Since 2014,nationwide reading has been included in the government work report for 10 consecutive times,and twice into the country’s five-year development plan.The importance of reading for individuals,society,and the...Since 2014,nationwide reading has been included in the government work report for 10 consecutive times,and twice into the country’s five-year development plan.The importance of reading for individuals,society,and the country has become increasingly prominent.National reading has flourished,and throughout the 2018 to 2022 National Reading Survey Report,there have been welcome changes in national reading in China.This study compares and analyzes the relevant reading indicators of adult nationals from 2018 to 2022,and summarizes the five changes and new trends in national reading.That is,national reading awareness has increased,paper-book reading habits have returned,digital reading has become more diversified,the listening group has grown,and the voice of national reading activities has continued to rise.Accordingly,it provides relevant development strategies for publishers.展开更多
As suggested by the title, this extensive book is concerned with crack and contact prob- lems in linear elasticity. However, in general, it is intended for a wide audience ranging from engineers to mathematical physic...As suggested by the title, this extensive book is concerned with crack and contact prob- lems in linear elasticity. However, in general, it is intended for a wide audience ranging from engineers to mathematical physicists. Indeed, numerous problems of both academic and tech- nological interest in electro-magnetics, acoustics, solid and fluid dynamics, etc. are actually related to each other and governed by the same mixed boundary value problems from a unified mathematical standpoint展开更多
In 2012, the first paper in the series Analytical Methods in Quality Control of Scientific Publications was published in the American Journal of Analytical Chemistry, Vol. 3, No. 6, 2012, pp. 443-447. This paper was m...In 2012, the first paper in the series Analytical Methods in Quality Control of Scientific Publications was published in the American Journal of Analytical Chemistry, Vol. 3, No. 6, 2012, pp. 443-447. This paper was mainly based on evidence presented in the 2011 in book Historical Overview of Chromatography and Related Techniques in Analysis of Antimalarial Drug Primaquine (editor Ilia Brondz, Nova Science Publishers, Inc., ISSN 978-1-61761-944-1). The first paper in this series di- scussed issues of obvious falsification and plagiarism contained in paper published by Dongre et al., Applications of GC-EI-MS for the Identification and Investigation of Positional Isomer in Primaquine, an Antimalarial Drug. Journal of Pharmaceutical and Biomedical Analysis, Vol. 39, No. 1-2, 2005, pp. 111-116. Dongre et al. copied their publication from an original research manuscript submitted for consideration by other authors. This paper was published in the Asian Journal of Chemistry, Vol. 17, No. 3, 2005, pp. 1678-1688. Conclusive arguments against the publication of Dongre et al. were presented in the American Journal of Analytical Chemistry, Vol. 3, No. 6, 2012, pp. 443-447. Further cases of general plagiarism and incompetence relating to authors, reviewers, editors, and publishers were presented in Part II in Analytical Methods in Quality Control of Scientific Publications Part II: The Authors’, Reviewers’, Editors’ Responsibility and the Publishers’ Authority in the International Journal of Analytical Mass Spectrometry and Chromatography, Vol. 1, No. 2, 2013, pp. 81-89. The present paper will discuss the following issues: the obvious neglect of the rights of authors by some publishers and editors;how original research manuscripts are exposed to mediocre researchers, and possibly sold, by editors to these “scientists” to boost the image of these particular “scientists”;how the order of authors’ names in published articles are changed to satisfy the commercial interests of companies;and how copyright is breached in an appalling way by well-established publishers. The documents presented here concern research publications in the fields of chromatography, chromatography-mass spectrometry, and mass spectrometry.展开更多
From March 12 to 14,2024,the London Book Fair was held at the Olympia Exhibition Centre in London.The fair attracted over 1,000 publishing organizations and more than 30,000 publishing professionals from around the wo...From March 12 to 14,2024,the London Book Fair was held at the Olympia Exhibition Centre in London.The fair attracted over 1,000 publishing organizations and more than 30,000 publishing professionals from around the world.Chinese publishing entities promoted fine Chinese books and culture through book displays,multimedia presentations,and exchanges between Chinese and foreign experts,enhancing publishing cooperation and cultural exchange.展开更多
[目的/意义]对Open Book Publishers(OBP)出版社学术图书开放获取商业模式的9个构成要素及运作特点展开研究,以期以更细粒化的商业模式研究视角,求解破除图书开放获取困局的办法,并为以学术团体或大学研究机构为主导的同类出版社建立可...[目的/意义]对Open Book Publishers(OBP)出版社学术图书开放获取商业模式的9个构成要素及运作特点展开研究,以期以更细粒化的商业模式研究视角,求解破除图书开放获取困局的办法,并为以学术团体或大学研究机构为主导的同类出版社建立可持续的商业模式提供参考。[方法/过程]从开放获取的研究视角,运用商业画布分析工具及案例分析法,试探究OBP出版社的商业模式构成要素及其耦合机理。[结果/结论]OBP作为全开放出版社能实现微利,其秘籍在于以用户需求为导向,以平台为基础,在明确的客户细分、面向用户需求的价值主张、良好的客户关系、畅通的渠道通路、丰富的内容资源与合作伙伴基础等要素的基础上,实现了供给侧与需求侧的精准匹配,引导实现正向网络外部性效应与聚集效应。OBP商业模式的成功也为我国开展图书开放获取活动提供了有益的启示。展开更多
Purpose:This study aims to explore the geography of editors-in-chief to demonstrate which countries exercise the highest-level decision-making in scholarly communication.In addition,the study seeks to investigate the ...Purpose:This study aims to explore the geography of editors-in-chief to demonstrate which countries exercise the highest-level decision-making in scholarly communication.In addition,the study seeks to investigate the potential relationships between the origin and nationality of academic publishers and the geography of editors-in-chief.Design/methodology/approach:The analysis involves 11,915 journals listed in Web of Science’s Social Sciences Citation Index(SSCI)and Science Citation Index Expanded(SCIE).These journals employ 15,795 scholars as editors-in-chief.The geographical locations of the institutions the editors-in-chief are affiliated with were identified;then,the data were aggregated at the country level.Findings:The results show that most editors-in-chief are located in countries of the Anglosphere,primarily the United States and the United Kingdom.In addition,most academic publishers and professional organizations that publish academic journals were found to be based in the United States and the United Kingdom,where most editors-in-chief are also based.Research limitations:The analysis involves journals indexed in the Web of Science’s SCIE/SSCI databases,which are demonstrably biased toward the English language.Furthermore,the study only takes a snapshot of the geography of editors-in-chief for the year 2022,but it does not investigate trends.Research implications:The study maps the highest-level decision-making in scholarly communication.Originality/value:The study explores and maps the geography of editors-in-chief by using a massive dataset.展开更多
Over the years immunotherapy has demonstrably improved the field of cancer treatment.However,achieving long-term survival for colorectal cancer(CRC)patients remains a significant unmet need.Combination immunotherapies...Over the years immunotherapy has demonstrably improved the field of cancer treatment.However,achieving long-term survival for colorectal cancer(CRC)patients remains a significant unmet need.Combination immunotherapies incor-porating targeted drugs like MEK or multi-kinase inhibitors have offered some palliative benefit.Nevertheless,substantial gaps remain in the current therapeutic armamentarium for CRC.In recent years,there has been a surge of interest in exploring novel treatment strategies,including the application of light-activated drugs in conjunction with optical devices.This approach holds promise for achie-ving localized and targeted delivery of cytotoxic agents,such as microtubule-targeting drugs,directly to cancerous cells within the colon.展开更多
INTRODUCTION,Types of paper,Submission Checklist,BEFORE YOU BEGIN,Ethics in publishing,Ethics Consent,Publication Consent,Studies in humans and animals,Declaration of interest,Submission declaration and verification,U...INTRODUCTION,Types of paper,Submission Checklist,BEFORE YOU BEGIN,Ethics in publishing,Ethics Consent,Publication Consent,Studies in humans and animals,Declaration of interest,Submission declaration and verification,Use of inclusive language,Preprints,Authors contributions,Changes to authorship。展开更多
BACKGROUND The annual incidence of metabolic-associated fatty liver disease(MAFLD)in China has been increasing and is often overlooked owing to its insidious charac-teristics.Approximately 50%of the patients have a no...BACKGROUND The annual incidence of metabolic-associated fatty liver disease(MAFLD)in China has been increasing and is often overlooked owing to its insidious charac-teristics.Approximately 50%of the patients have a normal weight or are not obese.They are said to have lean-type MAFLD,and few studies of such patients are available.Because MAFLD is associated with abnormal lipid metabolism,lipid-targeted metabolomics was used in this study to provide experimental evidence for early diagnosis and pathogenesis.MAFLD and analyze metabolic pathways.UPLC-Q-Orbitrap/MS content determination was used to determine serum palmitic acid(PA),oleic acid(OA),linoleic acid(LA),and arachidonic acid(AA)levels in lean-type MAFLD patients.RESULTS Urea nitrogen and uric acid levels were higher in lean-type MAFLD patients than in healthy individuals(P<0.05).Alanine transaminase and cholinesterase levels were higher in lean-type MAFLD patients than in healthy indi-viduals(P<0.01).The expression of high-density lipoprotein and apolipoprotein A-1 were lower in lean-type MAFLD patients than in healthy individuals(P<0.05)and the expression of triglycerides and fasting blood glucose were increased(P<0.01).A total of 65 biomarkers that affected the synthesis and metabolism of fatty acids were found with P<0.05 and variable importance in projection>1.The levels of PA,OA,LA,and AA were significantly increased compared with healthy individuals.CONCLUSION The metabolic profiles of lean-type MAFLD patients and healthy participants differed significantly,yielding 65 identified biomarkers.PA,OA,LA,and AA exhibited the most significant changes,offering valuable clinical guidance for prevention and treatment of lean-type MAFLD.展开更多
BACKGROUND Heart failure(HF),a common cardiovascular condition,is characterized by significant morbidity and mortality.While traditional Chinese medicine(TCM)is often used as a complementary approach in HF management,...BACKGROUND Heart failure(HF),a common cardiovascular condition,is characterized by significant morbidity and mortality.While traditional Chinese medicine(TCM)is often used as a complementary approach in HF management,systematic evalua-tions of its impact on clinical outcomes,TCM syndrome scores,and B-type natriuretic peptide(BNP)levels are lacking.This study fills this gap through a comprehensive analysis of randomized controlled trials(RCTs)focusing on TCM for HF treatment.It encompasses an assessment of methodological quality,a meta-analysis,and an evaluation of evidence quality based on established standards.The results offer crucial insights into the potential advantages and constraints of TCM in HF management.RCTs on TCM for HF treatment published since the establishment of the database were searched in four Chinese and English databases,including China National Knowledge Infrastructure,Wanfang,VIP Information Chinese Science and Technology Journal,and PubMed.Methodological quality was assessed for the included studies with the Cochrane risk-of-bias assessment tool,and the meta-analysis and publication bias assessment was performed with the RevMan5.3 software.Finally,the quality of evidence was rated according to the GRADE criteria.RESULTS A total of 1098 RCTs were initially retrieved.After screening,16 RCTs were finally included in our study,which were published between 2020 and 2023.These RCTs involved 1660 HF patients,including 832 in the TCM group[TCM combined with conventional Western medicine(CMW)treatment]and 828 in the CWM group(CWM treatment).The course of treatments varied from 1 wk to 3 months.TCM syndrome differentiation was analyzed in 11 of the included RCTs.In all included RCTs,outcome indicators included comprehensive clinical outcomes,TCM syndrome scores,and BNP levels.The meta-analysis results showed significant differences between the TCM and CWM groups in terms of comprehensive clinical outcomes[risk ratio=-0.54;95%confidence interval(CI)=-0.61,-0.47;P<0.00001],TCM syndrome scores[weighted mean difference(WMD)=-142.07;95%CI=-147.56,-136.57;P<0.00001],and BNP levels(WMD=-142.07;95%CI=-147.56,-136.57;P<0.00001).According to the GRADE criteria,RCTs where"TCM improves clinical comprehensive outcomes"were rated as low-quality evidence,and RCTs where"TCM reduces TCM syndrome scores"or"TCM decreases BNP levels"were rated as medium-quality evidence.CONCLUSION TCM combined with CWM treatment effectively improves comprehensive clinical outcomes and diminishes TCM syndrome scores and BNP levels in HF patients.Given the low and medium quality of the included RCTs,the application of these results should be cautious.展开更多
The overgeneralisation may happen because most studies on data publishing for multiple sensitive attributes(SAs)have not considered the personalised privacy requirement.Furthermore,sensitive information disclosure may...The overgeneralisation may happen because most studies on data publishing for multiple sensitive attributes(SAs)have not considered the personalised privacy requirement.Furthermore,sensitive information disclosure may also be caused by these personalised requirements.To address the matter,this article develops a personalised data publishing method for multiple SAs.According to the requirements of individuals,the new method partitions SAs values into two categories:private values and public values,and breaks the association between them for privacy guarantees.For the private values,this paper takes the process of anonymisation,while the public values are released without this process.An algorithm is designed to achieve the privacy mode,where the selectivity is determined by the sensitive value frequency and undesirable objects.The experimental results show that the proposed method can provide more information utility when compared with previous methods.The theoretic analyses and experiments also indicate that the privacy can be guaranteed even though the public values are known to an adversary.The overgeneralisation and privacy breach caused by the personalised requirement can be avoided by the new method.展开更多
In 2023,Baishideng Publishing Group(Baishideng)routinely published 47 openaccess journals,including 46 English-language journals and 1 Chinese-language journal.Our successes were accomplished through the collective de...In 2023,Baishideng Publishing Group(Baishideng)routinely published 47 openaccess journals,including 46 English-language journals and 1 Chinese-language journal.Our successes were accomplished through the collective dedicated efforts of Baishideng staffs,Editorial Board Members,and Peer Reviewers.Among these 47 Baishideng journals,7 are included in the Science Citation Index Expanded(SCIE)and 6 in the Emerging Sources Citation Index(ESCI).With the support of Baishideng authors,company staffs,Editorial Board Members,and Peer Reviewers,the publication work of 2023 is about to be successfully completed.This editorial summarizes the 2023 activities and accomplishments of the 13 SCIEand ESCI-indexed Baishideng journals,outlines the Baishideng publishing policy changes and additions made this year,and highlights the unique advantages of Baishideng journals.展开更多
Journal of Acute Disease(JAD)is a bimonthly international medical journal dedicated to promoting and disseminating original,peer-reviewed work in the field of acute attack of all kinds of diseases,including pre hospit...Journal of Acute Disease(JAD)is a bimonthly international medical journal dedicated to promoting and disseminating original,peer-reviewed work in the field of acute attack of all kinds of diseases,including pre hospital and hospital emergency medicine,disaster medicine,critical diseases,acute diseases and related medical specialties by publishing high quality scientific and clinical research worldwide.展开更多
Visual media have dominated sensory communications for decades,and the resulting“visual hegemony”leads to the call for the“auditory return”in order to achieve a holistic balance in cultural acceptance.Romance of t...Visual media have dominated sensory communications for decades,and the resulting“visual hegemony”leads to the call for the“auditory return”in order to achieve a holistic balance in cultural acceptance.Romance of the Three Kingdoms,a classic literary work in China,has received significant attention and promotion from leading audio platforms.However,the commercialization of digital audio publishing faces unprecedented challenges due to the mismatch between the dissemination of long-form content on digital audio platforms and the current trend of short and fast information reception.Drawing on the Business Model Canvas Theory and taking Romance of the Three Kingdoms as the main focus of analysis,this paper argues that the construction of a business model for the audio publishing of classical books should start from three aspects:the user evaluation of digital audio platforms,the establishment of value propositions based on the“creative transformation and innovative development”principle,and the improvement of the audio publishing infrastructure to ensure the healthy operation and development of the digital audio platforms and consequently improve their current state of development and expand the boundaries of cultural heritage.展开更多
The paper is based on literature search,introducing and analyzing the book publishing situation of modern Peking University Library from the perspective of the publisher being Peking University Library and its predece...The paper is based on literature search,introducing and analyzing the book publishing situation of modern Peking University Library from the perspective of the publisher being Peking University Library and its predecessor.It is pointed out that the majority of the book printing methods published by the modern Peking University Library are lead printing,and among the types of Chinese library classification,catalogue of library collections is the most common.展开更多
Many modern Chinese libraries have established distribution agencies in other cities to distribute books published or sold on consignment.Huating Bookstore,which was once the Shanghai General Distribution Office of Zh...Many modern Chinese libraries have established distribution agencies in other cities to distribute books published or sold on consignment.Huating Bookstore,which was once the Shanghai General Distribution Office of Zhejiang Library in modern times,is one of them.On the basis of a brief description of modern Zhejiang Library and its book publishing,as well as the overview of Huating Bookstore,the paper introduces and analyzes the ZPL Publishing Book Catalogue sent by Huating Bookstore,and the ZPL publishing and selling consignment books issued by Huating Bookstore.It points out that Huating Bookstore is a bridge between the ZPL located in Hangzhou and various retail ZPL publishing bookstores in Shanghai.Their production and sales relationship is a mutually beneficial one.展开更多
Based on several bibliographic advertisements carried in newspapers and magazines from 1919 to 1922 for books published by Peking University Publishing Department,and issued by Yadong Library,the paper analyzes the ch...Based on several bibliographic advertisements carried in newspapers and magazines from 1919 to 1922 for books published by Peking University Publishing Department,and issued by Yadong Library,the paper analyzes the characteristics of the books published by Peking University Publishing Department during this period,and points out that Yadong Library entered its golden period of development due to move from the alley to the main road and obtain the management rights of the books published by Peking University Publishing Department.展开更多
Dear Reader,We regret to inform that there is an overlapping of page numbers(from pages 905 to 917)for the articles in Volume 6/3 as well as Volume 6/4.We sincerely apologise for inconvenience that these pagination er...Dear Reader,We regret to inform that there is an overlapping of page numbers(from pages 905 to 917)for the articles in Volume 6/3 as well as Volume 6/4.We sincerely apologise for inconvenience that these pagination errors have caused.This information is published as Publisher's note.The publisher apologizes for the inconvenience caused.展开更多
Cancer research is occasionally described as being in a reproducibility crisis.The cancer literature has ample papers retracted due to misconduct,including the use of paper mills,invalid authorship,or fake data.The ob...Cancer research is occasionally described as being in a reproducibility crisis.The cancer literature has ample papers retracted due to misconduct,including the use of paper mills,invalid authorship,or fake data.The objective of this paper was to gain an appreciation of the balance of retractions and associated retraction notices of 23 retracted Cancer Biotherapy and Radiopharmaceuticals papers associated with paper mills.By 23 March 2023,these retracted papers had already accumulated 287 citations according to Web of Science Core Collection,253 according to Scopus,and 365 according to Google Scholar,i.e.,metrically speaking,they were highly rewarded.All authors had an affiliation(71%being a hospital)in China.Most(12/21;57%)of corresponding authors had emails with a@163.com suffix.Four of the retraction notices(i.e.,17%)explicitly indicated paper mills as a reason for retraction although,in general,the retraction notices lacked details and background that could assist readers’understanding of the retractions.展开更多
文摘Since 2014,nationwide reading has been included in the government work report for 10 consecutive times,and twice into the country’s five-year development plan.The importance of reading for individuals,society,and the country has become increasingly prominent.National reading has flourished,and throughout the 2018 to 2022 National Reading Survey Report,there have been welcome changes in national reading in China.This study compares and analyzes the relevant reading indicators of adult nationals from 2018 to 2022,and summarizes the five changes and new trends in national reading.That is,national reading awareness has increased,paper-book reading habits have returned,digital reading has become more diversified,the listening group has grown,and the voice of national reading activities has continued to rise.Accordingly,it provides relevant development strategies for publishers.
文摘As suggested by the title, this extensive book is concerned with crack and contact prob- lems in linear elasticity. However, in general, it is intended for a wide audience ranging from engineers to mathematical physicists. Indeed, numerous problems of both academic and tech- nological interest in electro-magnetics, acoustics, solid and fluid dynamics, etc. are actually related to each other and governed by the same mixed boundary value problems from a unified mathematical standpoint
文摘In 2012, the first paper in the series Analytical Methods in Quality Control of Scientific Publications was published in the American Journal of Analytical Chemistry, Vol. 3, No. 6, 2012, pp. 443-447. This paper was mainly based on evidence presented in the 2011 in book Historical Overview of Chromatography and Related Techniques in Analysis of Antimalarial Drug Primaquine (editor Ilia Brondz, Nova Science Publishers, Inc., ISSN 978-1-61761-944-1). The first paper in this series di- scussed issues of obvious falsification and plagiarism contained in paper published by Dongre et al., Applications of GC-EI-MS for the Identification and Investigation of Positional Isomer in Primaquine, an Antimalarial Drug. Journal of Pharmaceutical and Biomedical Analysis, Vol. 39, No. 1-2, 2005, pp. 111-116. Dongre et al. copied their publication from an original research manuscript submitted for consideration by other authors. This paper was published in the Asian Journal of Chemistry, Vol. 17, No. 3, 2005, pp. 1678-1688. Conclusive arguments against the publication of Dongre et al. were presented in the American Journal of Analytical Chemistry, Vol. 3, No. 6, 2012, pp. 443-447. Further cases of general plagiarism and incompetence relating to authors, reviewers, editors, and publishers were presented in Part II in Analytical Methods in Quality Control of Scientific Publications Part II: The Authors’, Reviewers’, Editors’ Responsibility and the Publishers’ Authority in the International Journal of Analytical Mass Spectrometry and Chromatography, Vol. 1, No. 2, 2013, pp. 81-89. The present paper will discuss the following issues: the obvious neglect of the rights of authors by some publishers and editors;how original research manuscripts are exposed to mediocre researchers, and possibly sold, by editors to these “scientists” to boost the image of these particular “scientists”;how the order of authors’ names in published articles are changed to satisfy the commercial interests of companies;and how copyright is breached in an appalling way by well-established publishers. The documents presented here concern research publications in the fields of chromatography, chromatography-mass spectrometry, and mass spectrometry.
文摘From March 12 to 14,2024,the London Book Fair was held at the Olympia Exhibition Centre in London.The fair attracted over 1,000 publishing organizations and more than 30,000 publishing professionals from around the world.Chinese publishing entities promoted fine Chinese books and culture through book displays,multimedia presentations,and exchanges between Chinese and foreign experts,enhancing publishing cooperation and cultural exchange.
文摘[目的/意义]对Open Book Publishers(OBP)出版社学术图书开放获取商业模式的9个构成要素及运作特点展开研究,以期以更细粒化的商业模式研究视角,求解破除图书开放获取困局的办法,并为以学术团体或大学研究机构为主导的同类出版社建立可持续的商业模式提供参考。[方法/过程]从开放获取的研究视角,运用商业画布分析工具及案例分析法,试探究OBP出版社的商业模式构成要素及其耦合机理。[结果/结论]OBP作为全开放出版社能实现微利,其秘籍在于以用户需求为导向,以平台为基础,在明确的客户细分、面向用户需求的价值主张、良好的客户关系、畅通的渠道通路、丰富的内容资源与合作伙伴基础等要素的基础上,实现了供给侧与需求侧的精准匹配,引导实现正向网络外部性效应与聚集效应。OBP商业模式的成功也为我国开展图书开放获取活动提供了有益的启示。
文摘Purpose:This study aims to explore the geography of editors-in-chief to demonstrate which countries exercise the highest-level decision-making in scholarly communication.In addition,the study seeks to investigate the potential relationships between the origin and nationality of academic publishers and the geography of editors-in-chief.Design/methodology/approach:The analysis involves 11,915 journals listed in Web of Science’s Social Sciences Citation Index(SSCI)and Science Citation Index Expanded(SCIE).These journals employ 15,795 scholars as editors-in-chief.The geographical locations of the institutions the editors-in-chief are affiliated with were identified;then,the data were aggregated at the country level.Findings:The results show that most editors-in-chief are located in countries of the Anglosphere,primarily the United States and the United Kingdom.In addition,most academic publishers and professional organizations that publish academic journals were found to be based in the United States and the United Kingdom,where most editors-in-chief are also based.Research limitations:The analysis involves journals indexed in the Web of Science’s SCIE/SSCI databases,which are demonstrably biased toward the English language.Furthermore,the study only takes a snapshot of the geography of editors-in-chief for the year 2022,but it does not investigate trends.Research implications:The study maps the highest-level decision-making in scholarly communication.Originality/value:The study explores and maps the geography of editors-in-chief by using a massive dataset.
文摘Over the years immunotherapy has demonstrably improved the field of cancer treatment.However,achieving long-term survival for colorectal cancer(CRC)patients remains a significant unmet need.Combination immunotherapies incor-porating targeted drugs like MEK or multi-kinase inhibitors have offered some palliative benefit.Nevertheless,substantial gaps remain in the current therapeutic armamentarium for CRC.In recent years,there has been a surge of interest in exploring novel treatment strategies,including the application of light-activated drugs in conjunction with optical devices.This approach holds promise for achie-ving localized and targeted delivery of cytotoxic agents,such as microtubule-targeting drugs,directly to cancerous cells within the colon.
文摘INTRODUCTION,Types of paper,Submission Checklist,BEFORE YOU BEGIN,Ethics in publishing,Ethics Consent,Publication Consent,Studies in humans and animals,Declaration of interest,Submission declaration and verification,Use of inclusive language,Preprints,Authors contributions,Changes to authorship。
基金Supported by Shanghai Natural Science Foundation,No.22ZR1455900Shanghai Putuo District Health System Science and Technology Innovation Project Key Project,No.ptkwws202201and Shanghai Putuo District Xinglin Excellent Youth Talent Training Program,No.ptxlyq2201.
文摘BACKGROUND The annual incidence of metabolic-associated fatty liver disease(MAFLD)in China has been increasing and is often overlooked owing to its insidious charac-teristics.Approximately 50%of the patients have a normal weight or are not obese.They are said to have lean-type MAFLD,and few studies of such patients are available.Because MAFLD is associated with abnormal lipid metabolism,lipid-targeted metabolomics was used in this study to provide experimental evidence for early diagnosis and pathogenesis.MAFLD and analyze metabolic pathways.UPLC-Q-Orbitrap/MS content determination was used to determine serum palmitic acid(PA),oleic acid(OA),linoleic acid(LA),and arachidonic acid(AA)levels in lean-type MAFLD patients.RESULTS Urea nitrogen and uric acid levels were higher in lean-type MAFLD patients than in healthy individuals(P<0.05).Alanine transaminase and cholinesterase levels were higher in lean-type MAFLD patients than in healthy indi-viduals(P<0.01).The expression of high-density lipoprotein and apolipoprotein A-1 were lower in lean-type MAFLD patients than in healthy individuals(P<0.05)and the expression of triglycerides and fasting blood glucose were increased(P<0.01).A total of 65 biomarkers that affected the synthesis and metabolism of fatty acids were found with P<0.05 and variable importance in projection>1.The levels of PA,OA,LA,and AA were significantly increased compared with healthy individuals.CONCLUSION The metabolic profiles of lean-type MAFLD patients and healthy participants differed significantly,yielding 65 identified biomarkers.PA,OA,LA,and AA exhibited the most significant changes,offering valuable clinical guidance for prevention and treatment of lean-type MAFLD.
文摘BACKGROUND Heart failure(HF),a common cardiovascular condition,is characterized by significant morbidity and mortality.While traditional Chinese medicine(TCM)is often used as a complementary approach in HF management,systematic evalua-tions of its impact on clinical outcomes,TCM syndrome scores,and B-type natriuretic peptide(BNP)levels are lacking.This study fills this gap through a comprehensive analysis of randomized controlled trials(RCTs)focusing on TCM for HF treatment.It encompasses an assessment of methodological quality,a meta-analysis,and an evaluation of evidence quality based on established standards.The results offer crucial insights into the potential advantages and constraints of TCM in HF management.RCTs on TCM for HF treatment published since the establishment of the database were searched in four Chinese and English databases,including China National Knowledge Infrastructure,Wanfang,VIP Information Chinese Science and Technology Journal,and PubMed.Methodological quality was assessed for the included studies with the Cochrane risk-of-bias assessment tool,and the meta-analysis and publication bias assessment was performed with the RevMan5.3 software.Finally,the quality of evidence was rated according to the GRADE criteria.RESULTS A total of 1098 RCTs were initially retrieved.After screening,16 RCTs were finally included in our study,which were published between 2020 and 2023.These RCTs involved 1660 HF patients,including 832 in the TCM group[TCM combined with conventional Western medicine(CMW)treatment]and 828 in the CWM group(CWM treatment).The course of treatments varied from 1 wk to 3 months.TCM syndrome differentiation was analyzed in 11 of the included RCTs.In all included RCTs,outcome indicators included comprehensive clinical outcomes,TCM syndrome scores,and BNP levels.The meta-analysis results showed significant differences between the TCM and CWM groups in terms of comprehensive clinical outcomes[risk ratio=-0.54;95%confidence interval(CI)=-0.61,-0.47;P<0.00001],TCM syndrome scores[weighted mean difference(WMD)=-142.07;95%CI=-147.56,-136.57;P<0.00001],and BNP levels(WMD=-142.07;95%CI=-147.56,-136.57;P<0.00001).According to the GRADE criteria,RCTs where"TCM improves clinical comprehensive outcomes"were rated as low-quality evidence,and RCTs where"TCM reduces TCM syndrome scores"or"TCM decreases BNP levels"were rated as medium-quality evidence.CONCLUSION TCM combined with CWM treatment effectively improves comprehensive clinical outcomes and diminishes TCM syndrome scores and BNP levels in HF patients.Given the low and medium quality of the included RCTs,the application of these results should be cautious.
基金Doctoral research start-up fund of Guangxi Normal UniversityGuangzhou Research Institute of Communication University of China Common Construction Project,Sunflower-the Aging Intelligent CommunityGuangxi project of improving Middle-aged/Young teachers'ability,Grant/Award Number:2020KY020323。
文摘The overgeneralisation may happen because most studies on data publishing for multiple sensitive attributes(SAs)have not considered the personalised privacy requirement.Furthermore,sensitive information disclosure may also be caused by these personalised requirements.To address the matter,this article develops a personalised data publishing method for multiple SAs.According to the requirements of individuals,the new method partitions SAs values into two categories:private values and public values,and breaks the association between them for privacy guarantees.For the private values,this paper takes the process of anonymisation,while the public values are released without this process.An algorithm is designed to achieve the privacy mode,where the selectivity is determined by the sensitive value frequency and undesirable objects.The experimental results show that the proposed method can provide more information utility when compared with previous methods.The theoretic analyses and experiments also indicate that the privacy can be guaranteed even though the public values are known to an adversary.The overgeneralisation and privacy breach caused by the personalised requirement can be avoided by the new method.
文摘In 2023,Baishideng Publishing Group(Baishideng)routinely published 47 openaccess journals,including 46 English-language journals and 1 Chinese-language journal.Our successes were accomplished through the collective dedicated efforts of Baishideng staffs,Editorial Board Members,and Peer Reviewers.Among these 47 Baishideng journals,7 are included in the Science Citation Index Expanded(SCIE)and 6 in the Emerging Sources Citation Index(ESCI).With the support of Baishideng authors,company staffs,Editorial Board Members,and Peer Reviewers,the publication work of 2023 is about to be successfully completed.This editorial summarizes the 2023 activities and accomplishments of the 13 SCIEand ESCI-indexed Baishideng journals,outlines the Baishideng publishing policy changes and additions made this year,and highlights the unique advantages of Baishideng journals.
文摘Journal of Acute Disease(JAD)is a bimonthly international medical journal dedicated to promoting and disseminating original,peer-reviewed work in the field of acute attack of all kinds of diseases,including pre hospital and hospital emergency medicine,disaster medicine,critical diseases,acute diseases and related medical specialties by publishing high quality scientific and clinical research worldwide.
基金This study is a phased achievement of the“Research on Innovative Communication of Romance of the Three Kingdoms under Audio Empowerment”project(No.23ZGL16)funded by Zhuge Liang Research Center,a key research base of social sciences in Sichuan Province.
文摘Visual media have dominated sensory communications for decades,and the resulting“visual hegemony”leads to the call for the“auditory return”in order to achieve a holistic balance in cultural acceptance.Romance of the Three Kingdoms,a classic literary work in China,has received significant attention and promotion from leading audio platforms.However,the commercialization of digital audio publishing faces unprecedented challenges due to the mismatch between the dissemination of long-form content on digital audio platforms and the current trend of short and fast information reception.Drawing on the Business Model Canvas Theory and taking Romance of the Three Kingdoms as the main focus of analysis,this paper argues that the construction of a business model for the audio publishing of classical books should start from three aspects:the user evaluation of digital audio platforms,the establishment of value propositions based on the“creative transformation and innovative development”principle,and the improvement of the audio publishing infrastructure to ensure the healthy operation and development of the digital audio platforms and consequently improve their current state of development and expand the boundaries of cultural heritage.
基金Humanities and Social Sciences Planning Fund Project of the Ministry of Education of P.R.China,titled“Research on the Books Publishing of Modern Chinese Libraries from the Perspective of Generalized Technology”(Project No.19YJA870014).
文摘The paper is based on literature search,introducing and analyzing the book publishing situation of modern Peking University Library from the perspective of the publisher being Peking University Library and its predecessor.It is pointed out that the majority of the book printing methods published by the modern Peking University Library are lead printing,and among the types of Chinese library classification,catalogue of library collections is the most common.
基金the research results of Humanities and Social Science Planning Fund Project of the Ministry of Education of P.R.China,titled“Research on the Books Publishing of Modern Chinese Library from the Perspective of Generalized Technology”(Project number:19YJA870014).
文摘Many modern Chinese libraries have established distribution agencies in other cities to distribute books published or sold on consignment.Huating Bookstore,which was once the Shanghai General Distribution Office of Zhejiang Library in modern times,is one of them.On the basis of a brief description of modern Zhejiang Library and its book publishing,as well as the overview of Huating Bookstore,the paper introduces and analyzes the ZPL Publishing Book Catalogue sent by Huating Bookstore,and the ZPL publishing and selling consignment books issued by Huating Bookstore.It points out that Huating Bookstore is a bridge between the ZPL located in Hangzhou and various retail ZPL publishing bookstores in Shanghai.Their production and sales relationship is a mutually beneficial one.
基金part of the research results of Humanities and Social Science Planning Fund Project of the Ministry of Education of P.R.China,titled“Research on the Books Publishing of Modern Chinese Library From the Perspective of Generalized Technology”(Project No.19YJA870014).
文摘Based on several bibliographic advertisements carried in newspapers and magazines from 1919 to 1922 for books published by Peking University Publishing Department,and issued by Yadong Library,the paper analyzes the characteristics of the books published by Peking University Publishing Department during this period,and points out that Yadong Library entered its golden period of development due to move from the alley to the main road and obtain the management rights of the books published by Peking University Publishing Department.
文摘Dear Reader,We regret to inform that there is an overlapping of page numbers(from pages 905 to 917)for the articles in Volume 6/3 as well as Volume 6/4.We sincerely apologise for inconvenience that these pagination errors have caused.This information is published as Publisher's note.The publisher apologizes for the inconvenience caused.
文摘Cancer research is occasionally described as being in a reproducibility crisis.The cancer literature has ample papers retracted due to misconduct,including the use of paper mills,invalid authorship,or fake data.The objective of this paper was to gain an appreciation of the balance of retractions and associated retraction notices of 23 retracted Cancer Biotherapy and Radiopharmaceuticals papers associated with paper mills.By 23 March 2023,these retracted papers had already accumulated 287 citations according to Web of Science Core Collection,253 according to Scopus,and 365 according to Google Scholar,i.e.,metrically speaking,they were highly rewarded.All authors had an affiliation(71%being a hospital)in China.Most(12/21;57%)of corresponding authors had emails with a@163.com suffix.Four of the retraction notices(i.e.,17%)explicitly indicated paper mills as a reason for retraction although,in general,the retraction notices lacked details and background that could assist readers’understanding of the retractions.