CMIP 6 models simulation of the connection between North/South Pacific Meridional Mode and ENSO

The subtropical North and South Pacific Meridional Modes(NPMM and SPMM)are well known precursors of El Niño-Southern Oscillation(ENSO).However,relationship between them is not constant.In the early 1980,the relationship experienced an interdecadal transition.Changes in this connection can be attributed mainly to the phase change of the Pacific decadal oscillation(PDO).During the positive phase of PDO,a shallower thermocline in the central Pacific is responsible for the stronger trade wind charging(TWC)mechanism,which leads to a stronger equatorial subsurface temperature evolution.This dynamic process strengthens the connection between NPMM and ENSO.Associated with the negative phase of PDO,a shallower thermocline over southeastern Pacific allows an enhanced wind-evaporation-SST(WES)feedback,strengthening the connection between SPMM and ENSO.Using 35 Coupled Model Intercomparison Project Phase 6(CMIP6)models,we examined the NPMM/SPMM performance and its connection with ENSO in the historical runs.The great majority of CMIP6 models can reproduce the pattern of NPMM and SPMM well,but they reveal discrepant ENSO and NPMM/SPMM relationship.The intermodal uncertainty for the connection of NPMM-ENSO is due to different TWC mechanism.A stronger TWC mechanism will enhance NPMM forcing.For SPMM,few models can simulate a good relationship with ENSO.The intermodel spread in the relationship of SPMM and ENSO owing to SST bias in the southeastern Pacific,as WES feedback is stronger when the southeastern Pacific is warmer.

A Physics-informed Deep-learning Intensity Prediction Scheme for Tropical Cyclones over the Western North Pacific

Accurate prediction of tropical cyclone(TC)intensity is challenging due to the complex physical processes involved.Here,we introduce a new TC intensity prediction scheme for the western North Pacific(WNP)based on a time-dependent theory of TC intensification,termed the energetically based dynamical system(EBDS)model,together with the use of a long short-term memory(LSTM)neural network.In time-dependent theory,TC intensity change is controlled by both the internal dynamics of the TC system and various environmental factors,expressed as environmental dynamical efficiency.The LSTM neural network is used to predict the environmental dynamical efficiency in the EBDS model trained using besttrack TC data and global reanalysis data during 1982–2017.The transfer learning and ensemble methods are used to retrain the scheme using the environmental factors predicted by the Global Forecast System(GFS)of the National Centers for Environmental Prediction during 2017–21.The predicted environmental dynamical efficiency is finally iterated into the EBDS equations to predict TC intensity.The new scheme is evaluated for TC intensity prediction using both reanalysis data and the GFS prediction data.The intensity prediction by the new scheme shows better skill than the official prediction from the China Meteorological Administration(CMA)and those by other state-of-art statistical and dynamical forecast systems,except for the 72-h forecast.Particularly at the longer lead times of 96 h and 120 h,the new scheme has smaller forecast errors,with a more than 30%improvement over the official forecasts.

Track-Pattern-Based Characteristics of Extratropical Transitioning Tropical Cyclones in the Western North Pacific

Based on the Regional Specialized Meteorological Center(RSMC)Tokyo-Typhoon Center best-track data and the NCEP-NCAR reanalysis dataset,extratropical transitioning(ET)tropical cyclones(ETCs)over the western North Pacific(WNP)during 1951–2021 are classified into six clusters using the fuzzy c-means clustering method(FCM)according to their track patterns.The characteristics of the six hard-clustered ETCs with the highest membership coefficient are shown.Most tropical cyclones(TCs)that were assigned to clusters C2,C5,and C6 made landfall over eastern Asian countries,which severely threatened these regions.Among landfalling TCs,93.2%completed their ET after landfall,whereas 39.8%of ETCs completed their transition within one day.The frequency of ETCs over the WNP has decreased in the past four decades,wherein cluster C5 demonstrated a significant decrease on both interannual and interdecadal timescales with the expansion and intensification of the western Pacific subtropical high(WPSH).This large-scale circulation pattern is favorable for C2 and causes it to become the dominant track pattern,owning to it containing the largest number of intensifying ETCs among the six clusters,a number that has increased insignificantly over the past four decades.The surface roughness variation and three-dimensional background circulation led to C5 containing the maximum number of landfalling TCs and a minimum number of intensifying ETCs.Our results will facilitate a better understanding of the spatiotemporal distributions of ET events and associated environment background fields,which will benefit the effective monitoring of these events over the WNP.

Non-Targeted Metabolomics Reveals the Metabolic Alterations in Response to Artificial Selective Breeding in the Fast-Growing Strains of Pacific Oyster

Pacific oyster(Crassostrea gigas)is one of the most important mollusks cultured all around the world.Selective breeding programs of Pacific oysters in China is initiated since 2006 and developed the genetically improved strain with fast-growing trait.However,little is known about the metabolic signatures of the fast-growing trait.In the present study,the non-targeted metabolomics was performed to analyze the metabolic signatures of adductor muscle tissue in one-year old Pacific oysters from fast-growing strain and the wild population.A total of 7767 and 10174 valid peaks were extracted and quantified in ESI^(+)and ESI^(−)modes,resulting in 399 and 381 annotated metabolites,respectively.PCA and OPLS-DA revealed that considerable separation among samples from fastgrowing strain and wild population,suggesting the differences in metabolic signatures.Meanwhile,81 significantly different metabolites(SDMs)were identified in the comparisons between fast-growing strain and wild population,based on the strict thresholds.It was found that there were highly correlation and conserved coordination among these SDMs.KEGG enrichment analysis indicated that the SDMs were tightly related to pantothenate and CoA biosynthesis,steroid hormone biosynthesis,riboflavin metabolism,and arginine and proline metabolism.Of them,the CoA biosynthesis and metabolism,affected by pantetheine and pantothenic acid,might be important for the growth of Pacific oysters under artificial selective breeding.The study provides the comprehensive views of metabolic signatures in response to artificially selective breeding,and is helpful to better understand the molecular mechanism of fastgrowing traits in Pacific oysters.

Influence of the Atlantic Multidecadal Oscillation and Interdecadal Pacific Oscillation on Antarctic surface air temperature during 1900 to 2015

The importance of the Atlantic Multidecadal Oscillation(AMO)and Interdecadal Pacific Oscillation(IPO)in influencing zonally asymmetric changes in Antarctic surface air temperature(SAT)has been established.However,previous studies have primarily concentrated on examining the combined impact of the contrasting phases of the AMO and IPO,which have been dominant since the advent of satellite observations in 1979.This study utilizes long-term reanalysis data to investigate the impact of four combinations of+AMO+IPO,–AMO–IPO,+AMO–IPO,and–AMO+IPO on Antarctic SAT over the past 115 years.The+AMO phase is characterized by a spatial mean temperature amplitude of up to 0.5℃over the North Atlantic Ocean,accompanied by positive sea surface temperature(SST)anomalies in the tropical eastern Pacific and negative SST anomalies in the extratropical-mid-latitude western Pacific,which are indicative of the+IPO phase.The Antarctic SAT exhibits contrasting spatial patterns during the+AMO+IPO and+AMO–IPO periods.However,during the–AMO+IPO period,apart from the Antarctic Peninsula and the vicinity of the Weddell Sea,the entire Antarctic region experiences a warming trend.The most pronounced signal in the SAT anomalies is observed during the austral autumn,whereas the combination of–AMO and–IPO exhibits the smallest magnitude across all the combinations.The wavetrain excited by the SST anomalies associated with the AMO and IPO induces upper-level and surface atmospheric circulation anomalies,which alter the SAT anomalies.Furthermore,downward longwave radiation anomalies related to anomalous cloud cover play a crucial role.In the future,if the phases of AMO and IPO were to reverse(AMO transitioning to a negative phase and IPO transitioning to a positive phase),Antarctica could potentially face more pronounced warming and accelerated melting compared to the current observations.

Seasonal Prediction of the Record-Breaking Northward Shift of the Western Pacific Subtropical High in July 2021

The unprecedented Zhengzhou heavy rainfall in July 2021 occurred under the background of a northward shift of the western Pacific subtropical high(WPSH).Although the occurrence of this extreme event could not be captured by seasonal predictions,a skillful prediction of the WPSH variation might have warned us of the increased probability of extreme weather events in Central and Northern China.However,the mechanism for the WPSH variation in July 2021 and its seasonal predictability are still unknown.Here,the observed northward shift of the WPSH in July 2021 is shown to correspond to a meridional dipole pattern of the 850-hPa geopotential height to the east of China,the amplitude of which became the strongest since 1979.The meridional dipole pattern is two nodes of the Pacific–Japan pattern.To investigate the predictability of the WPSH variation,a 21-member ensemble of seasonal predictions initiated from the end of June 2021 was conducted.The predictable and unpredictable components of the meridional dipole pattern were identified from the ensemble simulations.Its predictable component is driven by positive precipitation anomalies over the tropical western Pacific.The positive precipitation anomalies are caused by positive horizonal advection of the mean moist enthalpy by southwesterly anomalies to the northwestern flank of anticyclonic anomalies excited by the existing La Niña,which is skillfully predicted by the model.The leading mode of the unpredictable component is associated with the atmospheric internal intraseasonal oscillations,which are not initialized in the simulations.The relative contributions of the predictable and unpredictable components to the observed northward shift of the WPSH at 850 hPa are 28.0%and 72.0%,respectively.

Interdecadal Enhancement in the Relationship between the Western North Pacific Summer Monsoon and Sea Surface Temperature in the Tropical Central-Western Pacific after the Early 1990s

This study reveals the strengthened interdecadal relationship between the western North Pacific summer monsoon(WNPSM)and tropical central-western Pacific sea surface temperature anomaly(SSTA)in summer after the early 1990s.In the first period(1979–91,P1),the WNPSM-related precipitation anomaly and horizontal wind anomaly present themselves as an analogous Pacific-Japan(PJ)-like pattern,generally considered to be related to the Niño-3 index in the preceding winter.During the subsequent period(1994–2019,P2),the WNPSM-related precipitation anomaly presents a zonal dipole pattern,correlated significantly with the concurrent SSTA in the Niño-4 and tropical western Pacific regions.The negative(positive)SSTA in the tropical western Pacific and positive(negative)SSTA in the Niño-4 region,could work together to influence the WNPSM,noting that the two types of anomalous SSTA configurations enhance(weaken)the WNPSM by the positive(negative)phase PJ-like wave and Gill response,respectively,with an anomalous cyclone(anticyclone)located in the WNPSM,which shows obvious symmetry about the anomalous circulation.Specifically,the SSTA in Niño-4 impacts the WNPSM by an atmospheric Gill response,with a stronger(weaker)WNPSM along with a positive(negative)SSTA in the Niño-4 region.Furthermore,the SSTA in the tropical western Pacific exerts an influence on the WNPSM by a PJ-like wave,with a stronger(weaker)WNPSM along with a negative(positive)SSTA in the tropical western Pacific.In general,SSTAs in the tropical western Pacific and Niño-4 areas could work together to exert influence on the WNPSM,with the effect most likely to occur in the El Niño(La Niña)developing year in P2.However,the SSTAs in the tropical western Pacific worked alone to exert an influence on the WNPSM mainly in 2013,2014,2016,and 2017,and the SSTAs in the Niño-4 region worked alone to exert an influence on the WNPSM mainly in Central Pacific(CP)La Niña developing years.The sensitivity experiments also can reproduce the PJ-like wave/Gill response associated with SSTA in the tropical western Pacific/Niño-4 regions.Therefore,the respective and synergistic impacts from the Niño-4 region and the tropical western Pacific on the WNPSM have been revealed,which helps us to acquire a better understanding of the interdecadal variations of the WNPSM and its associated climate influences.

Climate-Related Variations in Autumn Cohort of Japanese Common Squid Todarodes pacificus

The Japanese common squid Todarodes pacificus is widely distributed in the Sea of Japan,the East China Sea and the Northwest Pacific Ocean,and is largely exploited by the Asia-Pacific countries.In this study,the impacts of regime shift of the Pacific Decadal Oscillation(PDO)during 1977-2015 on the autumn cohort of T.pacificus were assessed by examining the variations in vertical water temperatures at depths of 0 m(Temp_0 m),50 m(Temp_50 m)and 100 m(Temp_100 m)and the distribution pattern of preferred spawning ground(SSG).Spatial and temporal correlation analysis revealed that the PDO index exhibited a significantly negative relationship with vertical water temperatures at different depths and was negatively related to catch-per-unit-effort(CPUE)and stock biomass of T.pacificus.In addition,water temperatures in the specific three water layers were positively associated with CPUE.The PDO regime shift strongly affected the thermal condition and spawning ground of T.pacificus.Comparing to the negative PDO,the waters from the surface to the deep became cool in the positive PDO phase;correspondingly,the area of SSG largely contracted at different depths.Consequently,the CPUE and stock biomass of T.pacificus profoundly decreased.From the results it can be concluded that the PDO regime shift-driven changes in vertical thermal condition and SSG ranges can yield substantial impacts on T.pacificus abundance.

Recent Enhancement in Co-Variability of the Western North Pacific Summer Monsoon and the Equatorial Zonal Wind

The western North Pacific summer monsoon(WNPSM)is an important subcomponent of the Asian summer monsoon.The equatorial zonal wind(EZW)in the lower troposphere over the western Pacific may play a critical role in the evolution of the El Niño-Southern Oscillation(ENSO).The possible linkage between the EZW over the western Pacific and the offequatorial monsoonal winds associated with the WNPSM and its decadal changes have not yet been fully understood.Here,we find a non-stationary relationship between the WNPSM and the western Pacific EZW,significantly strengthening their correlation around the late 1980s/early 1990s.This observed shift in the WNPSM–EZW relationship could be explained by the changes in the related sea surface temperature(SST)configurations across the tropical oceans.The enhanced influence from the springtime tropical North Atlantic,summertime tropical central Pacific,and maritime continent SST anomalies may be working together in contributing to the recent intensified WNPSM–EZW co-variability.The observed recent strengthening of the WNPSM–EZW relationship may profoundly impact the climate system,including prompting more effective feedback from the WNPSM on subsequent ENSO evolution and bolstering a stronger biennial tendency of the WNPSM–ENSO coupled system.The results obtained herein imply that the WNPSM,EZW,ENSO,and the tropical North Atlantic SST may be closely linked within a unified climate system with a quasi-biennial rhythm occurring during recent decades,accompanied by a reinforcement of the WNPSM–ENSO interplay quite possibly triggered by enhanced tropical Pacific–Atlantic cross-basin interactions.These results highlight the importance of the tropical Atlantic cross-basin influences in shaping the spatial structure of WNPSM-related wind anomalies and the WNPSM–ENSO interaction.

Near-infrared spectroscopy method for rapid proximate quantitative analysis of nutrient composition in Pacific oyster Crassostrea gigas

Glycogen,amino acids,fatty acids,and other nutrient components affect the flavor and nutritional quality of oysters.Methods based on near-infrared reflectance spectroscopy(NIRS)were developed to rapidly and proximately determine the nutrient content of the Pacific oyster Crassostreagigas.Samples of C.gigas from 19 costal sites were freeze-dried,ground,and scanned for spectral data collection using a Fourier transform NIR spectrometer(Thermo Fisher Scientific).NIRS models of glycogen and other nutrients were established using partial least squares,multiplication scattering correction first-order derivation,and Norris smoothing.The R_(C) values of the glycogen,fatty acids,amino acids,and taurine NIRS models were 0.9678,0.9312,0.9132,and 0.8928,respectively,and the residual prediction deviation(RPD)values of these components were 3.15,2.16,3.11,and 1.59,respectively,indicating a high correlation between the predicted and observed values,and that the models can be used in practice.The models were used to evaluate the nutrient compositions of 1278 oyster samples.Glycogen content was found to be positively correlated with fatty acids and negatively correlated with amino acids.The glycogen,amino acid,and taurine levels of C.gigas cultured in the subtidal and intertidal zones were also significantly different.This study suggests that C.gigas NIRS models can be a cost-effective alternative to traditional methods for the rapid and proximate analysis of various slaughter traits and may also contribute to future genetic and breeding-related studies in Pacific oysters.

The Influence of Meridional Variation in North Pacific Sea Surface Temperature Anomalies on the Arctic Stratospheric Polar Vortex

This study examines the dependence of Arctic stratospheric polar vortex(SPV)variations on the meridional positions of the sea surface temperature(SST)anomalies associated with the first leading mode of North Pacific SST.The principal component 1(PC1)of the first leading mode is obtained by empirical orthogonal function decomposition.Reanalysis data,numerical experiments,and CMIP5 model outputs all suggest that the PC1 events(positive-minus-negative PC1 events),located relatively northward(i.e.,North PC1 events),more easily weaken the Arctic SPV compared to the PC1 events located relatively southward(i.e.,South PC1 events).The analysis indicates that the North PC1-related Aleutian low anomaly is located over the northern North Pacific and thus enhances the climatological trough,which strengthens the planetary-scale wave 1 at mid-to-high latitudes and thereby weakens the SPV.The weakened stratospheric circulation further extends into the troposphere and favors negative surface temperature anomalies over Eurasia.By contrast,the South PC1-related Aleutian low anomaly is located relatively southward,and its constructive interference with the climatological trough is less efficient at high latitudes.Thus,the South PC1 events could not induce an evident enhancement of the planetary-scale waves at high latitudes and thereby a weakening of the SPV on average.The Eurasian cooling associated with South PC1 events(positive-minus-negative PC1 events)is also not prominent.The results of this study suggest that the meridional positions of the PC1 events may be useful for predicting the Arctic SPV and Eurasian surface temperature variations.

The combined effects of North Atlantic Oscillation and Western Pacific teleconnection on winter temperature in Eastern Asia during 1980−2021

As important atmospheric circulation patterns in Northern Hemisphere(NH),the North Atlantic Oscillation(NAO)and the Western Pacific teleconnection(WP)affect the winter climate in Eurasia.In order to explore the combined effects of NAO and WP on East Asian(EA)temperature,the NAO and WP indices are divided into four phases from 1980−2021:the positive NAO and WP phase(NAO+/WP+),the negative NAO and WP phase(NAO−/WP−),the positive NAO and negative WP phase(NAO+/WP−),the negative NAO and positive WP phase(NAO−/WP+).In the phase of NAO+/WP+,the low geopotential height(GH)stays in north of EA at 50°−80°N;the surface air temperature anomaly(SATA)is 0.8−1℃lower than Southern Asian.In the phase of NAO−/WP−,the center of high temperature and GH locate in the northeast of EA;the cold air spreads to Southern Asia,causing the SATA decreases 1−1.5℃.In the phase of NAO+/WP−,the high GH belt is formed at 55°−80°N.Meanwhile,the center of high SATA locates in the north of Asia that increases 0.8−1.1℃.The cold airflow causes temperature dropping 0.5−1℃in the south of EA.The SATA improves 0.5−1.5℃in south of EA in the phase of NAO−/WP+.The belt of high GH is formed at 25°−50°N,and blocks the cold air which from Siberia.The NAO and WP generate two warped plate pressure structures in NH,and affect the temperature by different pressure configurations.NAO and WP form different GH,and GH acts to block and push airflow by affecting the air pressure,then causes the temperature to be different from the north and south of EA.Finally,the multiple linear regression result shows that NAO and WP are weakened by each other such as the phase of NAO+/WP+and NAO−/WP−.

Comparison of multiple salinity datasets:upper ocean salinity and stratification in the tropical Pacific during the Argo period

Ocean salinity is an important variable that affects the ocean stratification.We compared the salinity and ocean stratification in the tropical Pacific derived from the Argo(Array for Real-time Geostrophic Oceanography data),EN4(Ensemble 4 analysis),SODA(the Simple Ocean Data Assimilation reanalysis),IAP(Institute of Atmospheric Physics data),and ORAS4(Ocean Reanalysis System 4)over 2005–2017.Results show that the spatial distribution of climatological mean of sea surface salinity(SSS)in all the products is consistent,and the low salinity region showed large deviation and strong dispersion.The Argo has the smallest RMSE and the highest correlation with the ensemble mean,while the IAP shows a high-salinity deviations relative to other datasets.All the products show high positive correlations between the sea surface density(SSD)and SSS with respect to the deviations of climatological mean from ensemble mean,suggesting that the SSD deviation may be mainly influenced by the SSS deviation.In the aspect of the ocean stratification,the mixed layer depth(MLD)climatological mean in the Argo shows the highest correlation with the ensemble mean,followed by EN4,IAP,ORAS4,and SODA.The Argo and EN4 show thicker barrier layer(BL)relative to the ensemble mean while the SODA displays the largest negative deviation in the tropical western Pacific.Furthermore,the EN4,ORAS4,and IAP underestimate the stability in the upper ocean at the depths of 20–140 m,while Argo overestimates ocean stability.The salinity fronts in the western-central equatorial Pacific from Argo,EN4,and ORAS4 are consistent,while those from SODA and IAP show large deviations with a westward position in amplitude of 0°–6°and 0°–10°,respectively.The SSS trend patterns from all the products are consistent in having ensemble mean with high spatial correlations of 0.95–0.97.

Performance Evaluation of Three Parameterizations on Internal Tidal Mixing in the Northern Pacific

The accurate assessment of the energy dissipation of internal tides(ITs)is of great importance because ITs contribute significantly to abyssal mixing.Thus,in this study,the IT-driven dissipation and diapycnal diffusion in the northern Pacific are esti-mated using parameterizations proposed by St.Laurent et al.(2002),Koch-Larrouy et al.(2007),and de Lavergne et al.(2020)(hereaf-ter referred to as LSJ02,KL07,and dL20,respectively).The performances of the three parameterizations are evaluated by comparing the calculated results with fine structure observations.In particular,the dissipation estimated by LSJ02 parameterization shows a bottom-intensified characteristic,with the patterns showing good agreement with the observations near seamounts.Moreover,43%of the results calculated using the LSJ02 parameterization have errors lower than one order of magnitude in the generation sites of ITs.Meanwhile,the strongest dissipation estimated by the KL07 parameterization shifts to the thermocline,with the results showing the highest level of consistency with observations in the generation sites.The proportion of results with errors lower than one order of magnitude is 80.7%.Furthermore,the results calculated by dL20 parameterization agree well with the observations in the upper and middle layers,with the parameterization showing an accurate estimation of the remote dissipation.The percentages of the errors lower than one order of magnitude between the dL20 parameterization and observations account for 77.1%and 88.7%in the genera-tion sites and far-field regions,respectively.

Asymmetry of Salinity Variability in the Tropical Pacific during Interdecadal Pacific Oscillation Phases

It has been recognized that salinity variability in the tropical Pacific is closely related to the Interdecadal Pacific Oscillation(IPO).Here,we use model simulations from 1900 to 2017 to illustrate obvious asymmetries of salinity variability in the tropical Pacific during positive and negative IPO phases.The amplitude of salinity variability in the tropical Pacific during positive IPO phases is larger than that during negative IPO phases,with a more westward shift of a large Sea Surface Salinity(SSS)anomaly along the equator.Salinity budget analyses show that the asymmetry of salinity variability during positive and negative IPO phases is dominated by the difference in the surface forcing associated with the freshwater flux[FWF,precipitation(P)minus evaporation(E)],with a contribution of 40%–50%near the dateline on the equator.Moreover,the relationships between the salinity variability and its budget terms also show differences in their leadlag correlations during positive and negative IPO phases.These differences in salinity variability during different IPO phases produce asymmetric effects on seawater density which can reduce or enhance upper-ocean stratification.Therefore,the salinity effects may modulate the intensity of El Nino-Southern Oscillation(ENSO),resulting in an enhanced(reduced)El Nino but a reduced(enhanced)La Ni?a during positive(negative)IPO phases by 1.6℃psu^(-1)(1.3℃psu^(-1)),respectively.It is suggested that the asymmetry of salinity variability may be related to the recent change in ENSO amplitude associated with the IPO,which can help elucidate ENSO diversity.

Understanding the Development of the 2018/19 Central Pacific El Niño

A central Pacific(CP)El Niño event occurred in 2018/19.Previous studies have shown that different mechanisms are responsible for different subtypes of CP El Niño events(CP-I El Niño and CP-II El Niño).By comparing the evolutions of surface winds,ocean temperatures,and heat budgets of the CP-I El Niño,CP-II El Niño,and 2018/19 El Niño,it is illustrated that the subtropical westerly anomalies in the North Pacific,which led to anomalous convergence of Ekman flow and surface warming in the central equatorial Pacific,played an important role in the 2018/19 El Niño event as well as in the CP-II El Niño.Although the off-equatorial forcing played a vital role,it is found that the equatorial forcing acted as a driving(damping)term in boreal spring(summer)of the 2018/19 El Niño.The 2018/19 El Niño provides a timely and vivid example that helps illustrate the proposed mechanism of the CP El Niño,which could be leveraged to improve El Niño predictability.

Extraction of Natural Nanostructured Hydroxyapatite from Pacific Cod(Gadus macrocephalus)Bone with a Thermostable Collagenolytic Protease and Its ex vivo Intestinal Bioavailability

Natural nano-hydroxyapatite(HA)was extracted from Pacific cod(Gadus macrocephalus)bone with a thermostable col-lagenolytic protease in the present study.Conditions for the enzymatic reaction were optimized to be 60℃and pH 7.0,and a desir-able extraction efficiency was achieved by using the crude collagenolytic protease.Dynamic light scattering,transmission electron microscopy and energy-dispersive X-ray analysis revealed that nano-HA are anionic spherical(about 110nm)particles mainly com-prised of calcium and phosphorus at an approximate ratio of 5:3.As evaluated with the mouse ex vivo intestinal segments,the extracted nano-HA displayed comparable level of intestinal bioavailability to the positive control CaCl_(2).By treating with inhibitors(NaN3,ami-loride)and low temperature(4℃),clathrin-mediated endocytosis was assumed to involve the intestinal absorption of nano-HA.Over-all,the application of thermostable collagenolytic protease is proved to be a promising alternative method for nano-HA extraction from natural resource with improved ecological and biological value.

Coupling between the Cenozoic west Pacific subduction initiation and decreases of atmospheric carbon dioxides

At the beginning of the Cenozoic,the atmospheric CO_(2)concentration increased rapidly from~2000 ppmv at 60 Ma to~4600 ppmv at 51 Ma,which is 5–10 times higher than the present value,and then continuous declined from~51 to 34 Ma.The cause of this phenomenon is still not well understood.In this study,we demonstrate that the initiation of Cenozoic west Pacific plate subduction,triggered by the hard collision in the Tibetan Plateau,occurred at approximately 51 Ma,coinciding with the tipping point.The water depths of the Pacific subduction zones are mostly below the carbonate compensation depths,while those of the Neo-Tethys were much shallower before the collision and caused far more carbonate subducting.Additionally,more volcanic ashes erupted from the west Pacific subduction zones,which consume CO_(2).The average annual west Pacific volvano eruption is 1.11 km~3,which is higher than previous estimations.The amount of annual CO_(2)absorbed by chemical weathering of additional west Pacific volcanic ashes could be comparable to the silicate weathering by the global river.We propose that the initiation of the western Pacific subduction controlled the long-term reduction of atmospheric CO_(2)concentration.

Response of the North Pacific Storm Track Activity in the Cold Season to Multi-scale Oceanic Variations of Kuroshio Extension System: A Statistical Assessment

In this paper,a statistical method called Generalized Equilibrium Feedback Analysis(GEFA)is used to investigate the responses of the North Pacific Storm Track(NPST)in the cold season to the multi-scale oceanic variations of the Kuroshio Extension(KE)system,including its large-scale variation,oceanic front meridional shift,and mesoscale eddy activity.Results show that in the cold season from the lower to the upper troposphere,the KE large-scale variation significantly weakens the storm track activity over the central North Pacific south of 30°N.The northward shift of the KE front significantly strengthens the storm track activity over the western and central North Pacific south of 40°N,resulting in a southward shift of the NPST.In contrast,the NPST response to KE mesoscale eddy activity is not so significant and relatively shallow,which only shows some significant positive signals near the dateline in the lower and middle troposphere.Furthermore,it is found that baroclinicity and baroclinic energy conversion play an important role in the formation of the NPST response to the KE multi-scale oceanic variations.

An Assessment of the Effect and Prospect of the US Indo-Pacific Strategy

Since the Trump administration,the national security strategy of the United States has focused on addressing the major power competition and regarded China as its main strategic competitor,which has been profoundly reflected in its introduction of the Indo-Pacific Strategy.The United States has certain resource advantages in the process of advancing the Indo-Pacific Strategy,and has made some progress of it.Nonetheless,the prospect of the strategy does not entirely depend on the will and action of the United States,but also on the joint action of other elements.