The integration of photovoltaic,energy storage,direct current,and flexible load(PEDF)technologies in building power systems is an importantmeans to address the energy crisis and promote the development of green buildi...The integration of photovoltaic,energy storage,direct current,and flexible load(PEDF)technologies in building power systems is an importantmeans to address the energy crisis and promote the development of green buildings.The friendly interaction between the PEDF systems and the power grid can promote the utilization of renewable energy and enhance the stability of the power grid.For this purpose,this work introduces a framework of multiple incentive mechanisms for a PEDF park,a building energy system that implements PEDF technologies.The incentive mechanisms proposed in this paper include both economic and noneconomic aspects,which is the most significant innovation of this paper.By modeling the relationship between a PEDF park and the power grid into a Stackelberg game,we demonstrate the effectiveness of these incentive measures in promoting the friendly interaction between the two entities.In this game model,the power grid determines on the prices of electricity trading and incentive subsidy,aiming to maximize its revenue while reducing the peak load of the PEDF park.On the other hand,the PEDF park make its dispatch plan according to the prices established by the grid,in order to reduce electricity consumption expense,improve electricity utility,and enhance the penetration rate of renewable energy.The results show that the proposed incentive mechanisms for the PEDF park can help to optimize energy consumption and promote sustainable energy practices.展开更多
【目的】研究色素上皮衍生因子PEDF表达水平与脂代谢的关系,探讨PEDF参与血脂代谢的可能调控机制,为揭示PEDF参与多种代谢疾病提供重要依据。【方法】应用Crispr/Cas9基因修饰技术构建PEDF-/-小鼠,高脂饮食(HFD)诱导肥胖小鼠模型,检测...【目的】研究色素上皮衍生因子PEDF表达水平与脂代谢的关系,探讨PEDF参与血脂代谢的可能调控机制,为揭示PEDF参与多种代谢疾病提供重要依据。【方法】应用Crispr/Cas9基因修饰技术构建PEDF-/-小鼠,高脂饮食(HFD)诱导肥胖小鼠模型,检测小鼠血脂水平(甘油三脂TG、总胆固醇TC、游离脂肪酸FFAs)的变化,实时定量RT-PCR检测脂肪组织中脂肪代谢关键基因(ATGL、PPAR-γ、FAS、HSL)的表达量。【结果】基因组水平鉴定和蛋白水平检测表明PEDF-/-小鼠构建成功;HFD诱导肥胖后,野生型(WT)小鼠体重增加百分比、内脏脂肪及血脂水平均比正常饮食组(CD)的高(P<0.05),差异均具有统计学意义,说明肥胖模型构建成功,而PEDF-/-组小鼠HFD后体重增加百比、内脏脂肪和血脂水平高于CD组(P<0.05),高于WT小鼠的HFD组(P<0.05);实时定量RT-PCR结果显示,WT小鼠HFD后ATGL、PPAR-γ和FAS转录水平都比CD组低(P<0.05),HSL m RNA水平无明显差别;而PEDF敲除后,ATGL、PPAR-γ和HSL转录水平较WT组的显著下调(P<0.01),而FAS水平CD组明显升高,HFD组显著下调;PEDF敲除后,HFD组ATGL m RNA水平高于CD组,PPAR-γ和HSL m RNA水平低于CD组。【结论】成功构建PEDF基因敲除小鼠;PEDF可能通过ATGL、PPAR-γ和HSL促进了脂肪分解,通过FAS抑制脂肪酸合成,从而参与了肥胖小鼠的血脂代谢及内脏脂肪沉积。展开更多
基金supported by Guangxi Power Grid Science and Technology Project(GXKJXM20222069).
文摘The integration of photovoltaic,energy storage,direct current,and flexible load(PEDF)technologies in building power systems is an importantmeans to address the energy crisis and promote the development of green buildings.The friendly interaction between the PEDF systems and the power grid can promote the utilization of renewable energy and enhance the stability of the power grid.For this purpose,this work introduces a framework of multiple incentive mechanisms for a PEDF park,a building energy system that implements PEDF technologies.The incentive mechanisms proposed in this paper include both economic and noneconomic aspects,which is the most significant innovation of this paper.By modeling the relationship between a PEDF park and the power grid into a Stackelberg game,we demonstrate the effectiveness of these incentive measures in promoting the friendly interaction between the two entities.In this game model,the power grid determines on the prices of electricity trading and incentive subsidy,aiming to maximize its revenue while reducing the peak load of the PEDF park.On the other hand,the PEDF park make its dispatch plan according to the prices established by the grid,in order to reduce electricity consumption expense,improve electricity utility,and enhance the penetration rate of renewable energy.The results show that the proposed incentive mechanisms for the PEDF park can help to optimize energy consumption and promote sustainable energy practices.
文摘【目的】研究色素上皮衍生因子PEDF表达水平与脂代谢的关系,探讨PEDF参与血脂代谢的可能调控机制,为揭示PEDF参与多种代谢疾病提供重要依据。【方法】应用Crispr/Cas9基因修饰技术构建PEDF-/-小鼠,高脂饮食(HFD)诱导肥胖小鼠模型,检测小鼠血脂水平(甘油三脂TG、总胆固醇TC、游离脂肪酸FFAs)的变化,实时定量RT-PCR检测脂肪组织中脂肪代谢关键基因(ATGL、PPAR-γ、FAS、HSL)的表达量。【结果】基因组水平鉴定和蛋白水平检测表明PEDF-/-小鼠构建成功;HFD诱导肥胖后,野生型(WT)小鼠体重增加百分比、内脏脂肪及血脂水平均比正常饮食组(CD)的高(P<0.05),差异均具有统计学意义,说明肥胖模型构建成功,而PEDF-/-组小鼠HFD后体重增加百比、内脏脂肪和血脂水平高于CD组(P<0.05),高于WT小鼠的HFD组(P<0.05);实时定量RT-PCR结果显示,WT小鼠HFD后ATGL、PPAR-γ和FAS转录水平都比CD组低(P<0.05),HSL m RNA水平无明显差别;而PEDF敲除后,ATGL、PPAR-γ和HSL转录水平较WT组的显著下调(P<0.01),而FAS水平CD组明显升高,HFD组显著下调;PEDF敲除后,HFD组ATGL m RNA水平高于CD组,PPAR-γ和HSL m RNA水平低于CD组。【结论】成功构建PEDF基因敲除小鼠;PEDF可能通过ATGL、PPAR-γ和HSL促进了脂肪分解,通过FAS抑制脂肪酸合成,从而参与了肥胖小鼠的血脂代谢及内脏脂肪沉积。
