Positron emission tomography(PET)is a powerful non-invasive molecular imaging technique for the early detection,characterization,and"real-time"monitoring of disease,and for investigating the efficacy of drug...Positron emission tomography(PET)is a powerful non-invasive molecular imaging technique for the early detection,characterization,and"real-time"monitoring of disease,and for investigating the efficacy of drugs(Phelps,2000;Ametamey et al.,2008).The development of molecular probes bearing shortlived positron-emitting radionuclides,such as 18F(half-life 110 min)or HC(half-life 20 min),is crucial for PET imaging to collect in vivo metabolic information in a time-efficient manner(Deng et al.,2019).展开更多
基金supported by the National Natural Science Foundation of China(Nos.81425015 and 81327004)the Ministry of Science and Technology of China(No.2016YFA0100900)
文摘Positron emission tomography(PET)is a powerful non-invasive molecular imaging technique for the early detection,characterization,and"real-time"monitoring of disease,and for investigating the efficacy of drugs(Phelps,2000;Ametamey et al.,2008).The development of molecular probes bearing shortlived positron-emitting radionuclides,such as 18F(half-life 110 min)or HC(half-life 20 min),is crucial for PET imaging to collect in vivo metabolic information in a time-efficient manner(Deng et al.,2019).
