In this paper, we study some properties of n-strongly Gorenstein projective,injective and flat modules, and discuss some connections between n-strongly Gorenstein injective, projective and flat modules. Some applicati...In this paper, we study some properties of n-strongly Gorenstein projective,injective and flat modules, and discuss some connections between n-strongly Gorenstein injective, projective and flat modules. Some applications are given.展开更多
In this paper, we mainly investigate some properties of strongly n-Gorenstein projective, injective and flat modules under the extension of rings, which mainly including excellent extensions, morita equivalences, poly...In this paper, we mainly investigate some properties of strongly n-Gorenstein projective, injective and flat modules under the extension of rings, which mainly including excellent extensions, morita equivalences, polynomial extensions and localizations.展开更多
In this article, we introduce and study the concept of n-Gorenstein injective (resp., n-Gorenstein flat) modules as a nontrivial generalization of Gorenstein injective (resp., Gorenstein flat) modules. We invest...In this article, we introduce and study the concept of n-Gorenstein injective (resp., n-Gorenstein flat) modules as a nontrivial generalization of Gorenstein injective (resp., Gorenstein flat) modules. We investigate the properties of these modules in various ways. For example, we show that the class of n-Gorenstein injective (resp., n -Gorenstein flat) modules is closed under direct sums and direct products for n ≥ 2. To this end, we first introduce and study the notions of n-injective modules and n-flat modules.展开更多
A left ideal I of a ring R is small in case for every proper left ideal K of R, K + I ≠R. A ring R is called left PS-coherent if every principally small left ideal Ra is finitely presented. We develop, in this paper...A left ideal I of a ring R is small in case for every proper left ideal K of R, K + I ≠R. A ring R is called left PS-coherent if every principally small left ideal Ra is finitely presented. We develop, in this paper, PS-coherent rings as a generalization of P-coherent rings and J-coherent rings. To characterize PS-coherent rings, we first introduce PS-injective and PS-flat modules, and discuss the relation between them over some spacial rings. Some properties of left PS-coherent rings are also studied.展开更多
We first introduce the concepts of absolutely E-pure modules and E-pure split modules. Then, we characterize the IF rings in terms of absolutely E-pure modules. The E-pure split modules are also characterized.
AIM: To describe the long term follow-up of kidney allograft recipients receiving ketoconazole with calcineurin inhibitors(CNI) alone or combined with everolimus. METHODS: This is an open-label, prospective observatio...AIM: To describe the long term follow-up of kidney allograft recipients receiving ketoconazole with calcineurin inhibitors(CNI) alone or combined with everolimus. METHODS: This is an open-label, prospective observational clinical trial in low immunologic risk patients who, after signing an Institutional Review Board approved consent form, were included in one of two groups. The first one(n = 59) received everolimus(target blood level, 3-8 ng/m L) and the other(n = 114) azathioprine 2 mg/kg per day or mycophenolate mofetyl(MMF) 2 g/d. Both groups also received tapering steroids, the cytochrome P-450 3A4(CYP3A4) modulator, ketoconazole 50-100 mg/d, and cyclosporine with C0 targets in the everolimus group of 200-250 ng/mL in 1 mo, 100-125 ng/m L in 2 mo, and 50-65 ng/m L thereafter, and in the azathioprine or MMF group of 250-300 ng/mL in 1 mo, 200-250 ng/mL in 2 mo, 180-200 ng/m L until 3-6 mo, and 100-125 ng/mL thereafter. Clinical visits were performed monthly the first year and quarterly thereafter by treating physicians and all data was extracted by the investigators.RESULTS: The clinical characteristics of these two cohorts were similar. During the follow up(66 + 31 mo), both groups showed comparable clinical courses, but the biopsy proven acute rejection rate during the full follow-up period seemed to be lower in the everolimus group(20% vs 36%; P = 0.04). The everolimus group did not show a higher surgical complication rate thanthe other group. By the end of the follow-up period, the everolimus group tended to show a higher glomerular filtration rate. Nevertheless, we found no evidence of a consistent negative slope of the temporal allograft function estimated by the modification of the diet in renal disease formula in any of both groups. At 6 years of follow-up, the uncensored and death-censored graft survivals were 91% and 93%, and 91% and 83% in the everolimus plus cyclosporine, and cyclosporine alone groups, respectively. The addition of ketoconazole saved 80% of cyclosporine and 56% of everolimus doses. CONCLUSION: Combining CYP3A4 modulators with CNI or mammalian target of rapamycin inhibitor, in low immunological risk kidney transplant recipients is feasible, effective, safe and affordable even in the long term.展开更多
In basic homological algebra, the flat and injective dimensions of modules play an important and fundamental role. In this paper, the closely related IFP-flat and IFP-injective dimensions are introduced and studied. W...In basic homological algebra, the flat and injective dimensions of modules play an important and fundamental role. In this paper, the closely related IFP-flat and IFP-injective dimensions are introduced and studied. We show that IFP-fd(M) = IFP-id(M+) and IFP-fd(M+)=IFP-id(M) for any R-module M over any ring R. Let :Z-In (resp., "Zgv,~) he the class of all left (resp., right) R-modules of IFP-injective (resp., IFP-flat) dimension at most n. We prove that every right R-module has an IFn- preenvelope, (IFn,IF⊥n) is a perfect cotorsion theory over any ring R, and for any ring R with IFP-id(RR) 〈 n, (IIn,II⊥n) is a perfect cotorsion theory. This generalizes and improves the earlier work (J. Algebra 242 (2001), 447-459). Finally, some applications are given.展开更多
In this paper, a flatly broadened and highly coherent supercontinuum generation by induced modulation instability in ANDi-PCF is proposed. The numerical results show that the bandwidth of supercontinuun can be increas...In this paper, a flatly broadened and highly coherent supercontinuum generation by induced modulation instability in ANDi-PCF is proposed. The numerical results show that the bandwidth of supercontinuun can be increased by increasing the modulation depth and the coherence property of supercontinuum can be improved with the optimal modulation frequency. A highly coherent supercontinuum with the 10 dB bandwidth of 1305 nm and the flatness of less than 10 dB can be obtained when seeding at the modulation depth of 0.3 and modulation frequency of 24 THz.展开更多
Amplitude modulation of near-wall turbulence by large-scale structures in the outer layer is investigated by direct numerical simulation of turbulent channel flows at Reynolds number Re= 540, 1000, 2000. The effect of...Amplitude modulation of near-wall turbulence by large-scale structures in the outer layer is investigated by direct numerical simulation of turbulent channel flows at Reynolds number Re= 540, 1000, 2000. The effect of modulation is obvious in the two-point cross-section correlation map, and the correlation coefficients increase significantly with the Reynolds number. The influence of modulation is reflected in the tail of the probability density function of the near-wall flow signals, which expands as the Reynolds number increases. The flatness factor provides a quantitative description of the high fluctuation events due to modulation. Vortical structures associated with modulation are revealed by conditionally averaging the flow field of the near-wall extreme events, providing a depiction of how the influence of the large-scale structures penetrate towards the near-wall region.展开更多
基金Supported by the National Natural Science Foundation of China(11361051) Supported by the Program for New Century Excellent the Talents in University(NCET-13-0957)
文摘In this paper, we study some properties of n-strongly Gorenstein projective,injective and flat modules, and discuss some connections between n-strongly Gorenstein injective, projective and flat modules. Some applications are given.
基金Supported by the NNSF of China(10901129)Supported by the SRFDP(20096203120001)
文摘In this paper, we mainly investigate some properties of strongly n-Gorenstein projective, injective and flat modules under the extension of rings, which mainly including excellent extensions, morita equivalences, polynomial extensions and localizations.
基金The NSF(11501451)of Chinathe Fundamental Research Funds(31920150038)for the Central Universities and XBMUYJRC(201406)
文摘In this article, we introduce and study the concept of n-Gorenstein injective (resp., n-Gorenstein flat) modules as a nontrivial generalization of Gorenstein injective (resp., Gorenstein flat) modules. We investigate the properties of these modules in various ways. For example, we show that the class of n-Gorenstein injective (resp., n -Gorenstein flat) modules is closed under direct sums and direct products for n ≥ 2. To this end, we first introduce and study the notions of n-injective modules and n-flat modules.
文摘A left ideal I of a ring R is small in case for every proper left ideal K of R, K + I ≠R. A ring R is called left PS-coherent if every principally small left ideal Ra is finitely presented. We develop, in this paper, PS-coherent rings as a generalization of P-coherent rings and J-coherent rings. To characterize PS-coherent rings, we first introduce PS-injective and PS-flat modules, and discuss the relation between them over some spacial rings. Some properties of left PS-coherent rings are also studied.
文摘We first introduce the concepts of absolutely E-pure modules and E-pure split modules. Then, we characterize the IF rings in terms of absolutely E-pure modules. The E-pure split modules are also characterized.
文摘AIM: To describe the long term follow-up of kidney allograft recipients receiving ketoconazole with calcineurin inhibitors(CNI) alone or combined with everolimus. METHODS: This is an open-label, prospective observational clinical trial in low immunologic risk patients who, after signing an Institutional Review Board approved consent form, were included in one of two groups. The first one(n = 59) received everolimus(target blood level, 3-8 ng/m L) and the other(n = 114) azathioprine 2 mg/kg per day or mycophenolate mofetyl(MMF) 2 g/d. Both groups also received tapering steroids, the cytochrome P-450 3A4(CYP3A4) modulator, ketoconazole 50-100 mg/d, and cyclosporine with C0 targets in the everolimus group of 200-250 ng/mL in 1 mo, 100-125 ng/m L in 2 mo, and 50-65 ng/m L thereafter, and in the azathioprine or MMF group of 250-300 ng/mL in 1 mo, 200-250 ng/mL in 2 mo, 180-200 ng/m L until 3-6 mo, and 100-125 ng/mL thereafter. Clinical visits were performed monthly the first year and quarterly thereafter by treating physicians and all data was extracted by the investigators.RESULTS: The clinical characteristics of these two cohorts were similar. During the follow up(66 + 31 mo), both groups showed comparable clinical courses, but the biopsy proven acute rejection rate during the full follow-up period seemed to be lower in the everolimus group(20% vs 36%; P = 0.04). The everolimus group did not show a higher surgical complication rate thanthe other group. By the end of the follow-up period, the everolimus group tended to show a higher glomerular filtration rate. Nevertheless, we found no evidence of a consistent negative slope of the temporal allograft function estimated by the modification of the diet in renal disease formula in any of both groups. At 6 years of follow-up, the uncensored and death-censored graft survivals were 91% and 93%, and 91% and 83% in the everolimus plus cyclosporine, and cyclosporine alone groups, respectively. The addition of ketoconazole saved 80% of cyclosporine and 56% of everolimus doses. CONCLUSION: Combining CYP3A4 modulators with CNI or mammalian target of rapamycin inhibitor, in low immunological risk kidney transplant recipients is feasible, effective, safe and affordable even in the long term.
基金supported by National Natural Science Foundation of China(10961021,11001222)
文摘In basic homological algebra, the flat and injective dimensions of modules play an important and fundamental role. In this paper, the closely related IFP-flat and IFP-injective dimensions are introduced and studied. We show that IFP-fd(M) = IFP-id(M+) and IFP-fd(M+)=IFP-id(M) for any R-module M over any ring R. Let :Z-In (resp., "Zgv,~) he the class of all left (resp., right) R-modules of IFP-injective (resp., IFP-flat) dimension at most n. We prove that every right R-module has an IFn- preenvelope, (IFn,IF⊥n) is a perfect cotorsion theory over any ring R, and for any ring R with IFP-id(RR) 〈 n, (IIn,II⊥n) is a perfect cotorsion theory. This generalizes and improves the earlier work (J. Algebra 242 (2001), 447-459). Finally, some applications are given.
文摘In this paper, a flatly broadened and highly coherent supercontinuum generation by induced modulation instability in ANDi-PCF is proposed. The numerical results show that the bandwidth of supercontinuun can be increased by increasing the modulation depth and the coherence property of supercontinuum can be improved with the optimal modulation frequency. A highly coherent supercontinuum with the 10 dB bandwidth of 1305 nm and the flatness of less than 10 dB can be obtained when seeding at the modulation depth of 0.3 and modulation frequency of 24 THz.
基金supported by the National Natural Science Foundation of China (Grants 11490551, 11472154, and 11322221)
文摘Amplitude modulation of near-wall turbulence by large-scale structures in the outer layer is investigated by direct numerical simulation of turbulent channel flows at Reynolds number Re= 540, 1000, 2000. The effect of modulation is obvious in the two-point cross-section correlation map, and the correlation coefficients increase significantly with the Reynolds number. The influence of modulation is reflected in the tail of the probability density function of the near-wall flow signals, which expands as the Reynolds number increases. The flatness factor provides a quantitative description of the high fluctuation events due to modulation. Vortical structures associated with modulation are revealed by conditionally averaging the flow field of the near-wall extreme events, providing a depiction of how the influence of the large-scale structures penetrate towards the near-wall region.