Injectable nanoparticle carrier, poly(ethylene glycol)-coated poly(ethyl cyanoacrylate) has been prepared by a simple method. At First, synthesizing PEG macromonomer of poly(ethylene glycol) monomethyl ether with acry...Injectable nanoparticle carrier, poly(ethylene glycol)-coated poly(ethyl cyanoacrylate) has been prepared by a simple method. At First, synthesizing PEG macromonomer of poly(ethylene glycol) monomethyl ether with acryloyl chloride, then graft copolymer of poly(ethyl cyanoacrylate) and poly(ethylene glycol) was yield by free radical polymerization of ethyl cyanoacrylate with PEG macromonomer in toluene solvent. Characterization of the copolymer has been performed by FTIR, 1 H-NMR and GPC analysis. Nanoparticles were easily prepared from the obtained amphiphilic copolymer.展开更多
文摘Injectable nanoparticle carrier, poly(ethylene glycol)-coated poly(ethyl cyanoacrylate) has been prepared by a simple method. At First, synthesizing PEG macromonomer of poly(ethylene glycol) monomethyl ether with acryloyl chloride, then graft copolymer of poly(ethyl cyanoacrylate) and poly(ethylene glycol) was yield by free radical polymerization of ethyl cyanoacrylate with PEG macromonomer in toluene solvent. Characterization of the copolymer has been performed by FTIR, 1 H-NMR and GPC analysis. Nanoparticles were easily prepared from the obtained amphiphilic copolymer.