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非线性M-C强度准则下预应力锚索加固边坡时效稳定性分析M-P法 被引量:1
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作者 邓东平 杨春会 谢志军 《岩土力学》 EI CAS CSCD 北大核心 2024年第4期1051-1066,共16页
拓展传统极限平衡方法在复杂条件下边坡稳定性分析中的适用性一直是岩土工程界的研究热点。众所周知,边坡岩土体剪切失效一般服从于非线性强度准则,而传统极限平衡方法仅适用于线性强度准则下边坡稳定性分析。此外,预应力锚索作为一种... 拓展传统极限平衡方法在复杂条件下边坡稳定性分析中的适用性一直是岩土工程界的研究热点。众所周知,边坡岩土体剪切失效一般服从于非线性强度准则,而传统极限平衡方法仅适用于线性强度准则下边坡稳定性分析。此外,预应力锚索作为一种主动防护措施,可极大地即时提高边坡稳定性而被广泛应用于中、大型边坡工程加固。然而,在应力松弛、蠕变效应以及腐蚀环境影响下预应力锚索加固边坡稳定性时效特征往往被忽视。由此,基于Morgenstern-Price(M-P)法,嵌入非线性Mohr-Coulomb(M-C)强度准则,并融入应力松弛与蠕变效应下锚索预应力损失模型以及腐蚀环境下锚索性能劣化模型,从而,建立非线性强度准则下预应力锚索加固边坡安全系数时程表达式。进一步,为了解决非线性强度准则下隐式嵌套公式难以求解的问题,归零化条间法向力初始值,并应用迭代循环求解策略,在引入循环终止允许误差判别条件后,可实现边坡稳定性理论真实结果的逼近求解。经过后续算例对比分析,验证了所提方法的可行性和合理性,与此同时,还研究了不同预应力损失速率和不同锈蚀环境下预应力锚索加固边坡稳定性的时效变化规律。 展开更多
关键词 边坡 极限平衡m-p 非线性m-C强度准则 预应力锚索加固 时效稳定性
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水平受荷桩“p-y+M-θ”分析方法
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作者 王立忠 赖踊卿 +1 位作者 洪义 张友虎 《岩土工程学报》 EI CAS CSCD 北大核心 2024年第5期905-918,共14页
中国近海海上风电机组开发建设中,大直径单桩基础形式使用占比超70%。现行p-y曲线设计方法主要适用于小直径柔性桩,对大直径单桩侧向及桩底受荷描述能力不足,导致其严重低估刚柔性桩和刚性桩(分别常用于中国和欧洲的近海风电工程)的变... 中国近海海上风电机组开发建设中,大直径单桩基础形式使用占比超70%。现行p-y曲线设计方法主要适用于小直径柔性桩,对大直径单桩侧向及桩底受荷描述能力不足,导致其严重低估刚柔性桩和刚性桩(分别常用于中国和欧洲的近海风电工程)的变形和承载能力,过于保守的设计给海上风电降本带来挑战。为此建立了能以统一的方式预测柔性、刚柔性和刚性单桩水平单调受荷响应的“p-y+M-θ”模型,并将该模型推广到循环荷载下单桩的响应分析。通过与相关试验结果比对发现,“p-y+M-θ”模型能较为准确地预测桩基水平加载响应。力图为水平受荷单桩工程设计提供简洁而可行的响应分析方法。 展开更多
关键词 软黏土 p-y%pLUS%m-θ”模型 水平受荷桩循环加载 试验结果对比
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狂犬病病毒GX074株P-M^(S20F)突变体构建及其生长特性鉴定
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作者 彭璟 李文芳 +3 位作者 陆丽莹 韦显凯 李晓宁 罗廷荣 《南方农业学报》 CAS CSCD 北大核心 2024年第1期253-262,共10页
【目的】明确狂犬病病毒(RABV)强毒株GX074的P蛋白和M蛋白第20位苯丙氨酸(Phe)替换至弱毒株r RC-HL的重组突变体在宿主细胞内的生长特性,为P蛋白和M蛋白转录复制机理研究提供理论依据。【方法】运用反向遗传技术以强毒株GX074的M蛋白第2... 【目的】明确狂犬病病毒(RABV)强毒株GX074的P蛋白和M蛋白第20位苯丙氨酸(Phe)替换至弱毒株r RC-HL的重组突变体在宿主细胞内的生长特性,为P蛋白和M蛋白转录复制机理研究提供理论依据。【方法】运用反向遗传技术以强毒株GX074的M蛋白第20位Phe替换弱毒株r RC-HL(GX074P)的M蛋白第20位丝氨酸(Ser),构建r RC-HL(GX074P-M^(S20F))突变体感染性c DNA克隆并拯救病毒。以重组突变体感染BSR/T7-9细胞,进行多步生长曲线测定,比较重组突变体与亲本毒株的生长能力,采用Western blotting检测N蛋白、P蛋白和M蛋白相对表达水平,利用实时荧光定量PCR检测N基因、P基因和M基因的相对表达量。【结果】经RT-PCR和测序鉴定,拯救的突变体r RC-HL(GX074P-M^(S20F))M蛋白第20位Ser成功替换为Phe。多步生长曲线测定结果显示,构建的重组突变体在感染24、48、72和96 h后,病毒滴度均高于亲本弱毒株r RC-HL和对照弱毒株r RC-HL(GX074PM1),平均约为亲本弱毒株r RC-HL的10倍。在蛋白表达水平上,r RC-HL(GX074P-M^(S20F))毒株在感染48 h后,N蛋白和M蛋白相对表达水平均极显著高于亲本弱毒株r RC-HL(P<0.01),说明强毒株GX074的P蛋白联合M蛋白第20位Phe替换至弱毒株r RC-HL后,增加了突变体N蛋白和M蛋白表达。感染24和48 h后,r RC-HL(GX074P-M^(S20F))毒株N基因、P基因和M基因的相对表达量均高于亲本弱毒株r RC-HL和对照弱毒株r RC-HL(GX074PM1)。【结论】强毒株GX074的M蛋白第20位Phe替换可提高病毒的增殖能力,同时增强病毒的复制与转录能力,M蛋白第20位Phe可能是影响病毒复制和转录的关键位点。 展开更多
关键词 狂犬病病毒(RABV) p蛋白 m蛋白 生长特性 反向遗传
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P/M和W/C对磷酸镁水泥强度的影响分析
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作者 刘欣 赵友帅 +6 位作者 唐宇晗 李帅 张海霞 赵鑫 张晓平 辛自洁 岳雪涛 《中国港湾建设》 2024年第3期39-43,70,共6页
为探究磷镁比(P/M)及水灰比(W/C)对磷酸镁水泥强度的影响和作用机理,对其力学性能进行测试,并结合XRD、SEM和FT-IR等测试手段对其物相组成及微观形貌进行表征和分析。研究结果表明:W/C=0.15时,磷酸二氢钾掺量的降低会使磷酸镁水泥的各... 为探究磷镁比(P/M)及水灰比(W/C)对磷酸镁水泥强度的影响和作用机理,对其力学性能进行测试,并结合XRD、SEM和FT-IR等测试手段对其物相组成及微观形貌进行表征和分析。研究结果表明:W/C=0.15时,磷酸二氢钾掺量的降低会使磷酸镁水泥的各龄期抗压强度增强,P/M=1:4时其3 h强度超过30 MPa,而当掺量过高时,3 h强度低于20 MPa,其产物MgKPO_(4)·6H_(2)O(K-struvite)的生成量减少且试件存在开裂区域;W/C=0.25时,减少MgO的掺量可以提高磷酸镁水泥的强度,P/M=1:1.5时,3 h的抗压强度接近30 MPa,磷酸镁水泥的水化产物K-struvite形貌结晶完好且排列紧密。 展开更多
关键词 p/m W/C 磷酸镁水泥 抗压强度 水化产物
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Cooling γ′ precipitation behavior and strengthening in powder metallurgy su-peralloy FGH4096 被引量:3
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作者 TIAN Gaofeng JIA Chengchang WEN Yin LIU Guoquan HU Benfu 《Rare Metals》 SCIE EI CAS CSCD 2008年第4期410-417,共8页
Two cooling schemes (continuous cooling and interrupted cooling tests) were applied to investigate the cooling γ precipitation behavior in powder metallurgy superalloy FGH4096. The effect of cooling rate on cooling... Two cooling schemes (continuous cooling and interrupted cooling tests) were applied to investigate the cooling γ precipitation behavior in powder metallurgy superalloy FGH4096. The effect of cooling rate on cooling γ precipitation and the development of γ precipitates during cooling process were involved in this study. The ultimate tensile strength (ErrS) of the specimens in various cooling circumstances was tested. The experiential equations were obtained between the average sizes of secondary and tertiary γ precipitates, the strength, and cooling rate. The results show that they are inversely correlated with the cooling rate as well as the grain boundary changes from serrated to straight, the shape of secondary γ precipitates changes from irregular cuboidal to spherical, while the formed tertiary γ precipitates are always spherical. The interrupted cooling tests show that the average size of secondary γ precipitates increases as a linear function of interrupt temperature for a fixed cooling rate of 24℃/min. The strength first decreases and then increases against interrupt temperature, which is fundamentally caused by the multistage nucleation of γ precipitates during cooling process. 展开更多
关键词 nickel-base superalloy powder metallurgy p/m γ precipitates cooling rate heat treatment
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子痫前期孕妇微小RNA-210-5p和整合素αM表达水平及检测意义
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作者 郭瑜 周永红 +3 位作者 魏丹 张冰 梁洭荥 何荣霞 《陕西医学杂志》 CAS 2024年第11期1552-1557,共6页
目的:探讨子痫前期孕妇微小RNA-210-5p(miR-210-5p)和整合素αM(ITGAM)的表达水平及检测意义。方法:选取40例子痫前期孕妇为病例组,并根据病情严重程度将病例组分为PE组(19例)和重度PE组(21例)。另选取同期在本院就诊的健康孕妇40例为... 目的:探讨子痫前期孕妇微小RNA-210-5p(miR-210-5p)和整合素αM(ITGAM)的表达水平及检测意义。方法:选取40例子痫前期孕妇为病例组,并根据病情严重程度将病例组分为PE组(19例)和重度PE组(21例)。另选取同期在本院就诊的健康孕妇40例为对照组。分别采用RT-qPCR和免疫荧光法检测胎盘组织miR-210-5p和ITGAM表达。采用流式细胞术检测外周血单核细胞表面ITGAM表达。比较病例组与对照组临床资料以及ITGAM和miR-210-5p表达水平。比较不同病情严重程度PE患者ITGAM和miR-210-5p表达水平。分析miR-210-5p、ITGAM表达水平与PE患者临床资料的相关性。结果:病例组孕前体重指数(BMI)、收缩压、舒张压、尿酸(UA)、肌酐(Cr)、天门冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)、乳酸脱氢酶(LDH)及平均血小板体积(MPV)高于对照组,分娩孕周、新生儿体重及白蛋白(ALB)低于对照组(均P<0.05)。与对照组比较,病例组外周血单核细胞表面以及胎盘组织ITGAM表达水平降低,胎盘组织miR-210-5p表达水平升高(均P<0.05)。与PE组比较,重度PE组胎盘组织ITGAM表达水平降低,miR-210-5p表达水平升高(均P<0.05)。胎盘组织miR-210-5p与ITGAM表达水平呈负相关(P<0.05)。胎盘组织miR-210-5p表达水平与患者收缩压、舒张压、AST、ALT、LDH及24 h尿蛋白定量呈正相关,与分娩孕周、新生儿体重及白蛋白水平呈负相关(均P<0.05)。胎盘组织ITGAM表达水平与患者收缩压、舒张压、AST、ALT、LDH及24 h尿蛋白定量呈负相关,与分娩孕周、新生儿体重及白蛋白水平呈正相关(均P<0.05)。外周血单核细胞表面ITGAM表达水平与患者LDH及24 h尿蛋白定量呈负相关,与白蛋白水平呈正相关(均P<0.05)。结论:PE孕妇胎盘组织miR-210-5p表达水平升高,外周血单核细胞表面及胎盘组织ITGAM表达水平均降低,且二者与PE的病情严重程度有关。 展开更多
关键词 子痫前期 微小RNA-210-5p 整合素αm 胎盘 外周血 相关性
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Microstructural evolution in a powder metallurgical Ti-7Mo alloy with continuous oxygen gradient 被引量:2
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作者 陈智星 刘彬 +2 位作者 刘咏 曾凡沛 卢金忠 《Journal of Central South University》 SCIE EI CAS CSCD 2016年第3期508-514,共7页
A titanium alloy containing continuous oxygen gradient was prepared by powder metallurgy(P/M) and the composition–property relationship was studied on a single sample. The alloy was sintered with layered powder of di... A titanium alloy containing continuous oxygen gradient was prepared by powder metallurgy(P/M) and the composition–property relationship was studied on a single sample. The alloy was sintered with layered powder of different oxygen contents via vacuum sintering and spark plasma sintering(SPS), respectively. After subsequent heat treatments, high-throughput characterizations of the microstructures and mechanical properties by localized measurements were conducted. The Ti-7% Mo(molar fraction) alloy with an oxygen content ranging from 1.3×10^(-3) to 6.2×10^(-5)(mass fraction) was obtained, and the effects of oxygen on the microstructural evolution and mechanical properties were studied. The results show that SPS is an effective way for fabricating fully dense Ti alloy with a compositional gradient. The average width of α′ phase coarsens with the increase of the content of oxygen. The content of α″ martensitic phase also increases with the content of oxygen. At oxygen contents of 3×10^(-3) and 4×10^(-3)(mass fraction), the Ti alloys present the lowest microhardness and the lowest elastic modulus, respectively. The results also indicate that the martensitic phases actually decrease the hardness of Ti-7Mo alloy, and oxygen effectively hardens the alloy by solid solution strengthening. Therefore, the high-throughput characterization on a microstructure with a gradient content of oxygen is an effective method for rapidly evaluating the composition–property relationship of titanium alloys. 展开更多
关键词 titanium alloys oxygen martensitic transformation high-throughput method powder metallurgy p/m mechanical properties
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miR-26a-5p调控PTEN/PI3K/Akt信号通路对高糖诱导视网膜Müller细胞活化及凋亡的影响
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作者 唐德荣 杨雨雯 +1 位作者 石蕊 刘丹丹 《西安交通大学学报(医学版)》 CAS CSCD 北大核心 2024年第5期705-711,共7页
目的检测微小RNA-26a-5p(microRNA-26a-5p,miR-26a-5p)对PTEN/PI3K/Akt信号通路及高糖刺激的视网膜Müller细胞凋亡的影响,探讨糖尿病视网膜神经损伤的潜在机制。方法采用不同浓度的葡萄糖刺激视网膜Müller细胞构建糖尿病视网... 目的检测微小RNA-26a-5p(microRNA-26a-5p,miR-26a-5p)对PTEN/PI3K/Akt信号通路及高糖刺激的视网膜Müller细胞凋亡的影响,探讨糖尿病视网膜神经损伤的潜在机制。方法采用不同浓度的葡萄糖刺激视网膜Müller细胞构建糖尿病视网膜神经损伤模型,采用CCK-8及流式细胞仪观察细胞增殖及凋亡情况,细胞转染过表达miR-26a-5p模拟物,Real-time PCR检测miR-26a-5p、PTEN、PI3K、Akt的表达情况,ELISA测定细胞上清液中IL-1β及IL-6的水平,采用Graphpad 8.0软件处理数据。结果高糖刺激视网膜Müller细胞生长活跃,与对照组相比,50 mmol/L高糖刺激Müller细胞活力在12 h、24 h时逐渐增加,48 h时活力减弱,细胞凋亡增加,组间差异有统计学意义(P<0.05)。高糖刺激后视网膜Müller细胞中miR-26a-5p水平下降,PTEN的表达显著升高,PI3K及Akt水平下降,IL-1β及IL-6的水平明显升高,过表达miR-26a-5p后,PTEN水平降低,PI3K/Akt及炎性因子降低,细胞凋亡减少(P<0.01)。结论miR-26a-5p通过调控PTEN/PI3K/Akt的表达,影响炎症因子释放,减轻高糖诱导的视网膜Müller细胞凋亡。 展开更多
关键词 视网膜mÜLLER细胞 微小RNA-26a-5p(miR-26a-5p) pTEN/pI3K/Akt 炎症 糖尿病视网膜病变
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Homer1a reduces inflammatory response after retinal ischemia/reperfusion injury 被引量:1
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作者 Yanan Dou Xiaowei Fei +7 位作者 Xin He Yu Huan Jialiang Wei Xiuquan Wu Weihao Lyu Zhou Fei Xia Li Fei Fei 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第7期1608-1617,共10页
Elevated intraocular pressure(IOP)is one of the causes of retinal ischemia/reperfusion injury,which results in NRP3 inflammasome activation and leads to visual damage.Homerla is repo rted to play a protective role in ... Elevated intraocular pressure(IOP)is one of the causes of retinal ischemia/reperfusion injury,which results in NRP3 inflammasome activation and leads to visual damage.Homerla is repo rted to play a protective role in neuroinflammation in the cerebrum.However,the effects of Homerla on NLRP3inflammasomes in retinal ischemia/reperfusion injury caused by elevated IOP remain unknown.In our study,animal models we re constructed using C57BL/6J and Homer1^(flox/-)/Homerla^(+/-)/Nestin-Cre^(+/-)mice with elevated IOP-induced retinal ischemia/repe rfusion injury.For in vitro expe riments,the oxygen-glucose deprivation/repe rfusion injury model was constructed with M uller cells.We found that Homerla ove rexpression amelio rated the decreases in retinal thickness and Muller cell viability after ischemia/reperfusion injury.Furthermore,Homerla knockdown promoted NF-κB P65^(Ser536)activation via caspase-8,NF-κB P65 nuclear translocation,NLRP3 inflammasome formation,and the production and processing of interleukin-1βand inte rleukin-18.The opposite results we re observed with Homerla ove rexpression.Finally,the combined administration of Homerla protein and JSH-23 significantly inhibited the reduction in retinal thickness in Homer1^(flox/-)Homer1a^(+/-)/Nestin-Cre^(+/-)mice and apoptosis in M uller cells after ischemia/reperfusion injury.Taken together,these studies demonstrate that Homer1a exerts protective effects on retinal tissue and M uller cells via the caspase-8/NF-KB P65/NLRP3 pathway after I/R injury. 展开更多
关键词 CASpASE-8 Homer1a INTERLEUKIN-18 INTERLEUKIN-1Β intraocular pressure ischemia/reperfusion injury JSH-23 müller cells NLRp3 nuclear factor-kB p65 RETINA
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一类带p-Laplace算子的非线性二阶m点共振边值问题解的存在性
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作者 刘美玉 马锦然 裴明鹤 《北华大学学报(自然科学版)》 CAS 2024年第1期1-7,共7页
基于拓扑横截方法连同障碍带技巧,得到一类带p-Laplace算子的非线性二阶m点共振边值问题解的新的存在性结果,并给出应用举例。
关键词 p-LApLACE算子 m点共振边值问题 存在性 拓扑横截方法 障碍带技巧
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CRITICAL ISSUES OF POWDER METALLURGY TURBINE DISKS 被引量:1
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作者 K.M. Chang(Department of Mechanical and Aerospace Engineering,West Virginia University, P.O. Box 6160, Morgantown,WV 26506, USA 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 1996年第6期467-471,共5页
P/M superalloy disks obtain their final strength by appropriate heat treatments; the maximum attainable strength depends on the rapid cooling rate from the solution annealing. A rapid quench of a large disk forging ca... P/M superalloy disks obtain their final strength by appropriate heat treatments; the maximum attainable strength depends on the rapid cooling rate from the solution annealing. A rapid quench of a large disk forging can cause two problems, surface cracking and shape distortion.In the past,many attempts employ the finite element code to model and to predict temperature evolution and induced stress distribution in a large turbine disk. The major difficulty was the correct description of alloy behavior; particularly the thermomechanical properties and the failure criteria of material during the cooling. High temperature fatigue resistance is always the key requirement for disk materials. New methodology of residual life management emphasizes the initiation as well as the propagation of the cracks developed under the service conditions. One of major challenges to P/M superalloys is the time-dependent behavior of fatigue cracking, which relates to the well-known SAGBO (stress-assisted grain boundary oxidation) phenomenon.A great effort has been done to understand the micro-mechanism of time-dependent fatigue crack propagation resulted in the second generation of P/M superalloys. Further improvement on temperature capability of disk alloys at rim area may lead to the idea of dual-property disks.Different grain structures at different portions of a large disk are possible,as the property requirements for different locations are different. This goal is achievable if the thermal history at specific disk locations can be controlled to develop desirable microstructures and properties.Some suggestions on the future direction of research efforts will be discused. 展开更多
关键词 superalloy disk powder metallurgy (p/m) quench cracking fatigue crack propagation SAGBO (stress-assisted grain boundary oxidation) dual-property disk grain size
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Understanding the Activity Performance of Comets 38P/Stephan-Oterma,64P/Swift-Gehrels and C/2017 M4(ATLAS)through Broadband Photometric Observations
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作者 Xuan Zhang Jin-Zhong Liu Le-Tian Wang 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2024年第8期147-156,共10页
In this work,we report observations of three comets:38P/Stephan-Oterma,64P/Swift-Gehrels,and C/2017 M4(ATLAS),conducted with the Nanshan one-meter wide-field telescope in 2018 August and November,and 2019January.We ex... In this work,we report observations of three comets:38P/Stephan-Oterma,64P/Swift-Gehrels,and C/2017 M4(ATLAS),conducted with the Nanshan one-meter wide-field telescope in 2018 August and November,and 2019January.We extracted morphological features through image enhancement techniques and calculated the dust activity parameter,Afρ,along with dust mass loss rates and coma color indices using broadband photometric data.Our morphological analysis uncovered a spectrum of dust characteristics among the observed comets,ranging from a significant twisted structure in comet 38P/Stephan-Oterma’s coma to the regular coma envelope surrounding comet 64P/Swift-Gehrels.The Afρvalues varied between 148.8±0.3 cm for 64P/Swift-Gehrels and1118.5±6.2 cm for C/2017 M4(ATLAS)(measured within a reference aperture radius ofρ=6″),indicating a range from moderate to high activity levels.Dust mass loss rates were estimated from 328.1 kg s^(-1)for comet 64P/Swift-Gehrels to 1395.5 kg s^(-1)for comet C/2017 M4(ATLAS).The color indices of comets 38P/Stephan-Oterma and C/2017 M4(ATLAS)closely resemble the average colors of active short-period comets and active longperiod comets,respectively.In contrast,64P/Swift-Gehrels exhibits a significantly bluer hue than typical Jupiter family comets. 展开更多
关键词 comets general-comets individual(38p/Stephan-Oterma 64p/Swift-Gehrels C/2017 m4(ATLAS))-techniques pHOTOmETRIC
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Virtual Keyboard:A Real-Time Hand Gesture Recognition-Based Character Input System Using LSTM and Mediapipe Holistic
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作者 Bijon Mallik Md Abdur Rahim +2 位作者 Abu Saleh Musa Miah Keun Soo Yun Jungpil Shin 《Computer Systems Science & Engineering》 2024年第2期555-570,共16页
In the digital age,non-touch communication technologies are reshaping human-device interactions and raising security concerns.A major challenge in current technology is the misinterpretation of gestures by sensors and... In the digital age,non-touch communication technologies are reshaping human-device interactions and raising security concerns.A major challenge in current technology is the misinterpretation of gestures by sensors and cameras,often caused by environmental factors.This issue has spurred the need for advanced data processing methods to achieve more accurate gesture recognition and predictions.Our study presents a novel virtual keyboard allowing character input via distinct hand gestures,focusing on two key aspects:hand gesture recognition and character input mechanisms.We developed a novel model with LSTM and fully connected layers for enhanced sequential data processing and hand gesture recognition.We also integrated CNN,max-pooling,and dropout layers for improved spatial feature extraction.This model architecture processes both temporal and spatial aspects of hand gestures,using LSTM to extract complex patterns from frame sequences for a comprehensive understanding of input data.Our unique dataset,essential for training the model,includes 1,662 landmarks from dynamic hand gestures,33 postures,and 468 face landmarks,all captured in real-time using advanced pose estimation.The model demonstrated high accuracy,achieving 98.52%in hand gesture recognition and over 97%in character input across different scenarios.Its excellent performance in real-time testing underlines its practicality and effectiveness,marking a significant advancement in enhancing human-device interactions in the digital age. 展开更多
关键词 Hand gesture recognition m.p.holistic open CV virtual keyboard LSTm human-computer interaction
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具有随机检修-策略M/G/1系统队长的瞬态与稳态分析
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作者 李占宇 唐应辉 《工程数学学报》 CSCD 北大核心 2024年第6期1155-1169,共15页
研究一个具有随机检修<p,Y>-策略的M/G/1排队系统,当系统变空时,以概率p(0≤p≤1)对系统进行检修,且检修时间是具有任意分布的随机变量。首先,分析了队长的嵌入马尔可夫链,得到了其稳态分布的概率母函数。其次,讨论了在任意时刻t... 研究一个具有随机检修<p,Y>-策略的M/G/1排队系统,当系统变空时,以概率p(0≤p≤1)对系统进行检修,且检修时间是具有任意分布的随机变量。首先,分析了队长的嵌入马尔可夫链,得到了其稳态分布的概率母函数。其次,讨论了在任意时刻t队长的瞬态分布,得到了队长的瞬态分布关于时间t的拉普拉斯变换表达式。在队长瞬态分析的基础上,应用洛必达法则,通过直接计算获得了在任意时刻队长的稳态分布的递推式,给出了稳态队长的随机分解结构。最后,建立了系统的费用模型,并通过数值实例得到了使系统费用最少的最优检修策略。 展开更多
关键词 m/G/1排队 随机检修<p Y>-策略 全概率分解 队长分布 最优检修策略
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Simulating the Dynamics of Bimetallic Clusters Deposited onto a Surface Using Molecular Dynamics
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作者 Akbarali Rasulov Nodirbek Ibrokhimov +1 位作者 Jaxongir Khodjimatov Azamatjon Tukhtasinov 《Journal of Applied Mathematics and Physics》 2024年第8期2820-2828,共9页
This paper examines the interface development between a single crystalline Ag matrix and core-shell AgnCom nanoclusters that have been deposited with energies varying between 0.25 eV and 1.5 eV per atom using computer... This paper examines the interface development between a single crystalline Ag matrix and core-shell AgnCom nanoclusters that have been deposited with energies varying between 0.25 eV and 1.5 eV per atom using computer modeling techniques. Clusters undergo deformation as a result of the slowing down;they may also become epitaxial with the substrate and maintain their core-shell structure. A detailed analysis of the effects of the cluster-surface interaction is conducted over a realistic size and energy range, and a model is created to show how clusters accumulate. It is discovered that both the silver shells and the cobalt cluster cores exhibit limited epitaxy with the substrate, and that the contact produced is only a few atomic layers thick. The effect is higher for Ag shells than for Co cores, and it is not very energy dependent. 展开更多
关键词 CLUSTER Slowing Down LOW-ENERGY molecular Dynamics metrоpоlis mоnte Cаrlо Bi-metallic
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On Some Mathematical Connections between the Cyclic Universe, Inflationary Universe, p-Adic Inflation, p-Adic Cosmology and Various Sectors of Number Theory
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作者 Michele Nardelli 《Journal of Modern Physics》 2024年第11期1869-1958,共90页
This paper is a review, a thesis, of some interesting results that have been obtained in various research concerning the “brane collisions in string and M-theory” (Cyclic Universe), p-adic inflation and p-adic cosmo... This paper is a review, a thesis, of some interesting results that have been obtained in various research concerning the “brane collisions in string and M-theory” (Cyclic Universe), p-adic inflation and p-adic cosmology. In Section 2, we have described some equations concerning cosmic evolution in a Cyclic Universe. In Section 3, we have described some equations concerning the cosmological perturbations in a Big Crunch/Big Bang space-time, the M-theory model of a Big Crunch/Big Bang transition and some equations concerning the solution of a braneworld Big Crunch/Big Bang Cosmology. In Section 4, we have described some equations concerning the generating ekpyrotic curvature perturbations before the Big Bang, some equations concerning the effective five-dimensional theory of the strongly coupled heterotic string as a gauged version of N=1five-dimensional supergravity with four-dimensional boundaries, and some equations concerning the colliding branes and the origin of the Hot Big Bang. In Section 5, we have described some equations regarding the “null energy condition” violation concerning the inflationary models and some equations concerning the evolution to a smooth universe in an ekpyrotic contracting phase with w>1. In Section 6, we have described some equations concerning the approximate inflationary solutions rolling away from the unstable maximum of p-adic string theory. In Section 7, we have described various equations concerning the p-adic minisuperspace model, zeta strings, zeta nonlocal scalar fields and p-adic and adelic quantum cosmology. In Section 8, we have shown various and interesting mathematical connections between some equations concerning the p-adic inflation, the p-adic quantum cosmology, the zeta strings and the brane collisions in string and M-theory. Furthermore, in each section, we have shown the mathematical connections with various sectors of Number Theory, principally the Ramanujan’s modular equations, the Aurea Ratio and the Fibonacci’s numbers. 展开更多
关键词 String Theory m-THEORY Cyclic Cosmology p-Adic and Adelic Analysis Number Theory Ramanujan’s modular Equations
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我国四株狂犬病毒M和P基因序列分析和所编码蛋白的分析 被引量:9
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作者 张强 唐青 +2 位作者 李浩 王环宇 梁国栋 《病毒学报》 CAS CSCD 北大核心 2007年第2期115-120,共6页
为了解我国狂犬病毒M、P基因序列和结构特点,用RT-PCR方法获得目的基因片段,测定核苷酸序列后,计算机分析核苷酸和氨基酸序列及其功能区位点结构。结果显示四株病毒M基因核苷酸和氨基酸序列同源性分别为83.9%~99.5%和93.1%~99%,四株... 为了解我国狂犬病毒M、P基因序列和结构特点,用RT-PCR方法获得目的基因片段,测定核苷酸序列后,计算机分析核苷酸和氨基酸序列及其功能区位点结构。结果显示四株病毒M基因核苷酸和氨基酸序列同源性分别为83.9%~99.5%和93.1%~99%,四株狂犬病毒M蛋白上调节病毒RNA转录和复制功能的第58位氨基酸残基均为谷氨酰胺残基(E),与特异性细胞蛋白WW区域作用的PPxY结构序列均为PPEY保守序列;四株病毒P基因核苷酸和氨基酸序列同源性分别为83.6%~99.8%和87.2%~99%,P蛋白与胞浆动力蛋白轻链LC8相互作用的序列位于143~148位氨基酸残基,均为DKSTQT,四株病毒P基因与L蛋白、N蛋白作用位点序列显示未发生影响其生物学功能的变异。研究结果证实了这两种蛋白结构在病毒致病性中起重要作用的推论。 展开更多
关键词 狂犬病毒 m基因 p基因 测序分析 编码蛋白比较
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m(P)/m(M)比值对磷酸镁水泥性能影响及作用机理分析 被引量:8
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作者 薛明 汪宏涛 +1 位作者 肖晓 曹巨辉 《功能材料》 EI CAS CSCD 北大核心 2015年第23期23090-23095,共6页
研究了原材料磷酸二氢铵(P)与氧化镁(M)的质量比值对磷酸镁水泥抗压强度和凝结时间的影响,通过XRD、扫描电镜和能谱检测分析了该比值影响的作用机理.研究发现,材料体系是由大量未反应的氧化镁颗粒被水化产物胶结而形成的强度体系,... 研究了原材料磷酸二氢铵(P)与氧化镁(M)的质量比值对磷酸镁水泥抗压强度和凝结时间的影响,通过XRD、扫描电镜和能谱检测分析了该比值影响的作用机理.研究发现,材料体系是由大量未反应的氧化镁颗粒被水化产物胶结而形成的强度体系,氧化镁对水化反应速率和强度发展至关重要;水化产物主要为磷酸铵镁和磷酸镁类化合物,其组成及晶体形貌结构受m (P)/m (M)比值影响较大,当m (P)/m (M)比值在1/4-1/5时,水化产物晶体微观形貌结构密实,材料强度较高. 展开更多
关键词 m(p)/m(m)比值 磷酸镁水泥(mpC) 性能 机理
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不同粒度的镍基高温合金粉末及其对P/M成形件组织性能影响的研究 被引量:7
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作者 张莹 张义文 +2 位作者 张凤戈 陶宇 冯涤 《兵器材料科学与工程》 CAS CSCD 2002年第6期34-36,40,共4页
研究了用PREP法制造的不同粒度范围的FGH95合金粉末的物理特征及其HIP成形件的组织性能。结果表明 ,使用 5 0~ 10 0 μm和 5 0~ 15 0 μm粒度范围的粉末是降低成本、简化工序、保证产品质量的最佳选择。
关键词 粒度 镍基高温合金粉末 p/m成形件 组织性能 pGH95合金
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利用SEBAL模型与P-M公式估算乌裕尔河下游地表蒸散 被引量:4
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作者 曾丽红 宋开山 +2 位作者 张柏 王宗明 杜嘉 《干旱地区农业研究》 CSCD 北大核心 2009年第5期216-224,234,共10页
先通过SEBAL模型估算了乌裕尔河下游沼泽旱地交错区1992年7月9日、1994年7月15日、1995年7月18日、1999年7月13日4个时相的日蒸散量,并通过P-M公式与作物系数进行时间尺度扩展得到了这4个时相所处月份的蒸散量,最后对日蒸散量、作物系... 先通过SEBAL模型估算了乌裕尔河下游沼泽旱地交错区1992年7月9日、1994年7月15日、1995年7月18日、1999年7月13日4个时相的日蒸散量,并通过P-M公式与作物系数进行时间尺度扩展得到了这4个时相所处月份的蒸散量,最后对日蒸散量、作物系数、月蒸散量的特征及其影响因素进行分析。结果表明:日蒸散量的频率分布图呈双峰结构,分别体现了旱地的蒸散特征、湿地与水体的蒸散特征;平均日蒸散量依照1994-07-15、1999-07-13、1995-07-18、1992-07-09的顺序依次降低;时相1994-07-15的平均日蒸散量与平均作物系数最高;通过逐步回归分析发现日平均风速、日照时数、日最低气温对参考作物日蒸散量的影响较为明显。 展开更多
关键词 遥感 蒸散 SEBAL pm公式 作物系数
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