TREATMENT OF ACUTE DISEASES OF PHARYNX AND LARYNX WITH BLOOD-PRICKING THERAPY

This article deals with a treatment of acute diseases of pharynx and larynx with bloodpricking therapy, in this treatment, a group of 79 patients accepted the treatment with this therapy.The therapy contains mainly two methods: Acupoint pricking and local scattered pricking. A good result is achieved. It proves that blood-pricking method can replace the antibiotics and alleviate the sufferer’s pain and economic burden. It is simple and easy to carry out, thus it can be spread extensively.

CLINICAL OBSERVATION ON THE THERAPEUTIC EFFECT OF PRICKING BLOOD OF SHAOSHANG AND SHANGYANG FOR TREATMENT OF 100 CASES OF ACUTE TONSILLITIS

In this series of treatment, 100 cases of acute tonsillitis were treated using pricking blood therapy. After 1 session of treatment, 36 cases were cured; after 2 sessions, 44 cured and after 3 sessions, 18 cured, with the cure rate being 98%. This therapy works very well in treating acute tonsillitis.

OBSERVATION OF 14 CASES OF LARYNGEAL CARBUNCLE TREATED BY WEI JIA'S BLOOD-LETTING THERAPY

The author used the pricking-blood therapy to treat 14 cases of laryngeal car-buncle.The pricking-blood therapy included clumpy pricking(local area),spot pricking(prickingSanshang points on the thumb and three points of the helix).The therapy has role of clearing awaypathogentic heat and toxic materials and promoting subsidence of swelling.It could avoid forming py-opoiesis and free from operating treatment.The treatment was given once daily,result:13 cases cured(93%),1 case failed(7%).In 14 cases,antero-upper type has 13 cases which cured,postero-uppertype has only 1 case which treated failure.It is because its imflammation was located on posterior totonsillae,exposed bad and pricked difficulty.So the therapy only used antero-upper type of laryngealcarbuncle and had a good effect.

Effects of pricking blood therapy at meridian sinews on upper limb spasm of post-stroke patients

Objective:To observe effects of pricking blood therapy at meridian sinews on upper limb spasm of poststroke patients.Methods:A total of 72 patients with post-stroke upper limb spasm were randomly divided into a comprehensive group of pricking blood therapy at meridian sinews with rehabilitation training(comprehensive group)and the simple rehabilitation training group(rehabilitation group),and there were 36 patients in each group.On the basis of routine therapy,the patients of the two groups received rehabilitation therapy for 6 consecutive days and 1-day rest,for 4 weeks in total.On the above basis,the patients in the comprehensive group received pricking blood therapy at meridian sinews,once every other day,3 times per week,for 4 weeks in total.Before treatment,after the first treatment,and after 4-week treatment,the patients were observed for changes of upper limb spasticity(Modified Ashworth Scale,MAS),upper limb movement function(Fugl-Meyer Assessment,FMA),activity of daily living(Modified Barthel Index,MBI),and biceps and triceps integrated electromyogram(IEMG)values were observed as well as the therapeutic effects.Results:(1)After the first treatment,there were statistically significant differences of the MAS scale grades in patients of the two groups(P<0.05).The FMA scores in the comprehensive group were increased than that before treatment(P<0.05),and the MBI scores of the two groups were increased than those before treatment(both P<0.05).The FMA and MBI scores in the comprehensive group were higher than those of the rehabilitation group(both P<0.05).The biceps and triceps IEMG values were not improved than those before treatment(all P>0.05).(2)After 4-week treatment,there were statistically significant differences of MAS grades in patients of the two groups(P<0.05).The FMA and MBI scores in the two groups were increased than those before treatment(all P<0.05),and the FMA and MBI scores in the comprehensive group were higher than those in the rehabilitation group(both P<0.05).Through comparison of the differences of FMA and MBI scores of the two groups,the difference values in the comprehensive group were higher than those of the rehabilitation group(both P<0.05).The biceps and triceps IEMG values in the two groups were decreased than those before treatment(all P<0.05),and those in the comprehensive group were lower than those in the rehabilitation group(both P<0.05).The biceps and triceps IEMG values in patients of the comprehensive group were higher than those before treatment(both P<0.05).(3)After 4-week treatment,the total effective rate in the comprehensive group was 83.3%(30/36),and that was 58.3%(21/36)in the rehabilitation group.The total effective rate in the comprehensive group was higher than that in the rehabilitation group(P<0.05).Conclusions:The pricking blood therapy at meridian sinews can release affected upper limb flexor muscle spasticity and movement function of the patients with post-stroke upper limb spasm,decrease biceps IEMG values of the affected side,and improve activities of daily living.

Clinical Observation on Pricking Bloodletting Therapy at Back-Shu Acupoints Plus Chinese Herbal Mask in Treating Patients with Acne

Objective： To observe the clinical efficacy on pricking bloodletting and cupping therapy combined with Chinese herbal mask in treating acne. Methods： Thirty-seven patients with ache were randomly divided into a treatment group （treated by pricking bloodletting and cupping therapy combined with Chinese herbal mask） and a control group （only by Chinese herbal mask）. The therapeutic efficacy was observed after 2-course treatment. Results： The total effective rate in the treatment group was 94.7% versus 61.1% in the control group. According to the statistical management, the total effective rate in the treatment group was significantly higher than that in the control group （P〈O.05）. Conclusion： Pricking bloodletting and cupping therapy combined with Chinese herbal mask therapy for acne is more effective than Chinese herbal mask treatment alone.

Effect of Pricking Blood Therapy on Behavior and Gene Expression in a Rat Model of Migraine

Objective： To investigate the effect of pricking blood therapy on behavior and brainstem c-los and c-jun gene expression in migraine rats. Methods： A rat model of migraine was made with nitroglycerol. The rats were treated by pricking blood. Rat behavior was observed. Brainstem c-fos and c-jun gene expression was examined by immunohistochemistry. Results： Ear redness improved significantly, the number of head scratchings decreased obviously （P〈0.05） and c-fos and c-jun expression was reduced markedly （P〈0.01） in the treatment group after pricking blood compared with the model group and the blank group. Conclusion： Pricking blood treatment can improve behavior indices and reduce c-fos and c-jun positive expression in migraine rats.

刺血疗法配合针刺调控炎症因子治疗急性期Bell麻痹疼痛患者的临床观察

目的:观察刺血疗法配合针刺治疗对Bell麻痹急性期疼痛患者的疗效及对患者血清细胞因子白介素-1β(Interleukin-1β,IL-1β)和肿瘤坏死因子(Tumor Necrosis Factor-α,TNF-α)的影响。方法:收集100例急性面瘫疼痛患者,随机分为观察组、对照组,各50例。其中观察组患者的治疗主要包括两个阶段:急性期治疗和恢复期治疗。急性期治疗运用刺血、常规针刺相配合的治疗方式,针刺穴位一般为常规取穴如地仓穴、下关穴等,刺血穴位选用阳白穴、太阳穴、颧髎穴、大椎穴;恢复期时,主要应用针刺法进行治疗。对照组患者仅运用针刺法进行治疗。10 d为1个疗程,共观察3个疗程。对两组患者治疗前后的各项参数变化情况进行详细记录,如急性期疼痛持续时间、总体治疗效果等,并测定两组患者血清IL-1β、TNF-α水平。结果:观察组疼痛视觉模拟评分法评分及面神经功能评分均明显优于对照组(P<0.01),而在疼痛持续时间、病程方面,相较于对照组患者,观察组相对更优(P<0.01),在总体治疗效果方面,观察组的治疗效果更好(P<0.05)。两组患者治疗后IL-1β、TNF-α的值较治疗前均明显减少(P<0.05),且观察组IL-1β、TNF-α减少程度较对照组明显(P<0.05)。结论:对于急性期Bell麻痹伴有疼痛的患者,运用刺血疗法加针刺治疗能够明显减轻患者的耳后疼痛,使患者的治疗周期缩短,治疗效果提升,同时可以快速减轻神经损伤,提高临床疗效。

Treatment of Herpes Zoster with Electroacupuncture plus Collateral-pricking and Cupping Therapy

Objective： To observe the clinical effect of electroacupuncture （EA） plus collateral-pricking and cupping therapy for herpes zoster. Methods： Fifty-three cases with herpes zoster were randomly divided into two groups. Thirty-one cases in the treatment group were treated with EA at Jiaji （EX-B 2） points plus local collateral-pricking and cupping therapy. Twenty-two cases in the control group were treated with oral administration of VaLacido~;ir Hvdrochloride and Indomethaci~. Results： The curative and remarkable effective rate was 93.5% in the treatment group and 72.7% in the control group. The difference between the two groups was statistically significant （P〈0.01）, indicating that EA plus collateral-pricking and cupping therapy is better than Western medications in the clinical effects for herpes zoster. Conclusion： The EA plus collateral-pricking and cupping method is an effective therapy for herpes zoster.

Muscle regions of meridians warm needling method plus pricking Jing-Well points for blood-letting in the treatment of shoulder-hand syndrome after stroke

Objective To observe the effect of muscle regions of meridians warm needling method plus pricking Jing-Well points for blood-letting in improving nail fold microcirculation in the patients with shoulder-hand syndrome(SHS)after stroke,and the effects on hemorrheology,calcitonin gene-related peptide(CGRP)and serum substance P(SP).Methods A total of 72 patients were randomized into an observation group and a control group by the random number table method,with 36 cases in each group.The control group was treated with physical rehabilitation training,and the observation group was treated with additional muscle regions of meridians warm needling method plus pricking Jing-Well points for blood-letting treatment.The treatment course lasted for 4 weeks.After treatment,the clinical efficacy of the two groups was compared.The changes in shoulder-hand syndrome scale(SHSS),simplified Fugl-Meyer assessment-upper extremity(FMA-UE),visual analog scale(VAS),activities of daily living(ADL),traditional Chinese medicine(TCM)syndrome score,nail fold microcirculation hemorheology indictors[whole blood viscosity(high-shear,low-shear),hematocrit,erythrocyte sedimentation rate(ESR)],CGRP and SP levels were observed.Results The total effective rate in the observation group was 86.1%,higher than 63.9%in the control group(P<0.05).The overall curative effect in the observation group was better than that in the control group(P<0.05).After treatment,the scores of pain sensation,edema,external turn and rotation of the arm in SHSS,and the total score were significantly decreased in both groups(all P<0.05),and each score in the observation group was lower than that in the control group(all P<0.05).After treatment,the scores of VAS and TCM syndrome in both groups decreased significantly(all P<0.05),and the scores of FMA-UE and ADL increased significantly(all P<0.05).The scores of VAS and TCM syndrome in the observation group were lower than those in the control group(both P<0.05),and the scores of FMA-UE and ADL were higher than those in the control group(both P<0.05).After treatment,the whole blood viscosity(high-shear and low-shear)and hematocrit in both groups decreased obviously(all P<0.05),and ESR increased obviously(both P<0.05),and the whole blood viscosity(high-shear and low-shear)and hematocrit in the observation group were lower than those in the control group(all P<0.05),and ESR was higher than that in the control group(P<0.05).After treatment,the peritubular state,loop shape,blood flow and total score of nail fold microcirculation in both groups decreased significantly(all P<0.05),and each score in the observation group was lower than that in the control group(all P<0.05).After treatment,SP in both groups decreased obviously(both P<0.05),CGRP increased obviously(both P<0.05),and SP in the observation group was lower than that in the control group(P<0.05),CGRP was higher than that in the control group(P<0.05).Conclusion Compared with conventional physical rehabilitation training,muscle regions of meridians warm needling method plus pricking Jing-Well points for blood-letting treatment can significantly reduce the clinical symptoms of SHS,promote the recovery of physical functions,improve the nail fold microcirculation and hemorrheology indictors,and regulate the serum cytokine levels such as CGRP and SP.

朱维平基于少阴伏邪理论内外并治干燥综合征干眼经验

文章总结朱维平教授自拟方加味鳖甲散联合耳部刺络放血疗法内外并治干燥综合征干眼经验。朱维平教授提出内外并治干燥综合征所致干眼,综合考虑了干燥综合征患者正气亏虚,少阴伏邪,精亏血枯致瘀而燥的发病特点,提出基于少阴伏邪理论治疗干燥综合征干眼,认为正气亏虚是伏邪致燥的基础,邪伏少阴是内在核心致病因素,继而感受外邪,内外相合而发病。临床上常在中药汤剂加味鳖甲散透邪救阴、扶正养阴的基础上重视祛瘀通络,联合刺血疗法治疗干燥综合征所致干眼,认为邪祛一分、正缓一分,使邪祛正缓,临床疗效显著。文章简述“少阴伏邪”理论,以干燥综合征干眼的病因病机为切入点,结合刺络放血疗法的治疗优势,对朱维平教授治疗干燥综合征干眼的理论和临床经验进行介绍,并举验案一则,以期为临床治疗干燥综合征干眼提供具有参考意义的诊疗思路。

Efficacy and safety of blood pricking and cupping for treating nonspecific low back pain: a systematic review and Meta-analysis

OBJECTIVE: To systematically evaluate the efficacy and safety of blood pricking and cupping in the treatment of nonspecific low back pain(NLBP).METHODS:The China National Knowledge Infrastructure Database(CNKI), Wanfang Med Online Database(Wanfang), China Science and Technology Journal Database(VIP), Pub Med, Web of Science,EMBase, and Cochrane Library databases were searched from inception to October 31, 2021, for randomized controlled trials(RCTs) of the treatment of NLBP by blood pricking and cupping. The quality of each included study was evaluated according to the Cochrane Systematic Assessor’s Manual evaluation criteria, while the Meta-analysis was performed using RevMan 5.4software.RESULTS: A total of 13 thirteen RCTs included a total of 1088 subjects. The visual analogue scale scores indicated that blood pricking and cupping was superior to the other treatments at relieving NLBP pain [mean difference(MD) =-1.43;95% confidence interval(CI):-2.31 to 0.54;Z = 3.15;P = 0.002). The Oswestry Disability Index score of blood pricking and cupping was superior to that of the control group in terms of improving NLBP dysfunction(MD =-6.25;95%CI:-8.37 to-4.31);Z = 5.77;P < 0.000 01). 7 RCTs mentioned no adverse reactions, while one study reported mild syncope [7%(n = 3), all in the 17-30 years group] that was gradually relieved after rest. CONCLUSIONS: Blood pricking and cupping therapy can safely and effectively reduce pain and improve functional impairment in patients with NLBP. However, this study included limited high-grade studies with a small overall sample size;therefore, further high-quality large-sample RCTs are needed to improve clinical evidence.

刺血加温针灸治疗痛风性关节炎临床观察

目的 探讨刺血加温针灸对痛风性关节炎患者临床疗效、炎症指标及尿酸水平的影响。方法 2020年3月-2022年3月万安县中医院共计收治66例痛风性关节炎患者,随机等分为对照组与观察组,各33例。对照组患者予常规西药治疗,观察组患者予刺血加温针灸治疗。对比2组临床治疗效果、炎症指标及尿酸水平。结果 观察组总有效率为97.0%(32/33),高于对照组的66.7%(22/33),差异有统计学意义(P<0.05)。治疗后,观察组血沉、C反应蛋白(CRP)均低于对照组,差异有统计学意义(P<0.05)。观察组尿酸水平低于对照组,差异均有统计学意义(P<0.05)。结论 刺血加温针灸治疗痛风性关节炎患者,临床效果显著,可降低患者的炎症指标和尿酸水平,应用价值高。

自拟退热汤加减联合刺血疗法治疗社区获得性肺炎33例

目的观察自拟退热汤加减联合刺血疗法治疗肺炎的疗效。方法64例社区获得性肺炎患者,随机分为治疗组(33例)和对照组(31例)。对照组按社区获得性肺炎治疗指南常规采用抗感染、祛痰等治疗方法进行治疗,治疗组在对照组综合治疗基础上加用自拟退热汤联合刺血疗法进行治疗。比较两组体温恢复正常时间,治疗前、治疗第3天、治疗第6天白细胞计数、C反应蛋白,疗效。结果治疗组体温恢复正常时间(46.56±16.51)h短于对照组的(58.84±18.14)h(P<0.05)。治疗第6天,两组白细胞计数、C反应蛋白水平均低于本组治疗前、治疗第3天,且治疗组白细胞计数(9.32±1.37)×10^(9)/L、C反应蛋白(15.23±9.20)mg/L低于对照组的(11.20±1.88)×10^(9)/L、(22.58±13.27)mg/L(P<0.05)。治疗组总显效率72.7%高于对照组的48.4%(P<0.05)。结论自拟退热汤加减联合刺血疗法能促进社区获得性肺炎患者体温、白细胞计数和C反应蛋白水平恢复,以及肺部炎症渗出吸收,提高临床疗效。

基于数据挖掘的刺络拔罐疗法临床应用特点研究

目的:研究刺络拔罐疗法在相关文献中的临床应用特点,为临床使用刺络拔罐治疗疾病提供参考。方法:运用计算机和数据挖掘技术,建立“刺络拔罐疗法临床应用特点数据库”,利用数据挖掘技术对相关文献进行收集、筛选、审核、整理、提取和录入并进行统计分析。结果:刺络拔罐疗法在临床运用中以皮肤科最多,外科、内科、妇科次之,五官科、儿科应用较少,其中以带状疱疹应用居多;刺络拔罐应用腧穴多以阿是穴、督脉和足太阳膀胱经穴为主;工具多选三棱针和玻璃罐;针刺深度一般为0.1~0.5 cm,放血量一般为1~5 mL,留罐10 min后取罐;刺络拔罐常配合毫针刺法使用效果更佳;治疗频次大多2~3 d 1次,多数疾病在1个月内治疗6~10次有效率可达到90%以上。结论:本研究发现带状疱疹是刺络拔罐疗法的优势病种,在临床其操作方法也有一定特点。

制污穴刺血疗法联合四妙汤加减治疗3、4期压力性损伤疗效观察及对肉芽组织生长因子的影响

目的:观察制污穴刺血疗法联合四妙汤加减治疗3、4期压力性损伤的疗效及对肉芽组织生长因子的影响。方法:选取120例3、4期压力性损伤患者,按随机数字表法分为对照组及观察组各60例。对照组接受常规治疗,观察组在对照组基础上采用制污穴刺血疗法联合四妙汤加减治疗。比较2组临床疗效及不良反应发生情况,比较2组治疗前后Bates-Jensen伤口评估与效果评价量表(BWAT)评分、肉芽组织出现时间、肉芽覆盖创面时间、肉芽组织生长因子[转化生长因子-β1(TGF-β1)、基质金属蛋白酶(MMP-9)、血管内皮生长因子(VEGF)]的变化。结果:观察组临床疗效总有效率为98.33%,对照组为86.67%,2组临床疗效比较,差异有统计学意义(P<0.05)。治疗后,2组BWAT评分均较治疗前下降(P<0.05),观察组BWAT评分低于对照组(P<0.05)。观察组肉芽组织出现时间、肉芽覆盖创面时间均短于对照组,差异均有统计学意义(P<0.05)。治疗后,2组TGF-β1、VEGF指标值均较治疗前升高(P<0.05),MMP-9指标值均较治疗前下降(P<0.05);观察组TGF-β1、VEGF指标值均高于对照组(P<0.05),MMP-9指标值低于对照组(P<0.05)。治疗期间,2组均无明显不良反应发生。结论:制污穴刺血疗法联合四妙汤加减治疗3、4期压力性损伤疗效较好,可缩短肉芽组织出现时间及肉芽覆盖创面时间,促进肉芽组织生长,有利于快速恢复。

点刺“委中”放血对实验性腰椎间盘突出症坐骨神经传导速度和髓核组织白细胞介素-1α的影响

目的:通过观察实验性腰椎间盘突出症(lumbar intervertebral disc protrusion,LIDP)家兔坐骨神经传导速度(sciatic nerve conduction velocity,SNCV)和髓核组织中白细胞介素-1α(interleukin-1α,IL-1α)水平变化,探讨点刺"委中"放血治疗LIDP的机制。方法:40只健康新西兰家兔随机分为4组,即空白组、LIDP模型组、点刺委中组和点刺非穴对照点组。自制的LIDP动物病理模型造模器造实验性LIDP病理模型,三棱针点刺"委中"或对照点放血治疗,左右交替,连续7 d。采用BL-410生理信号记录系统记录SNCV,酶联免疫吸附法测定腰椎间盘髓核组织中IL-1α的含量。结果:点刺委中组治疗后SNCV显著高于治疗前(P<0.01),其治疗前后SNCV的差值显著高于模型组和非穴对照组(P<0.05);点刺"委中"放血可降低LIDP家兔髓核组织中IL-1α含量,与模型组和非穴对照组比较差异有显著性意义(P<0.01,0.05)。结论:点刺"委中"穴可明显增快LIDP家兔的SNCV,减少IL-1α等炎症因子含量以减轻炎症反应可能是点刺"委中"放血治疗LIDP的机制之一。

火针配合刺络拔罐治疗神经性皮炎疗效观察

目的:探寻治疗神经性皮炎的有效疗法。方法:按随机数字表法将96例患者分为两组,火针刺皮损区皮肤配合刺络拔罐54例为治疗组,澳能(卤米松乳膏)外擦皮损42例为对照组,分别进行治疗。结果:治疗组治愈率为51.9%,总有效率为96.3%;对照组治愈率为28.6%,总有效率为81.0%。经统计学处理,两组疗效差异具有显著性意义(P<0.05)。结论:火针配合刺络拔罐治疗神经性皮炎疗效确切,无毒副作用,操作简便易行,值得推广。

刺血疗法治疗急性痛风性关节炎90例对照研究

目的 :观察刺血疗法不同刺血量及西药治疗急性痛风性关节炎的疗效 ,并探讨其作用机理。方法 :将 90例急性痛风性关节炎患者随机分成A组、B组、C组 ,分别采用点刺穴位放血 5mL、10mL及内服西药 3种方法治疗。结果 :B组止痛效果最好 ,疗效优于其它两组 ;B组与C组降血尿酸效果与A组相比 ,差异具有非常显著性意义 (P <0 0 1) ,B组与C组差异无显著性意义 (P >0 0 5 ) ;B组与其它两组降尿尿酸效果相比 ,差异有非常显著性意义 (P <0 0 1)。结论 :刺血疗法是治疗急性痛风性关节炎的有效方法 ,疗效与出血量有关 ,其作用机制是通过抑制血尿酸的合成 ,促进尿尿酸排泄 ,发挥其疗效。

刺血疗法对急性痛风性关节炎模型局部关节软骨超微结构的影响

目的观察刺血疗法对于急性痛风性关节炎大鼠模型的局部症状、光镜下形态学改变、电镜下超微结构改变的影响,初步探索刺血疗法治疗本病的效应机制。方法 40只SD大鼠随机分为正常组、模型组、药物组、刺血组。通过右踝关节腔注射尿酸钠建立急性痛风性关节炎模型。药物组以布洛芬灌胃治疗,刺血组在右侧昆仑穴刺血。测量4组4个时间点的造模踝关节的周径,光镜下观察造模后关节腔组织形态学改变,电镜观察软骨组织的超微结构。结果刺血组24h后造模踝关节周径与药物组、模型组比较,差异有统计学意义(P<0.05);48h后与药物组、正常组比较,差异无统计学意义(P>0.05)。光镜结果显示:模型组关节腔内有尿酸钠结晶沉积,并有大量炎细胞浸润;药物组关节腔内有部分尿酸钠结晶沉积,并有部分炎细胞浸润;刺血组关节腔内有少量粉色团块状物体沉积,及少量炎细胞浸润。电镜结果显示:模型组细胞有渗出,突起,胶原纤维排列乱且密集;药物组细胞有渗出,突起,胶原纤维排列紊乱;刺血组细胞结构正常,胶原纤维排列较乱。结论刺血疗法能有效快速地减轻关节腔尿酸钠的沉积,减少炎细胞的浸润,改善关节软骨的超微结果,改善局部症状。与常规的药物疗法比较,有疗效好、起效快、毒副作用小的优势,值得推广。

刺血疗法治疗痛风性关节炎23例对照观察

采用刺血疗法治疗痛风性关节炎,观察治疗前后临床症状、血尿酸、尿尿酸及 RNA 酶的变化。结果表明:刺血纽有效率100.00%,痛风灵组有效率75.00%,西药组有效率68.43%。其理化指标亦有明显变化,经统计学处理有显著意义。提示刺血能促进尿尿酸排泄,抑制血尿酸的合成,促进患者免疫功能趋向正常,使机体对嘌呤类代谢起调节作用,达到治疗目的。