Objective The aim of this study was to assess quality of results of elderly patients with coronary disease after medical or revascularisation therapy. Methods In this study, we enrolled 103 patients aged 75 years or o...Objective The aim of this study was to assess quality of results of elderly patients with coronary disease after medical or revascularisation therapy. Methods In this study, we enrolled 103 patients aged 75 years or older with chronic angina in which 47 patients were assigned coronary angiography and revascularisation and 56 patients with optimised medical therapy. The primary endpoint was quality of life after 6 months, as assessed by questionnaire and the presence of major adverse cardiac events (death, non fatal myocardial infarction, or hospital admission for acute coronary syndrome with or without the need for revascularisation). Results After 6 months follow up, angina severity decreased and measures of quality of life increased in both treatment groups( P <0.05 ); however, these improvements were significantly greater after revascularisation( P <0.01 ). Major adverse cardiac events occurred in 30 ( 53.6% ) of patients in the medical group and 9 ( 19.1% ) in the invasive group ( P <0.01 ).Conclusions Patients aged 75 years or older with angina benefit more from revascularisation than from optimised medical therapy in terms of symptom relief and quality of life. Therefore, these patients should be offered invasive assessment despite their high risk profile followed by revascularisation if feasible.展开更多
The very elderly patient population (＞80 years) represents a rapidly increasing segment of our demographics,a consequence of the longer life expectancy and aging of the 'baby boom' generation. Coronary artery...The very elderly patient population (＞80 years) represents a rapidly increasing segment of our demographics,a consequence of the longer life expectancy and aging of the 'baby boom' generation. Coronary artery disease remains a major cause of mortality and morbidity among octogenarians with an estimated 30% of them having symptomatic heart disease and 50% eventually dying from it.展开更多
Background Current guidelines for the treatment of ST-segment elevation myocardial infarction recommend a door-to-bal- loon time of 90 minutes or less for patients undergoing primary percutaneous coronary interventi...Background Current guidelines for the treatment of ST-segment elevation myocardial infarction recommend a door-to-bal- loon time of 90 minutes or less for patients undergoing primary percutaneous coronary intervention （PCI）. Door-to-balloon time has become a performance measure and is the focus of regional and national quality-im- provement initiatives. However, it is not known whether national improvements in door-to-balloon times have been accompanied by a decline in mortality.展开更多
文摘Objective The aim of this study was to assess quality of results of elderly patients with coronary disease after medical or revascularisation therapy. Methods In this study, we enrolled 103 patients aged 75 years or older with chronic angina in which 47 patients were assigned coronary angiography and revascularisation and 56 patients with optimised medical therapy. The primary endpoint was quality of life after 6 months, as assessed by questionnaire and the presence of major adverse cardiac events (death, non fatal myocardial infarction, or hospital admission for acute coronary syndrome with or without the need for revascularisation). Results After 6 months follow up, angina severity decreased and measures of quality of life increased in both treatment groups( P <0.05 ); however, these improvements were significantly greater after revascularisation( P <0.01 ). Major adverse cardiac events occurred in 30 ( 53.6% ) of patients in the medical group and 9 ( 19.1% ) in the invasive group ( P <0.01 ).Conclusions Patients aged 75 years or older with angina benefit more from revascularisation than from optimised medical therapy in terms of symptom relief and quality of life. Therefore, these patients should be offered invasive assessment despite their high risk profile followed by revascularisation if feasible.
文摘The very elderly patient population (＞80 years) represents a rapidly increasing segment of our demographics,a consequence of the longer life expectancy and aging of the 'baby boom' generation. Coronary artery disease remains a major cause of mortality and morbidity among octogenarians with an estimated 30% of them having symptomatic heart disease and 50% eventually dying from it.
基金Funded by the National Cardiovascular Data Registry of the American College of Cardiology Foundation
文摘Background Current guidelines for the treatment of ST-segment elevation myocardial infarction recommend a door-to-bal- loon time of 90 minutes or less for patients undergoing primary percutaneous coronary intervention （PCI）. Door-to-balloon time has become a performance measure and is the focus of regional and national quality-im- provement initiatives. However, it is not known whether national improvements in door-to-balloon times have been accompanied by a decline in mortality.
