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Surgical Management of Perforated Colon Tumours in Yaoundé: A Multicentre Retrospective Review of 30-Day Postoperative Outcome
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作者 Eric Patrick Savom Richard II Mbele +6 位作者 Colman Tamboh Tankou Mahamat Yannick Ekani Boukar Cédric Paterson Atangana Fred Dikongue Dikongue Daniel Biwole Biwole Guy Aristide Bang Arthur Essomba 《Surgical Science》 2024年第5期330-341,共12页
Introduction: Colon cancer is often diagnosed late in our context and there is a high prevalence of complicated forms, this including perforation. The optimal surgical treatment remains controversial. The aim of this ... Introduction: Colon cancer is often diagnosed late in our context and there is a high prevalence of complicated forms, this including perforation. The optimal surgical treatment remains controversial. The aim of this study was to improve the short-term postoperative outcomes of patients operated upon for perforated colon cancer, by identifying factors associated with complications occurring within 30 days after surgery. Patients and methods: We carried out an analytical observational study, with a retrospective collection of data from the files of patients operated upon for an in situ tumoral colon perforation. This was done in four referral hospitals in the city of Yaoundé. The period was from the 1<sup>st</sup> of January, 2012 to the 31<sup>st</sup> of December, 2021. Cox regression identified the factors associated with postoperative morbidity and mortality. Results: We collected files of 46 patients. The mean age was 54.7 ± 19.9 years with a sex ratio of 1.4. The clinical presentation on admission was dominated by the presence of signs of peritoneal irritation (91.3%) and bowel obstruction (28.3%). The diagnosis was made preoperatively in 16 cases (34.8%). The surgical procedures consisted of colectomy with anastomosis in 28 cases (60.9%) and without anastomosis in 14 cases (30.4%). Postoperative morbidity was 60.9% dominated by surgical site infection (37%). Postoperative mortality was 39.1%. The existence of generalized peritonitis was associated with the occurrence of postoperative complications (p = 0.019). The main factors associated with postoperative mortality were resection with primary anastomosis (p = 0.027), enterocutaneous fistula (p = 0.005). Conclusion: Colic resection with primary anastomosis or ideal colectomy is associated with an increased risk of mortality and should therefore not be performed in this setting. 展开更多
关键词 perforated Colon Cancer Postoperative Morbidity and Mortality COLECTOMY Acute Generalized Peritonitis
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Perforated gastric ulcer causing mediastinal emphysema: A case report
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作者 Zhi-Cheng Dai Xun-Wu Gui +2 位作者 Feng-He Yang Hao-Yuan Zhang Wen-Feng Zhang 《World Journal of Clinical Cases》 SCIE 2024年第4期859-864,共6页
BACKGROUND Mediastinal emphysema is a condition in which air enters the mediastinum between the connective tissue spaces within the pleura for a variety of reasons.It can be spontaneous or secondary to chest trauma,es... BACKGROUND Mediastinal emphysema is a condition in which air enters the mediastinum between the connective tissue spaces within the pleura for a variety of reasons.It can be spontaneous or secondary to chest trauma,esophageal perforation,medi-cally induced factors,etc.Its common symptoms are chest pain,tightness in the chest,and respiratory distress.Most mediastinal emphysema patients have mild symptoms,but severe mediastinal emphysema can cause respiratory and circulatory failure,resulting in serious consequences.CASE SUMMARY A 75-year-old man,living alone,presented with sudden onset of severe epigastric pain with chest tightness after drinking alcohol.Due to the remoteness of his residence and lack of neighbors,the patient was found by his nephew and brought to the hospital the next morning after the disease onset.Computed tomography(CT)showed free gas in the abdominal cavity,mediastinal emph-ysema,and subcutaneous pneumothorax.Upper gastrointestinal angiography showed that the esophageal mucosa was intact and the gastric antrum was perforated.Therefore,we chose to perform open gastric perforation repair on the patient under thoracic epidural anesthesia combined with intravenous anesthesia.An operative incision of the muscle layer of the patient's abdominal wall was made,and a large amount of subperitoneal gas was revealed.And a continued incision of the peritoneum revealed the presence of a perforation of approx-imately 0.5 cm in the gastric antrum,which we repaired after pathological examination.Postoperatively,the patient received high-flow oxygen and cough exercises.Chest CT was performed on the first and sixth postoperative days,and the mediastinal and subcutaneous gas was gradually reduced.CONCLUSION After gastric perforation,a large amount of free gas in the abdominal cavity can reach the mediastinum through the loose connective tissue at the esophageal hiatus of the diaphragm,and upper gastrointestinal angiography can clarify the site of perforation.In patients with mediastinal emphysema,open surgery avoids the elevation of the diaphragm caused by pneumoperitoneum compared to laparoscopic surgery and avoids increasing the mediastinal pressure.In addition,thoracic epidural anesthesia combined with intravenous anesthesia also avoids pressure on the mediastinum from mechanical ventilation. 展开更多
关键词 Gastric ulcer perforated Mediastinal emphysema Case report
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Clinical Epidemiology and Surgical Treatment of Spontaneous Perforations of the Terminal Ileum: A Multicentre Study in Cameroon
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作者 Eric Patrick Savom Richard II Mbele +5 位作者 Mahamat Yannick Ekani Boukar Abdal Deudeu Cédric Paterson Atangana Fred Dikongue Dikongue Guy Aristide Bang Marc Leroy Guifo 《Surgical Science》 2024年第5期311-320,共10页
Background: Perforations of the terminal ileum are a frequent clinical situation and a therapeutic challenge. Surgical treatment is controversial. Several surgical modalities have been proposed and postoperative morbi... Background: Perforations of the terminal ileum are a frequent clinical situation and a therapeutic challenge. Surgical treatment is controversial. Several surgical modalities have been proposed and postoperative morbidity and mortality remain high. The aim of this study was to review our experience in the surgical management of perforations of the terminal ileum. Patients and methods: This is a descriptive cross-sectional study with retrospective data collection from January 1, 2017 to December 31, 2021, in five hospitals in Cameroon. Patients’ demographic, clinical presentation, surgical findings and 30-days postoperative outcomes data were collected. Results: We collected 34 files. The sex ratio was 1.4 and the average age was 20.28 years. The average consultation time was 9.1 days. Abdominal pain was present in all our patients. Peritoneal irritation was present in 46 cases (88.5%). The mean time to treatment after admission was 17.5 hours. The perforation was unique in 40 cases (76.9%) and located between 6 and 10 cm from the ileocecal valve in 29 cases (55.8%). Typhoid was the most suspected etiology intraoperatively in 38 cases (73.1%). A simple suture was performed in 18 patients (34.6%), resection with anastomosis in 11 patients (21.2%) and an ileostomy in 5 patients (9.6%). The average length of hospitalization was 21.74 days. Postoperative morbidity and mortality were 32.7% and 17.3% respectively. Conclusion: Perforations of the terminal ileum are common and affect young people. Surgical procedures are varied. Reducing consultation and care times and respecting treatment principles could improve postoperative morbidity and mortality, which remain high. 展开更多
关键词 perforation of the Terminal Ileum Simple Suture RESECTION MORBIDITY MORTALITY
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Productivity Prediction Model of Perforated Horizontal Well Based on Permeability Calculation in Near-Well High Permeability Reservoir Area
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作者 Shuangshuang Zhang Kangliang Guo +3 位作者 Xinchen Gao Haoran Yang Jinfeng Zhang Xing Han 《Energy Engineering》 EI 2024年第1期59-75,共17页
To improve the productivity of oil wells,perforation technology is usually used to improve the productivity of horizontal wells in oilfield exploitation.After the perforation operation,the perforation channel around t... To improve the productivity of oil wells,perforation technology is usually used to improve the productivity of horizontal wells in oilfield exploitation.After the perforation operation,the perforation channel around the wellbore will form a near-well high-permeability reservoir area with the penetration depth as the radius,that is,the formation has different permeability characteristics with the perforation depth as the dividing line.Generally,the permeability is measured by the permeability tester,but this approach has a high workload and limited application.In this paper,according to the reservoir characteristics of perforated horizontal wells,the reservoir is divided into two areas:the original reservoir area and the near-well high permeability reservoir area.Based on the theory of seepage mechanics and the formula of open hole productivity,the permeability calculation formula of near-well high permeability reservoir area with perforation parameters is deduced.According to the principle of seepage continuity,the seepage is regarded as the synthesis of two directions:the horizontal plane elliptic seepage field and the vertical plane radial seepage field,and the oil well productivity prediction model of the perforated horizontal well is established by partition.The model comparison demonstrates that the model is reasonable and feasible.To calculate and analyze the effect of oil well production and the law of influencing factors,actual production data of the oilfield are substituted into the oil well productivity formula.It can effectively guide the technical process design and effect prediction of perforated horizontal wells. 展开更多
关键词 perforated horizontal well PERMEABILITY productivity model sensitivity analysis
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Mediastinal emphysema in the context of perforated gastric ulcer
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作者 Debkumar Chowdhury 《World Journal of Clinical Cases》 SCIE 2024年第15期2479-2481,共3页
In the context of mediastinal emphysema/pneumomediastinum,the main aetiologies are associated with oesophageal perforation,lung pathology or post head and neck surgery related.The main way to differentiate the patholo... In the context of mediastinal emphysema/pneumomediastinum,the main aetiologies are associated with oesophageal perforation,lung pathology or post head and neck surgery related.The main way to differentiate the pathologies would be through Computed Tomographic Imaging of the Thorax and abdomen with oral and intravenous contrast in the context of triple phase imaging.The causes of pneumomediastinum should be differentiated between traumatic and non-traumatic.Oesophageal perforation(Boerhaave syndrome)is associated with Mackler’s triad in upto 50%of patients(severe retrosternal chest pain,pneumomediastinum,mediastinitis).Whereas in cases of lung pathology this can be associated with pneumothorax and pleural effusion. 展开更多
关键词 PNEUMOMEDIASTINUM Duodenal ulcer Computed tomography Visceral perforation Diagnostic imaging Emergency care
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Balloon dilation of congenital perforated duodenal web in newborns: Evaluation of short and long-term results
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作者 Kirill Marakhouski Elena Malyshka +5 位作者 Katsiaryna Nikalayeva Larysa Valiok Aleh Pataleta Kiryl Sanfirau Aliaksandr Svirsky Vasily Averin 《World Journal of Gastrointestinal Endoscopy》 2024年第6期343-349,共7页
BACKGROUND Incomplete congenital duodenal obstruction(ICDO)is caused by a congenitally perforated duodenal web(CPDW).Currently,only six cases of balloon dilatation of the PDW in newborns have been described.AIM To pre... BACKGROUND Incomplete congenital duodenal obstruction(ICDO)is caused by a congenitally perforated duodenal web(CPDW).Currently,only six cases of balloon dilatation of the PDW in newborns have been described.AIM To present our experience of balloon dilatation of a perforated duodenal memb-rane in newborns with ICDO.METHODS Five newborns who underwent balloon dilatation of the CPDW along a prein-stalled guidewire between 2021 and 2023 were included.Nineteen newborns diagnosed with ICDO who underwent laparotomy were included in the control group.RESULTS In all cases,good anatomical and clinical results were obtained.In three cases,a follow-up study was conducted after 1 year.The average time to start enteral feeding per os was significantly earlier in the study group(4.4 d)than in the laparotomic group(21.2 days;P<0.0001).The time spent by patients in the intensive care unit and hospital after balloon dilatation was also significantly shorter.We determined the selection criteria for possible and effective CPDW balloon dilatation in newborns as follows:(1)Presence of dynamic radiographic signs of the passage of a radiopaque substance beyond the zone of narrowing or radiographic signs of pneumatisation of the duodenum and small bowel distal to the web;(2)presence of endoscopic signs of CPDW;(3)successful cannulation with a guidewire performed parallel to the endoscope,with holes in the congenital duodenal web;and(4)successful positioning of the balloon performed along a freestanding guidewire on the web.CONCLUSION Strictly following selection criteria for newborns with ICDO caused by CPDW ensures that endoscopic balloon dilatation using a pre-installed guidewire is safe and effective and shows good 1-year follow-up results. 展开更多
关键词 NEWBORNS Congenital duodenal obstruction perforated duodenal membrane ENDOSCOPY Balloon dilation
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Correlation of serum albumin level on postoperative day 2 with hospital length of stay in patients undergoing emergency surgery for perforated peptic ulcer 被引量:1
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作者 Dan Xie Ping-Lan Lu +3 位作者 Wen Xu Jing-Ya You Xiao-Gang Bi Ying Xian 《World Journal of Gastrointestinal Surgery》 SCIE 2023年第7期1434-1441,共8页
BACKGROUND Perforated peptic ulcer(PPU)is a common emergency surgical condition and a significant cause of morbidity and mortality worldwide.While advances in surgical techniques have improved outcomes for patients wi... BACKGROUND Perforated peptic ulcer(PPU)is a common emergency surgical condition and a significant cause of morbidity and mortality worldwide.While advances in surgical techniques have improved outcomes for patients with PPU,many factors still affect postoperative hospital stay and overall prognosis.One potential factor is the serum albumin(SA)level,a widely utilized marker of nutritional status that has been associated with length of stay and complications in various surgical procedures.AIM To clarify the correlation of SA level on postoperative day 2 with hospital length of stay(HLOS)in patients undergoing emergency surgery for perforated peptic ulcer(PPU).METHODS We retrospectively collected and analyzed clinical baseline data,including blood routine and SA levels,of patients who underwent emergency PPU surgery and postoperative treatment at the Lingnan Hospital,the Third Affiliated Hospital of Sun Yat-sen University between December 2012 and September 2021.Patients were grouped according to HLOS with 7 d as the cut-off value,and relevant indicators were analyzed using SPSS 26.0.RESULTS Of the 37 patients undergoing emergency surgery for PPU referred to our department,33 had gastric and 4 had duodenal ulcer perforation.The median HLOS was 10 d.There were 8 patients in the≤7-d group(median HLOS:7 d)and 29 patients in the>7-d group(median HLOS:10 d).The≤7-d group had markedly higher SA on postoperative day 2 than the>7-d group(37.7 g/L vs 32.6g/L;P<0.05).The SA level on postoperative day 2 was a protective factor for patients with HLOS>7 d(Odds ratio=0.629,P=0.015).The cut-off of SA on postoperative day 2 was 30.6g/L,with an area under the curve of 0.86 and a negative predictive value of 100%for the prediction of HLOS≤7 d.CONCLUSION The SA level on postoperative day 2 was associated with the HLOS in patients undergoing emergency surgery for PPU.The pre-and post-operative albumin levels should be monitored,and infusion of human SA should be considered in a timely manner. 展开更多
关键词 perforated peptic ulcer Emergency surgery Serum albumin Hospital length of stay
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Late anastomotic perforation following surgery for gastric neuroendocrine tumor complicated by perforated duodenal ulcer:a case report 被引量:4
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作者 Jun Han Zhenyu He 《The Journal of Biomedical Research》 CAS 2013年第2期159-162,共4页
Neuroendocrine tumors (NETs) are a group of neoplasms that are characterized by the secretion of a variety of hormones and diverse clinical syndromes. NETs are considered to be rare, but the incidence of NETs has in... Neuroendocrine tumors (NETs) are a group of neoplasms that are characterized by the secretion of a variety of hormones and diverse clinical syndromes. NETs are considered to be rare, but the incidence of NETs has increased rapidly in recent years. NETs provide a clinical challenge for physicians because they comprise a heterogeneous group of malignancies with a wide range of morphological, functional, and behavioral characteristics. Subtotal gastrectomy with Billroth II reconstruction is the mainstay of therapy in the management of gastric NETs complicated by perforated duodenal ulcer. Late perforation of anastomotic stoma as a long-term complication has been rarely reported. Here, we report a case of anastomotic perforation 5 years after subtotal gastrectomy due to perforated duodenal ulcer and gastric NETs. 展开更多
关键词 anastomotic perforation neuroendocrine tumor COMPLICATIONS
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Numerical Study on Aerodynamic Performance of Floating Dual-Rotor Wind Turbines in Heave and Surge Motions
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作者 WU Xiao-di LU Wen-hao +3 位作者 WANG Kai HU Wei-fei FANG Jian-hao ZHA Ruo-si 《China Ocean Engineering》 SCIE EI CSCD 2023年第6期1011-1021,共11页
Compared with the traditional wind turbine of a single rotor,dual-rotor wind turbines(DRWTs)have higher wind energy capture efficiency and a more complex structure.Therefore,the aerodynamic performance of the DRWT ins... Compared with the traditional wind turbine of a single rotor,dual-rotor wind turbines(DRWTs)have higher wind energy capture efficiency and a more complex structure.Therefore,the aerodynamic performance of the DRWT installed on the floating platform will be greatly affected by the motion caused by wind and wave loads.In this paper,5 MW and 750 kW single rotor wind turbines(SRWTs)are combined into a 5 MW-5 MW DRWT and a 5 MW-750 kW DRWT,and their power output and wake field characteristics in different motions are studied.The flow field is obtained by solving the Reynolds-averaged Navier–Stokes equation(RANS).The overset grid technique is employed to achieve the large-amplitude multiple-degree-of-freedom motion of the DRWT.The overall performance of the 5 MW single rotor wind turbine is determined by a numerical method.For the DRWTs,numerical results show that the surge motion and heave motion both have a negative effect on the power output of the DRWT.The surge motion is a critical factor that causes the power output of the DRWT to periodically change with motion.The average power output of the DRWT influenced by motion is lower than that of a DRWT with a fixed bottom.The surge motion significantly disturbs the wake of the DRWT due to the mutual interference between the upstream and downstream rotors.Under the influence of heave motion,low-velocity regions downstream of the blade tip are enhanced.This study indicates that attenuating the surge and heave motion of offshore DRWT is very significant for improving its efficiency and should be taken into consideration during the design procedure. 展开更多
关键词 DRWT surge motion heave motion wake field power output
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Blast disruption using 3D grids/perforated plates for vehicle protection
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作者 Therese Schunck Dominique Eckenfels Laurent Sinniger 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2023年第7期60-68,共9页
In this work, blast disruption and mitigation using 3D grids/perforated plates were tested for underbelly and side protection of vehicles. Two vehicle simulants were used: a small-scale one for side vehicle protection... In this work, blast disruption and mitigation using 3D grids/perforated plates were tested for underbelly and side protection of vehicles. Two vehicle simulants were used: a small-scale one for side vehicle protection assessment and a true-to-scale simulant for underbelly protection testing. The deformation of target plates was assessed. These were either unprotected or protected by three different types of disruptors. The first disruptor was made of a sandwich structure of two perforated plates filled with a thin aluminum structure allowing the air to pass through. The two other disruptors were made of pieces of cast metallic foam. Two different kinds of foams were used: one with large cells and the second one with small cells. Beforehand, the mitigation efficiency of the disruptors was evaluated using an explosivedriven shock tube(EDST). The experiments showed that blast disruption/mitigation by 3D grid/perforated plate structures was not suitable for vehicle side protection. However, 3D grids/perforated structures proved to be relatively effective for underbelly protection compared to an equivalent mass of steel. 展开更多
关键词 BLAST MITIGATION perforated plates 3D grids Vehicle protection
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A black perforated esophagus treated with surgery:Report of a case 被引量:1
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作者 Roosmarijn Lysbeth Groenveld Alderina Bijlsma +1 位作者 Pascal Steenvoorde Alaattin Ozdemir 《World Journal of Gastrointestinal Surgery》 SCIE CAS 2013年第6期199-201,共3页
A case of a perforated black esophagus treated with minimal invasive surgery is presented.A 68-year-old women underwent a right-sided hemihepatectomy and radio frequency ablation of two metastasis in the left liver lo... A case of a perforated black esophagus treated with minimal invasive surgery is presented.A 68-year-old women underwent a right-sided hemihepatectomy and radio frequency ablation of two metastasis in the left liver lobe.Previous history revealed a hemicolectomy for an obstructive colon carcinoma with post-operative chemotherapy.Postoperatively she developed severe dyspnea due to a perforation of the esophagus with leakage to the pleural space.Video-assisted thoracoscopic surgery(VATS) to adequately drain the perforation was performed.Gastroscopy revealed a perforated black esophagus.The black esophagus,acute esophageal necrosis or Gurvits syndrome is a rare entity with an unknown aetiology which is likely to be multifactorial.The estimated mortality rate is high.To our knowledge,this is the first case published of early VATS used in a case of perforated black esophagus. 展开更多
关键词 BLACK ESOPHAGUS Acute esophageal NECROSIS Video assisted THORACOSCOPIC surgERY GASTROINTESTINAL surgERY perforated ESOPHAGUS
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Numerical Analysis of Residual Strength in the Perforated Casing of Ultra Deep Wells
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作者 Yanxian Wu Shouming Zhong +7 位作者 Zhigang Guan Lin Song Kun Li Jiarui Sun Yuqiang Xu Maochuan Tu Chaobin Fan Jinbin Yang 《Fluid Dynamics & Materials Processing》 EI 2023年第1期261-271,共11页
A three-dimensional model for the numerical simulation of casing-cement behavior is used to investigate residual strength in the perforated casing of ultra deep wells.The influence of the hole diameter,hole density an... A three-dimensional model for the numerical simulation of casing-cement behavior is used to investigate residual strength in the perforated casing of ultra deep wells.The influence of the hole diameter,hole density and phase angle on the residual strength of the casing under non-uniform stress and fracturing conditions is revealed through the consideration of different perforation parameters.It is shown that the residual strength of the casing increases with the hole diameter and periodically changes with the hole density;the phase angle is the main factor that affects the residual strength of the perforated casing,and the perforation should be avoided in the direction of the minimum principal stress to reduce stress concentration at the perforation hole.Moreover,as shown by a companion orthogonal experiment,the descending order of influence of the different influential parameters is:phase angle,hole diameter,hole density and the thickness of casing. 展开更多
关键词 perforated casing non-uniform stress residual strength orthogonal experiment
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Calculation and Analysis of Acoustic Characteristics of Straight-Through Perforated Pipe Muffler Based on Multilayer Sound Absorbing Material
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作者 刘镕基 朱从云 +1 位作者 丁国芳 院蕾 《Journal of Donghua University(English Edition)》 CAS 2023年第5期506-514,共9页
Using the multi-physical field simulation software COMSOL,the acoustic characteristics of the multilayer sound absorbing material straight-through perforated pipe muffler are studied by the finite element method.The r... Using the multi-physical field simulation software COMSOL,the acoustic characteristics of the multilayer sound absorbing material straight-through perforated pipe muffler are studied by the finite element method.The results show that the finite element calculation of the multilayer sound absorbing material straight-through the perforated pipe muffler agrees well with the experimental measurement results.The reliability of the finite element method for studying the acoustic performance of the straight-through perforated pipe muffler with multilayer sound absorbing materials is shown.Furthermore,the influence of some structural parameters of porous sound absorbing material and micro-perforated plate on the acoustic performance of the multilayer sound absorbing material straight-through perforated pipe muffler is analyzed.The muffler based on multilayer sound absorbing material is different from the traditional muffler.After applying the multilayer sound absorbing material to the straight-through perforated pipe muffler,the transmission loss value greatly increases,which provides new ideas and directions for future research on the muffler. 展开更多
关键词 porous sound absorbing material perforated tube finite element method MUFFLER acoustic characteristics
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Surgical Outcomes Following Partial Breast Reconstruction with Chest Wall Perforator Flaps
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作者 Manas Kumar Dube Rishabha Deva Sharma Devanand Puthu 《Surgical Science》 2023年第4期277-288,共12页
Introduction: In the last two decades, chest wall perforator flaps (CWPF) have become a versatile tissue replacement technique for partial breast reconstruction following breast-conserving surgery (BCS) in well-select... Introduction: In the last two decades, chest wall perforator flaps (CWPF) have become a versatile tissue replacement technique for partial breast reconstruction following breast-conserving surgery (BCS) in well-selected cases. We present the surgical outcome of 81 patients with chest wall perforator flaps used for breast-conserving surgery. Methods: We recorded the outcomes of three oncoplastic breast surgeons who performed partial breast reconstruction with chest wall perforator flaps from 1<sup>st</sup> January 2018 to 30<sup>th</sup> June 2022 at Sherwood Forest Hospitals NHS Foundation Trust. Data were collected on patient demographics, including age, BMI, smoking status, bra size, previous treatments, type of CWPF procedure, tumor size (measured clinically, via imaging and histologically), biopsy results, specimen weight, margins involvement, re-operation rate, surgical site infection (SSI), flap loss, flap shrinkage, hematoma, and seroma rates. Results: A total of 81 patients were included in this study, with an average age of 55.7 years and a body mass index (BMI) of 26.7 kg/m<sup>2</sup>. The bra size varied between A to FF with A (7.4%), B (28.3%), C (38.2%), D (13.6%), DD (11.1%), and FF (1.2%). 14.8% of the patients had neoadjuvant chemotherapy (NACT). For 45 patients, LICAP (lateral intercostal artery perforator), 16 AICAP (anterior intercostal artery perforator), 13 MICAP (medial intercostal artery perforator), and for seven patients, LTAP (lateral thoracic artery perforator) flaps were used. The average tumor was measured at 15.75 mm clinically, 19.1 mm via imaging, and 19.6 mm histologically. Biopsy showed that 16% of the tumors were ductal carcinoma in situ (DCIS), and 84% were invasive. 16% of patients had involved margins, and re-excision was required in 10 patients, and completion mastectomy was performed in 2 patients. A thirty-day SSI rate was 6.2%, with flap-related complications, including flap loss and shrinkage, at 3.7% and 4.9%, respectively. In addition, 3.7% had a hematoma, and 17.3% had other complications. Conclusion: Partial breast reconstruction with perforator flaps is an excellent volume replacement technique in breast-conserving surgery with acceptable complications in well-selected cases. 展开更多
关键词 Breast-Conserving surgery Chest Wall perforator Flap Breast Reconstruction surgery Partial Breast Reconstruction Breast Tissue Replacement
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Devastating complication of negative pressure wound therapy after deep inferior epigastric perforator free flap surgery:A case report
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作者 SooA Lim Dong Yun Lee +3 位作者 BumSik Kim Jung Soo Yoon Yea Sik Han SuRak Eo 《World Journal of Clinical Cases》 SCIE 2023年第1期143-149,共7页
BACKGROUND Thermal injuries on free transferred or replanted tissues resulting from loss of sensibility are an infrequent occurrence.They require immediate and appropriate management before they progress to an irrever... BACKGROUND Thermal injuries on free transferred or replanted tissues resulting from loss of sensibility are an infrequent occurrence.They require immediate and appropriate management before they progress to an irreversible condition.Although negative pressure wound therapy(NPWT)can prevent wound progression by increasing microcirculation,the inappropriate application of NPWT on complicationthreatened transferred and replanted tissues can induce an adverse effect.CASE SUMMARY A 48-year-old woman who underwent immediate breast reconstruction with a deep inferior epigastric artery perforator free flap.While applying a heating pad directly to the flap site,she sustained a deep second to third-degree contact burn over 30%of the transferred flap on postoperative 7 d.As the necrotic changes had progressed,we applied an NPWT dressing over the burned area after en-bloc debridement of the transferred tissues on postoperative 21 d.After 4 d of NPWT application,the exposed fatty tissues of the flap changed to dry and browncolored necrotic tissues.Upon further debridement,we noted that the wound gradually reached total necrosis with a collapsed vascular pedicle of deep inferior epigastric artery.CONCLUSION Although NPWT has been shown to be successful for treating various wound types,the significant risk of NPWT application in short-lasting reconstructed flap wounds after thermal injury should be reminded. 展开更多
关键词 Negative Pressure Wound Therapy COMPLICATIONS Breast reconstruction Deep inferior epigastric artery perforator Free flap Burn injury Case report
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Numerical Analysis of Perforation during Hydraulic Fracture Initiation Based on Continuous-Discontinuous Element Method
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作者 Rui Zhang LixiangW ang +2 位作者 Jing Li Chun Feng Yiming Zhang 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第8期2103-2129,共27页
Perforation is a pivotal technique employed to establish main flow channels within the reservoir formation at the outset of hydraulic fracturing operations.Optimizing perforation designs is critical for augmenting the... Perforation is a pivotal technique employed to establish main flow channels within the reservoir formation at the outset of hydraulic fracturing operations.Optimizing perforation designs is critical for augmenting the efficacy of hydraulic fracturing and boosting oil or gas production.In this study,we employ a hybrid finite-discrete element method,known as the continuous–discontinuous element method(CDEM),to simulate the initiation of post-perforation hydraulic fractures and to derive enhanced design parameters.The model incorporates the four most prevalent perforation geometries,as delineated in an engineering technical report.Real-world perforations deviate from the ideal cylindrical shape,exhibiting variable cross-sectional profiles that typically manifest as an initial constriction followed by an expansion,a feature consistent across all four perforation types.Our simulations take into account variations in perforation hole geometries,cross-sectional diameters,and perforation lengths.The findings show that perforations generated by the 39g DP3 HMX perforating bullet yield the lowest breakdown pressure,which inversely correlates with increases in sectional diameter and perforation length.Moreover,this study reveals the relationship between breakdown pressure and fracture degree,providing valuable insights for engineers and designers to refine perforation strategies. 展开更多
关键词 Hydraulic fracturing real perforation shape breakdown pressure perforation layout design CDEM
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Conquer coronary artery perforation with magic hands
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作者 Yi-Lun ZOU Jian-Qiang LI +3 位作者 Ding-Yu WANG Yong-Tai GONG Li SHENG Yue LI 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2024年第4期379-386,共8页
Coronary artery perforation(CAP) poses a significant challenge for interventional cardiologists. Management of CAP depends on the location and severity of the perforation. The conventional method for addressing the pe... Coronary artery perforation(CAP) poses a significant challenge for interventional cardiologists. Management of CAP depends on the location and severity of the perforation. The conventional method for addressing the perforation of large vessels involves the placement of a covered stent, while the perforation of distal and collateral vessels is typically managed using coils, autologous skin, subcutaneous fat, microspheres, gelatin sponge, thrombin or other substances. However, the above techniques have certain limitations and are not applicable in all scenarios. Our team has developed a range of innovative strategies for effectively managing CAP. This article provides an insightful review of the various tips and tricks for the treatment of CAP. 展开更多
关键词 CORONARY SPONGE perforATION
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Pedicled abdominal flap using deep inferior epigastric artery perforators for forearm reconstruction: A case report
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作者 Jae Hyung Jeon Kyung Wook Kim Hong Bae Jeon 《World Journal of Clinical Cases》 SCIE 2024年第4期828-834,共7页
BACKGROUND Pedicled abdominal flaps are a widely used surgical technique for forearm reconstruction in patients with soft tissue defects.However,some drawbacks include restricted flap size,partial flap loss,and donor-... BACKGROUND Pedicled abdominal flaps are a widely used surgical technique for forearm reconstruction in patients with soft tissue defects.However,some drawbacks include restricted flap size,partial flap loss,and donor-site morbidity.To address these concerns,we present a case of a pedicled abdominal flap using the deep inferior epigastric artery perforators(DIEP)for forearm reconstruction in a patient with a large soft tissue defect.CASE SUMMARY A 46-year-old male patient was admitted to our hospital with forearm injury caused by a pressing machine.A 15 cm×10 cm soft tissue defect with complete rupture of the ulnar side structures of the forearm was found.One week after orthopedic management of the neurovascular injury and fractures using the first stage of Masquelet technique,the patient was referred to the plastic and recon-structive surgery department for wound coverage.Surgical debridement and negative-pressure wound therapy revealed a 20 cm×15 cm soft tissue defect.A pedicle abdominal flap with the DIEP was used to cover the defect.Three weeks later,the flap was detached from the abdomen,and the abdominal defect was directly closed.Subsequently,the second stage of Masquelet technique was performed at the fracture site at week 10.Finally,all donor and recipient sites healed without complications,such as flap dehiscence,infection,hematoma,or necrosis.Fracture site osteosynthesis was achieved without complications.CONCLUSION Pedicled abdominal flap using the DIEP provides a reliable option for forearm reconstruction in patients with large soft tissue defects. 展开更多
关键词 Forearm injury Open fracture reduction perforator flap Deep inferior epigastric artery perforators Case report
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Simple procedure for assessing diffuse subarachnoid hemorrhage successfully created using filament perforation method in mice
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作者 Tatsushi Mutoh Ryota Tochinai +3 位作者 Hiroaki Aono Masayoshi Kuwahara Yasuyuki Taki Tatsuya Ishikawa 《Animal Models and Experimental Medicine》 CAS CSCD 2024年第1期77-81,共5页
The murine model of subarachnoid hemorrhage(SAH)is a valuable experimental tool for investigating molecular and cellular mechanisms,and the endovascular filament perforation technique can be used to simulate prominent... The murine model of subarachnoid hemorrhage(SAH)is a valuable experimental tool for investigating molecular and cellular mechanisms,and the endovascular filament perforation technique can be used to simulate prominent pathophysiological features observed after human SAH;however,current validation methods for assessing an appropriate SAH model are limited.Here,we introduce a simple procedure for se-lecting a mouse model of diffuse SAH.SAH was induced in 24 mice using a standard filament perforation method.After confirming survival at 24 h,SAH was scored 0-1 based on T2*-weighted images on whole-brain magnetic resonance imaging(MRI)and visual surveillance of the cisterna magna(CM)through the dura mater.The CM-based SAH grading correlated well with a reference parameter defined by extracted brain(r^(2)=0.53,p<0.0001).The receiver operating characteristic curve revealed a sensi-tivity of 85%and a specificity of 91%for detecting diffuse SAH,with a similar area under the curve(0.89±0.06[standard error of the mean])as the MRI-based grading(0.72±0.10,p=0.12).Our data suggest that confirming an SAH clot in the CM is a valuable way to select a clinically relevant diffuse SAH model that can be used in future experimental studies. 展开更多
关键词 cisterna magna clot distribution filament perforation mouse model subarachnoid hemorrhage
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Trend of Storm Surge Induced by Typical Landfall Super Typhoons During 1975–2021 in the Eastern China Sea
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作者 LUO Feng WANG Yi +3 位作者 TAO Aifeng SHI Jian WANG Yongzhi ZHANG Chi 《Journal of Ocean University of China》 CAS CSCD 2024年第2期277-286,共10页
Climate change affects the activity of global and regional tropical cyclones(TCs).Among all TCs,typical super typhoons(STYs)are particularly devastating because they maintain their intensity when landing on the coast ... Climate change affects the activity of global and regional tropical cyclones(TCs).Among all TCs,typical super typhoons(STYs)are particularly devastating because they maintain their intensity when landing on the coast and thus cause casualties,economic losses,and environmental damage.Using a 3D tidal model,we reconstructed the typhoon(TY)wind field to simulate the storm surge induced by typical STYs.The TY activity was then analyzed using historical data.Results showed a downtrend of varying degrees in the annual frequency of STYs and TCs in the Western North Pacific(WNP)Basin,with a significant trend change observed for TCs from 1949 to 2021.A large difference in the interannual change in frequency was found between STYs and TCs in the WNP and Eastern China Sea(ECS).Along the coast of EC,the frequency of landfall TCs showed a weak downtrend,and the typical STYs showed reverse micro growth with peak activity in August.Zhejiang,Fujian,and Taiwan were highly vulnerable to the frontal hits of typical STYs.Affected by climate change,the average lifetime maximum intensity(LMI)locations and landfall locations of typical STYs in the ECS basin showed a significant poleward migration trend.In addition,the annual average LMI and accumulated cyclone energy showed an uptrend,indicating the increasing severity of the disaster risk.Affected by the typical STY activity in the ECS,the maximum storm surge area also showed poleward migration,and the coast of North China faced potential growth in high storm surge risks. 展开更多
关键词 storm surge super typhoons tropical cyclones eastern China Sea poleward migration
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