Acute pancreatitis(AP)is one of the most common diseases.AP is associated with significant morbidity and mortality,but it lacks specific and effective therapies.Traditional Chinese medicine(TCM)is one of the most popu...Acute pancreatitis(AP)is one of the most common diseases.AP is associated with significant morbidity and mortality,but it lacks specific and effective therapies.Traditional Chinese medicine(TCM)is one of the most popular complementary and alternative medicine modalities worldwide for the treatment of AP.The current evidence from basic research and clinical studies has shown that TCM has good therapeutic effects on AP.This review summarizes the widely used formulas,single herbs and monomers that are used to treat AP and the potential underlying mechanisms of TCM.Because of the abundance,low cost,and safety of TCM as well as its ability to target various aspects of the pathogenesis,TCM provides potential clinical benefits and a new avenue with tremendous potential for the future treatment of AP.展开更多
Objective:To determine medication regularity external therapies of Traditional Chinese medicine of eczema by data mining.Methods:Papers were retrieved from databases Pubmed,CNKI,WF,VIP,CBM,Web of Science and Embase.Fr...Objective:To determine medication regularity external therapies of Traditional Chinese medicine of eczema by data mining.Methods:Papers were retrieved from databases Pubmed,CNKI,WF,VIP,CBM,Web of Science and Embase.From the establishment of the database to April 2020 were searched.The main points of Medication Regularity were established with Excel 2016 software;the characteristics and laws in external therapies of Traditional Chinese medicine Treatment of eczema were analyzed with the relevance rule and cluster analysis Methods in data mining technology.Results:The property and flavor of the herbs mainly used were cold,bitter,while the channel which are mostly involved included liver meridian,lung meridian and Bladder Meridian,The analysis of association rules showed that kushen and difuzi had the highest correlation.The clustering analysis figured out 7groups of the herbs.Conclusion:The study presents the common pair herbs in the treatment of external therapies of Traditional Chinese medicine of eczema,which provides the approach to syndrome differentiation and medication in clinical treatment of eczema.展开更多
目的总结中药治疗耳鸣的核心方药及配伍规律。方法检索中国期刊全文数据库(CNKI)、PubMed、Web of Science等数据库中关于中药治疗耳鸣的临床研究文献。建立处方及药物信息数据库,统计药物频次及功效分类,并对其进行复杂网络分析。结果...目的总结中药治疗耳鸣的核心方药及配伍规律。方法检索中国期刊全文数据库(CNKI)、PubMed、Web of Science等数据库中关于中药治疗耳鸣的临床研究文献。建立处方及药物信息数据库,统计药物频次及功效分类,并对其进行复杂网络分析。结果最终获取103首方剂,应用中药151味,总频次为1142次,涉及补虚药、活血化瘀药等17类药物。频次前3位中药为石菖蒲(63)、柴胡(45)、当归(42)。通过复杂网络分析得出,常用药对频次前3位为石菖蒲-丹参、石菖蒲-柴胡、石菖蒲-葛根,核心处方为石菖蒲、熟地黄、山萸肉、山药、柴胡、葛根、川芎、丹参、磁石。结论中药治疗耳鸣主要以益气升阳为主,核心药物为石菖蒲、柴胡等,并常加用补益肝肾或行气活血或健脾养心或平肝潜阳药物。展开更多
基金National Natural Science Foundation of China,No.30171167,No.30901945Specialized Research Fund for the Doctoral Program of Higher Education,No.20130201130009+1 种基金Science and Technology Program of Shaanxi Province,No.2012KTCQ03-15Science Research Foundation of the Second Affiliated Hospital of Xi'an Jiaotong University,No.YJ(QN)201311)
文摘Acute pancreatitis(AP)is one of the most common diseases.AP is associated with significant morbidity and mortality,but it lacks specific and effective therapies.Traditional Chinese medicine(TCM)is one of the most popular complementary and alternative medicine modalities worldwide for the treatment of AP.The current evidence from basic research and clinical studies has shown that TCM has good therapeutic effects on AP.This review summarizes the widely used formulas,single herbs and monomers that are used to treat AP and the potential underlying mechanisms of TCM.Because of the abundance,low cost,and safety of TCM as well as its ability to target various aspects of the pathogenesis,TCM provides potential clinical benefits and a new avenue with tremendous potential for the future treatment of AP.
基金National key research plan(No.2018YFC1705303)Key research and development plan of Shanxi province(No.2019SF-312).
文摘Objective:To determine medication regularity external therapies of Traditional Chinese medicine of eczema by data mining.Methods:Papers were retrieved from databases Pubmed,CNKI,WF,VIP,CBM,Web of Science and Embase.From the establishment of the database to April 2020 were searched.The main points of Medication Regularity were established with Excel 2016 software;the characteristics and laws in external therapies of Traditional Chinese medicine Treatment of eczema were analyzed with the relevance rule and cluster analysis Methods in data mining technology.Results:The property and flavor of the herbs mainly used were cold,bitter,while the channel which are mostly involved included liver meridian,lung meridian and Bladder Meridian,The analysis of association rules showed that kushen and difuzi had the highest correlation.The clustering analysis figured out 7groups of the herbs.Conclusion:The study presents the common pair herbs in the treatment of external therapies of Traditional Chinese medicine of eczema,which provides the approach to syndrome differentiation and medication in clinical treatment of eczema.
文摘目的总结中药治疗耳鸣的核心方药及配伍规律。方法检索中国期刊全文数据库(CNKI)、PubMed、Web of Science等数据库中关于中药治疗耳鸣的临床研究文献。建立处方及药物信息数据库,统计药物频次及功效分类,并对其进行复杂网络分析。结果最终获取103首方剂,应用中药151味,总频次为1142次,涉及补虚药、活血化瘀药等17类药物。频次前3位中药为石菖蒲(63)、柴胡(45)、当归(42)。通过复杂网络分析得出,常用药对频次前3位为石菖蒲-丹参、石菖蒲-柴胡、石菖蒲-葛根,核心处方为石菖蒲、熟地黄、山萸肉、山药、柴胡、葛根、川芎、丹参、磁石。结论中药治疗耳鸣主要以益气升阳为主,核心药物为石菖蒲、柴胡等,并常加用补益肝肾或行气活血或健脾养心或平肝潜阳药物。
