探究了个体微环境中P M 2.5的水平与皮肤状态间的关系,包括对皮肤水分和油脂含量的影响,从而为个性化、精确化的皮肤护理方案提供思路和参考。通过便携式空气质量监测设备和皮肤检测设备实时监控40名女性受试者的空气质量和皮肤状态,使...探究了个体微环境中P M 2.5的水平与皮肤状态间的关系,包括对皮肤水分和油脂含量的影响,从而为个性化、精确化的皮肤护理方案提供思路和参考。通过便携式空气质量监测设备和皮肤检测设备实时监控40名女性受试者的空气质量和皮肤状态,使用无线网络传输实时数据。结果显示,个体微环境中P M 2.5的水平对皮肤水分无显著影响,但对皮脂含量影响显著,说明P M 2.5能够通过影响皮脂含量从而影响皮肤状态,进而导致皮肤可能的水油失衡,引发多种皮肤问题。展开更多
The health effects of ambient PM 2.5 and its potential mechanisms have generated considerable interest.In vitro cell studies and ex vivo animal experiments may not accurately determine the characteristics of PM 2.5 pa...The health effects of ambient PM 2.5 and its potential mechanisms have generated considerable interest.In vitro cell studies and ex vivo animal experiments may not accurately determine the characteristics of PM 2.5 particles.To better understand their detailed mechanisms,we performed an in vivo study using single photon emission tomography(SPECT)imaging.To mimic the PM 2.5 particles,SiO2 nanoparticles modified by ethylene carbonate or polyvinyl pyrrolidone were labeled with 131I.After administration via inhalation,in vivo SPECT imaging of the radiolabeled particles in sprague dawley rats was performed.It was found that radioactivity accumulated in the lungs and trachea 6 and 24 h after administration.In addition,significant radioactivity was observed in the abdomen,including the liver and kidneys.The results were also confirmed by ex vivo autoradiography.This study revealed that in vivo SPECT imaging could be an effective method for investigating the properties of PM 2.5 particles.展开更多
Based on the real-time data released by 17 atmospheric automatic stations in Chongqing,the pollution characteristics and variation trends of PM 2.5 and PM 10 and their correlations with meteorological factors from Jan...Based on the real-time data released by 17 atmospheric automatic stations in Chongqing,the pollution characteristics and variation trends of PM 2.5 and PM 10 and their correlations with meteorological factors from January 2014 to December 2018 were analyzed.The results show that the annual average mass concentration of PM 2.5 in Chongqing reduced from 65μg/m 3 in 2014 to 40μg/m 3 in 2018,and the annual average mass concentration of PM 10 decreased from 98μg/m 3 in 2014 to 64μg/m 3 in 2018.However,the annual average mass concentration of PM 2.5 in Chongqing from 2014 to 2018 and the annual average mass concentration of PM 10 from 2014 to 2016 exceeded the national level II standard,and the maximum exceeding standard rate was up to 0.86 and 0.40 times respectively.The monthly average mass concentration of PM 2.5 and PM 10 changed obviously,and the overall distribution was"U"-shaped.The ratio of PM 2.5 to PM 10 mass concentration ranged from 47.4%to 80.7%,with an average of 62.4%.The Pearson correlation coefficient between the mass concentration of PM 2.5 and PM 10 varied from 0.961 to 0.989,and there was a significant correlation at the confidence level of 0.01(bilateral).The mass concentration of PM 2.5 and PM 10 was extremely significantly correlated with average temperature,precipitation,and average air pressure,while there was no significant correlation between the mass concentrations of PM 2.5 and PM 10 and average relative humidity.The mass concentration of PM 2.5 and PM 10 was significantly correlated with sunshine duration.展开更多
文摘探究了个体微环境中P M 2.5的水平与皮肤状态间的关系,包括对皮肤水分和油脂含量的影响,从而为个性化、精确化的皮肤护理方案提供思路和参考。通过便携式空气质量监测设备和皮肤检测设备实时监控40名女性受试者的空气质量和皮肤状态,使用无线网络传输实时数据。结果显示,个体微环境中P M 2.5的水平对皮肤水分无显著影响,但对皮脂含量影响显著,说明P M 2.5能够通过影响皮脂含量从而影响皮肤状态,进而导致皮肤可能的水油失衡,引发多种皮肤问题。
基金supported by the National Natural Science Foundation of China(Nos.31671035,51803082)National Significant New Drugs Creation Program(No.2017ZX09304021)+1 种基金Jiangsu Province Foundation(Nos.BK20170204,BK20161137)Jiangsu Provincial Medical Innovation Team(Nos.CXTDA2017024,LGY2017088,QNRC2016628)。
文摘The health effects of ambient PM 2.5 and its potential mechanisms have generated considerable interest.In vitro cell studies and ex vivo animal experiments may not accurately determine the characteristics of PM 2.5 particles.To better understand their detailed mechanisms,we performed an in vivo study using single photon emission tomography(SPECT)imaging.To mimic the PM 2.5 particles,SiO2 nanoparticles modified by ethylene carbonate or polyvinyl pyrrolidone were labeled with 131I.After administration via inhalation,in vivo SPECT imaging of the radiolabeled particles in sprague dawley rats was performed.It was found that radioactivity accumulated in the lungs and trachea 6 and 24 h after administration.In addition,significant radioactivity was observed in the abdomen,including the liver and kidneys.The results were also confirmed by ex vivo autoradiography.This study revealed that in vivo SPECT imaging could be an effective method for investigating the properties of PM 2.5 particles.
文摘Based on the real-time data released by 17 atmospheric automatic stations in Chongqing,the pollution characteristics and variation trends of PM 2.5 and PM 10 and their correlations with meteorological factors from January 2014 to December 2018 were analyzed.The results show that the annual average mass concentration of PM 2.5 in Chongqing reduced from 65μg/m 3 in 2014 to 40μg/m 3 in 2018,and the annual average mass concentration of PM 10 decreased from 98μg/m 3 in 2014 to 64μg/m 3 in 2018.However,the annual average mass concentration of PM 2.5 in Chongqing from 2014 to 2018 and the annual average mass concentration of PM 10 from 2014 to 2016 exceeded the national level II standard,and the maximum exceeding standard rate was up to 0.86 and 0.40 times respectively.The monthly average mass concentration of PM 2.5 and PM 10 changed obviously,and the overall distribution was"U"-shaped.The ratio of PM 2.5 to PM 10 mass concentration ranged from 47.4%to 80.7%,with an average of 62.4%.The Pearson correlation coefficient between the mass concentration of PM 2.5 and PM 10 varied from 0.961 to 0.989,and there was a significant correlation at the confidence level of 0.01(bilateral).The mass concentration of PM 2.5 and PM 10 was extremely significantly correlated with average temperature,precipitation,and average air pressure,while there was no significant correlation between the mass concentrations of PM 2.5 and PM 10 and average relative humidity.The mass concentration of PM 2.5 and PM 10 was significantly correlated with sunshine duration.
