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医用纤维材料PGLA910的直接熔融聚合法研究 被引量:2
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作者 汪朝阳 赵耀明 +2 位作者 王方 许娟 曹曼丽 《合成纤维》 CAS 北大核心 2004年第4期12-14,共3页
分别以D,L-乳酸(D,L-LA)、L-乳酸(L-LA)为原料,与乙醇酸(GA)通过熔融聚合法进行共聚,在催化剂SnCl2用量0.5%(wt)、反应温度165℃、反应压力70Pa、反应时间10h的条件下直接合成了生物降解的医用纤维材料聚乙醇酸-乳酸(90/10)(PGLA 910)... 分别以D,L-乳酸(D,L-LA)、L-乳酸(L-LA)为原料,与乙醇酸(GA)通过熔融聚合法进行共聚,在催化剂SnCl2用量0.5%(wt)、反应温度165℃、反应压力70Pa、反应时间10h的条件下直接合成了生物降解的医用纤维材料聚乙醇酸-乳酸(90/10)(PGLA 910)。产品用IR、DSC、X-射线衍射等进行了表征,并与乙交酯开环聚合二步法合成的PGLA910进行了比较。直接熔融聚合产品的结晶度接近于二步法,D,L-PGLA910的结晶度和微晶尺寸比L型的大。直接熔融共聚工艺流程短、简单易行、耗时少、成本低,有利于医用纤维材料PGLA910的规模开发。 展开更多
关键词 医用纤维 D L-乳酸 L-乳酸 乙醇酸 直接熔融聚合法 聚己醇酸-乳酸 氯化锡 生物降解材料
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会阴修补中应用铬制肠线、聚乳酸羟基乙酸(PGLA)910缝线、快速吸收PGLA910缝线的效果比较:一项随机对照试验 被引量:1
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作者 Leroux N. Bujold E. 翁梨驹 《世界核心医学期刊文摘(妇产科学分册)》 2006年第12期4-4,共1页
Objective: The goal of our study was to compare the impact of 3 suture materials on perineal pain and on resumption of sexual intercourse. Study design: This randomized, controlled trial compared 3 types of suture mat... Objective: The goal of our study was to compare the impact of 3 suture materials on perineal pain and on resumption of sexual intercourse. Study design: This randomized, controlled trial compared 3 types of suture materials (chromic catgut, polyglactin 0910, fast-absorbing polyglactin 910) for second-degree perineal laceration or uncomplicated episiotomy. Patients were enrolled in early labor and assigned randomly to 1 of the 3 suture materials. Pain was evaluated at 48 hours, 6 weeks, and 3 months. The study subjects were questioned about residual perineal pain, resumption of sexual activity, and pain-free sexual intercourse. Logistic regression analyses were undertaken. Results: Of the 192 patients who were assigned randomly to groups, 66 patients had their perineal laceration repaired with chromic catgut; 60 patients had repair with polyglactin 910, and 66 patients had repair with fast-absorbing polyglactin 910. At 48 hours, there was no significant difference according to the pain measurement scores, but the median consumption of analgesics was significantly lower with fast-absorbing polyglactin 910 than with standard polyglactin 910. There was no difference in the resumption of sexual intercourse at 6 weeks after the delivery between chromic catgut (42%) compared with standard polyglactin 910 group (56%; P = .23). However, it was more frequent for women in the fast-absorbing polyglactin 910 group (66%; P = .02). After adjustment for confounding variables, perineal repair with fast-absorbing polyglactin 910 was associated with a higher rate of sexual intercourse (odds ratio, 2.55; 95%CI, 1.07-6.10) and a higher rate of pain-free sexual intercourse (odds ratio, 2.51; 95%CI, 1.03-6.10) at 6 weeks after delivery. Conclusion: Fast-absorbing polyglactin 910 for perineal repair is associated with earlier resumption of sexual intercourse when compared with chromic catgut. 展开更多
关键词 铬制肠线 聚乳酸羟基乙酸 PGLA)910 pgla910 随机对照试验 缝线材料 疼痛感 疼痛评估
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