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SYNTHESIS AND pH-SENSITIVE SELF-ASSEMBLY OF DENDRITIC POLY(AMIDOAMINE)-b-POLY(L-GLUTAMATE) BIOHYBRIDS
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作者 董常明 《Chinese Journal of Polymer Science》 SCIE CAS CSCD 2009年第6期797-805,共9页
Dendritic poly(amidoamine)-b-poly(L-glutamate)(PAMAM-b-PLG) biohybrids were synthesized by the ring-opening polymerization ofγ-benzyl-L-glutamate N-carboxyanhydride monomer,followed by the deprotection of benzyl grou... Dendritic poly(amidoamine)-b-poly(L-glutamate)(PAMAM-b-PLG) biohybrids were synthesized by the ring-opening polymerization ofγ-benzyl-L-glutamate N-carboxyanhydride monomer,followed by the deprotection of benzyl groups on poly(benzyl-L-glutamate),and were characterized by ~1H-NMR,FT-IR and gel permeation chromatography.The self-assembly behavior of the PAMAM-b-PLG biohybrid was investigated by means of UV-Vis,dynamic light scattering (DLS),transmission electronic microscopy(TEM) and ~1H-NMR.UV-Vis analysis ... 展开更多
关键词 Dendritic pamam-b-plg pH-sensitive self-assembly Nanoparticles Drug/gene delivery
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