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Synthesis of urea acetates as potential PPARα/γ dual agonists
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作者 Chang Yan Zhao Chang Qing Shi Yuan Wei Chen 《Chinese Chemical Letters》 SCIE CAS CSCD 2008年第2期166-168,共3页
In the quest for novel PPARα/γ dual agonists as putative drugs for the treatment of type 2 diabetes and dyslipidemia, we designed and synthesized a series of urea acetates as potential PPARα/γ dual agonists. The s... In the quest for novel PPARα/γ dual agonists as putative drugs for the treatment of type 2 diabetes and dyslipidemia, we designed and synthesized a series of urea acetates as potential PPARα/γ dual agonists. The structure of the target compounds, intermediates were characterized by ^1H N-MR, HRMS. 展开更多
关键词 oxazolc PPAR agonist Type 2 diabetes UREA AMMONOLYSIS Synthesis
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