目的:测定评价Mapi Research Trust授权的便秘患者生存质量自评量表PAC-QOL中文版的信度、效度和反应度.方法:通过测定283例罗马Ⅲ标准诊断的功能性便秘患者的生存质量对PAC-QOL中文版进行评价.结果:通过探索性因子分析,量表可分为生理...目的:测定评价Mapi Research Trust授权的便秘患者生存质量自评量表PAC-QOL中文版的信度、效度和反应度.方法:通过测定283例罗马Ⅲ标准诊断的功能性便秘患者的生存质量对PAC-QOL中文版进行评价.结果:通过探索性因子分析,量表可分为生理、社会心理、担忧和满意度4个公因子,与原版量表基本一致;各条目与其所属领域的相关性有显著统计学意义(P<0.01);各领域及总分的内在信度Cronbachα系数除生理维度为0.69外,其余均在0.70以上;治疗1mo后与治疗前相比,各维度得分和总分有显著统计学差异(P<0.01);便秘患者治疗前与健康人群相比,各维度得分和总分有显著统计学差异(P<0.01).结论:PAC-QOL中文版具有较好的信度、效度和反应度,可用于中国便秘患者生存质量的测定.展开更多
目的探讨中药穴位贴敷联合情志护理干预在功能性便秘中的价值。方法选取福建中医药大学附属人民医院呼吸科2020年3月—2021年6月68例功能性便秘患者,随机分为对照组(采取常规治疗)与研究组(对照组基础上实施中药穴位贴敷联合情志护理干...目的探讨中药穴位贴敷联合情志护理干预在功能性便秘中的价值。方法选取福建中医药大学附属人民医院呼吸科2020年3月—2021年6月68例功能性便秘患者,随机分为对照组(采取常规治疗)与研究组(对照组基础上实施中药穴位贴敷联合情志护理干预),每组各34例。观察两组的疗效、便秘症状评分、汉密尔顿焦虑量表评分(Hamilton agitation scale,SAS)及汉密尔顿抑郁量表评分(Hamilton self-rating depression scale,SDS)、胃肠激素及肠动力学指标、便秘患者生活质量量表评分(quality of life scale for constipation patients,PAC-QOL)。结果研究组总效率为94.12%,明显高于对照组的73.53%(P<0.05)。治疗前两组便秘症状评分差异无统计学意义(P>0.05);治疗后研究组便秘症状积分下降程度明显低于对照组(P<0.05)。治疗前两组SAS评分及SDS指标差异无统计学意义(P>0.05);治疗后研究组SAS.SDS评分下降程度明显低于对照组(P<0.05)。治疗前两组胃肠激素及肠动力学指标差异无统计学意义(P>0.05);治疗后研究组生长抑素、直肠最大容量感觉阈值、肛管最大缩榨压、模拟排便肛管压指标均明显低于对照组,P物质及胃动素指标均明显高于对照组(P<0.05)。治疗前两组PAC-QOL评分差异无统计学意义(P>0.05);治疗研究组PAC-QOL下降程度明显低于对照组(P<0.05)。结论中药穴位贴敷联合情志护理干预措施的实施可增强功能性便秘病症治疗疗效果,明显改善患者临床症状及负面情绪,优化胃肠激素及肠动力学,提高生活质量。展开更多
Functional constipation(FC)is a chronic discasc that significantly afcts the life quality of patients.Acupuncture has been used for the treatment of FC for many years,but its effectiveness has not been scientifcally a...Functional constipation(FC)is a chronic discasc that significantly afcts the life quality of patients.Acupuncture has been used for the treatment of FC for many years,but its effectiveness has not been scientifcally assessed.The present study aimed to evaluate the efficacy of electro-acupuncture(EA)in relieving the symptoms,mental states and quality of life(QOL)of FC patients.A total of 96 FC patients were randomly allocated into EA,mosapride&sham EA group(MS)and mosapride control group(MC).In the EA group,patients were treated with 16 sessions of needling at Quchi(LI1I)and Shangjuxu(ST37)bilaterally,5 times a week in the first 2 weeks,and 3 times a.week in the last 2 weeks.In the MC group,patients were treated with 5 mg mosapride citrate three times a day for 4 weeks.In the MS group,patients underwent sham EA and the same mosapride citrate treatment as in the MC group.The primary outcome was the number of weekly spontaneous bowel movements(SBMs).The secondary outcomes included stool consistency,intensity of defecating difficulty,36-Item Short-Form Health Survey(SF-36),Self-rating Anxiety Scale(SAS),Self-rating Depression Scale(SDS),and the validated Patient Assessment of Constipation-Quality of Life(PAC-QOL).The results showed that as compared with the baseline,EA significantly improved the weekly SBMs,stool consistency and intensity of defecating difficulty(P<0.05).It also partly ameliorated the PAC-QOL,SF-36,SDS and SAS scores when compared with MC or MS group(P<0.05).However,no significant difference was observed between MS and MC groups in bowel function outcomes and QOL scores.It was concluded that EA could effectivcly improve bowel function,mental states and QOL of FC patients.展开更多
文摘目的:测定评价Mapi Research Trust授权的便秘患者生存质量自评量表PAC-QOL中文版的信度、效度和反应度.方法:通过测定283例罗马Ⅲ标准诊断的功能性便秘患者的生存质量对PAC-QOL中文版进行评价.结果:通过探索性因子分析,量表可分为生理、社会心理、担忧和满意度4个公因子,与原版量表基本一致;各条目与其所属领域的相关性有显著统计学意义(P<0.01);各领域及总分的内在信度Cronbachα系数除生理维度为0.69外,其余均在0.70以上;治疗1mo后与治疗前相比,各维度得分和总分有显著统计学差异(P<0.01);便秘患者治疗前与健康人群相比,各维度得分和总分有显著统计学差异(P<0.01).结论:PAC-QOL中文版具有较好的信度、效度和反应度,可用于中国便秘患者生存质量的测定.
文摘目的探讨中药穴位贴敷联合情志护理干预在功能性便秘中的价值。方法选取福建中医药大学附属人民医院呼吸科2020年3月—2021年6月68例功能性便秘患者,随机分为对照组(采取常规治疗)与研究组(对照组基础上实施中药穴位贴敷联合情志护理干预),每组各34例。观察两组的疗效、便秘症状评分、汉密尔顿焦虑量表评分(Hamilton agitation scale,SAS)及汉密尔顿抑郁量表评分(Hamilton self-rating depression scale,SDS)、胃肠激素及肠动力学指标、便秘患者生活质量量表评分(quality of life scale for constipation patients,PAC-QOL)。结果研究组总效率为94.12%,明显高于对照组的73.53%(P<0.05)。治疗前两组便秘症状评分差异无统计学意义(P>0.05);治疗后研究组便秘症状积分下降程度明显低于对照组(P<0.05)。治疗前两组SAS评分及SDS指标差异无统计学意义(P>0.05);治疗后研究组SAS.SDS评分下降程度明显低于对照组(P<0.05)。治疗前两组胃肠激素及肠动力学指标差异无统计学意义(P>0.05);治疗后研究组生长抑素、直肠最大容量感觉阈值、肛管最大缩榨压、模拟排便肛管压指标均明显低于对照组,P物质及胃动素指标均明显高于对照组(P<0.05)。治疗前两组PAC-QOL评分差异无统计学意义(P>0.05);治疗研究组PAC-QOL下降程度明显低于对照组(P<0.05)。结论中药穴位贴敷联合情志护理干预措施的实施可增强功能性便秘病症治疗疗效果,明显改善患者临床症状及负面情绪,优化胃肠激素及肠动力学,提高生活质量。
基金This study was supported by grants from the National Basic Research Program(No.2011CB505203)the National Natural Science Foundation of China(No.81603652,No.81874388).
文摘Functional constipation(FC)is a chronic discasc that significantly afcts the life quality of patients.Acupuncture has been used for the treatment of FC for many years,but its effectiveness has not been scientifcally assessed.The present study aimed to evaluate the efficacy of electro-acupuncture(EA)in relieving the symptoms,mental states and quality of life(QOL)of FC patients.A total of 96 FC patients were randomly allocated into EA,mosapride&sham EA group(MS)and mosapride control group(MC).In the EA group,patients were treated with 16 sessions of needling at Quchi(LI1I)and Shangjuxu(ST37)bilaterally,5 times a week in the first 2 weeks,and 3 times a.week in the last 2 weeks.In the MC group,patients were treated with 5 mg mosapride citrate three times a day for 4 weeks.In the MS group,patients underwent sham EA and the same mosapride citrate treatment as in the MC group.The primary outcome was the number of weekly spontaneous bowel movements(SBMs).The secondary outcomes included stool consistency,intensity of defecating difficulty,36-Item Short-Form Health Survey(SF-36),Self-rating Anxiety Scale(SAS),Self-rating Depression Scale(SDS),and the validated Patient Assessment of Constipation-Quality of Life(PAC-QOL).The results showed that as compared with the baseline,EA significantly improved the weekly SBMs,stool consistency and intensity of defecating difficulty(P<0.05).It also partly ameliorated the PAC-QOL,SF-36,SDS and SAS scores when compared with MC or MS group(P<0.05).However,no significant difference was observed between MS and MC groups in bowel function outcomes and QOL scores.It was concluded that EA could effectivcly improve bowel function,mental states and QOL of FC patients.
