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Experimental and numerical study on the influence of shaped charge liner cavity filing on jet penetration characteristics in steel targets
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作者 Paweł Zochowski Radosław Warchoł 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2023年第5期60-74,共15页
Penetration characteristic(size and shape of penetration craters made in high hardness ARMSTAL 30PM steel) of shaped charge jets formed after detonations of modified PG-7VM warheads was analyzed in the article. Modifi... Penetration characteristic(size and shape of penetration craters made in high hardness ARMSTAL 30PM steel) of shaped charge jets formed after detonations of modified PG-7VM warheads was analyzed in the article. Modifications consisted in removing the frontal part of the grenade(fuse, ballistic cap and conductive cone) and introducing of the liner cavity filling made of polyacetal copolymer POM-C. The filings in the form of solid cones with three different heights(33%, 66% and 100% of H-the height of original PG-7VM liner) were placed inside of the hollow cone shaped charge liner. As opposed to the vast majority of previously published works(in which warhead optimization studies were focused on increasing of the depth of penetration in rolled homogeneous armor steel) the main aim of the presented modifications was to maximize the damage ratio(diameters of craters, inlet and outlet holes) of target perforated by shaped charge jet at the cost of the loss of part of the jet penetration capability. According to the best knowledge of the authors such approach to the use of the old PG-7VM warheads has not been analyzed so far. Taking into consideration high stock levels of PG-7VM warheads, and the fact that they are continuously being replaced by more efficient and more sophisticated high-explosive anti-tank warheads, it seems reasonable to look for alternate applications of the warheads withdrawn from the service. Thanks to the introduction of proposed modifications the warheads could be used by special forces or other assault units as directional mines or statically detonated cutting shaped charges as well as by combat engineers as universal charges used in various types of engineering or sapper works. The research included experimental penetration tests and their numerical reproduction in the LS-Dyna software with the simulation methodology defined and validated in previous works of the authors.Small differences(average error = 10-20%) were identified between the experimental and numerical results(dimensions of craters made in steel targets were compared) what confirmed the reliability of the modelling methodology and enabled its use for further optimization of the shapes of fillings. Within the analyzed variants of warheads modifications maximum diameters of penetration craters were obtained for the filling of the height of h = 2/3H. The diameters of holes in individual steel plates were increased by 164%, 70%, 65%(for the first, second and third plate, respectively) in relation to the variant without filling. The results of the study indicated that with the use of different materials of fillings and their various heights it is possible to control the shape of penetration craters pierced in the steel targets. 展开更多
关键词 Shaped charge jet pg-7 grenade Armor steel target Finite element modeling Penetration process
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蛋白酶抑制剂leupeptin增强抗肿瘤药物对肿瘤细胞的增殖抑制作用 被引量:2
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作者 王莹 吴淑英 甄永苏 《医学研究杂志》 2012年第10期56-60,共5页
目的研究蛋白酶抑制剂(protease inhibitor)leupeptin对化疗药物紫杉醇(taxol,TAX)、吉西他滨(gemcitabine,GEM)以及平阳霉素(pingyangmycin,PYM)在体外抑制肿瘤细胞增殖作用的影响。方法选取一定浓度梯度的酶抑制剂leupep-tin单独或联... 目的研究蛋白酶抑制剂(protease inhibitor)leupeptin对化疗药物紫杉醇(taxol,TAX)、吉西他滨(gemcitabine,GEM)以及平阳霉素(pingyangmycin,PYM)在体外抑制肿瘤细胞增殖作用的影响。方法选取一定浓度梯度的酶抑制剂leupep-tin单独或联合TAX、GEM和PYM与肿瘤细胞孵育,48h后采用MTT法测定肿瘤细胞生长的变化并与相应浓度的TAX、GEM和PYM单药组相比较。采用流式细胞术测定MCF-7细胞周期分布。结果 leupeptin在浓度高于50μmol/L时可增强化疗药物对肺癌PG细胞和乳腺癌MCF-7细胞增殖的抑制作用。leupeptin对TAX的增效作用尤为显著。leupeptin与低浓度的GEM和TAX联合应用可改变MCF-7的细胞周期分布。结论 leupeptin可增强化疗药物对肿瘤细胞增殖的抑制作用,但其作用程度与肿瘤细胞株的种类、化疗药物的种类及leupeptin的浓度均相关。 展开更多
关键词 LEUPEPTIN MCF-7细胞 PG细胞 增殖抑制
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胚胎植入前遗传学诊断及筛查中7-细胞来源与9-细胞来源囊胚胚胎正常率和临床妊娠率的比较 被引量:2
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作者 李昀 仲万霞 +2 位作者 姚宁 胡双纲 刘洪卯 《中华生殖与避孕杂志》 CAS CSCD 北大核心 2018年第4期270-273,共4页
目的研究在胚胎植入前遗传学诊断及筛查(PGD/PGS)中7-细胞来源与9-细胞来源囊胚的胚胎正常率和临床妊娠率,探讨胚胎体外培养第3日时的最适分裂速度。方法回顾性分析2014年4月1日—2015年12月31日期间207例PGD/PGS治疗周期的临床资料。比... 目的研究在胚胎植入前遗传学诊断及筛查(PGD/PGS)中7-细胞来源与9-细胞来源囊胚的胚胎正常率和临床妊娠率,探讨胚胎体外培养第3日时的最适分裂速度。方法回顾性分析2014年4月1日—2015年12月31日期间207例PGD/PGS治疗周期的临床资料。比较7-细胞来源与9-细胞来源囊胚的胚胎正常率和临床妊娠率。结果 7-细胞来源与9-细胞来源囊胚的胚胎正常率分别为34.38%和52.63%,两者比较差异有统计学意义(c2=4.100,P=0.042 9)。7-细胞来源与9-细胞来源囊胚的临床妊娠率分别为55.56%和57.14%,两者比较差异无统计学意义(c2=0.004,P>0.05)。结论在PGD/PGS中,9-细胞来源囊胚的胚胎正常率比7-细胞来源囊胚高,移植的两类胚胎能够获得类似的临床妊娠率。在体外培养第3日选择胚胎移植时,如果胚胎的分级相同,那么9-细胞胚胎优于7-细胞胚胎。 展开更多
关键词 植入前遗传学诊断及筛查(PGD/PGS) 7-细胞来源囊胚 9-细胞来源囊胚 囊胚活检 正常率 临床妊娠率
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俄罗斯最新研制的温压榴弹
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作者 方芳 《轻武器论证研究》 2002年第5期30-32,共3页
关键词 俄罗斯 温压榴弹 RShG-1 pg-7VR Rpg-29
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