Background The vasovagal reflex syndrome （VVRS） is common in the patiems undergoing percutaneous coronary intervemion （PCI） However, prediction and prevention of the risk for the VVRS have not been completely fulf...Background The vasovagal reflex syndrome （VVRS） is common in the patiems undergoing percutaneous coronary intervemion （PCI） However, prediction and prevention of the risk for the VVRS have not been completely fulfilled. This study was conducted to develop a Risk Prediction Score Model to identify the determinants of VVRS in a large Chinese population cohort receiving PCI. Methods From the hos- pital electronic medical database, we idemified 3550 patients who received PCI （78.0% males, mean age 60 years） in Chinese PLA General Hospital from January 1, 2000 to August 30, 2016. The multivariate analysis and receiver operating characteristic 01OC） analysis were performed. Results The adverse events of VVRS in the patients were significantly increased after PCI procedure than before the operation （all P 〈 0.001）. The rate of VVRS [95% confidence interval （CI）] in patients receiving PCI was 4.5% （4.1%-5.6%）. Compared to the patients suffering no VVRS, incidence of VVRS involved the following factors, namely female gender, primary PCI, hypertension, over two stems im- plantation in the left anterior descending （LAD）, and the femoral puncture site. The multivariate analysis suggested that they were independ- ent risk factors for predicting the incidence of VVRS （all P 〈 0.001）. We developed a risk prediction score model for VVRS. ROC analysis showed that the risk prediction score model was effectively predictive of the incidence of VVRS in patients receiving PCI （c-statistic 0.76, 95% CI： 0.72-0.79, P 〈 0.001）. There were decreased evems of VVRS in the patients receiving PCI whose diastolic blood pressure dropped by more than 30 mmHg and heart rate reduced by 10 times per minute （AUC： 0.84, 95% CI： 0.81-0.87, P 〈 0.001）. Conclusion The risk prediction score is quite efficient in predicting the incidence of VVRS in patients receiving PCI. In which, the following factors may be in- volved, the femoral puncture site, female gender, hypertension, primary PCI, and over 2 stents implanted in LAD.展开更多
Evaluating how park characteristics affect the formation of a park cool island(PCI) is the premise of guiding green parks planning in mountain cities.The diurnal variation of PCI intensity was achieved,and correlation...Evaluating how park characteristics affect the formation of a park cool island(PCI) is the premise of guiding green parks planning in mountain cities.The diurnal variation of PCI intensity was achieved,and correlations between PCI intensity and park characteristics such as park area,landscape shape index(LSI),green ratio and altitude were analyzed,using 3 010 temperature and humidity data from measurements in six parks with typical park characteristics in Chongqing,China.The results indicate that:1) the main factor determining PCI intensity is park area,which leads to obvious cool island effect when it exceeds 14 hm2;2) there is a negative correlation between PCI intensity and LSI,showing that the rounder the park shape is,the better the cool island effect could be achieved;3) regression analysis of humidity and PCI intensity proves that photosynthesis midday depression(PMD) is an important factor causing the low PCI intensity at 13:00;4) the multivariable linear regression model proposed here could effectively well predict the daily PCI intensity in mountain cities.展开更多
文摘Background The vasovagal reflex syndrome （VVRS） is common in the patiems undergoing percutaneous coronary intervemion （PCI） However, prediction and prevention of the risk for the VVRS have not been completely fulfilled. This study was conducted to develop a Risk Prediction Score Model to identify the determinants of VVRS in a large Chinese population cohort receiving PCI. Methods From the hos- pital electronic medical database, we idemified 3550 patients who received PCI （78.0% males, mean age 60 years） in Chinese PLA General Hospital from January 1, 2000 to August 30, 2016. The multivariate analysis and receiver operating characteristic 01OC） analysis were performed. Results The adverse events of VVRS in the patients were significantly increased after PCI procedure than before the operation （all P 〈 0.001）. The rate of VVRS [95% confidence interval （CI）] in patients receiving PCI was 4.5% （4.1%-5.6%）. Compared to the patients suffering no VVRS, incidence of VVRS involved the following factors, namely female gender, primary PCI, hypertension, over two stems im- plantation in the left anterior descending （LAD）, and the femoral puncture site. The multivariate analysis suggested that they were independ- ent risk factors for predicting the incidence of VVRS （all P 〈 0.001）. We developed a risk prediction score model for VVRS. ROC analysis showed that the risk prediction score model was effectively predictive of the incidence of VVRS in patients receiving PCI （c-statistic 0.76, 95% CI： 0.72-0.79, P 〈 0.001）. There were decreased evems of VVRS in the patients receiving PCI whose diastolic blood pressure dropped by more than 30 mmHg and heart rate reduced by 10 times per minute （AUC： 0.84, 95% CI： 0.81-0.87, P 〈 0.001）. Conclusion The risk prediction score is quite efficient in predicting the incidence of VVRS in patients receiving PCI. In which, the following factors may be in- volved, the femoral puncture site, female gender, hypertension, primary PCI, and over 2 stents implanted in LAD.
基金Project(2006BAJ02A02-05) supported by the National Key Technologies R&D Program of China
文摘Evaluating how park characteristics affect the formation of a park cool island(PCI) is the premise of guiding green parks planning in mountain cities.The diurnal variation of PCI intensity was achieved,and correlations between PCI intensity and park characteristics such as park area,landscape shape index(LSI),green ratio and altitude were analyzed,using 3 010 temperature and humidity data from measurements in six parks with typical park characteristics in Chongqing,China.The results indicate that:1) the main factor determining PCI intensity is park area,which leads to obvious cool island effect when it exceeds 14 hm2;2) there is a negative correlation between PCI intensity and LSI,showing that the rounder the park shape is,the better the cool island effect could be achieved;3) regression analysis of humidity and PCI intensity proves that photosynthesis midday depression(PMD) is an important factor causing the low PCI intensity at 13:00;4) the multivariable linear regression model proposed here could effectively well predict the daily PCI intensity in mountain cities.
