisor by Impacted Canine in Unusual Transposition: Orthodontics and Implant Rehabilitation: 3-Year Follow-Up
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作者 Miguel Ángel Garcés-Villalá Silvia Lorena Sticca-Peralta +1 位作者 Sergio David Rico-Jordán José Luis Calvo-Guirado 《Journal of Biosciences and Medicines》 2021年第10期55-64,共10页
This case presents an unusual transposition of an impacted canine on the central incisor that provides a multidisciplinary approach to its resolution. The patient comes to the consultation for mobility of the central ... This case presents an unusual transposition of an impacted canine on the central incisor that provides a multidisciplinary approach to its resolution. The patient comes to the consultation for mobility of the central incisor. Clinically, tooth mobility was confirmed with tooth crowding and persistence of the temporary canine. Cone beam tomography (CBCT) observed the atypical position of the permanent canine that caused root resorption of the ipsilateral central incisor and the need to extract both teeth. The conservative treatment of the bone structures during the dental enucleation of the impacted canine carried out by odontosection and the immediate bone grafting of the defect projected an acceptable regeneration of the bone volume for the insertion of the implant. The orthodontic treatment managed to correct the bite, position the upper premolar in the place of the canine tooth and maintain the space to place the implant in the central incisor. The three-year follow-up shows maintenance of the peri-implant crestal bone level, the success of orthodontic treatment with recovery of the patient’s function and aesthetics. 展开更多
关键词 Impacted Canine Unusual Transposition root resorption orthodontics/Dental Implants
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Regular nicotine intake increased tooth movement velocity,osteoclastogenesis and orthodontically induced dental root resorptions in a rat model 被引量:4
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作者 christian kirschneck michael maurer +2 位作者 michael wolf claudia reicheneder peter proff 《International Journal of Oral Science》 SCIE CAS CSCD 2017年第3期174-184,共11页
Orthodontic forces have been reported to significantly increase nicotine-induced periodontal bone loss. At present, however, it is unknown, which further (side) effects can be expected during orthodontic treatment a... Orthodontic forces have been reported to significantly increase nicotine-induced periodontal bone loss. At present, however, it is unknown, which further (side) effects can be expected during orthodontic treatment at a nicotine exposure corresponding to that of an average European smoker. 63 male Fischer344 rats were randomized in three consecutive experiments of 21 animals each (A/B/C) to 3 experimental groups (7 rats, 112/3). (A) cone-beam-computed tomography (CBCT); (B) histology/serology; (C) reverse- transcription quantitative real-time polymerase chain reaction (RT-qPCR)/cotinine serology--(1) control; (2) orthodontic tooth movement (OTM) of the first and second upper left molar (NiTi closed coil spring, 0.25 N); (3) OTM with 1.89 mg-kg- 1 per day s.c. of L(- )-nicotine. After 14 days of OTM, serum cotinine and IL-6 concentration as well as orthodontically induced inflammatory root resorption (OIIRR), osteoclast activity (histology), orthodontic tooth movement velocity (CBCT, within 14 and 28 days of OTM) and relative gene expression of known inflammatory and osteoclast markers were quantified in the dental-periodontal tissue (RT-qPCR). Animals exposed to nicotine showed significantly heightened serum cotinine and IL-6 levels corresponding to those of regular European smokers. Both the extent of root resorption, osteoclast activity, orthodontic tooth movement and gene expression of inflammatory and osteoclast markers were significantly increased compared to controls with and without OTM under the influence of nicotine. We conclude that apart from increased periodontal bone loss, a progression of dental root resorption and accelerated orthodontic tooth movement are to be anticipated during orthodontic therapy, if nicotine consumption is present. Thus patients should be informed about these risks and the necessity of nicotine abstinence during treatment. 展开更多
关键词 dental research inbred Fischer344 NICOTINE orthodontics rats root resorption tooth movement
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Apical Root Resorption in Maxillary Incisors When Employing Micro-implant and J-hook Headgear Anchorage: A 4-month Radiographic Study 被引量:5
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作者 王晴竹 陈文静 +3 位作者 Roger J Smales 彭辉 胡小坤 尹璐 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2012年第5期767-773,共7页
This study evaluated,over a 4-month study period,the amount of apical root resorption occurring in maxillary central incisors following their retraction when employing either micro-implant or J-hook headgear anchorage... This study evaluated,over a 4-month study period,the amount of apical root resorption occurring in maxillary central incisors following their retraction when employing either micro-implant or J-hook headgear anchorage.The prospective randomised clinical trial was conducted in Orthodontic Clinic,College of Stomatology,China from 2008-2009.Subjects are patients requiring fixed appliances on waiting list (n=20).In female Han Chinese patients aged from 16-26 years,standardized periapical radiographs from 10 randomly assigned patients with maxillary protrusions comprising the micro-implant group,and from 10 similar patients comprising the J-hook headgear group,were assessed for maxillary central incisor apical root resorption.Measurements before and after orthodontic therapy were also obtained from lateral cephalometric radiographs to calculate incisor horizontal retraction and vertical intrusion distances.Estimated retraction force vectors were calculated in horizontal and vertical directions for both treatment groups.Data analysis employed t-tests and the Pearson correlation test,with α=0.05 for statistical significance.The results showed that when compared with the J-hook group,significantly more apical root resorption shortening of the maxillary central incisors was observed in the micro-implant group (1.27 mm difference,95% CI=0.70-1.84,P<0.001),which was associated with a significantly larger retraction distance (P=0.004) and a smaller vertical force component (P<0.0001).We are led to conclude that continuous activation of the nickel-titanium coil springs used in the micro-implant group resulted in significantly more apical root resorption shortening and maxillary central incisor retraction than when intermittent J-hook retraction was employed.The employment of continuous duration orthodontic forces presents a risk for increased apical root resorption that requires careful radiographic monitoring. 展开更多
关键词 root resorption incisor retraction MICRO-IMPLANT J-hook
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Three-dimensional Localization of Impacted Canines and Root Resorption Assessment Using Cone Beam Computed Tomography 被引量:5
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作者 Eyad Almuhtaseb 毛靖 +2 位作者 Derek Mahony Rawan Bader 张智星 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2014年第3期425-430,共6页
Summary: The purpose of this study was to develop a new way to localize the impacted canines from three dimensions and to investigate the root resorption of the adjacent teeth by using cone beam computed tomography ... Summary: The purpose of this study was to develop a new way to localize the impacted canines from three dimensions and to investigate the root resorption of the adjacent teeth by using cone beam computed tomography (CBCT). Forty-six patients undergoing orthodontic treatments and having impacted canines in Tongii Hospital were examined. The images of CBCT scans were obtained from KaVo 3D exam vision. Angular and linear measurements of the cusp tip and root apex according to the three planes (mid-sagittal, occlusal and frontal) have been taken using the cephalometric tool of the InVivo Dental Anatomage Version 5.1.10. The measurements of the angular and linear coordinates of the maxillary and mandibular canines were obtained. Using this technique the operators could envision the location of the impacted canine according to the three clinical planes. Adjacent teeth root resorption.of 28.26 % was in the upper lateral incisors while 17.39% in upper central incisors, but no lower root resorption was found in our samples. Accurate and reliable localization of the impacted canines could be obtained from the novel analysis system, which offers a better surgical and orthodontic treatment for the patients with impacted canines. 展开更多
关键词 impacted canines root resorption cone beam computed tomography
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External Root Resorption During Standardised Orthodontic Tooth Movement In Young And Adult Rats 被引量:2
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作者 RENYi-jin JC.Maltha AMKuijpers-Jagtman 《口腔医学研究》 CAS CSCD 2004年第3期282-285,共4页
目的 :比较研究幼鼠和成年鼠正畸牙齿移动过程中的牙根吸收。方法 :本研究包括两组大鼠 ,其中幼鼠 30只 (年龄约 6周 ) ,成年鼠 30只 (年龄约 912个月 )。大鼠上颌牙一侧用于实验侧 ,另一侧用于对照。实验侧的三颗磨牙用结扎丝颌粘接剂... 目的 :比较研究幼鼠和成年鼠正畸牙齿移动过程中的牙根吸收。方法 :本研究包括两组大鼠 ,其中幼鼠 30只 (年龄约 6周 ) ,成年鼠 30只 (年龄约 912个月 )。大鼠上颌牙一侧用于实验侧 ,另一侧用于对照。实验侧的三颗磨牙用结扎丝颌粘接剂固为一个整体 ,在超弹性拉簧作用下 (力值为 0 .1牛顿 )向切牙侧移动。 1,2 ,4 ,8和 12周时给予大鼠过量麻醉剂 ,材料用于组织学研究。上颌第一磨牙的近中颊侧根为根吸收研究对象。压力侧和张力侧的牙根吸收程度在显微镜下进行长度测量。实验侧与对照侧 ,压力侧与张力侧 ,幼鼠与成年鼠之间的牙根吸收程度分别以实验时间为参照 ,在统计学手段下进行了组间和组内分析和比较 ,以探讨牙齿移动时间和年龄因素对于牙根吸收的影响。结果 :实验侧的牙根吸收在幼鼠与成年鼠之间在 1,2 ,4 ,8周时均没有统计学差异。而在第 12周时 ,成年鼠实验侧牙根吸收大于幼鼠 (P <0 .0 5 )。成年鼠实验组压力侧的牙根吸收明显大于对照组压力侧 ,而在幼鼠组没有发现这一差异。两组年龄幼鼠的实验组其压力侧和张力侧的牙根吸收均高度相关。结论 :相对于对照侧 ,正畸牙齿移动并没有在幼鼠的实验侧诱发更多的牙根吸收。在成年鼠 ,长期的正畸作用力倾向于诱发更多的牙根吸收。这些研究结果表明对于正? 展开更多
关键词 年龄 牙齿移动 牙根吸收 正畸力
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TNF-<i>α</i>and RANKL facilitates the development of orthodontically-induced inflammatory root resorption 被引量:1
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作者 Tadashi Kojima Masaru Yamaguchi +4 位作者 Tomokazu Yoshino Mami Shimizu Kunihiko Yamada Takemi Goseki Kazutaka Kasai 《Open Journal of Stomatology》 2013年第9期52-58,共7页
Background: The objective of this study was to determine the levels of tumor necrosis factor-alpha (TNF-α) and receptor activator of NF-kB ligand (RANKL) in the gingival crevicular fluid (GCF) in patients with severe... Background: The objective of this study was to determine the levels of tumor necrosis factor-alpha (TNF-α) and receptor activator of NF-kB ligand (RANKL) in the gingival crevicular fluid (GCF) in patients with severe root resorption after orthodontic treatment. Materials and Methods: Ten patients who had been receiving orthodontic treatment (5-control subjects and 5-severe root resorption subjects) participated in this study. GCF was collected from all patients. Subjects with severe root resorption (>1/3 of the original root length) were identified. Control group subjects with no loss of the root structure undergoing orthodontic treatment were also identified. The GCF was collected non-invasively from the mesial and distal sides of each of the upper central and lateral incisors using filter paper strips. The eluted GCF was used for a Western blot analysis with Antibodies against TNF-α and soluble RANKL (sRANKL). Ten male 6-week-old Wistar rats were subjected to orthodontic force of 50 g to induce a mesially tipping movement of the upper first molars for 7 days. The expression levels of TNF-α and RANKL proteins were determined in periodontal ligament (PDL) by immunohistochemical analysis. Results: The Western blot analysis showed that the TNF-α and sRANKL expressions were significantly higher in the severe root resorption group than in the control group. In the experimental tooth movement in vivo, resorption lacunae with multinucleated cells were observed in 50 g group. The immunoreactivity for TNF-α and RANKL was detected in PDL tissue subjected to the orthodontic force on day 7. Conclusion: These results suggest that TNF-α and RANKL play important roles in inducing or facilitating the development of orthodontically-induced inflammatory root resorption (OIIRR). 展开更多
关键词 TNF-α SRANKL ORTHODONTIC root resorption GINGIVAL Crevicular Fluid
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A Study of Factors Inducing Root Resorption During Functional Occlusion in Pre-orthodontic Patients 被引量:1
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作者 Sahibzadi Uzma Noor Lu Yanqin Xia Shuchi Jian Xinchun 《口腔医学研究》 CAS CSCD 北大核心 2009年第2期226-229,共4页
目的:研究未经正畸治疗的前牙有牙根吸收和无牙根吸收的错患者的及功能特征,揭示引起牙根吸收的可能的及咬合因素,为正畸治疗治疗前已有牙根吸收的患者提供可能的及功能参照标准。方法:用曲面断层片作为筛查方法,并用根尖... 目的:研究未经正畸治疗的前牙有牙根吸收和无牙根吸收的错患者的及功能特征,揭示引起牙根吸收的可能的及咬合因素,为正畸治疗治疗前已有牙根吸收的患者提供可能的及功能参照标准。方法:用曲面断层片作为筛查方法,并用根尖片进一步确诊根尖吸收,对07年7月至08年3月在我正畸科初诊的患者进行调查,从中选择14名前牙根尖吸收为Ⅱ~Ⅲ度的错畸形患者作为研究组,用年龄和性别作为控制标准随机选择14名无根尖吸收的错畸形患者作为对照组,采用临床检查、模型分析和DenarMarkⅡ架分析的方法研究两组的和功能特征,用spss14.0进行t检验统计分析。结果:两组的特征不存在差异,临床检查和架分析的结果均显示前牙牙根吸收组在侧方运动中前牙和后牙出现干扰的数量高于对照组,其中架分析发现牙根吸收患者在侧方运动中前牙出现干扰的数量显著高于对照组(P<0.05)。结论:未经治疗的错畸形患者在侧方运动过程中前牙干扰是发生前牙牙根吸收者可能原因。 展开更多
关键词 牙根吸收 [牙合] 功能
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Cone-Beam Computed Tomography Evaluation of the Positions of Unerupted Maxillary Canines with Incisor Root Resorption
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作者 Sachio Tamaoki Hiroyuki Ishikawa +4 位作者 Kyoko Oka Masao Ozaki Akiko Abe Shunsuke Takata Shozaburo Hata 《Open Journal of Stomatology》 2017年第3期169-179,共11页
Purpose: To establish a new coordinate system using the incisive canal and incisive foramen in cases confirmed to have root resorption in the maxillary incisor region by cone beam computed tomography (CBCT) to investi... Purpose: To establish a new coordinate system using the incisive canal and incisive foramen in cases confirmed to have root resorption in the maxillary incisor region by cone beam computed tomography (CBCT) to investigate the positions of the central and lateral incisor roots and erupting maxillary canine tooth crowns in the horizontal plane. Methods: Nine patients (two males;mean age: 10.5 years old) with suspected incisor root resorption due to erupting maxillary canines on panoramic X-ray images and in whom incisor root resorption was confirmed on CBCT images were evaluated. A control group of 12 patients with a supernumerary tooth on one side (three males;mean age: 8.6 years old) was also examined. X, Y, and Z-axes were defined, and the positions of the centers of the central incisor root (U1) and lateral incisor root (U2) and the canine cusp (U3) were examined, along with alveolar process width and length. Results: In the control group, U1, U2, and U3 were located within a certain range without overlap, while, in the incisor root resorption group, U3 overlapped with U1 and U2 and tended to deviate centrally. U2 tended to be located further posteriorly than U3. The anteroposterior diameter of the alveolar process was 1.2 mm shorter in the incisor root resorption group (p < 0.05). Conclusions: The risk of incisor root resorption accompanying canine eruption can be evaluated early by investigating the canine position on a horizontal plane established on the upper anterior tooth dentition CT images with a coordinate system using the incisive canal and incisive foramen. 展开更多
关键词 CBCT INCISOR root resorption MAXILLARY CANINE Incisive CANAL ALVEOLAR Process
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Evaluation of Diagnostic Efficacy of Digital Subtraction Radiography in the Diagnosis of Simulated External Root Resorption: An <i>in Vitro</i>Study
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作者 Nasim Mokhtari Goorabjavari Ahmadreza Talaeipour +2 位作者 Fatemeh Ezoddini-Ardakani Yaser Safi Nafiseh Shamloo 《Health》 2015年第4期439-448,共10页
External root resorption can induce the degeneration of dental cementum and dentine and may extend towards the pulp reductive. Digital subtraction radiography can function as a useful tool in diagnosing degenerative c... External root resorption can induce the degeneration of dental cementum and dentine and may extend towards the pulp reductive. Digital subtraction radiography can function as a useful tool in diagnosing degenerative carious lesions. This study investigated the diagnostic value of digital subtraction radiography in detecting external root resorption. This was a descriptive study conducted using the lab trial method. Artificially-induced external root resorption was created in different sizes at the coronal and apical aspects of 20 premolar teeth. Digital radiographs were obtained of each tooth under standard conditions and these radiographs were subtracted by imaging devices. The subtracted images and the digital radiographs were observed by three radiologists. Chi-square, Kappa test, and Z-test were used to analyze the data. The mean of general sensitivity of digital subtraction radiography and direct digital radiography was low in diagnosing 0.05 mm lesions (Sen = 35%), yet, the accuracy index was good for all lesions (Acc ≥ 65%). Other diagnostic parameters were also acceptable. Both types of radiography worked better in diagnosing coronal than apical lesions (P > 0.05). The interpreters (observers) showed a better performance in diagnosing external root resorption using digital subtraction radiography compared to digital radiography. Both modalities were exact and accurate in detecting 0.05 mm lesions as well as other lesions. However, the results of digital subtraction radiography were not significantly different from those of direct digital radiography. 展开更多
关键词 SUBTRACTION RADIOGRAPHY RADIOGRAPHY Direct Digital RADIOGRAPHY External root resorption
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External apical root resorption and the release of interleukin-6 in the gingival crevucular fluid induced by a self-ligating system
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作者 Ryoko Kawashima-Ichinomiya Masaru Yamaguchi +5 位作者 Yasuhiro Tanimoto Masaki Asano Kunihiko Yamada Ryo Nakajima Shoji Fujita Kazutaka Kasai 《Open Journal of Stomatology》 2012年第2期116-121,共6页
The aim of this study was to investigate the amount of external apical root resorption (EARR) and the release of interleukin (IL)-6 in the gingival crevicular fluid (GCF) in subjects treated with a low-force low-frict... The aim of this study was to investigate the amount of external apical root resorption (EARR) and the release of interleukin (IL)-6 in the gingival crevicular fluid (GCF) in subjects treated with a low-force low-friction system. Sixty patients were assigned to two groups of thirty patients for each: one group received treatment with self-ligating brackets and the other with conventional ligated edgewise brackets. All patients were treated with extraction of the maxillary first premolars. The EARR of the maxillary central incisors was evaluated on the periapical radiographs and cephalograms, taken before and after orthodontic treatment. The GCF was also collected non-invasively from the mesial and distal sides of central incisors by using filter paper strips before and after orthodontic treatment. Enzyme-linked immunosorbent assay (ELISA) kits were used to determine the IL-6 levels in the GCF samples. A significant difference was found in the amount of EARR between the patients with self-ligating brackets and conventional brackets. The mean amount of EARR was significantly lower for self-ligating brackets than conventional brackets (p < 0.05). The GCF levels of IL-6 for the patients with self-ligating brackets appliance were significantly lower than for those with the conventional brackets (p < 0.05). These results show that the mean amount of EARR and the GCF levels of IL-6 were significantly lower in the patients treated using low-force low-friction appliances than conventional brackets. Therefore, self-ligating brackets may be a useful system for reducing inflammation and EARR. 展开更多
关键词 IL-6 GINGIVAL Crevucular FLUID EXTERNAL Apical root resorption Self-Ligating BRACKETS
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Applications of stem cells in orthodontics and dentofacial orthopedics:Current trends and future perspectives 被引量:6
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作者 Shiva Safari Arezoo Mahdian Saeed Reza Motamedian 《World Journal of Stem Cells》 SCIE CAS 2018年第6期66-77,共12页
A simple overview of daily orthodontic practice involves use of brackets, wires and elastomeric modules. However, investigating the underlying effect of orthodontic forces shows various molecular and cellular changes.... A simple overview of daily orthodontic practice involves use of brackets, wires and elastomeric modules. However, investigating the underlying effect of orthodontic forces shows various molecular and cellular changes. Also, orthodontics is in close relation with dentofacial orthopedics which involves bone regeneration. In this review current and future applications of stem cells(SCs) in orthodontics and dentofacial orthopedics have been discussed. For craniofacial anomalies, SCs have been applied to regenerate hard tissue(such as treatment of alveolar cleft) and soft tissue(such as treatment of hemifacial macrosomia). Several attempts have been done to reconstruct impaired temporomandibular joint. Also, SCs with or without bone scaffolds and growth factors have been used to regenerate bone following distraction osteogenesis of mandibular bone or maxillary expansion. Current evidence shows that SCs also have potential to be used to regenerate infrabony alveolar defects and move the teeth into regenerated areas. Future application of SCs in orthodontics could involve accelerating tooth movement, regenerating resorbed roots and expanding tooth movement limitations. However, evidence supporting these roles is weak and further studies are required to evaluate the possibility of these ideas. 展开更多
关键词 Alveolar bone grafting Dentofacial DEFORMITIES Distraction osteogenesis Guided tissue regeneration orthodontics ORTHODONTIC tooth movement ORTHOGNATHIC surgery Periodontitis root resorption Stem cells
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Differences in root stress and strain distribution in buccal and lingual orthodontics: A finite element analysis study
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作者 Shengzhao Xiao Xiangfei Kong +5 位作者 Jie Yao Jinlin Liu Linhao Li Tianyun Jiang Lizhen Wang Yubo Fan 《Medicine in Novel Technology and Devices》 2022年第2期15-21,共7页
Orthodontic forces can cause stress and strain concentration and microcracks on tooth root surfaces.This study aimed to analyze whether a lingual orthodontic appliance was more likely to cause root stress concentratio... Orthodontic forces can cause stress and strain concentration and microcracks on tooth root surfaces.This study aimed to analyze whether a lingual orthodontic appliance was more likely to cause root stress concentration and root resorption than the traditional buccal appliance.A finite element model of the root of the maxillary central incisor with straight,buccal,and lingual curvatures was established.A load perpendicular to the tooth surface on the buccal and lingual surfaces of the central incisor was applied,and the stress and strain concentration at the root apex was compared.The stress and strain at the root apex of the lingual cingulum group were lesser than those of the buccal group;little difference was observed between the lingual and buccal clinical crown central augmentation groups.The stress and strain at the root apex of the lingual direction movement group were greater than those of the buccal direction movement group.The direction of the root curvature also influenced the amount of stress and strain at the root apex.The difference in the risk of root resorption between lingual and buccal orthodontics is dependent on the height of the bracket placement.The loading direction of the orthodontic force and direction of the root curvature also affect the stress and strain at the root apex. 展开更多
关键词 root resorption Orthodontic force Finite element model Lingual orthodontics
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Root Resorption in Anterior Open Bite Malocclusions Due to Vertical Correction: A Radiometric Pilot Study
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作者 Suhina Kapoor David Briss +1 位作者 Shuying Jiang Thomas J. Cangialosi 《Open Journal of Orthopedics》 2023年第6期233-245,共13页
Introduction: One of the most common risks of fixed orthodontic therapy is the evidence of root resorption post orthodontic treatment ranging from mild root blunting to severe root resorption of significant portions o... Introduction: One of the most common risks of fixed orthodontic therapy is the evidence of root resorption post orthodontic treatment ranging from mild root blunting to severe root resorption of significant portions of the root structure. The etiology of apical root resorption is multifactorial but largely depends upon the type of orthodontic tooth movement and treatment duration. Study Objective: The primary aim of this study is to examine the association of external apical root resorption and vertical correction in anterior open bite malocclusions using panoramic radiographs for evaluation. Materials and Methods: Pre-treatment and post-treatment panoramic radiographs of 16 patients with anterior open bite malocclusions were scored to assess root resorption of anterior teeth (U/L 3-3). Initial and final root length and total tooth length for U/L 3-3 were measured on panoramic radiographs in Dolphin imaging. Results: Of the 24 pairs of measurements, 7 had a significant p-value (p Conclusions: A statistically significant amount of root resorption was observed, from pre-treatment to post-treatment radiographs. All mandibular anterior teeth except the mandibular right lateral incisors showed evidence of root resorption. 展开更多
关键词 Open bite malocclusion External apical root resorption Open bite closure
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Bioceramics utilization for the repair of internal resorption of the root:A case report
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作者 Abdullah Mahmoud Riyahi 《World Journal of Clinical Cases》 SCIE 2022年第30期11185-11189,共5页
BACKGROUND The objective of this work is displaying a successful treatment for an internal resorption case under operating microscope using bioceramic material.CASE SUMMARY Periapical radiograph showed radiolucent les... BACKGROUND The objective of this work is displaying a successful treatment for an internal resorption case under operating microscope using bioceramic material.CASE SUMMARY Periapical radiograph showed radiolucent lesion representing large internal resorption of the root.The respective defect was obturated using endoscquence bioceramic material follow up at the month 18 after treatment revealed no abnormal finings clinically and radiographically.CONCLUSION New generations bioceramics have many advantages that internal root resorption cases can benefit from.The use of operating microscope helps to apply obturating materials with precision.However,long term study on a large sample is required in future studies. 展开更多
关键词 resorption root Treatment Internal BIOCERAMICS ENDODONTICS Case report
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Low-intensity pulsed ultrasound reduces alveolar bone resorption during orthodontic treatment via Lamin A/C-Yes-associated protein axis in stem cells 被引量:1
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作者 Tong Wu Fu Zheng +7 位作者 Hong-Yi Tang Hua-Zhi Li Xin-Yu Cui Shuai Ding Duo Liu Cui-Ying Li Jiu-Hui Jiang Rui-Li Yang 《World Journal of Stem Cells》 SCIE 2024年第3期267-286,共20页
BACKGROUND The bone remodeling during orthodontic treatment for malocclusion often requires a long duration of around two to three years,which also may lead to some complications such as alveolar bone resorption or to... BACKGROUND The bone remodeling during orthodontic treatment for malocclusion often requires a long duration of around two to three years,which also may lead to some complications such as alveolar bone resorption or tooth root resorption.Low-intensity pulsed ultrasound(LIPUS),a noninvasive physical therapy,has been shown to promote bone fracture healing.It is also reported that LIPUS could reduce the duration of orthodontic treatment;however,how LIPUS regulates the bone metabolism during the orthodontic treatment process is still unclear.AIM To investigate the effects of LIPUS on bone remodeling in an orthodontic tooth movement(OTM)model and explore the underlying mechanisms.METHODS A rat model of OTM was established,and alveolar bone remodeling and tooth movement rate were evaluated via micro-computed tomography and staining of tissue sections.In vitro,human bone marrow mesenchymal stem cells(hBMSCs)were isolated to detect their osteogenic differentiation potential under compression and LIPUS stimulation by quantitative reverse transcription-polymerase chain reaction,Western blot,alkaline phosphatase(ALP)staining,and Alizarin red staining.The expression of Yes-associated protein(YAP1),the actin cytoskeleton,and the Lamin A/C nucleoskeleton were detected with or without YAP1 small interfering RNA(siRNA)application via immunofluorescence.RESULTS The force treatment inhibited the osteogenic differentiation potential of hBMSCs;moreover,the expression of osteogenesis markers,such as type 1 collagen(COL1),runt-related transcription factor 2,ALP,and osteocalcin(OCN),decreased.LIPUS could rescue the osteogenic differentiation of hBMSCs with increased expression of osteogenic marker inhibited by force.Mechanically,the expression of LaminA/C,F-actin,and YAP1 was downregulated after force treatment,which could be rescued by LIPUS.Moreover,the osteogenic differentiation of hBMSCs increased by LIPUS could be attenuated by YAP siRNA treatment.Consistently,LIPUS increased alveolar bone density and decreased vertical bone absorption in vivo.The decreased expression of COL1,OCN,and YAP1 on the compression side of the alveolar bone was partially rescued by LIPUS.CONCLUSION LIPUS can accelerate tooth movement and reduce alveolar bone resorption by modulating the cytoskeleton-Lamin A/C-YAP axis,which may be a promising strategy to reduce the orthodontic treatment process. 展开更多
关键词 Low-intensity pulsed ultrasound Bone resorption OSTEOGENESIS Cytoskeleton-Lamin A/C-Yes-associated protein axis Bone marrow mesenchymal stem cells Orthodontic tooth movement
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3D打印个性化正畸装置对单根牙垂直移动的三维有限元分析
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作者 曹怡琳 王心彧 +5 位作者 庄妍 王亚茹 姜至秀 刘丹瑜 门九旭 丁元圣 《中国组织工程研究》 CAS 北大核心 2025年第16期3360-3368,共9页
背景:基于牙齿垂直移动原理,通过数字化设计结合3D打印制作个性化正畸装置,可使个性化正畸装置与单个切牙形成支抗系统。借助微种植体绝对支抗作用可对单根牙在三维方向上进行精准控制。目的:基于生物力学原理设计了牙位11、12、21、22... 背景:基于牙齿垂直移动原理,通过数字化设计结合3D打印制作个性化正畸装置,可使个性化正畸装置与单个切牙形成支抗系统。借助微种植体绝对支抗作用可对单根牙在三维方向上进行精准控制。目的:基于生物力学原理设计了牙位11、12、21、22压低移动与伸长移动的个性化正畸装置,通过三维有限元法分析个性化正畸装置的安全性与其对牙齿的移动作用。方法:应用Mimics、Geomagic Wrap、SolidWorks和Ansys Workbench软件分别建立了上颌前牙区(牙位11、12、21、22)牙槽骨-牙周膜-上颌切牙-个性化悬臂微种植体-连接板-个性化托槽的三维有限元模型,每个牙位分别设置个性化压低移动与伸长移动正畸装置,加载300 g拉力或推力,分析个性化正畸装置各部件应力水平,计算牙齿位移与牙周膜应力分布情况。结果与结论:①个性化压低移动正畸装置受到的最大等效应力为162.90 MPa,个性化伸长移动正畸装置受到的最大等效应力239.57 MPa,二者的最大等效应力均位于个性化托槽加力附件的垂直部分,个性化正畸装置各部件所受等效应力均在屈服强度内,均具有良好的安全性;②在个性化正畸装置作用下,牙齿初始位移呈现整体压低或伸长移动的趋势,垂直方向上的位移远远超过在水平方向和矢状方向上的位移;牙周膜根尖或颈部位置出现等效应力峰值,在根尖区牙周膜出现等效应力集中区域;③结果显示,个性化正畸装置可以使牙位11、12、21、22近似达到压低移动或伸长移动的目的,初步证实了个性化垂直移动正畸装置的有效性。 展开更多
关键词 3D打印个性化正畸装置 单根牙 压低移动 伸长移动 三维有限元分析 支抗 生物力学
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iRoot■BP^(+Plus)根尖倒充填修复上颌中切牙牙根外吸收1例 被引量:4
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作者 王聃 张绍俊 +1 位作者 武传君 全鹤 《实用口腔医学杂志》 CAS CSCD 北大核心 2022年第2期272-274,共3页
报告1例外伤后发生牙根外吸收的上颌中切牙,经显微根尖手术行超声器械根管倒预备、iRoot■BP^(+Plus)根管倒充填及牙根外形修复,取得较好临床效果病例。术后定期回访2年,效果稳定。
关键词 牙根外吸收 显微根尖手术 iroot■BP+Plus
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Fate of root shell after pontic/socket shield techniques,is it better to extract the whole tooth? 被引量:1
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作者 Amit Arvind Agrawal 《World Journal of Meta-Analysis》 2021年第4期333-341,共9页
A series of changes occur in the remaining alveolar process after whole tooth extraction.The basic question is,why do the bony walls(especially the labial/buccal)get resorbed immediately after the tooth is removed?Thi... A series of changes occur in the remaining alveolar process after whole tooth extraction.The basic question is,why do the bony walls(especially the labial/buccal)get resorbed immediately after the tooth is removed?This could be because,with cementum of the concerned tooth and its periodontal ligament,the supporting bundle bone is dependent on the presence of the tooth.This loss can be compensated using numerous techniques,such as socket grafting using various biomaterials to preserve the alveolar bone and buccal grafting with guided tissue regeneration to increase the thickness of buccal bone or placement of implant immediately.However,none of these techniques prevent the modelling of the alveolar bone post-extraction.Few studies have demonstrated that preservation of the roots in the alveolar process maintains the bone volume and facilitates vertical bone growth.A histological study in animals and humans has shown that the retained root shell does not pose any interference in the osseointegration of the implant(if placed simultaneously).Although various names have been proposed to describe the concept of retaining full or part of the root to prevent the resorption of the ridge,socket-shield and pontic-shield are the two most commonly used terms worldwide.The extraction of the whole tooth might be the choice of therapy when socket-shield or pontic-shield is not possible due to anatomical variations,infections,or lack of clinical expertise.Irrespective of the size,when a whole root or a root fragment(is left in situ),it is the dentist’s ethical duty to advise/inform the patient and ensure repeated clinical and radiographic follow-up.The present study aimed to highlight the current status of these techniques,their benefits,and possible complications and address whether the paradigm of the teeth extraction methods should be altered. 展开更多
关键词 Socket shield technique Pontic shield technique Alveolar resorption Tooth root Tooth extraction Ridge preservation Alveolar resorption
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Non-Invasive management of invasive cervical resorption associated with periodontal pocket: A case report
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作者 Abdullah Alqedairi 《World Journal of Clinical Cases》 SCIE 2019年第7期863-871,共9页
BACKGROUND Invasive cervical resorption(ICR), a commonly misdiagnosed condition, is an aggressive form of external tooth resorption that contributes to periodontal tissue inflammation and deepening of the periodontal ... BACKGROUND Invasive cervical resorption(ICR), a commonly misdiagnosed condition, is an aggressive form of external tooth resorption that contributes to periodontal tissue inflammation and deepening of the periodontal pockets. Herein we report the case of a patient, exhibiting ICR and elaborate the effects of a non-surgical approach in the amelioration of this condition.CASE SUMMARY A 21-year-old female reporting intermittent pain at the upper left side, multiple restorations, no trauma history, and having received orthodontic treatment was studied. Localized erythematous swelling was noted at the buccal interdental papilla between the left maxillary first molar and second premolar. The diseased pulp and tissue in resorption were removed and the root canal system including the defect were sealed using gutta percha/AH Plus and mineral trioxide aggregate(MTA). At the one-year recall, the tooth showed no symptoms and responded normally to percussion and palpation. The surrounding periodontium exhibited a normal color and the probing depth was normal. Radiographic examination showed a restoration of crestal alveolar bone and good adaption to MTA.CONCLUSION Non-surgical root canal treatment in conjunction with resorption defect orthograde repair with MTA was found to be an effective treatment option in the elimination of ICR. Early diagnoses are recommended in order to employ nonsurgical approaches for management of ICR instead of surgical interventions. 展开更多
关键词 INVASIVE CERVICAL resorption Mineral TRIOXIDE aggregate NON-SURGICAL root canal PERIODONTAL Case report
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隐形矫治器设计上切牙压低量对牙根吸收的影响分析 被引量:1
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作者 张莹莹 王斌 《中国医疗美容》 2024年第2期70-73,共4页
目的研究在隐形矫治技术中上颌中切牙的压低量与牙根吸收的关系。方法纳入于合肥市口腔医院正畸一科采用隐形矫治技术治疗深覆牙合的非拔牙患者62例,在正畸治疗前(T0)、压低量1 mm时(T1)和压低量2 mm时(T2)进行三次CBCT追踪检查。测量... 目的研究在隐形矫治技术中上颌中切牙的压低量与牙根吸收的关系。方法纳入于合肥市口腔医院正畸一科采用隐形矫治技术治疗深覆牙合的非拔牙患者62例,在正畸治疗前(T0)、压低量1 mm时(T1)和压低量2 mm时(T2)进行三次CBCT追踪检查。测量三个时期上切牙牙根长度、牙根体积和唇腭侧牙槽骨高度,运用SPSS 26.0软件进行统计学分析。结果牙根吸收与压低量呈正相关(P<0.05);压低量越大,切牙唇倾度越大(P<0.05);三个阶段的唇侧牙槽骨高度无统计学差异(P>0.05),腭侧牙槽骨高度的差异有统计学意义(P<0.05),T2期腭侧牙槽骨吸收明显;牙根吸收与治疗时间呈正相关(P<0.05)。结论隐形矫治技术中上颌中切牙牙根吸收与压低量有关。 展开更多
关键词 牙根吸收 压低量 上颌中切牙 无托槽隐形矫治器 牙槽骨
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