A new p-terphenyl derivative 1 was isolated from the fruiting bodies of Boletopsis grisea. Its structure was established as 2. 3-diacetoxy-4 ', 4 ', 5, 6-tetrahydroxy-p-terphenyl by spectroscopic and chemical ...A new p-terphenyl derivative 1 was isolated from the fruiting bodies of Boletopsis grisea. Its structure was established as 2. 3-diacetoxy-4 ', 4 ', 5, 6-tetrahydroxy-p-terphenyl by spectroscopic and chemical means.展开更多
We consider the photon emission statistical properties of a single molecule under pump-probe field driving, using the generating function method. The first- and second-order moments of statistical quantities are prese...We consider the photon emission statistical properties of a single molecule under pump-probe field driving, using the generating function method. The first- and second-order moments of statistical quantities are presented. Derived from the first-order moment, the line shapes are in good agreement with the experimental results. Derived from the second-order moment, Mandel＇s Q parameters show an obvious quantum effect of photon statistical distribution, i.e., the anti-bunching effect.展开更多
p-Terphenyls are aromatic compounds consisting of a central benzene ring substituted with two phenyl groups,and they are mainly isolated from terrestrial and marine organisms.The central ring of p-Terphenyls is usuall...p-Terphenyls are aromatic compounds consisting of a central benzene ring substituted with two phenyl groups,and they are mainly isolated from terrestrial and marine organisms.The central ring of p-Terphenyls is usually modified into more oxidized forms,e.g.,para quinone and phenols.In some cases,additional ring systems were observed on the terphenyl-type core structure or between two benzene moieties.p-Terphenyls have been reported to have cytotoxic,antimicrobial,antioxidant andα-glucosidase inhibitory effects.In this review,we will mainly summarize the structural diversity and biological activity of naturally occurring p-Terphenyls referring to the research works published before.展开更多
In order to discover structurally new and bioactive conipounds from marine life,we studied the secondary metabolites of the marine-derived fungi associated with a marine sponge(XS-3)from the Xisha islands.As a result,...In order to discover structurally new and bioactive conipounds from marine life,we studied the secondary metabolites of the marine-derived fungi associated with a marine sponge(XS-3)from the Xisha islands.As a result,4-O-methylcandidusin A(1),a new p-terphenyl alcohol,along with nine known analogs(2-10),were isolated and identified from the marine spongederived fungus Aspergillus candidus OUCMDZ-1051.The structures of these compounds were determined by analyzing spectroscopic data,especially ID and 2D NMR.The new compound 1 selectively inhibited the growth of the MDA-MB-46&BT474 and A431 human cancer cell lines with the IC_(50) values of 1.84,6.05 and 0.98 pmol/L,respectively.Compound 1 also displayed a selective antimicrobial activity against Escherichia coli with an MIC value of 27.3 pmol/L.The results indicated 4-O-methylcandidusin A(1)as a potential lead in the new drug discovery for triple negative breast cancer,invasive ductal breast cancer and epidermoid cancer.The antimicrobial metabolites also evidenced a clue for chemical defense of sponges by their associated microorganisms.展开更多
This paper describes the synthesis and free radical polymerization of 2,5 bis(4′ alkyloxyphenyl)styrene(M n ) for mesogen jacketed liquid crystal polymers(MJLCPs), where p terphenyl subsituted by alkoxy groups at bot...This paper describes the synthesis and free radical polymerization of 2,5 bis(4′ alkyloxyphenyl)styrene(M n ) for mesogen jacketed liquid crystal polymers(MJLCPs), where p terphenyl subsituted by alkoxy groups at both ends was used as mesogenic unit. Because of the absence of the polar linkage groups, such as —COO— or —CONH— as employed in the previous reported MJLCPs, M n is believed to be polymerized easily by both free radical polymerization and ionic polymerization. The chemical structure of M n was proved by 1H NMR, mass spectrometry and elementary analysis. Their phase transition and liquid crystallinity were characterized by DSC and POM. Although M 1, M 2, M 3 and M 4 exhibited monotropic nematic mesophase, M 5 displayed enantiotropic nematic mesophase presumably because of its decreased melting transition temperature. All monomers were easily polymerized to moderately high molecular weight polymers. At elevated temperature above T g, poly[2,5 bis(4′ alkoxyphenyl)styrene] showed a very stable mesophase. The formed birefrigence did not disappear until thermal decomposition started. Compared to other MJLCPs, the polymers reported here have much higher thermal stability. [WT5HZ]展开更多
Novel side-chain liquid-crystalline poly(meth)acrylates were synthesized using 1-(3-hydroxyl-propyl)-3-[(4 '-cyano-p-terphenyloxycarbonyl)alkyl]-1,1,3,3-tetramethyldisiloxane as the key intermediate. The polymers ...Novel side-chain liquid-crystalline poly(meth)acrylates were synthesized using 1-(3-hydroxyl-propyl)-3-[(4 '-cyano-p-terphenyloxycarbonyl)alkyl]-1,1,3,3-tetramethyldisiloxane as the key intermediate. The polymers used a disiloxane moiety as decoupling spacer with cyano-p-terphenyl as mesogenic unit. The products were characterized by NMR, GPC, DSC and polarizing optical microscopy. All the polymers with cyano-p-terphenyl mesogens formed a stable mesophase. However, if the mesogenic unit is replaced by cyano-p-biphenyl, the liquid crystalline character will be lost. The results also showed that the decoupling is incomplete even if a complex and very flexible decoupling spacer is deliberately incorporated to obtain the highest possible decoupling effect.展开更多
文摘A new p-terphenyl derivative 1 was isolated from the fruiting bodies of Boletopsis grisea. Its structure was established as 2. 3-diacetoxy-4 ', 4 ', 5, 6-tetrahydroxy-p-terphenyl by spectroscopic and chemical means.
基金Supported by the Project of Xuzhou Institute of Technology under Grant No XKY2014309the National Natural Science Foundation of China under Grant Nos 11304266 and 11447149
文摘We consider the photon emission statistical properties of a single molecule under pump-probe field driving, using the generating function method. The first- and second-order moments of statistical quantities are presented. Derived from the first-order moment, the line shapes are in good agreement with the experimental results. Derived from the second-order moment, Mandel＇s Q parameters show an obvious quantum effect of photon statistical distribution, i.e., the anti-bunching effect.
基金supported by the NSFC-Shandong Joint Fund(U1906212,U1606403)the Pilot National Laboratory for Marine Science and Technology(2018SDKJ0401-2,2016ASKJ08-02)+5 种基金the National Natural Science Foundation of China Major Project for Discovery of New Leading Compounds(81991522)the National Science and Technology Major Project for Significant New Drugs Development(2018ZX09735004)the Major National Science and Technology Projects of the Ministry of Science and Technology(81991522)the Fundamental Research Funds for the Central Universities(201941001)Project funded by China Postdoctoral Science Foundation(2017M622286)the Taishan Scholar Youth Expert Program in Shandong Province(tsqn201812021).
文摘p-Terphenyls are aromatic compounds consisting of a central benzene ring substituted with two phenyl groups,and they are mainly isolated from terrestrial and marine organisms.The central ring of p-Terphenyls is usually modified into more oxidized forms,e.g.,para quinone and phenols.In some cases,additional ring systems were observed on the terphenyl-type core structure or between two benzene moieties.p-Terphenyls have been reported to have cytotoxic,antimicrobial,antioxidant andα-glucosidase inhibitory effects.In this review,we will mainly summarize the structural diversity and biological activity of naturally occurring p-Terphenyls referring to the research works published before.
基金This work is supported by the National Natural Science Foundation of China(NSFC)(Nos.U1906213,41876172.and U1606403).
文摘In order to discover structurally new and bioactive conipounds from marine life,we studied the secondary metabolites of the marine-derived fungi associated with a marine sponge(XS-3)from the Xisha islands.As a result,4-O-methylcandidusin A(1),a new p-terphenyl alcohol,along with nine known analogs(2-10),were isolated and identified from the marine spongederived fungus Aspergillus candidus OUCMDZ-1051.The structures of these compounds were determined by analyzing spectroscopic data,especially ID and 2D NMR.The new compound 1 selectively inhibited the growth of the MDA-MB-46&BT474 and A431 human cancer cell lines with the IC_(50) values of 1.84,6.05 and 0.98 pmol/L,respectively.Compound 1 also displayed a selective antimicrobial activity against Escherichia coli with an MIC value of 27.3 pmol/L.The results indicated 4-O-methylcandidusin A(1)as a potential lead in the new drug discovery for triple negative breast cancer,invasive ductal breast cancer and epidermoid cancer.The antimicrobial metabolites also evidenced a clue for chemical defense of sponges by their associated microorganisms.
基金This work was supported by the National Natural Science Foundation of China(30470027 and 30225048)Natural Science Foundation of Yunnan Province(2005C0052Mand 2005C0011R).
文摘This paper describes the synthesis and free radical polymerization of 2,5 bis(4′ alkyloxyphenyl)styrene(M n ) for mesogen jacketed liquid crystal polymers(MJLCPs), where p terphenyl subsituted by alkoxy groups at both ends was used as mesogenic unit. Because of the absence of the polar linkage groups, such as —COO— or —CONH— as employed in the previous reported MJLCPs, M n is believed to be polymerized easily by both free radical polymerization and ionic polymerization. The chemical structure of M n was proved by 1H NMR, mass spectrometry and elementary analysis. Their phase transition and liquid crystallinity were characterized by DSC and POM. Although M 1, M 2, M 3 and M 4 exhibited monotropic nematic mesophase, M 5 displayed enantiotropic nematic mesophase presumably because of its decreased melting transition temperature. All monomers were easily polymerized to moderately high molecular weight polymers. At elevated temperature above T g, poly[2,5 bis(4′ alkoxyphenyl)styrene] showed a very stable mesophase. The formed birefrigence did not disappear until thermal decomposition started. Compared to other MJLCPs, the polymers reported here have much higher thermal stability. [WT5HZ]
基金This work was supported by NNSFC (No. 59873001).
文摘Novel side-chain liquid-crystalline poly(meth)acrylates were synthesized using 1-(3-hydroxyl-propyl)-3-[(4 '-cyano-p-terphenyloxycarbonyl)alkyl]-1,1,3,3-tetramethyldisiloxane as the key intermediate. The polymers used a disiloxane moiety as decoupling spacer with cyano-p-terphenyl as mesogenic unit. The products were characterized by NMR, GPC, DSC and polarizing optical microscopy. All the polymers with cyano-p-terphenyl mesogens formed a stable mesophase. However, if the mesogenic unit is replaced by cyano-p-biphenyl, the liquid crystalline character will be lost. The results also showed that the decoupling is incomplete even if a complex and very flexible decoupling spacer is deliberately incorporated to obtain the highest possible decoupling effect.
