To examine accuracy of body composition predicted by the Multi-Frequency Bioelectric Impedance Analysis （MF-BIA） compared with the Dual-energy X-ray Absorptiometry （DXA） in adults with obese. We measured body comp...To examine accuracy of body composition predicted by the Multi-Frequency Bioelectric Impedance Analysis （MF-BIA） compared with the Dual-energy X-ray Absorptiometry （DXA） in adults with obese. We measured body composition of 749 adults with obese both by the MF-BIA and DXA. The Lin＇s concordance correlation and the Bland-Altman plots were used to examine the consistency. The concordance correlation coefficient of %BF between the MF-BIA and DXA in men and women was 0.560, and 0.669, respectively. Compared with the DXA, the MF-BIA significantly underestimated %BF by 4.33% in men （P 〈 0.001）, however overestimated %BF by 0.50% in women （P 〈 0.001）. After corrected by the correction equations established in this study, the differences were significantly decreased. Therefore, the MF-BIA （TANITA MC-180） may need to be corrected in estimating body composition for adults with obese.展开更多
AIM: To assess:(1) Whether the World Health Organization fracture risk assessment tool(FRAX) can be used for monitoring osteoporosis patients receiving treatment as well as its clinical implications; and(2) The relati...AIM: To assess:(1) Whether the World Health Organization fracture risk assessment tool(FRAX) can be used for monitoring osteoporosis patients receiving treatment as well as its clinical implications; and(2) The relation between fracture incidence and post-treatment FRAX.METHODS: Five hundred and seventy-nine osteoporotic women known to be adherent to the prescribed osteoporosis medication, had dual-energy X-ray absorptiometry scan and fracture probability calculated at baseline, 2 and 5-year of osteoporosis treatment. Those patients who responded to treatment and did not sustain a new low trauma fracture during the first 2 years, continued their treatment and were re-assessed 3-year later. The patient subgroup who did not achieve an improvement in their bone mineral density(BMD)or sustain any fracture within the first 2-year, had their osteoporosis treatment changed. Outcome measures included BMD and FRAX assessment calculated 3-year after commencing new osteoporosis treatment. RESULTS: There was a significant negative correlation between 10-year probability of major osteoporotic and hip fractures and BMD at the total proximal femur at 2-year of treatment(R =-0.449 and-0.479 respectively), and at 5-year(R =-0.489 and-0.594 respectively). At both 2 years and 5 years of treatment, the 10-year fracture probability showed significant correlation with the incidence of fracture(P < 0.01). On comparing fracture probability, there was a significant difference(P < 0.05) between the responders and non-responders to osteoporosis treatment.CONCLUSION: In women currently or previously treated for osteoporosis, the FRAX tool can be used to predict fracture probability. Osteoporosis treatment does not annul prediction of fractures. FRAX tool may be of value in guiding clinicians towards the need for continuation or withdrawal of treatment.展开更多
近年来,我国肉类加工行业发展迅猛,自动化和智能化水平逐渐提高,多种肥瘦比例检测技术被应用到肉制品加工和屠宰行业。双能X射线吸收法(dual energy X-ray absorptiometry,DXA)是解决肉制品在线肥瘦比例检测的最佳方法之一,具有精准度...近年来,我国肉类加工行业发展迅猛,自动化和智能化水平逐渐提高,多种肥瘦比例检测技术被应用到肉制品加工和屠宰行业。双能X射线吸收法(dual energy X-ray absorptiometry,DXA)是解决肉制品在线肥瘦比例检测的最佳方法之一,具有精准度高、耗时短、可以对胴体全身进行检测的优势。本文比较当前各种肥瘦比例检测技术的特点,介绍DXA的概念、测量方式,重点探讨DXA在肥瘦比例测定中的应用和研究进展,通过对研究现状、设备类型和存在问题的分析,讨论未来该技术应用的发展方向。展开更多
Background The performance of computed tomography X-ray absorptiometry （CTXA） against the dual energy X-ray absorptiometry （DXA） as standard has not been studied in Chinese population. The aim of this study was to...Background The performance of computed tomography X-ray absorptiometry （CTXA） against the dual energy X-ray absorptiometry （DXA） as standard has not been studied in Chinese population. The aim of this study was to evaluate the precision of this measurement and validate the value of quantitative computed tomography （QCT） by comparing CTXA results with DXA results in an elderly Chinese population. Methods One hundred and three females of 46 to 76 years old and 49 males of 52 to 76 years old were recruited from the Prospective Urban Rural Epidemiology study. All subjects underwent hip scans by both QCT and DXA on the same day. For precision determination, 30 subjects had duplicate DXA hip scans. The hip QCT data of a subset of 27 subjects were separately analyzed by two observers and reanalyzed by one observer at a different time. The inter- and intra-observer variations of CTXA measurement were assessed, and the difference and correlation between CTXA and DXA results were analyzed. Results The inter- and intra-observer variations of CTXA were 0.070 and 0.024 g/cm^2 in the femoral neck （FN）, and 0.030 and 0.012 g/cm2 in the total hip （TH）, which were comparable to the DXA inter-scan variations （0.013 g/cm2 for FN and 0.014 g/cm2 for TH）. The results of CTXA bone mineral density （BMD） were highly correlated with those of DXA （R2 = 0.810 for FN and R2 = 0.878 for TH）. The BMD values of CTXA in FN and TH were lower than those of DXA by 21.0% and 17.8% （P〈0.05）, respectively. However, after appropriate transformation, the difference was eliminated and a comparable T score could be obtained. Conclusions CTXA shows good agreement with DXA for the measurement of BMD in the proximal femur, which makes QCT suitable for the quantification of bone mineral content in the hip and helpful for the diagnosis of osteoporosis.展开更多
目的观察绝经后中国女性跟骨定量超声和双能X线检查骨质疏松症的效果比较。方法评估234名绝经后未接受过治疗的40~80岁女性的腰椎、双侧股骨颈和全髋关节部位的骨密度(bone mineral density,BMD)的DXA参数和左右跟骨的QUS参数。计算BMD...目的观察绝经后中国女性跟骨定量超声和双能X线检查骨质疏松症的效果比较。方法评估234名绝经后未接受过治疗的40~80岁女性的腰椎、双侧股骨颈和全髋关节部位的骨密度(bone mineral density,BMD)的DXA参数和左右跟骨的QUS参数。计算BMD和QUS参数的相关系数。生成接收器操作特性曲线,并评估曲线下面积(area under curve,AUC)来定义QUS的截止值。结果跟骨QUS能够识别右侧髋关节(AUC,0.887)和左股骨颈(AUC,0.824)的T值为-2.5或更低的绝经后妇女。为了筛选目的,定义了右侧(1.455)和左侧(1.480)跟骨的QUS T值的截止值。结论与DXA这种标准的诊断方法相比,可以推荐QUS作为预筛选工具来减少DXA筛查的数量。展开更多
文摘To examine accuracy of body composition predicted by the Multi-Frequency Bioelectric Impedance Analysis （MF-BIA） compared with the Dual-energy X-ray Absorptiometry （DXA） in adults with obese. We measured body composition of 749 adults with obese both by the MF-BIA and DXA. The Lin＇s concordance correlation and the Bland-Altman plots were used to examine the consistency. The concordance correlation coefficient of %BF between the MF-BIA and DXA in men and women was 0.560, and 0.669, respectively. Compared with the DXA, the MF-BIA significantly underestimated %BF by 4.33% in men （P 〈 0.001）, however overestimated %BF by 0.50% in women （P 〈 0.001）. After corrected by the correction equations established in this study, the differences were significantly decreased. Therefore, the MF-BIA （TANITA MC-180） may need to be corrected in estimating body composition for adults with obese.
文摘AIM: To assess:(1) Whether the World Health Organization fracture risk assessment tool(FRAX) can be used for monitoring osteoporosis patients receiving treatment as well as its clinical implications; and(2) The relation between fracture incidence and post-treatment FRAX.METHODS: Five hundred and seventy-nine osteoporotic women known to be adherent to the prescribed osteoporosis medication, had dual-energy X-ray absorptiometry scan and fracture probability calculated at baseline, 2 and 5-year of osteoporosis treatment. Those patients who responded to treatment and did not sustain a new low trauma fracture during the first 2 years, continued their treatment and were re-assessed 3-year later. The patient subgroup who did not achieve an improvement in their bone mineral density(BMD)or sustain any fracture within the first 2-year, had their osteoporosis treatment changed. Outcome measures included BMD and FRAX assessment calculated 3-year after commencing new osteoporosis treatment. RESULTS: There was a significant negative correlation between 10-year probability of major osteoporotic and hip fractures and BMD at the total proximal femur at 2-year of treatment(R =-0.449 and-0.479 respectively), and at 5-year(R =-0.489 and-0.594 respectively). At both 2 years and 5 years of treatment, the 10-year fracture probability showed significant correlation with the incidence of fracture(P < 0.01). On comparing fracture probability, there was a significant difference(P < 0.05) between the responders and non-responders to osteoporosis treatment.CONCLUSION: In women currently or previously treated for osteoporosis, the FRAX tool can be used to predict fracture probability. Osteoporosis treatment does not annul prediction of fractures. FRAX tool may be of value in guiding clinicians towards the need for continuation or withdrawal of treatment.
文摘近年来,我国肉类加工行业发展迅猛,自动化和智能化水平逐渐提高,多种肥瘦比例检测技术被应用到肉制品加工和屠宰行业。双能X射线吸收法(dual energy X-ray absorptiometry,DXA)是解决肉制品在线肥瘦比例检测的最佳方法之一,具有精准度高、耗时短、可以对胴体全身进行检测的优势。本文比较当前各种肥瘦比例检测技术的特点,介绍DXA的概念、测量方式,重点探讨DXA在肥瘦比例测定中的应用和研究进展,通过对研究现状、设备类型和存在问题的分析,讨论未来该技术应用的发展方向。
文摘Background The performance of computed tomography X-ray absorptiometry （CTXA） against the dual energy X-ray absorptiometry （DXA） as standard has not been studied in Chinese population. The aim of this study was to evaluate the precision of this measurement and validate the value of quantitative computed tomography （QCT） by comparing CTXA results with DXA results in an elderly Chinese population. Methods One hundred and three females of 46 to 76 years old and 49 males of 52 to 76 years old were recruited from the Prospective Urban Rural Epidemiology study. All subjects underwent hip scans by both QCT and DXA on the same day. For precision determination, 30 subjects had duplicate DXA hip scans. The hip QCT data of a subset of 27 subjects were separately analyzed by two observers and reanalyzed by one observer at a different time. The inter- and intra-observer variations of CTXA measurement were assessed, and the difference and correlation between CTXA and DXA results were analyzed. Results The inter- and intra-observer variations of CTXA were 0.070 and 0.024 g/cm^2 in the femoral neck （FN）, and 0.030 and 0.012 g/cm2 in the total hip （TH）, which were comparable to the DXA inter-scan variations （0.013 g/cm2 for FN and 0.014 g/cm2 for TH）. The results of CTXA bone mineral density （BMD） were highly correlated with those of DXA （R2 = 0.810 for FN and R2 = 0.878 for TH）. The BMD values of CTXA in FN and TH were lower than those of DXA by 21.0% and 17.8% （P〈0.05）, respectively. However, after appropriate transformation, the difference was eliminated and a comparable T score could be obtained. Conclusions CTXA shows good agreement with DXA for the measurement of BMD in the proximal femur, which makes QCT suitable for the quantification of bone mineral content in the hip and helpful for the diagnosis of osteoporosis.
文摘目的观察绝经后中国女性跟骨定量超声和双能X线检查骨质疏松症的效果比较。方法评估234名绝经后未接受过治疗的40~80岁女性的腰椎、双侧股骨颈和全髋关节部位的骨密度(bone mineral density,BMD)的DXA参数和左右跟骨的QUS参数。计算BMD和QUS参数的相关系数。生成接收器操作特性曲线,并评估曲线下面积(area under curve,AUC)来定义QUS的截止值。结果跟骨QUS能够识别右侧髋关节(AUC,0.887)和左股骨颈(AUC,0.824)的T值为-2.5或更低的绝经后妇女。为了筛选目的,定义了右侧(1.455)和左侧(1.480)跟骨的QUS T值的截止值。结论与DXA这种标准的诊断方法相比,可以推荐QUS作为预筛选工具来减少DXA筛查的数量。
