Primarily healthy women who attended a practice of General Medicine were examined and coded data were evaluated using two statistical methods (n = 248, aged 36 ± 14 years). It was found that participants with LDL...Primarily healthy women who attended a practice of General Medicine were examined and coded data were evaluated using two statistical methods (n = 248, aged 36 ± 14 years). It was found that participants with LDL-related (mixed) hyperlipidemia showed higher blood pressure, a higher proportion of alcohol problems and/or smoking compared to normolipidemic women (p ≤ 0.05). These hyperlipidemic women who reported alcohol problems and/or smoking more often showed proteinuria and/or hematuria, rise of LDL/HDL, critical fasting blood glucose and lower HDL-cholesterol compared to hyperlipidemic women reporting healthy lifestyle (p ≤ 0.05). Likewise, high triglycerides were associated with rise of blood pressure and intolerance to glucose (p ≤ 0.05) and also with elevated total cholesterol. Alcohol-related hypertriglyceridemia overlapped with diastolic hypertension, rise of body weight and urine pathology, lowering of HDL-cholesterol and critical fasting blood glucose. The motivating message was that women with mixed hyperlipidemia and healthy lifestyle had functionally renal endothelium and healthy HDL-related baseline measures. Altogether, LDL-related hyperlipidemia and/or high triglycerides were correlated with diastolic hypertension whereby critical alcohol consumption declined renal endothelium and lowered HDL-cholesterol implicating baseline strategies to neutralize early risk factors.展开更多
Objective: To evaluate the effectiveness of a dietary intervention to increase target vegetable intake in overweight, postpartum mothers;and their children. Methods: Overweight mothers attending their six-week postpar...Objective: To evaluate the effectiveness of a dietary intervention to increase target vegetable intake in overweight, postpartum mothers;and their children. Methods: Overweight mothers attending their six-week postpartum follow-up visit and their infants (n = 104 pairs) were randomized to intervention or usual care groups during the time period 2008-2011. Mothers received four 60 minute education sessions with a nutrition professional and eight monthly follow-up phone calls. Counseling began at the obstetrician office and continued at the regularly scheduled pediatric visits. The primary study outcome was the change in maternal target vegetable intake. Secondary outcomes included child target vegetable intake and whether child vegetable intake was modified by exposure to breastfeeding. Mother/child energy intake and weight indices were also assessed. Outcomes were measured at baseline (6-weeks postpartum), 6, 12 (post-intervention), and 18 (follow-up) months. Mixed-effects models were used to estimate the impact of the dietary intervention on study outcomes relative to usual care. Results: Mothers randomized to the intervention had greater consumption of target vegetables at 6, 12 and 18 months (P P P = 0.03, respectively). There were no differences between groups in maternal energy intake, body mass index, or child target vegetable or energy intake. The child’s target vegetable intake at 12 months was related to the mother’s intake at 6 months (P = 0.03), however, this relationship was not modified by exposure to breastfeeding. Conclusion: A dietary intervention targeting the diet of the mother/child dyad resulted in improved maternal vegetable intake.展开更多
目的探讨运动疗法对超重或肥胖孕妇孕期并发症和妊娠结局的影响。方法计算机检索Pub Med、Cochrane Library、Embase、Web of Science、中国生物医学文献数据库(CBM)、中国知网(CNKI)、万方数据库。全面检索运动疗法对超重或肥胖孕妇孕...目的探讨运动疗法对超重或肥胖孕妇孕期并发症和妊娠结局的影响。方法计算机检索Pub Med、Cochrane Library、Embase、Web of Science、中国生物医学文献数据库(CBM)、中国知网(CNKI)、万方数据库。全面检索运动疗法对超重或肥胖孕妇孕期并发症和妊娠结局影响的相关研究。采用Cochrane系统评价方法 ,对纳入文献进行质量评价,并使用Rev Man 5.3软件对资料进行Meta分析。结果共纳入9篇随机对照试验,1 444例患者。Meta分析结果显示:运动疗法可降低妊娠期糖尿病的发生率(RR=0.52,95%CI:0.39~0.68,P<0.001)、妊娠期高血压疾病的发生率(RR=0.62,95%CI:0.45~0.84,P=0.002)、剖宫产发生率(RR=0.83,95%CI:0.70~0.98,P=0.030)、早产发生率(RR=0.55,95%CI:0.31~0.98,P=0.040),产后出血发生率(RR=0.28,95%CI:0.15~0.52,P<0.001)、巨大儿发生率(RR=0.15,95%CI:0.08~0.27,P<0.001)、新生儿窒息发生率(RR=0.33,95%CI:0.18~0.60,P<0.001)。结论运动疗法可降低超重或肥胖孕妇孕期并发症的发生,改善不良妊娠结局。展开更多
文摘Primarily healthy women who attended a practice of General Medicine were examined and coded data were evaluated using two statistical methods (n = 248, aged 36 ± 14 years). It was found that participants with LDL-related (mixed) hyperlipidemia showed higher blood pressure, a higher proportion of alcohol problems and/or smoking compared to normolipidemic women (p ≤ 0.05). These hyperlipidemic women who reported alcohol problems and/or smoking more often showed proteinuria and/or hematuria, rise of LDL/HDL, critical fasting blood glucose and lower HDL-cholesterol compared to hyperlipidemic women reporting healthy lifestyle (p ≤ 0.05). Likewise, high triglycerides were associated with rise of blood pressure and intolerance to glucose (p ≤ 0.05) and also with elevated total cholesterol. Alcohol-related hypertriglyceridemia overlapped with diastolic hypertension, rise of body weight and urine pathology, lowering of HDL-cholesterol and critical fasting blood glucose. The motivating message was that women with mixed hyperlipidemia and healthy lifestyle had functionally renal endothelium and healthy HDL-related baseline measures. Altogether, LDL-related hyperlipidemia and/or high triglycerides were correlated with diastolic hypertension whereby critical alcohol consumption declined renal endothelium and lowered HDL-cholesterol implicating baseline strategies to neutralize early risk factors.
文摘Objective: To evaluate the effectiveness of a dietary intervention to increase target vegetable intake in overweight, postpartum mothers;and their children. Methods: Overweight mothers attending their six-week postpartum follow-up visit and their infants (n = 104 pairs) were randomized to intervention or usual care groups during the time period 2008-2011. Mothers received four 60 minute education sessions with a nutrition professional and eight monthly follow-up phone calls. Counseling began at the obstetrician office and continued at the regularly scheduled pediatric visits. The primary study outcome was the change in maternal target vegetable intake. Secondary outcomes included child target vegetable intake and whether child vegetable intake was modified by exposure to breastfeeding. Mother/child energy intake and weight indices were also assessed. Outcomes were measured at baseline (6-weeks postpartum), 6, 12 (post-intervention), and 18 (follow-up) months. Mixed-effects models were used to estimate the impact of the dietary intervention on study outcomes relative to usual care. Results: Mothers randomized to the intervention had greater consumption of target vegetables at 6, 12 and 18 months (P P P = 0.03, respectively). There were no differences between groups in maternal energy intake, body mass index, or child target vegetable or energy intake. The child’s target vegetable intake at 12 months was related to the mother’s intake at 6 months (P = 0.03), however, this relationship was not modified by exposure to breastfeeding. Conclusion: A dietary intervention targeting the diet of the mother/child dyad resulted in improved maternal vegetable intake.
文摘目的探讨运动疗法对超重或肥胖孕妇孕期并发症和妊娠结局的影响。方法计算机检索Pub Med、Cochrane Library、Embase、Web of Science、中国生物医学文献数据库(CBM)、中国知网(CNKI)、万方数据库。全面检索运动疗法对超重或肥胖孕妇孕期并发症和妊娠结局影响的相关研究。采用Cochrane系统评价方法 ,对纳入文献进行质量评价,并使用Rev Man 5.3软件对资料进行Meta分析。结果共纳入9篇随机对照试验,1 444例患者。Meta分析结果显示:运动疗法可降低妊娠期糖尿病的发生率(RR=0.52,95%CI:0.39~0.68,P<0.001)、妊娠期高血压疾病的发生率(RR=0.62,95%CI:0.45~0.84,P=0.002)、剖宫产发生率(RR=0.83,95%CI:0.70~0.98,P=0.030)、早产发生率(RR=0.55,95%CI:0.31~0.98,P=0.040),产后出血发生率(RR=0.28,95%CI:0.15~0.52,P<0.001)、巨大儿发生率(RR=0.15,95%CI:0.08~0.27,P<0.001)、新生儿窒息发生率(RR=0.33,95%CI:0.18~0.60,P<0.001)。结论运动疗法可降低超重或肥胖孕妇孕期并发症的发生,改善不良妊娠结局。
