CLINICAL OBSERVATION OF THE THERAPEUTICAL EFFECT OF 32 CASES OF ACUTE AND CHRONIC CHOLECYSTITIS WITH EYE ACUPUNCTURE

32 cases of patients with acute and chronic cholecystitis were treated with eyeacupuncture.The eye points used were Liver Region,Gallbladder Region and Middle Jiao Region.Reinforcing or reducing technique were applied under different conditions,The cure rate was 25％,the markedly effective rate was 31.25％,the effective rate was 28.21％and the ineffective rate was15.6％.The total effective rate was 84.37％.

Clinical Observation on Treatment of Sequelae of Apoplexy With Eye and Body Acupuncture

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Effects of different acupuncture methods combined with routine rehabilitation on gait of stroke patients

BACKGROUND Stroke refers to a group of cerebrovascular diseases associated with organic braininjury. It is characterized by the sudden and rapid onset of focal or diffusedysfunction. In recent years, in addition to routine treatment, Chinese medicineacupuncture has been administered to patients with hemiplegia, and it can beconsidered a new treatment for rehabilitation.AIM To investigate the effects of eye acupuncture needle retention and bodyacupuncture combined with routine rehabilitation on gait performance andplantar pressure in patients recovering from stroke.METHODS Thirty-two stroke patients who met the inclusion criteria were randomly dividedinto an experimental group and a control group, with 16 patients in each group.Both groups underwent routine rehabilitation. The experimental group wastreated by eye acupuncture needle retention, and the control group was treated bybody acupuncture. Before and after 4 wk of treatment, both groups underwentkinematic and plantar pressure synchronous tests to assess gait performance.RESULTS The step length, gait speed, step frequency, joint angles of the lower limbs, andground reaction force impulse in the anterior region of the affected foot in bothgroups significantly increased from before to after treatment (P < 0.05);the center of mass displacement, peak pressure values, and impulse in the anterior region ofthe healthy foot and posterior regions of both the affected and healthy feetsignificantly decreased from before to after treatment (P < 0.05). The patients inthe experimental group showed greater improvement in the following parametersthan the control group: Step length, gait speed, step frequency, lower extremityjoint angles, center of gravity displacement, and peak pressure values andimpulse in the anterior and posterior regions of both the affected and healthy feet(P < 0.05).CONCLUSION Eye acupuncture needle retention and body acupuncture combined with routinerehabilitation can effectively improve the gait performance of patients recoveringfrom stroke. Between these two treatments, eye acupuncture needle retentioncombined with routine treatment is better than body acupuncture, and it can beconsidered a practical and effective clinical treatment.

彭旭明分筋推拿结合恢刺法治疗前斜角肌综合征经验

前斜角肌综合征(SAS)是临床常见脊柱相关疾病,彭旭明教授认为,SAS病位在颈肩,以筋骨失衡为发病基础,筋挛成结为病机关键,治疗以“祛瘀通经”“舒筋缓急”“疏解筋结”“筋骨同调”为总治则,应用恢刺、彭氏分筋推拿调整颈部筋骨关系,达到筋柔骨正的良好状态,其改良的“扶持一指禅手法”在分筋解除粘连组织中发挥重要作用。附医案一则,以飨同道。

Effect of eye acupuncture on the expression of brainderived neurotrophic factor in hippocampus in rats with cerebral ischemia-reperfusion injury

Objective To observe the effects of eye acupuncture on expression of brain-derived neurotrophic factor （BDNF） in the hippocampus of rats after ischemia- reperfusion injury in order to study the mechanisms of eye acupuncture in improving ischemia-reperfusion injury. Methods SD rats were randomly divided into a normal group, a sham-operation group, a model group and an eye acupuncture group, with 8 rats in each. The cerebral ischemia-reperfusion injury model was established by thread occlusion method. Acupuncture at ＂liver＂, ＂upper-jiao＂, ＂lower-jiao＂, and ＂kidney＂ was performed for 20 min in the eye acupuncture group immediateness, 12 h and 23.5 h after the reperfusion. After 24 h of the reperfusion, the neurophysical behaviors were evaluated by Zea Longa neurophysical impairment score; the expression of ischemic hippocampus BDNF mRNA was measured by RT-PCR; the expression of ischemic hippocampus BDNF protein was detected by Western blot technique. Results After reperfusion 24 h, compared with the model group, the neurologic impairment score of the eye acupuncture group decreased significantly （P〈0.01）; the expressions of BDNF mRNA and protein in rat hippocampi after the eye acupuncture therapy were both obviously increased （P〈0.01）. Conclusion The eye acupuncture therapy is beneficial for neurofunctional rehabilitation by promoting the repair of the nerve cell which is induced by increasing hippocampus BDNF expression.

Effect of eye acupuncture on plasma PGF_(2α) in patients of primary dysmenorrhea

Objective To observe the clinical curative effect of eye acupuncture therapy on primary dysmenorrhea and the effect on content of prostaglandin F2α （PGF2α） in peripheral blood of menstrual periods. Methods One hundred and ten cases of primary dysmenorrhea were randomly divided into an eye acupuncture group （60 cases） and a medication group （50 cases）. In the eye acupuncture group, lower-jiao area, liver area, kidney area, heart area and spleen area, etc. were selected according to syndrome differentiation, and the eye acupuncture therapy was applied. In the medication group, 300 mg Ibuprofen sustained release capsule was orally administrated 1–2 days before menstrual onset or when the symptoms appeared, once every 12 hours, for 3–5 days totally, 3 menstrual periods constituting one therapeutic course. The content of PGF2α in peripheral blood, and the curative effects and recurrence 3 and 6 months after treatment were observed. Results Three months after treatment, the cured rate was 55.0% （33/60） and the total effective rate was 95.0% （57/60） in the eye acupuncture group, which were superior to those of 34.0% （17/50） and 82.0% （41/50） in the medication group （both P0.05）. According to the following-up after 6 menstrual cycles, the recurrence rate of 9.1% （3/33） in the acupuncture group was significantly lower than that of 35.3% （6/11） in medication group. The contents of PGF2α in peripheral blood of menstrual periods were reduced after treatment in the two groups （both P0.01）. Conclusion The curative effect of eye acupuncture on primary dysmenorrhea is significant, with the level of PGF2α in peripheral blood of menstrual periods reduced.

彭氏眼针学术思想发微

辽宁彭氏眼针起源于20世纪70年代,是彭静山教授通过对万人白睛络脉的观察,结合数十载的临证经验而独创的诊疗体系,包括“观眼识病”望诊法与针刺眼周穴位的“眼针疗法”。彭氏眼针经过半个多世纪的蓬勃发展,形成了以“眼针八区十三穴络脑通脏腑”为核心的学术体系。通过对彭氏眼针学术思想的挖掘、梳理、总结,达到完善学术内容,传承流派精华,推动技术创新之目的。

彭静山眼针“八区十三穴络脑通脏腑”理论

辽宁彭氏眼针学术流派宗师彭静山教授首创“眼针疗法”,其理论源于王肯堂《证治准绳·目门》记载的眼与脏腑关系及五轮八廓学说。彭静山嫡传弟子王鹏琴教授通过国家973课题及多年临床研究,总结挖掘眼针疗法理论为“眼针八区十三穴络脑通脏腑”,眼-经络-脑-脏腑紧密联系,眼针通过针刺眼眶周围特定穴位治疗全身疾病,应用于临床治疗疾病40余年,临床疗效确切,中风病及痛症为其优势病种。文章深入探讨分析眼针疗法核心理论,挖掘整理本流派学术思想体系,传承发展流派核心技术。

周鹏“调神固本”法治疗癌因性疲乏经验

周鹏教授认为癌因性疲乏区别于传统认知的虚劳,不仅形体大损,神气亦大伤。治疗上当以“调神固本”思想为指导,调气机以调神,补脾肾以固本,从形神上共治癌因性疲乏。临床上采用多维外治的治疗模式,具体以单纯针刺和精灸为治疗基础,辨证灵活选用浮针、耳针、刺络拔罐等外治法。临证选穴重视原穴、任督脉穴与足三阴经穴的配伍使用,共奏调神固本之功,可有效改善癌因性疲乏患者的疲乏症状。

周鹏基于调神固本思想论治慢性五官疾病

慢性五官疾病是五官疾病中的疑难点,相较于急性五官病证,其病情复杂、病程缠绵、难以根治且多伴有情志病变。周鹏教授基于“整合针灸”思维提出“调神固本思想”,从心、脾、肾论治慢性五官疾病,选用督脉、心经、脾经、肾经相关腧穴配合,调心神、脑神以司五官之神,养脾肾以固五官之形,在临床上疗效显著,对扩展五官病的临床辨治具有重要的指导意义。

Influence of electroacupuncture on histomorphology of lacrimal glands and ocular surface in experimental dry eye syndrome

Objective： To observe the influence of electroacupuncture （EA） on histomorphologies of lacrimal glands, cornea and conjunctiva in experimental dry eye syndrome, and to explore the repair effects of EA on lacrimal glands and ocular surface damage. Methods： Twenty-four healthy male New Zealand rabbits were randomly divided into a normal group, a model group, an EA group and a medication group, 6 rabbits in each group. Experimental dry eye syndrome models were prepared in rabbits by using 0.1% benzalkonium chloride for eye drops. Tear secretion volume, break-up time of tear film （BUT） and corneal fluorescein staining score were observed before and after the treatment. Periodic acid Schiff （PAS） staining method was used to observe the changes of conjunctival goblet cells in rabbits. After hematoxylin eosin （HE） staining, morphological changes of rabbit cornea, conjunctiva and lacrimal gland tissues were observed under light microscope. Results： Compared with the normal group, tear secretion volume and BUT were significantly reduced （both P^0.01）, while the corneal fluorescein staining score was significantly increased （P〈O.01） in the model group. Compared with the model group, tear secretion volume and BUT were significantly increased, while the corneal fluorescein staining score was significantly decreased in the EA group and the medication group （all P〈0.01）. Compared with the normal group, the number of conjunctival goblet cells in the model group was significantly reduced; compared with the model group, the numbers of conjunctival goblet cells were all relatively higher in the EA group and the medication group. Pathological lesions of cornea, conjunctiva and lacrimal glands all showed improvement by HE staining in the EA group and the medication group after the intervention. Conclusion： EA can improve tear secretion and tear film stability of rabbit dry eye syndrome, and repair the pathologic lesions of conjunctival goblet cells, corneal epithelia, cornea, conjunctiva and lacrimal glands.

Effects of dry eye syndrome and tear film mucin treated with acupuncture

Objective To explore the therapeutic effects and mechanism of dry eye syndrome treated with acupuncture therapy. Methods Thirty cases （60 eyes） of dry eye syndrome were treated with both local and distal acupuncture. Jingrning （睛明 BL 1）, Cuanzhu （攒竹 BL 2）, Tatiyang （太阳 EX-HN 5） and Quchi （曲池 LI 11） were selected; tear secretion quantity, break up time of tear film （BUT） and expression of tear film mucin were observed before and after treatment. Results Tear secretion quantity was increased and break up time of tear film was prolonged after acupuncture therapy, indicating the significant differences （both P〈0.05）; meanwhile, the expression of tear film mucin was increased [（0.67 ± 0.1） ng vs （0.89 ± 0.23） ng, P〈0.05]. Conclusion Acupuncture can promote the expression of tear film mucin, enhance the stability of tear film and remarkably improve the symptoms of dry eye.

Summary on Clinical Experience of Acupuncture Treating Dry Eye Syndromes

Dry eye syndromes （DES） refer to discomfort in the eye region, visual disturbance, poor stability of lacrimal film, inflammation of eye surface and its potential injury due to many factors of abnormal lacrimation. Patients with this condition can experience a dry sensation in the eyes, foreign body sensation,

Effects of electroacupuncture on conjunctival cell apoptosis and the expressions of apoptosis-related proteins Caspase-3,Fas and Bcl-2 in rabbits with dry eye syndrome

Objective:By observing the effects of electroacupuncture(EA)on the apoptosis of conjunctival cells of rabbits with dry eye syndrome(DES)and the expressions of apoptosis-related proteins Caspase-3,Fas and Bcl-2,to discuss the mechanism of EA in the treatment of DES from the perspective of cell apoptosis.Methods:Male New Zealand rabbits were randomly divided into a normal group(NG),a model group(MG),an EA group(EAG)and a sham EA group(SEAG).DES rabbit model was developed by eye drop of 0.1%benzalkonium chloride.The rabbit tear secretion and tear film break-up time(BUT)were measured;terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling(TUNEL)assay was used to detect the apoptosis of conjunctival cells;the expressions of Caspase-3,Fas and Bcl-2 proteins in conjunctival cells were detected by immunohistochemistry.Results:Compared with the NG,the rabbit tear secretion decreased and the BUT was shortened in the MG(both P<0.01);compared with the MG and the SEAG,the rabbit tear secretion increased and the BUT was prolonged in the EAG(all P<0.05).Compared with the NG,the apoptosis of rabbit conjunctival cells increased(P<0.01),the expressions of Caspase-3 and Fas proteins increased(both P<0.05),and the expression of Bcl-2 protein decreased(P<0.01)in the MG;compared with the MG and the SEAG,the apoptosis of rabbit conjunctival cells decreased(both P<0.01),the expressions of Caspase-3 and Fas proteins decreased(all P<0.05),and the expression of Bcl-2 protein increased(both P<0.01)in the EAG.Conclusion:EA can inhibit the apoptosis of rabbit conjunctival cells,down-regulate the expressions of apoptosis-related proteins Caspase-3 and Fas,and up-regulate the expression of Bcl-2 protein,which may be one of the mechanisms of EA in treatment of DES.

Efficacy observation of acupuncture for dry eye syndrome of lung-yin deficiency pattern

Objective:To observe the clinical efficacy of combining two needling manipulations,Er Long Xi Zhu(two dragons playing with a pearl)and Guo Yan Re(heat produced to reach the eyes),in treating dry eye syndrome(DES)of lung-yin deficiency pattern.Methods:Fifty-six eligible DES patients of lung-yin deficiency were randomized into an observation group and a control group,with 28 cases in each group.Same acupoints were selected in the two groups:Cuanzhu(BL 2),Sizhukong(TE 23),Taiyang(EX-HN 5)and Fengchi(GB 20)were chosen as the major points and Feishu(BL 13)and Chize(LU 5)as the adjuvant.Er Long Xi Zhu and Guo Yan Re needling manipulations were applied in the observation group while twirling reinforcing manipulation was used in the control group.Treatment was conducted once per day in both groups,for two sets of 15 consecutive days at a 2-day interval.Changes in the symptom score,tear break-up time(BUT)and tear production were observed afterwards,and the clinical efficacy was also compared between the two groups.Results:The total effective rate was 92.8%in the observation group,higher than 71.4%in the control group,and the between-group difference was statistically significant(P<0.05).After treatment,the symptom score,tear BUT and tear production showed significant improvements in both groups(all P<0.05);the symptom score,BUT and tear production in the observation group were significantly different from those in the control group(all P<0.05).Conclusion:Given the same acupoint selection,combining Er Long Xi Zhu and Guo Yan Re needling manipulations can produce more significant clinical efficacy than twirling reinforcing manipulation in treating DES of lung-yin deficiency pattern.

Acupuncture for dry eye syndrome:a meta-analysis of randomized controlled trials

Objective： To summarize and critically assess the evidence from randomized controlled trials（RCTs） of acupuncture in treating dry eye syndrome（DES） according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses（PRISMA） statement and the Cochrane Collaboration recommendations.Methods： A search of PubMed, the Cochrane Central Register of Controlled Trials, ClinicalTrials.gov and Embase was made from their inception to August 2016, as well as Chinese, Japanese, and Korean databases. Two reviewers independently selected RCTs and assessed the methodological quality. Meta-analysis and the level of evidence were processed by RevMan 5.3 and the Grading of Recommendations Assessment, Development and Evaluation（GRADE）approach.Results： After selection, 8 trials were subjected to our systematic review. The methodological quality was low generally.The 3-10 weeks follow-up showed that acupuncture improved the tear film break-up time（BUT）（MD=1.33, 95%CI=1.01-1.66, 619 participants）. The mean difference of Schirmer＇s test was 1.73 mm（95%CI=1.28-2.18, 618participants） between the acupuncture group and the control group. The subjective variables exhibited no significant differences.Conclusion： The low methodological quality of the trials does not suggest drawing firm conclusions on the value of acupuncture therapy for DES. Acupuncture treatment may have some effects on the tear film BUT and Schirmer＇s test,but not on the subjective symptoms. Well-planned large-scale high-quality RCTs are needed to make it clear whether acupuncture is effective in treating DES.

Case of eye acupuncture combined with body acupuncture in treatment of knee arthritis

The patient was diagnosed as knee osteoarthritis. She was treated with eye acupuncture at both kidneys, bladder, and lower jiao combined with body acupuncture bilateral Xīyǎn（膝眼 EX-LE 5）, Yánglíngquán（阳陵泉 GB 34）, Yīnlíngquán（阴陵泉 SP 9）, Zúsānlǐ（足三里 ST 36） and Hèdǐng（鹤顶 EX-LE 2）. The patient was cured after 10 times of treatment and pain was not found during follow-up visit for one month. The combination use of eye acupuncture and body acupuncture in treatment of this case of knee arthritis obtained good efficacy, which is worthy of clinical popularization and application.

Acupuncture for the management of dry eye disease

The effectiveness of using acupuncture for dry eye disease(DED)is controversial.Thus,this systematic review investigated the effectiveness and feasibility of using acupuncture for DED in accordance with the 2020 PRISMA statement.The outcomes of interests were(1)to evaluate the efficacy of acupuncture in improving the ocular surface disease index(OSDI),Schirmer I test score,and tear breakup time from baseline to the last follow-up;(2)to determine possible complications of using acupuncture;and(3)to investigate the superiority of acupuncture over other commonly used treatments for DED.Data from 394 patients were collected.Results showed that acupuncture significantly prolonged the tear breakup time(P<0.0001),significantly increased the Schirmer I test score(P<0.0001),and significantly reduced the OSDI(P<0.0001)from baseline to the last follow-up.Compared with the control group,the acupuncture group had significantly greater Schirmer I test score(P<0.0001),significantly longer tear breakup time(P=0.0004),and significantly lower OSDI(P=0.002).These results suggest that acupuncture is effective and feasible in improving symptoms and signs of DED.No severe adverse effects of acupuncture were observed.

Research on Acupuncture-moxibustion for Dry Eye Syndrome

Dry eye syndrome （DES） is a commonly encountered ophthalmological disease, with a relatively high incidence, and expects an effective treatment method. Acupunctureoxibustion therapy promotes tear production of lacrimal gland without causing a trauma, and thus has a great advantage in treating DES. Through literature analysis, this article summarized the research progress in both clinical practice and mechanism of acupuncture- moxibustion in treating DES during the recent 10 years, for providing valuable references for the application of acupuncture-moxibustion for DES.

Efficacy of electroacupuncture for patients with dry eye syndromes:a randomized controlled trial

Objective To observe the efficacy of electroacupuncture(EA)in treating dry eye syndromes(DES)and its regulatory effects on patient’s quality of life(QOL),anxiety,and depression.MethodsBy following a randomized controlled study design,eligible DES patients were allocated to an EA group(EAG)or an acupuncture group(AG).Patients in the AG were intervened by acupuncture alone,while in the EAG,electrical stimulation was applied to Cuanzhu(BL2)and Taiyang(EX-HN5)in addition to the same treatment in the AG.Changes in clinical manifestations,ocular surface disease index(OSDI),Schirmer tear test-1(STT-1),tear-film break-up time(TF-BUT),cornea fluorescein staining(CFS),and corneal sensitivity(CS)were observed,as well as changes in the short-form 36-item health survey(SF-36)and hospital anxiety and depression scale(HADS)scores.ResultsThe scores of clinical symptoms,OSDI,and CFS decreased significantly in both EAG and AG when compared with the baseline values(P<0.05),respectively,while the TF-BUT and CS increased significantly(P<0.05),and the tear secretion of patients in the EAG increased(P<0.05).Compared with those before treatment,the scores of physical role functioning,general health perception,emotional role functioning,and mental health of patients in both EAG and AG showed significant increases after treatment(P<0.05),together with a marked decrease in the score of anxiety(P<0.05).Compared with the AG,the EAG obtained a more significant increase in STT-1(P<0.05).ConclusionDES patients respond well to both EA and acupuncture treatments,manifested by prolonged TF-BUT and improvement of CS.Meanwhile,the two approaches can improve QOL and reduce anxiety.Furthermore,EA appears more effective in increasing tear secretion than acupuncture alone.