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电针“神门”“太渊”穴对急性心肌缺血家兔听感觉门控电位P50的影响 被引量:6
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作者 余情 胡玲 +4 位作者 吴子建 蔡荣林 王洁 王春华 刘磊 《针刺研究》 CAS CSCD 北大核心 2014年第6期472-476,共5页
目的:探讨电针对急性心肌缺血家兔大脑皮层感觉门控的影响,以及不同经穴作用的相对特异性。方法:随机选择10只家兔作为正常组,余家兔冠状动脉结扎法复制急性心肌缺血模型。将模型复制成功的家兔随机分为模型组、神门组、太渊组,每组10... 目的:探讨电针对急性心肌缺血家兔大脑皮层感觉门控的影响,以及不同经穴作用的相对特异性。方法:随机选择10只家兔作为正常组,余家兔冠状动脉结扎法复制急性心肌缺血模型。将模型复制成功的家兔随机分为模型组、神门组、太渊组,每组10只。各电针组分别电针"神门""太渊"穴,刺激电流为1mA,频率为2Hz,刺激15min。采用BIOPAC生物信号采集系统观察各组家兔心率,利用美国NEUROSCAN ERPs工作站,记录各组家兔大脑皮层听感觉门控电位P 50变化情况。结果:与正常组比较,模型组心率下降(P<0.01),S 2-P 50波幅增大(P<0.01),S 2/S 1增大(P<0.01),S 1-S 2以及100×(1-S 2/S 1)减小(均P<0.01);与模型组比较,神门组家兔心率加快,S 2-P 50波幅减小(均P<0.01),S 2/S 1减小(P<0.01),S 1-S 2以及100×(1-S 2/S 1)增大(均P<0.01)。太渊组以上各指标均无明显改善,与神门组的差异均具有统计学意义(P<0.01)。结论:电针不同经穴对急性心肌缺血家兔大脑皮层感觉门控能力的调整作用具有相对特异性,电针心经原穴"神门"的调整作用优于电针肺经原穴"太渊"。 展开更多
关键词 急性心肌缺血 电针 神门 太渊 听感觉门控电位p50 穴位功能特异性
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P50 auditory sensory gating in first onset schizophrenics and normal healthy adults
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作者 WANG Hongxing ZHANG Mingdao +5 位作者 CHEN Xingshi LOU Feiying LIANG Jianhua CHEN Chong SHI Tiantao LU Qiulin 《Frontiers of Medicine》 SCIE CSCD 2007年第4期429-432,共4页
The aim of this research was to investigate the variations of P50 auditory sensory gating(P50)in normal healthy adults and the first onset schizophrenics.By using the American Nicolet Bravo electromyography/evoked pot... The aim of this research was to investigate the variations of P50 auditory sensory gating(P50)in normal healthy adults and the first onset schizophrenics.By using the American Nicolet Bravo electromyography/evoked potential(EMG/EP)system,P50 was measured with conditioning-testing paradigm(paired-click stimuli S1 and S2 were used)in 58 first onset schizophrenics and 108 healthy adults,and the Positive and Negative Syndrome Scale(PANSS)was applied.The following three conclusions have been reached.(1)In normal control(NC)group,measured from central,anterior and posterior zone(Cz,Fz and Pz respectively),there were no statistical differences(P>0.05)between S1 and S2 evoked P50 peak latencies(S1-P50 and S2-P50);the ampli-tudes of S2-P50[(2.2P1.4),(2.3P1.5)and(2.1P1.4)μV respectively]reduced significantly as compared with S1-P50[(5.6P3.3),(5.6P3.9)and(4.9P2.8)μV respectively](P<0.01);the S2/S1 ration,S1-S2 difference,and 100(1-S2/S1)had no statistical differences(P>0.05).(2)Compared with NC,the schizophrenic group significantly showed lower S1-P50 amplitudes(P<0.01,except at Pz in whichZ=2.030,P=0.042),higher S2-P50 amplitudes,higher S2/S1 ratio,lower S1-S2 difference,and more decreased 100(1-S2/S1)(P<0.01)at Cz,Fz and Pz.(3)No significant correlations were found among S2/S1 ratio,S1-S2,100(1-S2/S1)of sen-sory gating and PANSS(P>0.05)in schizophrenic group.The first onset schizophrenics had sensory gating deficits,which could be quantified by P50. 展开更多
关键词 SCHIZOpHRENIA brain ELECTROpHYSIOLOGY evoked potentials auditory p50 sensory gating
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